Cindy Taff of Sage Geosystems shares her vision for her company and for the future of energy. Photo courtesy of Sage

When Cindy Taff was a vice president at the giant oil and gas company Shell in Houston, her middle schooler Brianna would sometimes look over her shoulder as she worked from home.

“Why are you still working in oil and gas?” her daughter asked more than once. “Is there a future in it? Why aren’t you moving into something clean?”

The words weighed on Taff.

“As a parent you want to give direction, and was I giving her the right direction?” she recalled.

At Shell, Taff was in charge of drilling wells and bringing them into production. She worked on oil and natural gas that's called unconventional in the industry, because the oil or natural gas is difficult to get out of the ground — it doesn't naturally gush out like in movies. It's a term often used for oily shale rock. Taff was somewhat unconventional for the industry, too. Her coworkers used to tease her for driving an efficient hybrid.

“You’re not helping oil and gas prices by driving a Prius," they'd say.

______

EDITOR’S NOTE: This is part of an occasional series of personal stories from the energy transition — the change away from a fossil-fuel based world that largely causes climate change.

______

Taff wanted Shell to pursue the energy that comes from the Earth's natural heat — geothermal. Her team looked into it, but Shell never greenlit any of those projects, saying it would take too much time to recoup the investment.

When Brianna went to college, she was passionate about energy too, but she wanted to work on renewables. After her sophomore year, in the summer of 2020, she got an internship at a geothermal company — one that in fact had just been launched by Taff's former colleagues at Shell — Sage Geosystems in Houston.

Now it was Taff looking over her daughter's shoulder and asking question as she worked from home during the pandemic.

And Sage executives were talking to Brianna, too. “We could use your mom here," they said. "Can you get her to come work for us?” Brianna recalled recently.

That's how Cindy Taff left her 36-year career at Shell to become chief operating officer at Sage.

“I didn't understand why Shell wasn't pursuing it,” she said about applying the company's drilling expertise to heat energy. "Then I got this great opportunity to pivot from oil and gas and work with these guys that I have the utmost respect for. And also, I wanted to make my daughter proud, quite frankly.”

Brianna Byrd, now 24, is the operations engineer and spokesperson at the company. She's glad her mother, now CEO, left oil and gas.

“Of course I’m biased, she’s my mom, but I don’t think Sage would be where it is without her,” she said.

The United States is a world leader in electricity made from geothermal energy, but this kind of electricity still accounts for less than half a percent of the nation’s total large-scale generation, according to the U.S. Energy Information Administration. In 2023, most geothermal electricity came from California, Nevada, Utah, Hawaii, Oregon, Idaho and New Mexico, where there are reservoirs of steam, or very hot water, close to the surface.

The Energy Department estimates this next generation of geothermal projects, like what Sage is doing, could provide some 90 gigawatts by 2050 — enough to power 65 million homes or more. That hinges on private investment, and on companies like Sage introducing this form of energy to regions where, until now, it’s been thought to be impossible.

How it works

Sage has two main technologies: The first makes electricity out of heat. The company drills wells and fractures hot, dry rock. Then electric pumps push water into those fractures, heating it up, and the hot water gets jettisoned to the surface where it spins a turbine.

But a funny thing happened during testing in Starr County, Texas. In late 2021, the team realized much of their technology could also be used to store energy.

If that works, it could be a big deal. Currently, to store energy at large scale, the United States is adding batteries, mostly lithium-ion type, to solar and wind projects, so they can charge up and send electricity back to the electric grid when the sun is not shining or the wind is not blowing. These batteries typically supply four hours maximum power.

Sage envisions some of its technology placed at solar and wind farms, too. When electricity demand is low, they'll use extra energy from a solar or wind farm to run electric pumps, pumping water into the underground fractures, leaving it there until demand for electricity increases — storing the energy beneath the Earth's surface for hours, days or even weeks.

It's a novel way to use the technology, said Silviu Livescu, lead author on a report looking at the future of geothermal in Texas. Livescu knows Taff and has followed the company's progress.

“It’s the right moment for companies like Sage with a purpose, with a mission and with the technology to show that geothermal indeed is the energy source we need to address climate change,” said Livescu, who co-founded a different geothermal startup in Austin, Texas.

