Now's the time to find innovation opportunities in a trustless world, says this Houston expert

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A Houston expert reflects on the rollercoaster of a time the past year has been — and why its ripe with opportunities. Photo via Getty Images

Hidden beneath all the recent events in the technology work, stock market, political landscape, and most of the social problems we see today lies one underlying trend. A trend so powerful that it's causing disruption in nearly every institution out there, and changing the business landscape faster than anyone can keep up.

Trust is gone. I mean completely gone.

At this point, the examples of this are too numerous to list but let's look at the past several months in the United States. In that short period, we saw an incredibly contentious election process, big tech disable the primary communication of a world leader, a mass exodus do decentralized messaging, an explosion in the defi industry and crypto, and a once promising vaccine process somehow not be effective despite being the primary conversation topic for everyone.

And this was all before a bunch of social media users treated the world's greatest stock market like a game, and far after we saw a country divided into two by racial movements, and we have yet to even get to things such as the Russian hacks.

We're left with an absolute mess of a situation where every social contract seems to be broken and the default response to any sort of central authority is being reevaluated. Without doubt we'll eventually figure out some great long-term answers, but at the speed at which the business world works today, it's going to be messy.

Luckily, mess creates opportunity and within all this disruption lies many golden nuggets of opportunity. The last twelve months was likely a watershed moment in key areas and as innovators, and business people — and it's our job to find them. It's what we signed up for and, for many of us, why we do what we do.

If there was ever a time to invest heavily in innovative technologies, today is it. Most of the time businesses are very resistant to change. Their default answer is always "no," and this puts innovators in a constant search of early adopters. But today, we see a different landscape. Businesses of all sizes and industries have been tossed around like a toy ship in an ocean. They do not know which way is up and business as usual seems like an old campfire story. Everyone, everywhere is looking for creative ideas to improve their business, and creative ideas is at the heart of true entrepreneurship and innovation.

Within this disruption also lies a few other key support pillars that should benefit all innovative minded individuals.

  • Despite terrible economic conditions, those invested in tech over the past year have done incredibly well. These individuals should be primed to reinvest their profits into bigger wins.
  • The workforce is truly global, and people are scrambling. The ideas of location being an advantage to hiring is truly disappearing. This means talent acquisition costs are falling through the floor and availability through the ceiling.
  • Consumers and businesses alike have been introduced to new technology so the legwork of explaining things such as defi and blockchain is much easier. It's also easy to find numerous use cases for anything involving proximity, health, privacy, and security.
  • The new administration will be eager to find wins, and invest money in different technologies than the previous. No matter what you think politically about this strategy, the reality is that areas such as healthcare, education, and will offer innovation opportunities. Even regulation itself, which we are likely to see increased, can be a great playground for innovation.

Twenty years ago, the way that business was done is unrecognizable in some industries. Many of the successful business today did not even exist then. Technology has a tendency to change things exponentially so imagine what the next ten years will look like. What are we not seeing today that will be the new business as usual?

The future is ours to create

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Cody Caillet is the founder at Gulf Coast Solutions, a Houston-based technology firm with speed-to-value approach in delivering business technology to impact top-line and bottom-line numbers for a business.

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

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