Photos: Houston innovation leaders weigh in on cybersecurity, tech, and more at inaugural event

total knock out

The Digital Fight Club made its Houston debut on November 20 at White Oak Music Hall. Emily Jaschke/InnovationMap

What do you get when you cross the information of an innovation panel with the ferocity of a boxing match? A verbal sprawling among innovation leaders that can only be known as the Digital Fight Club.

Houston's DFC came about with the help of Accenture, which had been a partner at the Dallas events, and InnovationMap, who teamed up as presenting sponsors for the event. DFC's founder, Michael Pratt, came up with the idea for Digital Fight Club as a way to liven up technology-focused events and networking opportunities.

The setup of the event is five fights, 10 fighters, and five judges. Each fighter has just a couple minutes to take their stand before the event moves on.

"This is Digital Fight Club," says Pratt, CEO of the company. "You get subject matter experts, and serious founders and CEOs on the stage and make them make their case. You learn something, it's a lot of fun, and it's a lot better than a panel."

The hour of fighting is coupled with a VIP event ahead of the showdown and an after party where further networking can continue on. At Houston's VIP event, InnovationMap got to check in with partners, fighters, and referees about how they thought the event was going to pan out. Check out the VIP event video here.

The panel of referees included Gabriella Rowe, CEO of Station Houston; Denise Hamilton, CEO of Watch Her Work; TimKopra, partner at Blue Bear Capital; Lance Black, Director at TMCx; and Barbara Burger, president of Chevron Technology Ventures.

The refs asked two questions per fight, and were able to vote on the winners of each round — as was the audience through an interactive web-based application. The break down of the fights, topics, and winners are as follows:

Fight #1: Future Workforce of Robotics/AI. Matt Hager, CEO of Poetic Systems, vs Pablo Marin, senior AI Leader, Microsoft. Hager took the win with 77 percent of the vote.
Fight #2: Whose responsibility is cybersecurity. Ted Gutierrez, CEO of SecurityGate vs Tara Khanna, managing director and Security Lead at Accenture. Khanna won this round, snagging 66 percent of the votes.
Fight #3: Oil & Gas Industry and the Environment. Michael Szafron - commercial adviser for Cemvita Factory, vs Steven Taylor, co-founder of AR for Everyone. Szafron received 76 percent of the voites, securing the win.
Fight #4: Digital in our personal lives. Grace Rodriguez, CEO of ImpactHub, vs Javier Fadul, chief innovation officer at HTX Labs. Rodriguez won with the largest margin of the night — 85 percent.
Fight #5: Future of Primary Care Geetinder Goyal, CEO of First Primary Care, vs Nick Desai, chief medical information officer at Houston Methodist. Goyal received 72 percent of the votes to take home the win.

The fights were heated, and some of the fighters had knockout quotes, from Hager's "AI is mostly bullshit" to Khanna's "Compliance doesn't mean you're secure." For more of the knockout quotes, click here.

The fight is on

  

Emily Jaschke/InnovationMap

Mike Pratt, who hosted the event, founded the Digital Fight Club in 2016.

Ten Houston innovators took the stage for five fights on the role technology plays in the future of industry. Emily Jaschke/InnovationMap

Overheard: Local fighters land knockout statements at Houston's first Digital Fight Club

Eavesdropping in houston

On Wednesday, Houston's innovation ecosystem hosted the rowdiest crowd at a professional business event that the city has ever seen.

Digital Fight Club, a Dallas-based event company, had its first Houston event at White Oak Music Hall on November 20 thanks to presenting sponsors Accenture and InnovationMap. The event featured 10 fighters and five referees across five fights that discussed cybersecurity, the future of primary care, and more.

"This is Digital Fight Club," says Michael Pratt, CEO of the company. "You get subject matter experts, and serious founders and CEOs on the stage and make them make their case. You learn something, it's a lot of fun, and it's a lot better than a panel."

If you missed the showdown, here are some of the nights zingers made by the entrepreneurs and subject matter experts that were the fighters of the evening.

"I believe that computers can get a lot of information to create [something new]. That's my job, that's what I do, and I see it done."

— Pablo Marin, senior AI leader at Microsoft, during the fight on robotics and AI in the workforce. Marin's argument was that artificial intelligence and robotics can and will replace all repetitive jobs. However, he also believes that computers have the ability to create, as well, based on their ability to see the whole world and have access to all the world's information.

"AI is mostly bullshit."

— Matthew Hager, CEO of Poetic Systems. Hager, who won the first fight of the night, responded to Marin that, while businesses like to believe that AI is actually able to deliver results so that they can sell more, the technology hasn't actually arrived yet. Plus, Hager says AI will never be creative without the human element. "Creativity is about who created it. It's about the photographer, not the camera," he says.

"What if the seatbelt laws and the speed limits were defined by Dodge, Ford, or Chrysler?"

— Ted Gutierrez, CEO and co-founder of Security Gate, who argued for government to take the reigns of cybersecurity. He adds that companies are never going to be able to agree to one set of rules. "We gotta get one group to set the standard, and it's up to everyone else to refine that and innovate for it," he says.

"Compliance doesn't mean you're secure."

— Tara Khanna, managing director and security lead at Accenture, who won the fight on cybersecurity needing to be figured out by the business industry. She argues that the private sector wins the war on talent and recruiting, so it has the money and resources to dedicate to the issue in more ways than the government ever will.

"I was born, I'm going to die, and there is nothing like earth in the universe as we know it. It is worth preserving and protecting."

— Steven Taylor, co-founder of AR for Everyone, in the fight over the oil and gas industry's responsibility to the environment. He argued that it's going to be a mix of policy and corporate initiatives that changes the industry.

"I think the free market is going to get there if the consumer has the choice to pick what they want to do."

— Michael Szafron, commercial adviser for Cemvita Factory, who took home the win for the oil and gas and the environment fight. Szafron's argument was that corporations are going to do what their consumers want, so that's who would drive them to action. "Let's look at California —very regulated environmentalists, and a million of those people get moved to Texas," he says.

"Disconnecting our personal lives from technology would not only limit ourselves, but it would also limit our capacity to adopt those tools to the needs of our society." 

— Javier Fadul, chief innovation officer at HTX Labs, during the fight on digital in our personal lives. Fadul argues that not only does technology allow us to connect worldwide, but disconnecting would prevent that technology from developing further.

"I love tech, but now that it's on all the time everywhere, we need to make time to unplug."

— Grace Rodriguez, CEO of Impact Hub Houston, who won the fight on personal technology. She says that yes, technology can help international connectivity, but it does more harm than good as people use personal tech as a default or distraction from humans right in front of them. "When your with people, be present," she says.

"Part of our innovation to redesign primary care is really to deploy technology out there to seamlessly provide care."

— Nick Desai, chief medical information officer at Houston Methodist, who argued that the future of primary care is new innovations within traditional medicine. He adds that virtual care, which is something Methodist is working on, can help improve accessibility.

"The future of primary care is here. It's called direct primary care." 

— Geetinder Goyal, CEO of First Primary Care, who won the fight on the future of primary care with his argument for a new, free market approach to medicine. Direct primary care opens up treatment and access to physicians with a monthly fee for patients to work outside of health care plans.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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