Natalie Goodman founded Incentifind, which connects home builders and commercial developers with green incentives. Courtesy of Incentifind

When asked about the origin story of IncentiFind — a Houston-based startup that connects real estate developers and home builders with green construction incentives — founder Natalie Goodman doesn't mince words.

"We're a complete accident," Goodman says. "I'm an architect. We didn't set out to have a startup."

IncentiFind's mission is to increase the amount of green developments and construction projects in the U.S. The company is equipped with a massive database of green incentives that are offered by utility, county, city, state and federal agencies. Many home builders or commercial developers don't take advantage of green incentives because they're simply not aware of them, Goodman says.

"The government is strapped — they have all this money that they want to give away, but not the (marketing) money to get the word out," Goodman said. "That's where IncentiFind stepped in."

Goodman said IncentiFind's goals differ slightly for commercial and residential developers. For commercial developers, the database is built to be simple, predictable and intuitive. For home builders, the model is to make IncentiFind as simple and inexpensive as possible, since new homeowners are already shelling out cash for home improvement projects.

Commercial developers can expect to spend around $1,500 with IncentiFind, while homeowners can expect to spend between $50 and $150.

By tapping into IncentiFind's resources, Goodman says that clients can expect up to a tenfold increase on their investment with IncentiFind — all while developing in an environmentally conscious way.

An 'overnight' surge in demand
Goodman started building the infrastructure for IncentiFind several years ago, and long before she thought she'd one day be running a startup. She was a sustainability architect, living overseas and seeing that green architecture was far more common around the world than it was in the U.S.

Once she returned to the U.S., Goodman called a good friend at the Department of Energy, and asked where she could find a central database for green construction incentives in the U.S. She was told that a central database didn't exist, and probably never would.

"So, I created it selfishly just for me," Goodman says. "I thought [that I was] going to have this tiny little architecture firm, and we're going to do all things green."

At that time, several outdated incentive databases were still funded by public agencies. But at the end of 2017, a massive defunding of databases meant that Goodman's resource was the only one of its kind in the U.S.

Following the defunding of those databases, Goodman saw a surge of activity to her website from people who used to rely on those databases as go-to resources.

"Overnight, we saw that traffic come to us," Goodman says. "We didn't do any marketing — it was all organic. People were desperate to find this information. We weren't high on Google."

From Houston, to Austin, to Houston again
From there, Goodman decided to take her database to the next level. Six employees were hired, and in April 2018, IncentiFind officially launched in Austin in The Capital Factory, a major startup incubator. Goodman and the IncentiFind team were commuting from Houston. She wanted to launch the business in Houston, she said, and while there were a lot of exciting developments underway at Station Houston, Houston's startup scene was still clouded with uncertainty.

"There's already so much instability with a startup, and we can't surround ourselves with more instability," Goodman said.

IncentiFind graduated from The Capital Factory's startup accelerator in August 2018. From there, IncentiFind landed at The Cannon, and is continuing to grow in Cannon Ventures. In less than twelve months, Goodman said she's seen Houston's startup scene undergo a nearly 180-degree shift, in large part due to the growth of The Cannon.

"I truly think that they're going to put Houston on the map for a radically new service, because they'll actually roll up their sleeves and do work with you," Goodman said. "[They'll do more] than just send you links or give you 15 minutes to ask someone a question. They'll give you all the time in the world, and [give] as many hours as you want."

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.