These days, Taff is often out in front, talking with politicians and policymakers about the potential of geothermal. She attended the United Nations COP28 climate talks last year to share her vision for this kind of energy.

Sage has raised $30 million so far and is growing.

It's building a small (3-megawatt), geothermal energy storage system at San Miguel Electric Cooperative, Inc., south of San Antonio this year. It's working with U.S. military facilities in Texas that see geothermal as a way to power their bases securely. Sage recently announced partnerships for heating communities in Bucharest, Romania; clean electricity from geothermal for Meta's data centers, and energy storage and geothermal projects in California.

The company is final-testing a proprietary turbine to more efficiently convert heat to electricity.

Because of her oil and gas background, Taff said she knows geothermal will only be adopted widely if the cost comes down. The mantra at Sage is: It's going to be clean and it's going to be cheap. She's excited to be working in a field she feels is on the cusp of playing a big role in cleaning and stabilizing the electrical grid.

“I’ve never looked back,” she said. “I love what I’m doing and I think it’s going to be transformative.”

A new program at Rice University will educate recent graduates or returning learners on key opportunities within energy transition. Photo via Rice.edu

New program to produce innovative, sustainability-focused workforce for energy industry

coming this fall

A Houston university has committed to preparing the workforce for the future of energy with its newest program.

Rice University announced plans to launch the Master of Energy Transition and Sustainability, or METS, in the fall. The 31 credit-hour program, which is a joint initiative between Rice's George R. Brown School of Engineering and the Wiess School of Natural Sciences, "will train graduates to face emergent challenges in the energy sector and drive innovation in sustainability across a wide range of domains from technology to economics and policy," according to the university.

“We believe that METS graduates will emerge as leaders and innovators in the energy industry, equipped with the skills and knowledge to drive sustainable solutions,” Rice President Reginald DesRoches says in the release. “Together we can shape a brighter, more resilient and cleaner future for generations to come.”

Some of the focus points of the program will be geothermal, hydrogen, and critical minerals recovery. Additionally, there will be education around new technologies within traditional oil and gas industry, like carbon capture and sequestration and subsurface storage.

“We are excited to welcome the inaugural cohort of METS students in the fall of 2024,” Thomas Killian, dean of the Wiess School of Natural Sciences and a professor of physics and astronomy, says in the release. “This program offers a unique opportunity for students to delve into cutting-edge research, tackle real-world challenges and make a meaningful impact on the future of energy.”

The new initiative is just the latest stage in Rice's relationship with the energy industry.

“This is an important initiative for Rice that is very much aligned with the university’s long-term commitment to tackle urgent generational challenges, not only in terms of research — we are well positioned to make significant contributions on that front — but also in terms of education,” says Michael Wong, the Tina and Sunit Patel Professor in Molecular Nanotechnology, chair and professor of chemical and biomolecular engineering and a professor of chemistry, materials science and nanotechnology and of civil and environmental engineering. “We want prospective students to know that they can confidently learn the concepts and tools they need to thrive as sustainability and energy transition experts and thought leaders.”

------

This article originally ran on EnergyCapital.

Tim Latimer, CEO and co-founder of Fervo Energy, is seeing success at his company's Utah geothermal site. Photo via LinkedIn

Houston energy startup reports 'dramatic acceleration' of drilling operations at geothermal project

big win

Early drilling results indicate a geothermal energy project operated in Utah by Houston-based startup Fervo Energy is performing better than expected.

Fervo says its drilling operations Utah’s Cape Station show a 70 percent reduction in drilling times, paving the way for advancement of its geothermal energy system. Fervo began construction last year on Cape Station, which is set to deliver clean power to the grid in 2026 and be fully operating by 2028.

The company recently published early drilling results from Cape Station that it says exceed the U.S. Department of Energy’s expectations for enhanced geothermal systems. Fervo says these results “substantiate the rapid learning underway in the geothermal industry and signal readiness for continued commercialization.”

Founded in 2017, Fervo provides carbon-free energy through development of next-generation geothermal power.

