Two Houston-based companies made it into this new clean tech accelerator. Photo via greentownlabs.com

The Low-Carbon Hydrogen Accelerator announced its inaugural class of clean tech startups — two of which hail from right here in Hosuton.

In all, seven startups have been chosen to participate this year in the Low-Carbon Hydrogen Accelerator, which was announced in November. The six-month accelerator program offers collaboration and engagement opportunities with the Electric Power Research Institute and its member utilities, as well as with Shell. Through the accelerator, the institute and Shell will provide startups with two innovation paths: a technology validation track and a technology demonstration track.

The accelerator — part of the Green Go program, affiliated with Greentown Labs — is aimed at coming up with innovations in low-carbon hydrogen production, storage, and distribution.

“Accelerating low-carbon hydrogen technologies is an essential part of achieving global net-zero targets by 2050,” Neva Espinoza, vice president of energy supply and low-carbon resources at the Electric Power Research Institute, says in a news release.

The inaugural LCHA cohort includes:

  • Advanced Ionics, based in Milwaukee, is enabling green hydrogen production without the green premium.
  • Arco Technologies from Bologna, Italy, is developing a proprietary Anion Exchange Membrane electrolyzer with the lowest capital expenditures and operating expenses possible today.
  • Based in Manchester in the United Kingdom, Clean Power is developing a novel, low-cost, highly durable hydrogen polymer electrolyte membrane fuel cell delivering zero-emission electricity.
  • Element Resources, based in Houston, is enabling compressed hydrogen storage tank technology.
  • Another local company, Smartpipe Technologies is developing a robust self-monitored repurposed pipeline system for hydrogen with minimal environmental disruption.
  • SPEC Sensors from California is creating a robust and reliable meshed sensor network for hydrogen leak detection and line-monitoring systems.
  • Canadian company RUNWITHIT Synthetics is creating a live, digital twin modeling platform that generates decision-support data for regional hydrogen-demand scenarios.

Element Resources, which produces hydrogen from renewables for mobility, power production, and energy storage, is collaborating with Zhifeng Ren, M.D. Anderson chair professor in physics and director of the Texas Center for Superconductivity at the University of Houston.

The other Houston startup, Smartpipe Technologies, announced earlier this month that Canadian pipeline company Enbridge had made a $6.6 million investment in the startup.

For 2022, the accelerator received applications from 88 startups in 18 countries. The five other participants this year are from California; Wisconsin; Alberta, Canada; Italy; and the United Kingdom.

Aside from the Electric Power Research Institute, Shell USA, and Greentown, the accelerator’s partners are the City of Houston and the Urban Future Lab at New York University’s Tandon School of Engineering.

“Creating a robust hydrogen economy will require a systems-oriented approach and unparalleled cooperation between corporate partners and emerging companies,” says Ryan Dings, chief operating officer and general counsel at Greentown Labs.

Greentown operates startup incubators in Somerville, Massachusetts, and Houston.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”