ArtPark Moving Studios — a local nonprofit that provides art programming for at-risk children — took home a big prize at last year's Project Flourish. Courtesy of First Presbyterian Church

First Presbyterian Church of Houston launched the second round of Project Flourish, a social entrepreneurship contest, on August 18.

The contest is "a creative invitation to the community to help bring fresh ideas to the issues that face a major metropolitan city like Houston," reads a news release. The pitch competition is open to for-profit or nonprofit ideas. What's on the line? Up to $250,000 in seed money, to be divided among an undetermined number of winners as the judges see fit.

Although the church has held the competition in the past, it has made some changes to the newest iteration of the program. Past applicants were not required to have a Houston focus, but this year's individuals and teams must live within 50 miles of downtown Houston and their idea must impact Houston. Those who make it to the semi-final round will be invited to join the eight-week accelerator program, in which they will receive consulting and mentoring in preparation for pitching their ideas to the judges.

Austin Hermann, FPC's Director of the Center for Faith, Work, and Innovation, oversees Project Flourish. When InnovationMap asked him why the contest matters for Houston, Hermann says it's about lending a helping hand to Houston entrepreneurs.

"When you look at all the different groups that are trying to start things in Houston, there's a major gap in the ecosystem… Project Flourish is trying to fill that gap," he says. "We want to connect Houston-based and Houston-focused entrepreneurs who are in the earliest stages of idea formation to the resources of a church — social, intellectual, and financial capital — in a way that other institutions don't because they're not interested in small deals. [We offer] impact investing for and towards groups of individuals who can't get that access anywhere else."

According to a release, in Project Flourish's inaugural round, which concluded in March 2018, funding recipients included art studio on wheels nonprofit ArtPark Moving Studios, which won $55,000, and Rescue Houston, which claimed a $45,000 prize and focuses on empowering victims of sex trafficking.

Hermann says he's most excited about the new Houston emphasis this year as well as the opportunity to get new people involved. The program process is largely the same, but allows a new set of entrepreneurs, application screeners, navigators, skills coaches, and judges to take part.

"We're putting a call out for new ventures [that are] seeking the good of Houston."

For more information or to apply, please visit projectflourish.org. The application is live now through November 1.

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

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Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.