Understanding the Fly America Act is important for all researchers planning government-funded travel. Graphic by Miguel Tovar/University of Houston

Commercial aviation witnessed a transformative shift following World War II. Initially reserved for military purposes, commercial air travel began to flourish as civilians embraced its convenience. This surge in air travel highlighted the necessity for regulating the industry.

In response, the Federal Aviation Administration, or FAA, emerged from the Federal Aviation Act of 1958, later becoming a component of the Department of Transportation under the Department of Transportation Act in 1967.

The evolution of air travel regulation continued in 1974 with the enactment of the Fly America Act. Designed to safeguard U.S. interests in international air travel funded by the government, this act prioritizes U.S. airline carriers. This initiative serves both to support domestic airlines and promote the U.S. aviation industry on a global stage when passengers travel on federal funds.

What some might not know is this legislation can impact researchers and their organizations.

Importance for researchers

Adhering to the Fly America Act applies not only to federal government employees but also their dependents, grantees, and other travelers funded by federal resources. Even foreign researchers visiting the U.S. under federally funded grants must choose U.S. flag air carriers for their travel.

A U.S. flag air carrier should not be confused with a traditional flag carrier. These are airlines that have historically been government-owned or are otherwise closely tied to the identity of a particular country, like British Airways or Aeroméxico. U.S. flag air carriers encompass a wide range of airlines, including smaller entities like Air Wisconsin Airlines and Avelo, a new carrier based in Houston. You can find a comprehensive list of U.S. flag air carriers here.

Navigating exceptions

While the Fly America Act carries strict guidelines, exceptions do exist. Instances where no U.S. flag air carriers serve the destination or where such carriers would extend the trip by over 24 hours warrant special consideration. In these cases, maintaining meticulous records is essential in order to validate the use of non-U.S. airlines. A list of exceptions can be found here.

Open Skies Agreements introduce another facet to the Fly America Act. These agreements between the U.S. Government and other countries enable travelers, including researchers, to use foreign air carriers for government-funded international travel. Several countries, including those in the European Union, Australia, Switzerland, and Japan, maintain Open Skies Agreements. Flights on British Airways are no longer permitted under an Open Skies Agreement due to the United Kingdom’s exit from the European Union. Proper documentation is essential when claiming a Fly America Act exception, even if covered under an Open Skies Agreement. Detailed travel itineraries, internal agency forms, and evidence of a Fly America exception must be included in travel receipts.

The Big Idea

Compliance with the Fly America Act ensures your travel expenses are reimbursable on government grants. It’s important to remember that cost and convenience are not exceptions to the act. A thorough understanding of Fly America Act’s provisions and exceptions is a must before you book your next flight.

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This article originally appeared on the University of Houston's The Big Idea. Sarah Hill, the author of this piece, is the communications manager for the UH Division of Research.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.