These three startups are innovating flood damage mitigation tools so that Houstonians can have peace of mind this hurricane season. Getty Images

In light of Houston's frequent floods, a local organization has formed to encourage innovation in resiliency — especially as the city moves throughout the 2020 hurricane season.

The Gulf Coast & Southwest Resilience Innovation Hub was founded last month by the Insurance Information Institute and ResilientH20 Partners in The Cannon's downtown location. The organization is looking into the best innovations within resiliency — especially as it pertains to Houston, where nine of the 10 most expensive hurricanes in the United States have occurred in the past 16 years.

"There has been a widespread interest in, and demand for, best-in-class actionable, alternative disaster mitigation solutions since 2017's Hurricane Harvey and subsequent storms caused extensive insured losses to autos, homes, businesses, and governmental properties," says Richard Seline, managing partner of ResilientH2O Partners, in a news release.

The organization held a virtual panel and pitch session that featured three flood-focused startups. Here are the three companies and their innovative solutions to flood mitigation.

True Flood Risk

True Flood Risk uses machine learning and artificial intelligence to assess a home's flood risk. Image via truefloodrisk.com

Shelly Klose founded her company, True Flood Risk, after she observed Hurricane Sandy devastating New Jersey. But, she wondered, why some homes were hit harder than others. So, she created an artificial intelligence-driven property risk management platform that would easily indicate how susceptible to flood damage each home is. The company even has a way to measure the property's first-floor height based street view images.

"With this key data point for structural height coupled with ground elevation and flood zone data, you have a good indication if that property is at risk," Klose says.

The New York-based company allows users to run their address and learn about their flood damage risk for free — and that's something Klose says thats a tool she's seen used more frequently amid the pandemic.

"What we're finding is people have been so emotionally and financially hit so hard during this pandemic," Klose says. "The last thing you want to do is lose your house."

FloodFrame

Self-deploying flood protection for buildings

FloodFrame is a self-deploying flood protection for buildings. Photo via floodframe.com

Part of the challenge of mitigating flood damage is that it can happen in an instant with little to no warning. FloodFrame provides a solution to that in its self-inflating technology that can detect and prevent flood damage.

FloodFrame works by using buoyancy. A lightweight cloth is wrapped around a tube is installed underground outside the perimeter of your home or business. One end of that cloth is attached to a box that is also installed underground. As flooding begins, an automatic system will release the lids to deploy the inflation of the tube that will protect the structure. When the flood comes in, the system will float on top of the flood — kind of like a pool noodle — and protect the structure from the water. It's easier to install than raising a house, for instance, and can be reused as a long-term solution.

Tasha Nielsen launched the U.S. iteration of FloodFrame — which originated in Denmark — by becoming the company's first franchisee. Now, that process how the company plans to grow and expand and Nielsen is working with home builders and contractors to provide the invention in new homes and buildings. Nielsen also hopes to work with insurance companies, since the device helps prevent costly payouts.

Climaguard

A waterproof container for your car.

Houston-based ClimaGuard is looking to help drivers protect their vehicles from floods. Photo via ClimaGuard/Facebook

Hundreds of thousands of cars were damaged during Hurricane Harvey, and those car owners faced financial burdens from having to find temporary transportation to repairing or even buying a new vehicle. Rahel Abraham, who lost her car during the storm, founded Houston-based ClimaGuard to help enable people to help protect their cars or possessions from the elements.

"We're providing a resilient, practical, and real-time solution," says Abraham.

The tool is easy to use and affordable, considering the costs of potential damages, with a starting price of $399. The average insurance payout for vehicles was $12,000, Abraham says, so it's actually a great risk mitigation tool for auto insurers.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Play it back: Houston home tech startup begins 2025 with fresh funding

HOUSTON INNOVATORS PODCAST EPISODE 272

One of the dozen or so Houston startups kicking of the new year with fresh funding is SmartAC.com, a company that's designed a platform that enables contractors in the HVAC and plumbing industries to monitor, manage, and optimize their maintenance memberships through advanced sensors, AI-driven diagnostics, and proactive alerts.

Last month, the SmartAC.com raised a follow-on round with support from local investor Mercury to continue growth and expansion of the product, which has evolved on many ways since the company launched in 2020, emerging from stealth with $10 million raised in a series A. In a May 2023 interview for the Houston Innovators Podcast, Founder and CEO Josh Teekell explained how he embraced the power of a pivot.

The company's sensors can monitor all aspects of air conditioning units and report back any issues, meaning homeowners have quicker and less costly repairs. While SmartAC.com started with providing the service and tech to homeowners directly, Teekell says he's had a greater interest in working with plumbers and HVAC companies who then deploy the technology to their customers.

"It became quite evident that homeowners don't care about air conditioning really at all until their system breaks," Teekell says on the show. "The technology is really built around giving those contractors as another way to gain a customer relationship and keep it."