Fervo began drilling at Cape Station, a 400-megawatt project in southwest Utah, in June 2023. Over the past six months, the company has drilled one vertical well and six horizontal wells there. The company reports that costs for the first four horizontal wells at Cape Station fell from $9.4 million to $4.8 million per well.

“Since its inception, Fervo has looked to bring a manufacturing mentality to enhanced geothermal development, building a highly repeatable drilling process that allows for continuous improvement and, as a result, lower costs,” Tim Latimer, Fervo’s co-founder and CEO, says in a news release. “In just six months, we have proven that our technology solutions have led to a dramatic acceleration in forecasted drilling performance.”

Trey Lowe, chief technology officer of Oklahoma City-based oil and gas producer Devon Energy, likens Fervo’s drilling results to “the early days of the shale revolution.” Last year, Devon invested $10 million in Fervo.

“When you operate continually and understand the resource, you dramatically streamline operations. That’s the unique value of Fervo’s approach to enhanced geothermal,” says Lowe.

Last summer, Fervo reported the results of another one of its projects, Project Red, which is in northern Nevada and made possible through a 2021 partnership with Google. That site officially went online for the tech company in December.

------

This article originally ran on EnergyCapital.

Houston-based Sage Geosystems announced the first close of $17 million round led by Chesapeake Energy Corp. Photo via sagegeosystems.com

Houston energy startup closes $17M series A to fund Texas geothermal facility

money moves

A Houston geothermal startup has announced the close of its series A round of funding.

Houston-based Sage Geosystems announced the first close of $17 million round led by Chesapeake Energy Corp. The proceeds aim to fund its first commercial geopressured geothermal system facility, which will be built in Texas in Q4 of 2024. According to the company, the facility will be the first of its kind.

The venture is joined by technology investor Arch Meredith, Helium-3 Ventures and will include support from existing investors Virya, LLC, Nabors Industries Ltd., and Ignis Energy Inc.

“The first close of our Series A funding and our commercial facility are significant milestones in our mission to make geopressured geothermal system technologies a reality,” Cindy Taff, CEO of Sage Geosystems, says in a news release. “The success of our GGS technologies is not only critical to Sage Geosystems becoming post-revenue, but it is an essential step in accelerating the development of this proprietary geothermal baseload approach.

"This progress would not be possible without the ongoing support from our existing investors, and we look forward to continuing this work with our new investors," she continues.

The 3-megawatt commercial facility will be called EarthStore and will use Sage’s technology that harvests energy from pressurized water from underground. The facility will be able to store energy — for short and long periods of time — and can be paired with intermittent renewable energy sources like wind and solar. It will also be able to provide baseload, dispatchable power, and inertia to the electric grid.

In 2023, Sage Geosystems debuted the EarthStore system in a full-scale commercial pilot project in Texas. The pilot produced 200 kilowatt for more than 18 hours, 1 megawatt for 30 minutes, and generated electricity with Pelton turbines. The system had a water loss of less than 2 percent and a round-trip efficiency (RTE) of 70-75.

Cindy Taff of Sage Geosystems explains why she's so optimistic about geothermal and her company's technology. Photo courtesy of Sage

Houston sustainability startup founder on why geothermal is a 'cornerstone' tech for energy transition

Q&A

Geothermal energy is an integral part of decarbonizing the energy industry, and Sage Geosystems CEO Cindy Taff believes her company's tech has what it takes to lead the way.

Founded in Houston in 2020, Sage Geosystems is focused on two business lines — energy storage and geothermal. In addition to developing these technologies, Taff says Sage has "cracked the code" on both reducing costs and maximizing electricity output. Sage has customers ranging from Nabors, the world’s largest land-based drilling company, and Virya LLC, an investor in climate ventures with high impact of eliminating global greenhouse gas emissions or sequestering CO2

In a Q&A that originally ran on EnergyCapital, she explains why she's so optimistic about geothermal and her company's technology.

EnergyCapital: Why do you believe geothermal has a major role to play in the energy transition?

Cindy Taff: Geothermal energy is not just a contender in the energy transition; it is a cornerstone. The question isn’t if we can drive down the costs to be competitive with wind, solar, and natural gas—it’s when. As renewable credits for solar and wind begin to expire, these industries will face the reality of their “real costs.”

