Houston attracted 31 new corporate headquarters from 2018 to 2024, according to a new report from CBRE. Photo via Getty Images

The Houston area already holds the title as the country’s third biggest metro hub for Fortune 500 headquarters, behind the New York City and Chicago areas. Now, Houston can tout another HQ accolade: It’s in a fourth-place tie with the Phoenix area for the most corporate headquarters relocations from 2018 to 2024.

During that period, the Houston and Phoenix areas each attracted 31 corporate headquarters, according to new research from commercial real estate services company CBRE. CBRE’s list encompasses public announcements from companies across various sizes and industries about relocating their corporate headquarters within the U.S.

Of the markets included in CBRE’s study, Dallas ranked first for corporate relocations (100) from 2018 to 2024. It’s followed by Austin (81), Nashville (35), Houston and Phoenix (31 each), and Denver (23).

According to CBRE, reasons cited by companies for moving their headquarters include:

  • Access to lower taxes
  • Availability of tax incentives
  • Proximity to key markets
  • Ability to support hybrid work

“Corporations now view headquarters locations as strategic assets, allowing for adaptability and faster reaction to market changes,” said CBRE.

Among the high-profile companies that moved their headquarters to the Houston area from 2018 to 2024 are:

  • Chevron
  • ExxonMobil
  • Hewlett-Packard Enterprise
  • Murphy Oil

Many companies that have shifted their headquarters to the Houston area, such as Chevron, are in the energy sector.

“Chevron’s decision to relocate its headquarters underscores the compelling advantages that position Houston as the prime destination for leading energy companies today and for the future,” Steve Kean, president and CEO of the Greater Houston Partnership, said in 2024. “With deep roots in our region, Chevron is a key player in establishing Houston as a global energy leader. This move will further enhance those efforts.”

According to CBRE, California (particularly the San Francisco Bay and Los Angeles areas) lost the most corporate HQs in 2024, with 17 companies announcing relocations—12 of them to Texas. Also last year, Texas gained nearly half of all state-to-state relocations.

In March, Site Selection magazine awarded Texas its 2024 Governor’s Cup, resulting in 13 consecutive wins for the state with the most corporate relocations and expansions.

In a news release promoting the latest Governor’s Cup victory, Gov. Greg Abbott hailed Texas as “the headquarters of headquarters.”

“Texas partners with the businesses that come to our great state to grow,” Abbott said. “When businesses succeed, Texas succeeds.”

CBRE explained that the trend of corporate HQ relocations reflects the desire of companies to seek new environments to support their goals and workforce needs.

“Ultimately, companies are seeking to establish themselves in locations with potential for long-term success and profitability,” CBRE said.

Texas Gov. Greg Abbott signed the document in London alongside U.K. Trade Secretary Kemi Badenoc. Photo via LinkedIn

UK, Texas pledge closer trade ties in recently signed agreement

doing business

Britain signed a trade agreement with Texas on Wednesday, the eighth the U.K. has inked with a U.S. state in the absence of a wider free trade deal with the U.S. government.

Texas Gov. Greg Abbott signed the document in London alongside U.K. Trade Secretary Kemi Badenoch. Abbott also met with Prime Minister Rishi Sunak, who told him it was an “exciting moment.”

The "statement of mutual cooperation” is not a full trade deal because individual U.S. states do not have the power to sign those, but it commits Britain and Texas to improve cooperation between businesses and tackle regulatory barriers to trade.

“Understand that this is far more than a document,” Abbott said. “What we signed our names to today is a pathway to increased prosperity.”

During and after Britain’s 2016 referendum on European Union membership, supporters of Brexit argued that a chief benefit of leaving the bloc, and its vast free market of almost half a billion people, was the chance for the U.K. to make new trade deals around the world.

U.K.-U.S. trade talks were launched with fanfare soon after Britain left the EU in 2020, but negotiations faltered amid rising concern in the U.S. administration about the impact of Brexit, especially on Northern Ireland.

Instead, Britain has resorted to signing agreements with states including Florida, Indiana and North Carolina.

Although these agreements do not lower tariffs, as a free trade deal would, they can provide some help for businesses through recognizing U.K. qualifications or addressing state-level regulatory issues.