Revisit the podcast episode below where Teekell talks about SmartAC.com's last raise.

SmartAC.com's previous round in 2023 — a $22 million series B — was used grow its team that goes out to deploy the technology and train the contractors on the platform.

"We've been very fortunate to get some of the biggest names in Houston on our cap table," Teekell says in the May 2023 conversation. "Since we're raising a bunch of money locally, everyone understands what a pain air conditioning can be."

Houston biotech company tests hard-to-fight cancer therapeutics

fighting cancer

A Houston-based, female-founded biotech company has developed a treatment that could prove to be an effective therapy for a rare blood cancer.

Cellenkos Therapeutics has completed promising Phase 1b testing of its Treg cell therapy, CK0804, in the fight against myelofibrosis. According to a news release from the Cellenkos team, the use of its cord-blood-derived therapeutics could signal a paradigm shift for the treatment of this hard-to-fight cancer.

Cellenkos was founded by MD Anderson Cancer Center physician and professor Simrit Parmar. Her research at the hospital displayed the ability of a unique subset of T cells’ capability to home in on a patient’s bone marrow, restoring immune balance, and potentially halting disease progression.

Myelofibrosis has long been treated primarily with JAK (Janus Kinase) inhibitors, medications that help to block inflammatory enzymes. They work by suppressing the immune response to the blood cancer, but don’t slow the progression of the malady. And they’re not effective for every patient.

“There is a significant need for new therapeutic options for patients living with myelofibrosis who have suboptimal responses to approved JAK inhibitors,” Parmar says. “We are greatly encouraged by the safety profile and early signs of efficacy observed in this patient cohort and look forward to continuing our evaluation of the clinical potential of CK0804 in our planned expansion cohort.”

The expansion cohort is currently enrolling patients with myelofibrosis. What exactly are sufferers dealing with? Myelofibrosis is a chronic disease that causes bone marrow to form scar tissue. This makes it difficult for the body to produce normal blood cells, leaving patients with fatigue, spleen enlargement and night sweats.

Myelofibrosis is rare, with just 16,000 to 18,500 people affected in the United States. But for patients who don’t respond well to JAKs, the prognosis could mean a shorter span than the six-year median survival rate outlined for the disease by Cleveland Clinic.

Helping myelofibrosis patients to thrive isn’t the only goal for Cellenkos right now.

The company seeks to aid people with rare conditions, particularly inflammatory and autoimmune disorders, with the use of CK0804, but also other candidates including one known as CK0801. The latter drug has shown promising efficacy in aplastic anemia, including transfusion independence in treated patients.

The company closed its $15 million series A round led by BVCF Management, based in Shanghai, in 2021. Read more here.

Pioneering Houston biotech startup expands to Brazil for next phase

On the Move

Houston biotech company Cemvita has expanded into Brazil. The company officially established a new subsidiary in the country under the same name.

According to an announcement made earlier this month, the expansion aims to capitalize on Brazil’s progressive regulatory framework, including Brazil’s Fuel of the Future Law, which was enacted in 2024. The company said the expansion also aims to coincide with the 2025 COP30, the UN’s climate change conference, which will be hosted in Brazil in November.

Cemvita utilizes synthetic biology to transform carbon emissions into valuable bio-based chemicals.

“For decades Brazil has pioneered the bioeconomy, and now the time has come to create the future of the circular bioeconomy,” Moji Karimi, CEO of Cemvita, said in a news release. “Our vision is to combine the innovation Cemvita is known for with Brazil’s expertise and resources to create an ecosystem where waste becomes opportunity and sustainability drives growth. By joining forces with Brazilian partners, Cemvita aims to build on Brazil’s storied history in the bioeconomy while laying the groundwork for a circular and sustainable future.”

The Fuel of the Future Law mandates an increase in the biodiesel content of diesel fuel, starting from 15 percent in March and increasing to 20 percent by 2030. It also requires the adoption of Sustainable Aviation Fuel (SAF) and for domestic flights to reduce greenhouse gas emissions by 1 percent starting in 2027, growing to 10 percent reduction by 2037.

Cemvita agreed to a 20-year contract that specified it would supply up to 50 million gallons of SAF annually to United Airlines in 2023.

"This is all made possible by our innovative technology, which transforms carbon waste into value,” Marcio Da Silva, VP of Innovation, said in a news release. “Unlike traditional methods, it requires neither a large land footprint nor clean freshwater, ensuring minimal environmental impact. At the same time, it produces high-value green chemicals—such as sustainable oils and biofuels—without competing with the critical resources needed for food production."

In 2024, Cemvita became capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita quadrupled output at its Houston plant. The company had originally planned to reach this milestone in 2029.

---

This story originally appeared on our sister site, EnergyCapitalHTX.