As a 24/7 renewable energy source, it provides a constant and reliable power supply, unlike the intermittent nature of solar and wind. Moreover, the rising costs of lithium-ion batteries, driven by the increasing scarcity of lithium and cobalt, further underscore geothermal’s economic viability.

My extensive experience in both geothermal and the O&G sector is a testament to the synergistic relationship between these industries. The skills honed in O&G are not only transferable—they are essential to advancing geothermal technologies. In summary, the O&G industry can make a huge impact to geothermal by systematically driving down costs while scaling up, which is exactly what we did for unconventional shales.

EC: When it comes to finding partners or investors, what are you looking for? What should potential partners/investors know about Sage?

CT: Our technology is ready to scale today, not five to 10 years into the future. We will deliver our first energy storage power plant in 2024 and our first enhanced geothermal power plant in 2025. We are looking for synergies with investors, such as companies with power market or O&G expertise.

In addition, we seek to partner with others who have local content and relationships in places around the world to enable us to quickly and broadly scale our technologies. Sage's technologies are extremely flexible, in that we can deliver energy storage or enhanced geothermal to the utility grid or behind-the-meter to targeted commercial customers, including a dedicated microgrid (i.e., for the U.S. Air Force). Our technologies can provide electricity to remote locations such as mining operations or to large population centers such as Houston, and everything in between.

EC: What's the biggest challenge Sage is facing as an energy transition startup and how do you plan to tackle it?

CT: A common misunderstanding about Sage is that we only do energy storage or that we only do geothermal. However, we do both and the technologies build on one another. Essentially, our energy storage technologies will allow us to "walk" before we "run" with geothermal. On a related point, at this point in the energy transition, time to commercialization and affordability of new clean technology are the leading factors in terms of climate impact. As the first geothermal company to deliver a cost-effective commercial enhanced geothermal system, we are poised to truly make a meaningful difference.

EC: As a woman in a male-dominated industry tackling a global problem, what's been your biggest lesson learned? What's your advice to fellow energy tech female founders?

CT: In my journey as a woman in the energy tech industry, I’ve been fortunate to focus on the work and the global challenges we’re addressing, rather than on any gender-based obstacles. My biggest lesson learned is that innovation and leadership know no gender. Success is driven by perseverance, vision, and collaboration.

------

This conversation has been edited for brevity and clarity.

Fervo Energy's Project Red with Google is officially operational. Photo via blog.google

Houston startup's sustainable energy project with Google goes online

switch flipped

Google is on a mission to run all of its data centers and office campuses on constant carbon-free energy by 2030, and the tech giant is one step closer to that goal.

Last week, Google announced that its 24/7 carbon-free energy, or CFE, in Nevada to power its local data center in the state is officially operational. The facility is powered by Houston-based Fervo Energy's geothermal technology, a project — called Project Red — that began in 2021 and celebrated its successful pilot this summer.

"When we began our partnership with Fervo, we knew that a first-of-a-kind project like this would require a wide range of technical and operational innovations," Michael Terrell, senior director of energy and climate at Google, writes in a blog post about the partnership.

Fervo relies on tried and true drilling techniques from the oil and gas industry, accessing heat energy that previously has been elusive to traditional geothermal methods, Terrell continues. Fervo dug two horizontal wells at the Nevada plant, as well as installed fiber-optic cables to capture data that tracks performance and other key information.

"The result is a geothermal plant that can produce round-the-clock CFE using less land than other clean energy sources and drawing on skills, knowledge, and supply chains that exist in other industries," Terrell says. "From our early commitment to support the project’s development to its successful completion, we’ve worked closely with Fervo to overcome obstacles and prove that this technology can work."

Google also recently announced a partnership with Project InnerSpace, a nonprofit focused on global geothermal energy development.

Fervo is working on another nearby project, the company announced in September. The 400-milliwatt geothermal energy project in Cape Station, Utah, will start delivering carbon-free power to the grid in 2026, with full-scale production beginning in 2028.

The project, in southwest Utah, is about 240 miles southwest of Salt Lake City and about 240 miles northeast of Las Vegas. Cape Station is adjacent to the U.S. Department of Energy’s Frontier Observatory for Research in Geothermal Energy (FORGE) and near the Blundell geothermal power plant.

