Houston's Karim and Mansour Arem won second place for their ZWITA Spicy Traditional Harissa last year. Photo courtesy of H-E-B

For nine years, H-E-B has been a star maker. Through its annual Quest for Texas Best competition, small companies have become literal household names, filling pantries across the state. Now, a new crop of products has the chance to be crowned as the high-stakes contest seeks entries for its 10th anniversary year.

H-E-B has announced that the Quest for Texas Best is taking applications from February 22 through April 6. Small business owners and entrepreneurs across the state can submit their unique and innovative products to win a combined $70,000 in cash prizes and the opportunity to feature their products on H-E-B shelves.

Since the competition started nine years ago, H-E-B has discovered over 960 exceptional products across the Lone Star State. These have included various food and non-food items, including cookies, coffees, beauty items, toys, home goods, and even roasted crickets. The contest has awarded nearly $2 million in prize money and provided valuable marketing, mentoring, and supplemental support to its winners.

Houston has always been well-represented among the winners. Last year, Karim and Mansour Arem won second place and a $15,000 prize for their ZWITA Spicy Traditional Harissa

To be considered for the contest, interested suppliers and manufacturers can submit details about their products online between February 22 and April 6. After the Call for Entries period is complete, H-E-B's Business Development Managers will select the top applicants who will present their products before a panel of judges chosen by H-E-B on August 9 at Fair Park in Dallas.

The panel of judges will determine the top four winning products and award $25,000 to the Grand Prize winner, the title of "Texas Best," and placement on H-E-B store shelves. The first-place winner will receive $20,000, the second-place winner will receive $15,000, and the third-place winner will receive $10,000.

"As we continue to expand the opportunities for small businesses in Texas and diversify our supplier base through programs like Quest for Texas Best, we look forward to seeing what our fellow Texans bring to the judges' table during the 2023 competition," said James Harris, Sr. Director of Diversity & Inclusion and Supplier Diversity for H-E-B, via a release.

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This article originally ran on CultureMap.

WeWork Labs and NextSeed have teamed up to help Houston's food entrepreneurs. Photo courtesy of WeWork

WeWork accelerator partners with Houston-based investment platform for food entrepreneurship

food for thought

Two Houston programs that exist to help grow and develop food and hospitality startups have teamed up to combine their resources and programming.

WeWork Labs, a global acceleration program with a location in downtown Houston, and NextSeed, a Houston-based online investment platform, have announced a partnership set to begin in December. Together, the two entities will build a support system for Houston-based food entrepreneurs to provide workshops, programming, events, and more.

"Houston food entrepreneurs are keen to solve the big problems the food industry is facing today," says Carlos Estrada, head of WeWork Labs in Houston, in a news release. "Houston is among the leading cities for startup innovation and we see our partnership with NextSeed as an exciting first-of-its-kind initiative that will prove to support even more food entrepreneurs in the area, arming them with the network and tools they need to get their concepts off the ground and transform into leading businesses."

WeWork brings in its international food labs programming, and NextSeed will be able to provide access to capital through its platform. In March, the company launched NextSeed Space — a pop-up retail and kitchen space for startups to test their food and operations.

"Since inception, NextSeed has been focused on developing a world-class technology platform to democratize finance and strengthen local communities," says NextSeed CEO, Youngro Lee, in a news release. "By partnering with WeWork Labs, we are excited to be able to expand the level of support we can provide to our clients and member businesses through services like coaching, mentoring and dedicated workspace to help them ultimately reach their goals."

The first joint event hosted will be a reception and panel on December 12 from 6 to 8:30 pm at WeWork's Jones Building location in downtown. For event details, click here.

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Microsoft partners with Rice University's OpenStax on AI teaching tool

group project

Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”

Houston ranks among the 15 best cities in America for 2025

Ranking It

A new national report ranking the best cities in America has declared Houston is the 13th best U.S. city in 2025.

The annual "America's Best Cities" report from Resonance Consultancy, a Canada-based real estate and tourism marketing firm, ranks the relative qualities of livability, cultural "lovability," and economic prosperity in America's principal cities with metropolitan populations of 500,000 or more.

These top 100 cities "brilliantly weave local culture with economic prospects, aligning with global and domestic travel trends to create premier experiences for both residents and travelers."

Houston's new placement is three spots lower than its triumphant No. 10 rank in 2024. Though it no longer holds a prized top-10 spot, the report hails Houston as a "coveted hometown for the best and brightest on earth."

