Comicpalooza takes place Friday, May 9, to Sunday, May 12. Courtesy of Comicpalooza

People from around the world will be flocking to downtown Houston by the thousands, and not just for the Astros and the Rockets. The 11th annual Comicpalooza is taking over the George R. Brown Convention Center from Friday, May 10, to Sunday, May 12.

"This major super block in downtown will be absolutely electric this weekend," Michael Heckman, Comicpalooza president, tells InnovationMap.

Last year, the convention attracted over 50,000 people from 47 states and 17 countries, and it made an economic impact of over $20 million, Heckman says. This year, with the help of Game of Thrones stars and an inaugural ESPN event, Comicpalooza should surpass last year's accomplishments.

Here's what you can expect from this weekend.

A crowd at the panel that has two Game of Thrones actresses

Emilia Clarke (left) plays Daenerys in Game of Thrones, and Nathalie Emmanuel plays her adviser and friend, Missandei. Photos courtesy of Comicpalooza

A panel on Saturday morning at 11 am will have two Game of Thrones stars — Emilia Clarke (Daenerys) and Nathalie Emmanuel (Missandei). The panel is sure to attract the masses, and the two actresses are major gets by the organization.

"To be able to get Emilia Clarke in the middle of the final season of Game of Thrones, with only two episodes to go — the hype has been unbelievable," Heckman says. "To be able to have a pop culture phenomenon like that come here to Houston — and it will be her first fan event. She's done the San Diego Comic Con, but that was more of a media event."

Both actresses also have autograph visits available for purchase. Clarke's are sold out online, but some opportunities will be made available day of.

The first ever ESPN collegiate esports competition

ESPN's inaugural esports competition for college students is premiering at Comicpalooza. Jamie McInall/Pexels

For the first time ever, ESPN is having a collegiate esports championship and chose Houston to be the place for the finals.

"We've understood the value of [esports] for Comicpalooza for a number of years. ESPN is making a big investment — it's their first ever event of this nature, but it won't be their last," Heckman says.

Students from hundreds of schools have competed to make it to the semifinals and championship in Houston, and scholarships are on the line. The weekend will have 22 teams across five video games — Hearthstone, Heroes of the Storm, Overwatch, StarCraft II, and Street Fighter V — according to ESPN. To read more about the competition, click here.

Makers on display

Anyone can check out the Comicpalooza Maker's Space — there's even a place to fix any cosplay wardrobe malfunctions. Photo via comicpalooza.com

Calling all makers — professionals or wannabes. Comicpalooza's Maker's Space is open to cosplayers, artists, engineers, scientists and everyone in between who wants to create and build using old and new technology, from small electrical parts to towering 3D printers and Lego masterpieces.

"What a lot of people don't know is there are so many interesting aspects to Comicpalooza — from literature tracks to a film festival to a makerspace," Heckman says. "There are hundreds of exhibitors on the expo showfloor, but there's an area carved out for makers."

A party on the promenade

Free concert anyone? Photo via comicpalooza.com

From 6 to 10 pm on Saturday, Avenida Houston will be transformed into an after party put on by Saint Arnold's and headlined by Icona Pop. It's free to attend, and you can get more info here.

VIPs all around

It's not just the Game of Thrones people being featured. Photos via comicpalooza.com

Comicpalooza attendees can grab photos with or autographs from over 30 different actors across major franchises — like Star Trek, Walking Dead, and so much more.

The list of actors is as follows: Emilia Clarke, Nathalie Emmanuel, Grant Gustin, Wilmer Valderrama, Dan Fogler, Gates McFadden, Michael Dorn, John Wesley Shipp, Peter Serafinowicz, Griffin Newman, Yara Martinez, Brendan Hines, Scott Speiser, Jeremy Davies, Andrew Divoff, Mira Furlan, Erick Avari and more.

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New TMC partnership aims to grow Houston’s biomanufacturing workforce

workforce partnership

Houston is a frontrunner in the race to introduce and manufacture advanced therapeutics to the medical world. A new agreement between the Texas Medical Center (TMC) and San Jacinto College (SJC) aims to speed more experts and their technologies towards the finish line.

Earlier this month, the world's largest medical center and the nation’s second-ranked community college announced their new partnership that will set students on a path towards careers not only in life sciences in general, but also in pharmaceutical and biomanufacturing specifically.

SJC already has programs in those majors—its first graduates are now joining the workforce—but working with TMC will help the college recruit new students, as well as aid in enrollment and participation. Thanks to this collaboration, SJC students will benefit from more experiential learning and be able to transition more smoothly into the next steps in their training.