------

This article originally ran on EnergyCapital.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Tesla no longer world's biggest EV maker as sales fall for second year

Tesla Talk

Tesla lost its crown as the world’s bestselling electric vehicle maker as a customer revolt over Elon Musk’s right-wing politics, expiring U.S. tax breaks for buyers and stiff overseas competition pushed sales down for a second year in a row.

Tesla said that it delivered 1.64 million vehicles in 2025, down 9% from a year earlier.

Chinese rival BYD, which sold 2.26 million vehicles last year, is now the biggest EV maker.

It's a stunning reversal for a car company whose rise once seemed unstoppable as it overtook traditional automakers with far more resources and helped make Musk the world's richest man. The sales drop came despite President Donald Trump's marketing effort early last year when he called a press conference to praise Musk as a “patriot” in front of Teslas lined up on the White House driveway, then announced he would be buying one, bucking presidential precedent to not endorse private company products.

For the fourth quarter, Tesla sales totaled 418,227, falling short of even the much reduced 440,000 target that analysts recently polled by FactSet had expected. Sales were hit hard by the expiration of a $7,500 tax credit for electric vehicle purchases that was phased out by the Trump administration at the end of September.

Tesla stock fell 2.6% to $438.07 on Friday.

Even with multiple issues buffeting the company, investors are betting that Tesla CEO Musk can deliver on his ambitions to make Tesla a leader in robotaxi services and get consumers to embrace humanoid robots that can perform basic tasks in homes and offices. Reflecting that optimism, the stock finished 2025 with a gain of approximately 11%.

The latest quarter was the first with sales of stripped-down versions of the Model Y and Model 3 that Musk unveiled in early October as part of an effort to revive sales. The new Model Y costs just under $40,000 while customers can buy the cheaper Model 3 for under $37,000. Those versions are expected to help Tesla compete with Chinese models in Europe and Asia.

For fourth-quarter earnings coming out in late January, analysts are expecting the company to post a 3% drop in sales and a nearly 40% drop in earnings per share, according to FactSet. Analysts expect the downward trend in sales and profits to eventually reverse itself as 2026 rolls along.

Musk said earlier last year that a “major rebound” in sales was underway, but investors were unruffled when that didn't pan out, choosing instead to focus on Musk's pivot to different parts of business. He has has been saying the future of the company lies with its driverless robotaxis service, its energy storage business and building robots for the home and factory — and much less with car sales.

Tesla started rolling out its robotaxi service in Austin in June, first with safety monitors in the cars to take over in case of trouble, then testing without them. The company hopes to roll out the service in several cities this year.

To do that successfully, it needs to take on rival Waymo, which has been operating autonomous taxis for years and has far more customers. It also will also have to contend with regulatory challenges. The company is under several federal safety investigations and other probes. In California, Tesla is at risk of temporarily losing its license to sell cars in the state after a judge there ruled it had misled customers about their safety.

“Regulatory is going to be a big issue,” said Wedbush Securities analyst Dan Ives, a well-known bull on the stock. “We're dealing with people's lives.”

Still, Ives said he expects Tesla's autonomous offerings will soon overcome any setbacks.

Musk has said he hopes software updates to his cars will enable hundreds of thousands of Tesla vehicles to operate autonomously with zero human intervention by the end of this year. The company is also planning to begin production of its AI-powered Cybercab with no steering wheel or pedals in 2026.

To keep Musk focused on the company, Tesla’s directors awarded Musk a potentially enormous new pay package that shareholders backed at the annual meeting in November.

Musk scored another huge windfall two weeks ago when the Delaware Supreme Court reversed a decision that deprived him of a $55 billion pay package that Tesla doled out in 2018.

Musk could become the world's first trillionaire later this year when he sells shares of his rocket company SpaceX to the public for the first time in what analysts expect would be a blockbuster initial public offering.

8+ can't-miss Houston business and innovation events in January

where to be

Editor's note: Kick off 2026 by hearing insightful talks and making meaningful connections in Houston's innovation scene. From networking workshops to presentations from major industry leaders, here's what not to miss and how to register. Please note: this article may be updated to include additional event listings.

