UHD's science building has received funding from a nonprofit affiliate of Green Mountain Energy to install green energy technology. Courtesy of NRG

The University of Houston-Downtown has gotten some green to make its new College of Sciences & Technology Building even more green.

The Green Mountain Energy Sun Club, a nonprofit affiliated with the Green Mountain Energy utility provider, has pledged more than $250,000 to UHD for installation of solar panels at the building, as well as the purchase of photosynthesis equipment.

Akif Uzman, dean of UHD's College of Sciences & Technology, says in a release that the Green Mountain Energy Sun Club gift propels "our drive to show students and our local community our commitment to energy conservation and sustainable energy practices."

By the spring of 2020, UHD will install a 54-panel, 16.7-kilowatt, off-grid solar system that will help power two environmental science teaching labs in the College of Sciences & Technology Building. One of the labs, the Green Mountain Energy Sun Club Environmental Science Lab, will host classes by next year's spring semester.

"Our mission is to change the way power is made, and we share UHD's dedication to renewable energy, environmental education, and reducing carbon emissions," Mark Parsons, vice president and general manager of Houston-based Green Mountain Energy, says in a release.

Houston-based NRG Energy owns Green Mountain Energy.

Donations to the Sun Club come from Green Mountain Energy and its customers and employees. Since 1997, Green Mountain Energy has promoted energy efficiency, conservation, and environmental stewardship.

The Sun Club gift also will help buy a portable photosynthesis system. Michael Tobin, associate professor of biology, says the equipment will take measurements of plants in courses such as Plant Biology Laboratory, General Ecology Laboratory, and Environmental Lab and Field Studies. In addition, it will be used by students conducting faculty-guided research projects.

"A research-grade instrument to make photosynthesis and water use measurements will enhance students' research experiences and increase the likelihood that their project results can be published in a peer-reviewed scientific journal," Tobin says in a release.

UHD opened the College of Sciences & Technology Building in August. It's the first University of Houston System building constructed to meet LEED Gold standards, reflecting a commitment to sustainability features such as energy-efficient lighting, recycled construction materials, and "smart" design components.

Spanning 105,000 square feet, the College of Sciences & Technology Building contains nearly 30 labs for teaching and research, as well as classrooms, meeting and study spaces, and a café. UHD envisions the building will be a "model for sustainability in Houston."

Environmental highlights of the building include a 6,000-gallon cistern that provides water for the outdoor urban gardens, and the addition of native grasses in the surrounding landscape to create a micro-pocket prairie and, in effect, an outdoor classroom.

Aside from classes and resources for students and faculty in biology, biotechnology, biological and physical sciences, and chemistry, the building houses UHD's Center for Urban Agriculture & Sustainability.

The center is "a game changer for UHD initiatives and scholarly activities centered on sustainability," Lisa Morano, director of the Center for Urban Agriculture & Sustainability, says in a release. "It also serves as an example of how planners and architects can incorporate environmentally sound decisions in the design and construction of academic facilities."

Juan Sánchez Muñoz, president of UHD, says the College of Sciences & Technology Building is a hub for academic exploration and a catalyst for community collaboration.

"Its labs and learning spaces will elevate UHD's ability to prepare the next generation of Houston's scientists and innovators. The facility also will serve as a place where Houstonians can gather to address issues affecting our city and to learn how UHD is leading positive change in the region," Muñoz says in a release. "It's a major addition to our campus and an incredible asset to Houston."

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."