Among Houston's other shining attributes are its booming population growth – which has now grown to a staggering 7.51 million people – plus its competitive real estate market and a vibrant hospitality and culinary scene. Additionally, Houston earned a well-deserved No. 4 rank in the report's "restaurants" subcategory.

"A 221-room Home2 Suites/Tru by Hilton debuted near Toyota Center in March, while Marriott’s newly renovated Residence Inn NASA/Clear Lake keeps surging visitors happy," the report said. "West Houston’s Greenside will convert 35,000 square feet of warehouses into a park-laced retail hub by 2026, while America’s inaugural Ismaili Center, rising along Allen Parkway, remains on schedule for later this year, adding yet another cultural jewel to H-Town’s festival-fueled mosaic."

The report additionally puts a large focus on Houston's innovative energy sector and its numerous large companies that boost the local economy and create thousands of jobs. Several of these Houston-based companies are some of the best places to work, according to U.S. News and World Report.

One such company that was specifically praised in the report was the HyVelocity Hub, which aims to "ensure economic resilience and long-lasting, domestic energy production" along the Gulf Coast.

"The HyVelocity Hydrogen Hub just locked in up to $1.2 billion from the U.S. DOE, targeting 45,000 jobs and slicing 7.7 million tons of CO₂ a year," the report said.

Elsewhere in Texas

Dallas (No. 14) and Austin (No. 15) ranked right behind Houston in the top 20, while San Antonio sank into the No. 41 spot after previously ranking 32nd last year. El Paso also fell from No. 83 in 2024 to No. 100 this year.

Jason McGrath, the executive vice president and head of U.S. Corporate Reputation at Ipsos, said in the report that American cities are proving their resiliency as they are faced with "climate issues, increasing infrastructural demands, and shifting geopolitical landscapes affecting international relations and travel."

"Despite these hurdles, cities are creatively reinventing themselves to shine as examples of cultural vibrancy and innovation, keeping their competitive edge both locally and globally," McGrath said. "Our report shows that the allure of American cities remains strong, thanks to their rich diversity and vast attractions — from natural wonders to buzzing cultural hubs."

The top 10 best cities in America in 2025 are:

  • No. 1 – New York City, New York
  • No. 2 – Los Angeles, California
  • No. 3 – Chicago, Illinois
  • No. 4 – San Francisco, California
  • No. 5 – Seattle, Washington
  • No. 6 – Miami, Florida
  • No. 7 – Boston, Massachusetts
  • No. 8 – Washington, D.C.
  • No. 9 – Las Vegas, Nevada
  • No. 10 – San Diego, California
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This article originally appeared on CultureMap.com.

Houston biosciences company opens new sequencing center for drug development

bioscience breakthroughs

Houston-based Avance Biosciences has launched the Next-Generation Sequencing Center of Excellence, designed to enhance the company’s sequencing capabilities for drug development. Specifically, the facility at the company’s main campus in Northwest Houston will pursue breakthroughs in biologics, cell therapy and gene therapy.

In the drug industry, sequencing refers to studying nucleotides in DNA and RNA molecules. Nucleotides are the building blocks of DNA and RNA.

“This is a major milestone for Avance Biosciences as we continue to support the evolving needs of biologics and cell and gene therapy developers,” Xuening “James” Huang, co-founder, CEO and chief technology officer of Avance, said in a news release. “By consolidating state-of-the-art sequencing platforms and scientific talent, we’ve created a highly capable organization ready to solve complex genomic challenges with precision and compliance.”

In 2013, Avance rolled out next-generation sequencing (NGS) that complies with federal guidelines. Since then, Avance “has remained at the forefront of regulated sequencing services,” the company said. “The launch of the (new center) strengthens the company’s ability to deliver accurate, reproducible, and regulatory-aligned sequencing data across a wide array of therapeutic modalities.”

Cal Froberg, senior vice president of sales and marketing at Avance, said pharmaceutical and biotech clients trust the company’s technical capabilities and regulatory compliance.

“With the ever-changing global landscape and increasing scrutiny around international sample shipments, conducting advanced, cost-effective NGS testing domestically is now more feasible than ever,” Froberg said. “Our clients have confidence that their samples will remain in the U.S.”

Avance, founded in 2010, plans to hold an open house at the new facility in September to showcase its capabilities, technology, talent, and services. The company’s services include sequencing, molecular biology, cell-based testing, and bioanalytical testing.