“Houston is a premier global hub for life sciences and biotechnology, and the talent we need to advance therapeutic drugs, diagnostics, and cell and gene therapy is already here,” William McKeon, the TMC’s president and CEO, said in a news release. “With more companies choosing to establish their headquarters in Houston and the daily breakthroughs happening across the TMC campus, partnering with San Jacinto College is an important step toward sustaining that momentum and unlocking even greater innovation and growth through the promising talent that already exists within our state.”

The partnership is currently slated to last two years, but the institutions have the option to extend after that.

For students, their journey to becoming scientists will likely start with Biopath @ TMC, a program that introduces high school students to biomanufacturing careers and what it takes to pursue one. Since its inception two years ago, the program has worked with more than 2,000 students around Harris County.

“This partnership exemplifies San Jacinto College’s ability to design and deliver programs that align with current workforce demands while opening doors for untapped talent across the Houston region,” Brenda Hellyer, SJC chancellor, said in the release. “TMC is a key industry leader in our region, and San Jacinto College has a unique global curriculum that provides the foundation and skills required for students to succeed and graduates to thrive in meaningful careers that will contribute to the innovation and advancement of the life sciences.”

Thanks to this new collaboration, more of Houston’s biomanufacturing workforce will soon be locally grown.

Houston legacy planning platform secures $2.5M investment, adds to board

fresh funding

Houston-based Paige, a comprehensive life planning and succession software company, has secured a $2.5 million investment to expand the AI-driven tools on its platform.

The funding comes from Alabama-based 22nd State Banking Company, according to a news release. Paige says it will use the funding to expand automation, AI-driven onboarding and self-service tools, as well as add to its sales and customer success teams.

The company was originally founded by CEO Emily Cisek in 2020 as The Postage and rebranded to Paige last year. It helps users navigate and organize end-of-life planning with features like document storage and organization, password management, and funeral and last wishes planning.

“Too many families are left trying to piece together important information during some of the hardest moments of their lives,” Cisek said in the news release. “This investment allows us to accelerate the next phase of growth for Paige by improving the product and expanding support for our members, our financial institution partners and the communities they serve,”

In addition to the funding news, the company also announced that 22nd State Banking CEO and President Steve Smith will join Paige's board of directors.

“We believe banking should be grounded in relationships and built around the real needs of the people and communities we serve. Paige brings something deeply relevant to that mission," Smith added in the release. "It helps families prepare for the future in a practical and meaningful way, and it gives the banking community new pathways to support customers through important life transitions.”

Paige estimates that $124 trillion in assets will change hands through 2048. Yet about 56 percent of Americans do not have an estate plan.

Read more on the topic from Cisek in a recent op-ed here; or listen to InnovationMap's 2021 interview with her here.

Houston digital health platform Koda lands strategic investment

money moves

Houston-based advance care planning platform Koda Health has added another investor to the lineup.

The company secured a strategic investment for an undisclosed amount from UPMC Enterprises, the commercialization arm of the University of Pittsburgh Medical Center. The funding is part of Koda's oversubscribed series A funding round that closed in October, according to a release.

"UPMC Enterprises’ investment is a meaningful signal, not just to Koda, but to the broader market," Dr. Desh Mohan, chief medical officer and co-founder of Koda Health, said in the news release. "It validates that health systems are ready to invest in infrastructure that makes advance care planning work the way it should: proactively, at scale, and with the human support that these conversations require. Having UPMC Enterprises as a strategic investor puts us in a unique position to prove what's possible."

Koda has raised $14 million to date, according to a representative from the company. Its series A round was led by Evidenced, with participation from Mudita Venture Partners, Techstars and the Texas Medical Center last year. At the time, the company said the funding would allow it to scale operations and expand engineering, clinical strategy and customer success. The company described the round as a "pivotal moment," as it had secured investments from influential leaders in the healthcare and venture capital space.

Koda Health, which was born out of the TMC's Biodesign Fellowship in 2020, saw major growth last year, as well, and now supports more than 1 million patients nationwide through partnerships with Cigna Healthcare, Privia Health, Guidehealth, Sentara, UPMC and Memorial Hermann Health System.

The company integrated its end-of-life care planning platform with Dallas-based Guidehealth in April 2025 and with Epic Systems in July 2025. It also won the 2025 Houston Innovation Award in the Health Tech Business category. Read more here.