A growing number of independent professionals call Houston home. Photo via Pixlr

Visitors to Memorial Park on an early weekday afternoon probably have to stop and wonder where all these people are coming from. Don’t they have work to do?

Maybe they do, but on their own schedules. Fiverr, a marketplace for connecting freelancers and new clients, released its fifth annual Freelance Economic Impact Report, ranking Houston as the tenth fastest-growing city for freelancers.

According to the report, some 144,000 workers in Houston made $6.6 billion. That means the Bayou City led Texas with around $46,000 for per capita income.

Elsewhere in Texas, Austin came in as the fourth fastest-growing city for freelancers. The city's 77,262-person independent workforce earned $3.4 billion in 2021. In Dallas, which came in at No. 8, some 177, 500 workers made $7.6 billion.

Joining Houston, Austin, and Dallas in the top 10 were:

1. Orlando, Florida
2. Nashville, Tennessee
3. Miami, Florida
5. Tampa, Florida
6. Las Vegas, Nevada
7. Charlotte, North Carolina
9. Portland, Oregon

Although on the surface the report focuses on geography, it collected data that shows eight out of 10 freelancers believe they can live anywhere and work anytime. However, fewer than half reported that it was “a primary factor” in becoming freelancers, and a third said that work was “a primary influence” in their choice of location.

Most important, 70 percent of respondents said they were “highly satisfied” with working independently.

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This article originally ran on CultureMap.

Houston was home to more than 117,000 skilled freelancers in 2018. Photo courtesy of Common Desk

Houston flourishes as one of the nation's top hubs for freelancers

Self-employment Surge

It's no wonder coworking is taking off in Houston. A new study shows the community of skilled freelance workers in Houston ranks as one of the biggest in Texas — and the United States.

The study, commissioned by freelance marketplace Fiverr and conducted by market research firm Rockbridge Associates, indicates Houston was home to an estimated 117,260 skilled freelancers who generated more than $4.1 billion in revenue in 2018, just slightly less than the financial haul in 2017.

Houston ranked second statewide and 11th in the U.S. among major metro areas for the size of the skilled-freelancer workforce and for the amount of revenue produced, according to the study. Between 2017 and 2018, Houston's pool of skilled freelancers grew 2.5 percent.

From 2011 to 2016, according to the study, Houston's community of skilled freelancers increased 7.7 percent, while revenue declined slightly by 7.8 percent. The Fiverr study places skilled freelancers in three buckets: creative, technical, and professional. These freelancers include attorneys, graphic designers, musicians, software engineers, accountants, and consultants. Any self-employed person whose work requires "specific skills and abilities" was counted in the study; excluded were folks like Uber and Lyft drivers.

"Highly skilled freelancers are an understudied and often overlooked segment of the workforce," Brent Messenger, Fiverr's vice president of public policy and community, says in a release. "By analyzing the data around these … workers, we're able to get a clear picture of the types of jobs they're doing, the amount of revenue they're generating, and the cities in which they're having the most impact."

DFW ranked first in Texas and seventh nationally in the study. In 2018, DFW was home to an estimated 154,617 skilled freelancers who generated nearly $6.38 billion in revenue in 2018, up 5.4 percent from the previous year.

While DFW dominates Texas in terms of freelance population and revenue, Austin boasts the fastest-growing freelance scene.

In 2018, the estimated 67,044 skilled freelancers in the Austin metro area produced nearly $2.7 billion in revenue, up 7.5 percent from 2017, the study says. During the one-year period, Austin's pool of skilled freelancers grew 7.4 percent. The study pegged Austin at No. 18 nationally for the size of the population and revenue of skilled freelancers.

From 2011 to 2016, according to the study, Austin's community of skilled freelancers shot up by 26 percent, with revenue climbing 31 percent. The study identified Austin and Nashville as the country's two fastest-growing hubs for skilled freelancers.

A recent study by commercial real estate website CommercialCafé found that Austin, Dallas, and Houston ranked among the most affordable U.S. cities for freelancers. Meanwhile, personal finance website NerdWallet in 2016 ranked Austin as the best place in the U.S. for freelancers, with Dallas at No. 3, Fort Worth at No. 8, and Houston at No. 15.

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A version of this story originally appeared on CultureMap.com.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."