Jan. 13 – Financing the Future

Hear from James Blake, head of capital markets at Fervo Energy, in this informative talk. Blake will cover the current investment landscape for geothermal power, how geothermal projects are structured and the role of policy incentives and innovative financing models in moving the industry forward. A small reception follows.

This event is Tuesday, Jan. 13, from 5:30-7:30 p.m. at the Ion. Register here.

Jan. 13 – Your Path to the Boardroom

Visit Sesh Coworking to hear from Keith Dorsey, an executive advisor and author of The Boardroom Journey, as he shares insights and lessons from hundreds of corporate board members and presents an actionable roadmap for women at every stage of their careers. Dorsey will speak on what "optimal diversity” means in the boardroom, how purpose-driven leaders sustain resilience under relentless pressure and why inclusive leadership is non-negotiable for growth and innovation.

This event is Tuesday, Jan. 13, from 6-8 p.m. at Sesh Coworking. Register here.

Jan. 14 — A Conversation with Dr. Wayne J. Riley on Leading Through Healthcare Transformation

Rice Business Partners will host Dr. Wayne J. Riley, president of SUNY Downstate Health Sciences University, for a moderated discussion with Dean Peter Rodriguez. Riley will share insights on leading complex healthcare organizations in an era of unprecedented industry challenges and reflect on his time at the Jones Graduate School of Business.

This event is Wednesday, Jan. 14, from 6:30-8:30 p.m. at McNair Hall on Rice University's campus. Register here.

Jan. 14 — VDW: Igniting Connections for Startup Success

Entrepreneurial communications instructor Diana Massaro will lead Lilie's latest Venture Development Workshop, focused on soft skills like clear communication, active listening and compelling introductions. Attendees will gain a personalized networking game plan and communication tools to turn casual encounters into meaningful relationships to support their ventures or careers.

This event is Wednesday, Jan. 14, from 6-7:30 p.m. at the Liu Idea Lab for Innovation and Entrepreneurship on Rice University's campus. Register here.

Jan. 21 — Upstream: Digital Tech Meetup

This month's Upstream: Digital Tech Meetup will explore how AI and real-time monitoring are being applied in safety-critical offshore environments, what’s working today, where the biggest gaps remain going into 2026 and how operators and service companies are approaching adoption. Expect to hear from leaders at NOV, Incom Solutions, Timbergrove and others.

This event is Wednesday, Jan. 21, from 8:30-10:30 a.m. at the Ion. Find more information here.

Jan. 22 — HEAD AND HEART: Leading Technology with Humanity While Everything Changes

Hear from Chris Hyams, former CEO of Indeed, at the latest installment of Rice's Master of Engineering Management & Leadership Seminar Series. Hyams will present on the intersection of technology, humanity and change—and how AI is reshaping all three.

This event is Thursday, Jan. 22, at 6 p.m. at Duncan Hall on Rice University's campus. Find more information here.

Jan. 22 – NASA Tech Talk

This month's NASA Tech Talks will feature a special delegation from the UK Science and Technology Network. Expect to hear from a panel of UK space experts, followed by a fireside chat featuring David Alexander, head of the Rice Space Institute, and Meganne Christian, ESA reserve astronaut and senior exploration manager.

This event is Thursday, Jan. 22, from 6-7 p.m. at the Ion. Find more information here.

Jan. 29 – Ignition Hub Startup Career Fair

Lilie will host the Ignition Hub Startup Career Fair this month in partnership with Rice University’s Center for Career Development and Career Development Office. The fair will bring together some of the most innovative, high-growth companies to offer Rice students exciting opportunities. Startups can apply to be considered for the fair. The event is open to Rice University undergraduate, graduate, MBA, and PhD students.

This event is Thursday, Jan. 29, at Grand Hall on Rice University's campus. Find more information here.

Jan. 29 – Health Policy Symposium: Value-Based Care & the Health Care Workforce

The Humana Integrated Health Systems Science Institute at the University of Houston will host its latest Health Policy Symposium this month, focused on the evolving landscape of value-based care and the importance of preparing and strengthening the health care workforce. Hear keynote addresses from leaders at Humana, UH, the American Medical Association and Houston Health Department.

