An expert from the U.S. Small Business Administration shares in an op-ed how critical women-owned businesses are to small business exports in Texas. Photo via Getty Images

Everything is bigger in Texas, including its small business ecosystem. There are over three million small businesses in the state, which represent 99.8 percent of all Texas businesses. However, according to the latest official U.S. Census Bureau data on small business exporters (2020), only 35,124 Texas-based companies exported goods abroad.

During my time in the Administration, I have had the opportunity to visit Texas on several occasions, including trips to Houston, San Antonio, and El Paso. Like most everything in Texas, the entrepreneurial ecosystem is sizable and a rich source of opportunity and ideas. But with over a thousand miles of shared border with Mexico, and considerable trade infrastructure like the Port of Houston, you can’t tell me that just 1 percent of Texas small businesses are exporting their products or services. This data, which mirrors the published trend for small business exporters nationwide, seemed severely undercounted. So, we endeavored to dig into what was going on.

As a result, the Office of International Trade (OIT) commissioned a study to determine the total addressable market (TAM) of small business exporters. The research dug deep into available public data and private surveys, which better accounted for smaller shipment values and growth in service exports. Among the key findings from the study is new data that places the actual number of exporting small businesses at 1.3 million – an almost fivefold increase over the estimates previously published by the Federal Government. Interestingly, minority, women-owned firms were found to over-index in selling abroad. The research also revealed a high concentration of certain tradeable sectors ranging from consumer, industrial, and other manufactured goods to services businesses in software, architectural, and engineering sectors. Ultimately, the study estimated the potential market size, or total addressable market, at over 2.6 million small businesses.

With the proliferation of digital commerce tools and with over 95 percent of the world’s consumers living outside the United States, international sales represent a rich growth opportunity for small businesses. Indeed, businesses that export are more resilient, expand faster, and create higher paying jobs for Americans.

My colleague, District Director Tim Jeffcoat agrees. With his finger on the local pulse of the Houston-area economic market, he knows that exporting can be both an enormous growth opportunity, but at the same time filled with a daunting set of challenges to navigate. In his

Houston area network alone, they have over 200 advisors, mentors, and counselors that can guide you to develop a robust exporting plan, connect you with capital to fund your overseas expansion, and can even help you pursue a competitive grant to kick-start international sales.

This is exactly the case for Pat Hartmann, founder of Hartmann’s Inc., an Abilene, TX-based woman-owned small business. As a manufacturer of high-quality parts from state-of-the-art metal fabrication and welding departments, Hartmann has leveraged international sales to grow her company over three generations. In her words: “exporting has allowed us to become competitive in multiple markets throughout the entire world. It has diversified our knowledge base allowing us to work in manufacturing situations that span multiple types of standards including European and Japanese. Exporting now makes up 20 percent of our sales.”

As a result, Regional Administrator Ted James and I are among the many Administration officials who are pleased to recognize Pat Hartmann of Hartmann’s Inc. as the 2023 South Central Regional Exporter of the Year. She has established herself as a personal and professional role model due to their expansion and contributions to the community. We are confident that small businesses like these, as well as those identified in our Total Addressable Market study, can start and continue to leverage SBA resources to scale their business and access international opportunities, just as Hartmann did.

Pat Hartmann is one of the more than 11 million female founders the SBA is recognizing during Women’s History Month this March. While the post-pandemic recovery has complicated the economic landscape, we continue to better understand the important role women-owned small businesses play in our entrepreneurial ecosystem. They continue to contribute substantially to the national economy, showcasing innovative solutions and trailblazing techniques to lead the way forward.

If you are a current or future entrepreneur looking for assistance in how to get started or grow internationally, contact the SBA’s Office of International Trade or our network of 68 district offices which offer access to counseling, access to contracts, and access to capital.

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Gabriel Esparza is the associate administrator for the Office of International Trade at the U.S. Small Business Administration.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.