Houston software entrepreneur discusses company growth and the importance of remembrance during Pride Month

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For Cody Gremminger, this month is about remembrance. Courtesy of Cyber One Solutions

One day, Cody Gremminger sat down with his fiance, Brian Carrico, and decided going into business together was something they wanted to explore. They put their heads together, thought of a name — Cyber One Solutions — and created a management, service and IT support company that serves the greater Houston area with satellite offices in Austin, Dallas, Lufkin, Brenham, and Beaumont.

Cyber One Solutions has experienced massive growth in less than two years of being in business, and InnovationMap sat down to talk with Gremminger about Cyber One's next steps, what it's like working with your partner, and the importance of the support gained by the LGBTQ community.

InnovationMap: Your company is less than two years old, but you’ve had massive growth and success. What are some lessons that you’ve learned throughout that time?

Cody Gremminger: We're an IT company, so definitely making sure that we have a huge book of processes and everything like that. Organization is one of the most important things. Finding good people that treat your clients that way that you treat them. Whenever you start off with a company and it's just the two founders, you know how you want to treat all of your clients. But it is hard to find people to treat the clients the same way you want to treat them.

IM: What do the next steps of Cyber One Solutions look like?

CG: The next steps of the company at this point are to keep growing and keep taking care of our current clients, just like every company in their infancy age.

IM: Are you planning on growing your team or slate of services anytime soon?

CG: We are looking into both. We have a couple of our team members working on getting further certifications and further training into new aspects of IT. We're also working on growing our current client base past what we already have.

We have some clients that we work with every month because we have a contract with them, and we have some clients that kind of come and go. On a monthly basis, we probably work with about 25 to 30 clients and then as far as people who need a hard drive replaced or something like that, it adds about 10 to 15 extra clients a month.

IM: You and Brian own the business together. What are some of the pros and cons of being a couple and working together?

CG: There's a lot of pros. It's really good because you are both fully committed. We're normally on the same page; we're always on the same team. We're both here for Cyber One Solutions. It kind of helps that this is how we pay our bills too.

We're very actively involved and dedicated to it. Some of the cons could be that work never quits. Once you get home, what are you going to talk about? Well, we've been working together all day so we're going to talk about work.

I suspect that other couples talk about their different jobs, while we talk about things we worked on at the same company. It is a different dynamic. My parents actually own a company together and work together too, so it's not abnormal for me, I guess.

IM: As members of the Greater Houston LGBTQ Chamber of Commerce, you’re connected with a wide variety of entrepreneurs in the LGBTQ community. Why is having that support system so important?

CG: We're members of the LGBT Houston chamber, and we're also recently, as of March or April, we got our National LGBT Chamber certification. The Houston LGBT Chamber is one of our favorites. It's just a place where we feel like everybody is actually there for each other. They are there to meet new businesses and talk to everybody. It's super friendly, and it's a place where you can just be yourself. It's awesome. I love going to all of their events.

IM: What does pride month mean to you?

CG: Pride month to me is all about celebration, awareness, and remembrance. At Pride, everybody is there and we are all celebrating the fact that we are who we are, and we're all celebrating each other. Awareness kind of goes with celebration.

We start to see corporate logos change color. For example, I took a photo of the HP float at Pride because we are HP partners here at Cyber One, and I do a lot with HP computers. It was cool to see them have a float in the parade. A couple of our vendors that we use, their logos turned rainbow. It's just been really cool.

I would say that remembrance because at pride, they give you a second to stop and look back and see how far this community has come. We've had the Pulse nightclub shooting…we've had Stonewall, which was a theme of the Pride parade this year. It's just all of that wrapped together.

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Portions of this interview have been edited.

Corey Allen had entrepreneurialism in his blood — but it wasn't until he got involved with the Greater Houston LGBT Chamber that he got the courage to break out on his own. Courtesy of Corey Allen

Houston entrepreneur explains how he's seen the city's LGBT and innovation communities evolve

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Corey Allen grew up surrounded by entrepreneurship. His family owned several small businesses when he was growing up. But it took the support of his community to push him toward leadership.

From working in an accounting firm to dabbling in a few oil and gas companies, Allen's career trajectory changed when he joined the Greater Houston LGBT Chamber of Commerce. Within the organization, for which he serves as treasurer, he met other motivated entrepreneurs and was given the support needed to open his own business, Ecotone.

Allen spoke with InnovationMap about his career and the importance of the LGBTQ community in entrepreneurship.

InnovationMap: How does Houston differ from other cities in the U.S. in terms of technology and entrepreneurship? What makes Houston different?

Corey Allen: I think everybody does default to Austin, right? People believe that that's the only technology hub in Texas. Houston is new and different from other cities in terms of tech and entrepreneurship, right now especially. In creating three local startups, we experienced tremendous support from well-established groups like the Greater Houston Partnership, the city of Houston with the Mayor's entrepreneurship program, the Greater Houston Chamber of Commerce. But, you know, what I think what is really new especially for Texas, within in Houston, is the local coworking spaces that are globally recognized brands and the coding camps. I think that is what is creating the infrastructure and ecosystem that we've been talking about for the last five years at least. I think that compared to other cities in the U.S., I don't see that type of energy and that type of investment being created in Houston right now.

IM: You mentioned a little bit about being involved in the process of creating three local startups. What makes Houston the right place to be involved in the startup culture that’s cultivating right now?

CA: I think there's two things that come to mind. Houston really is home, and it's always been home for me. And it really is a big, small town. I came from a small town in Texas, about halfway between Houston and Dallas, and our family always navigated to Houston for fun, but also for business. It was really the foundation for my own family, and I think what we get out of Houston is that southern hospitality is a real thing. So, that's certainly the first thing. And the second is that Houston has the foundation for a prosperous ecosystem. Obviously, there's a lot of oil and gas and the Texas Medical Center is already globally recognized. The more that we continue to focus on venture capital and innovation, which is what is wanted and needed right now, Houston is creating our own new technology and entrepreneurship to capture everybody's attention.

IM: What are some of the ways the tech and innovation community support their LGBTQ colleagues throughout the month of June?

Yeah, I love this question. I think it goes without saying for the community to come out and support the LGBTQ community by joining the chamber of commerce. Also, attending our second annual Pride in Business, which is June 28. That's been an outstanding event for all of the businesses in the community to be involved in the LGBT community. In three years time, (the Greater Houston LGBT Chamber) has been growing exponentially to over 125 visible members. And we have corporate partnerships that really speak to the impact that is being made in the community and in Houston. We have corporate partners like Shell and United. And also celebrate and attend the Houston Pride Parade, which is on June 22.

IM: What advice do you have for up-and-coming lgbtq entrepreneurs?

CA: The learning is the action. I used to really be annoyed by the phrase "sell faster." I actually live that now. You can't fail until you act, and now I know that you can't compete until you fail.

IM: That's great advice right there. What does pride month mean to you?

CA: It's very personal, and it hits home. My partner and I are going to be celebrating 19 years together in September, and I think that pride means celebrating a history that we don't stop to think about everyday. We were at a chamber meeting recently, and a member was sharing her experience of walking in the second pride parade. And she said that it wasn't the same. Even the police at the time did not protect the community. And that's a big difference from today. And I think anybody that goes out to the pride parade this year, I want them to know they're safe. And you know, I think that that's what we have to be thankful for today is to know that we can love without constant fear. It really just reminds us that we're not going to let anyone take that away again.

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Portions of this interview have been edited.

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New Houston biotech co. developing capsules for hard-to-treat tumors

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Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

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The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

Microsoft partners with Rice University's OpenStax on AI teaching tool

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Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”

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