This event is Thursday, Jan. 29, from 11:30 a.m.-1:30 p.m. at the Tilman J. Fertitta Family College of Medicine on Rice University's campus. Find more information here.

Jan. 30 — GHP Annual Meeting

The Greater Houston Partnership's premier event will highlight the region’s progress, honor visionary leadership and set the tone for the year ahead. Hear reflections from outgoing board chair, Gretchen Watkins (former -president of Shell USA); welcome incoming board chair, Armando Perez (EVP of H-E-B Houston); and more

This event is Friday, Jan. 30, from 11:30 a.m.-1:30 p.m. at Hilton Americas. Find more information here.

CPRIT CEO: Houston’s $2B in funding is transforming cancer research and prevention

fighting cancer

With its plethora of prestigious health care organizations like the University of Texas MD Anderson Cancer Center, UTHealth Houston, and the Baylor College of Medicine, Houston sits at the heart of cancer research and prevention in Texas.

Of course, it takes piles of cash to support Houston’s status as the state’s hub for cancer research and prevention. Much of that money comes from the Cancer Prevention and Research Institute of Texas (CPRIT).

Data supplied by CPRIT shows organizations in Harris County gained $2.3 billion in institute funding from 2009 through 2025, or nearly $145 million per year. That represents almost 60 percent of the roughly $4 billion that CPRIT has granted to Texas institutions over a 16-year period.

“The life sciences ecosystem that has developed and changed in Houston is phenomenal,” Kristen Doyle, who became the agency’s CEO in July 2024, tells InnovationMap. “In the next decade, we will look back and see a great transformation.”

That ecosystem includes more than 1,100 life sciences and biotech companies, according to the Greater Houston Partnership.

Houston plays critical role in clinical trials

Texas voters approved the creation of CPRIT in 2007. Twelve years later, voters agreed to earmark an extra $3 billion for CPRIT, bringing the state agency’s total investment in cancer research and prevention to $6 billion.

To date, CPRIT money has gone toward recruiting 344 cancer researchers to Texas (mainly to Houston) and has supported cancer prevention services for millions of Texans in the state’s 254 counties. CPRIT funding has also helped establish, expand, or relocate 25 cancer-focused companies. In Houston, MD Anderson ranks as the No. 1 recipient of CPRIT funding.

Regarding cancer research, Doyle says Houston plays a critical role in clinical trials.

“[Clinical trials are] something that CPRIT has focused on more and more. Brilliant discoveries are crucial to this whole equation of solving the cancer problem,” Doyle says. “But if those brilliant ideas stay in the labs, then we’ve all failed.”

Researchers conduct more clinical trials in Houston than anywhere else in the U.S., the Greater Houston Partnership says.

Doyle, a 20-year survivor of leukemia, notes that a minority of eligible patients participate in clinical trials for cancer treatments, “and that’s one of the reasons that it takes so long to get a promising drug to market.”

An estimated 7 percent of cancer patients sign up for clinical trials, according to a study published in 2024 in the Journal of Clinical Oncology.

MD Anderson takes on cancer prevention

Doyle also notes that Houston is leading the charge in cancer prevention.

“We get some national recognition for programs that have been developed in Houston that then can be replicated in other parts of the country,” she says.

Much of the work in Houston focusing on cancer prevention takes place at MD Anderson. The hospital reports that it has received more than $725 million from the CPRIT since 2007, representing approximately 18 percent of CPRIT’s total awards.

“These efforts can have profound impact on the lives of patients and their families, and this funding ensures our exemplary clinicians and scientists can continue working together to drive breakthroughs that advance our mission to end cancer,” Dr. Giulio Draetta, chief scientific officer at MD Anderson, said in a November news release, following the most recent CPRIT award for the hospital totaling more than $29 million.

CPRIT funding for Houston institutions supplements the more than $4.5 billion in federal funding for health and life sciences research and innovations that the Houston area received from 2020 to 2024, according to the Greater Houston Partnership.

“We are curing cancer every single day,” Doyle says of CPRIT. “Every step that we are taking — whether that’s funding great ideas or funding the clinical trials that are bringing promising drugs to Texas and to the world — we are making a difference.”