The friendship state is also known for its business friendliness — for 19 years running, according to one report. Photo via Getty Images

Texas continues its reign as the top state for business

We're No. 1

The Texas business sector has a pretty impressive winning streak when its compared to the rest of the country.

For the 19th consecutive year, CEOs surveyed by Chief Executive magazine have named Texas the best state for business. For its annual survey, the magazine questions CEOs about each state’s business climate, workforce, and quality of life.

“The state’s combination of business-friendly policies, growing cities, a rising professional class, and a direct appeal to CEOs who aren’t happy with California continues to keep Texas at the head of the class,” the magazine says.

Texas Gov. Greg Abbott touted the Chief Executive honor in a recent news release.

“Texas is attractive to CEOs and their businesses because we offer the freedom and opportunity that cannot be found elsewhere: no state income tax; a stable, predictable regulatory structure; and a young, educated, and growing workforce ready to take on the jobs of tomorrow,” the governor says. “Workers know that in Texas you can find a good home, a great education for your children, and plenty of companies that provide an ample income to support their family.”

The Chief Executive accolade comes almost two months after Texas claimed its 11th straight Governor’s Cup from Site Selection magazine. The Governor’s Cup recognizes the nation’s top-performing state for job-creating business relocations and expansions.

“Texas truly is America’s economic engine, and we stand apart as a model for the nation,” Abbott said in a March 2023 news release about the Governor’s Cup victory.

Another report, from business credit card experts Capital on Tap, deemed Texas as the second best state to start a small business, right after Florida. They retrieved their data from the U.S. Bureau of Labor Statistics based on several factors, including new firm survival rates, corporate tax rates, the number of entrepreneurs per state, and more. The Lone Star State's friendly tax framework and lack of income tax was among the reasons cited by that study. Additionally, if a small business owner in Texas needed to take out a loan, they’d be able to secure $4,811 per employee, which is the fifth-highest average loan amount in a calculation of all 50 states.

Meanwhile, WalletHub, a personal finance resource website, ranked Texas as the third best state to start a business in its recent list, 2023's Best & Worst States to Start a Business, with a score of 56.85 points. Texas ranked behind Utah, No. 1, and Florida, No. 2, and just ahead of Colorado. Idaho, Georgia, Arizona, Nevada, Oklahoma, and California make up the rest of the top 10, respectively.

Whatever the study, Texas ranks high on any list of states recognized for their business climate.

Vicki Hollub has been appointed chairwoman of the Texas Economic Development Corp. Photo via Oxy

Houston energy exec named to statewide position

mover and shaker

Vicki Hollub, president and CEO of Houston-based oil and gas company Occidental Petroleum, has been appointed chairwoman of the Texas Economic Development Corp.

Hollub, who lives in Galveston, had been vice chairwoman of TxEDC, a privately funded nonprofit that collaborates with the state-funded Governor’s Office of Economic Development and Tourism to promote Texas as a business location. She succeeds Temple businessman Drayton McLane Jr., former owner of the Houston Astros, as chair of the Austin-based organization.

Hollub became the first woman to lead a major American oil and gas company when she was tapped as Occidental’s president and CEO in 2016. She has worked at Occidental for 35 years.

In a 2020 interview, Hollub outlined Occidental’s future as a “carbon management company.”

“Ultimately, I don’t know how many years from now, Occidental becomes a carbon management company, and our oil and gas would be a support business unit for the management of that carbon. We would be not only using [CO2] in oil reservoirs [but] capturing it for sequestration as well,” Hollub said.

Aside from elevating Hollub to the role of chairwoman, Gov. Greg Abbott has named Houston’s Mauricio Gutierrez to the TxEDC board of directors. Gutierrez is president and CEO of Houston-based NRG Energy.

Abbott’s office also made two other recent business-related announcements involving the Houston area:

  • Workforce development grants from the Texas Talent Connection program were awarded to Alvin Community College, the Bay Area Houston Advanced Technology Consortium, Capital IDEA of Houston, Lone Star College, the University of Houston – Downtown, and Volunteers of America.
  • Grants for science, technology, engineering, and math (STEM) summer youth camps were awarded to Lone Star College – Tomball, the University of Houston – Clear Lake, Brazosport College, the San Jacinto Community College District, and Houston Community College.
We're all work and no play. Photo courtesy of AFlags

Texas clocks in among 5 hardest-working states in America, study shows

labor of love

With a nod to disco diva Donna Summer, Texans work hard for the money.

A new study from personal finance website WalletHub puts Texas at No. 5 among the hardest-working states, down one spot from No. 4 in last year's study. Ahead of Texas are, in descending order, Alaska, North Dakota, Nebraska, and South Dakota.

To determine where Americans work the hardest, WalletHub compared the 50 states across 10 key indicators. Those factors include average number of workweek hours, share of workers with multiple jobs, and annual number of volunteer hours per resident.

Boosting Texas on this list is the state's average number of workweek hours. The Lone Star State ranks fourth in that category.

Texas also ranks high for the following:

     
  • Share of workers who leave vacation time unused (No. 11).
  • Share of workers who are "engaged" (No. 5).

Texas ranks low for the share of workers with multiple jobs (No. 46) and the employment rate (No. 39).

More than 13.2 million Texans were employed in July in the state's civilian workforce, according to the U.S. Bureau of Labor Statistics. That month, the statewide unemployment rate stood at 6.2 percent. The civilian workforce includes people who are inmates, agricultural workers, and federal employees, but not those who are active-duty military personnel.

In July, Gov. Greg Abbott lauded the state's "young, growing, and skilled workforce" for helping forge a "diversified and resilient economy."

"The Texas economy is booming. Businesses are investing in the Lone Star State at a record pace because we've built a framework that allows free enterprise to flourish and hardworking Texans to prosper," Abbott said.

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This article originally ran on CultureMap.

How's startup life in Texas? Well, it's the best in the nation, according to a new ranking. Photo via Getty Images

Report: Texas ranks as the best state to start a business

lone star startups

If you're a Texan looking to launch a startup, you appear to be in the right place.

Personal finance website WalletHub puts Texas at No. 1 in its new ranking of the best and worst states for starting a business. Across the 50 states, WalletHub compared 28 key indicators of startup success to come up with the list.

In the general bucket for "business environment," Texas ranked second. It dropped to 12th in the "access to resources" category and 32nd in the "business costs" category. Digging deeper, Texas appears at No. 4 for the average length of the workweek, No. 5 for the highest total spending on incentives as a percentage of GDP, and No. 6 for average growth in number of small businesses. However, Texas scored a below-average 29th-place ranking for labor costs.

"Choosing the right state for a business is … crucial to its success," WalletHub explains. "A state that provides the ideal conditions for business creation — access to cash, skilled workers, and affordable office space, for instance — can help new ventures not only take off but also thrive."

The WalletHub accolade follows a handful of other recent plaudits for Texas' business-friendly environment.

In March, Site Selection magazine awarded its Governor's Cup to Texas. The Governor's Cup honors the top states for job creation and capital investment.

"Despite the challenges faced from the COVID-19 pandemic, we've seen what Texas can achieve when we foster an environment that empowers people to succeed," Gov. Greg Abbott said in a statement about the Governor's Cup win. "The Texas model continues to inspire entrepreneurs and innovators and attract job creators from across the country, and I look forward to spurring more job growth and opportunity for all Texans in every corner of our great state."

A month later, Chief Executive magazine crowned Texas the best state for business for the 17th consecutive year.

But Texas ranked fourth in CNBC's recent rundown of the top states for business in 2021. "A fourth-place finish would be good for most states, but not Texas. This year's finish ties for the worst-ever for the four-time Top State, which last won in 2018," CNBC says.

CNBC says Texas finished fourth based on the strength of its workforce and economy.

"But Texas was hurt this year by policies that run counter to the study's increased focus on inclusiveness," adds CNBC, pointing out that Abbott is pressing ahead with these policies during the current special session of the Texas Legislature.

Abbott's agenda for the special session includes legislation that critics view as watering down voting rights, attacking public school education about racism, and punishing transgender competitors in school sports. Supporters say these measures would preserve election integrity, strip critical race theory from public education in Texas, and protect females participating in school sports whose gender identity aligns with their birth gender.

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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.