Fervo Energy and Syzygy Plasmonics were recognized for their energy innovation. Photo via Getty Images

A pair of Houston energy startups have been named among the 10 most innovative energy companies for 2024.

Fast Company magazine just placed Fervo Energy and Syzygy Plasmonics on its energy innovation list. In all, 606 companies and organizations across a variety of industries were recognized for “reshaping industries and culture.”

Fervo produces carbon-free geothermal energy. Its existing geothermal project is in Nevada, and it’s building a geothermal project in Utah. The company recently raised $244 million.

“Solar and wind are cheap, but they don’t provide the kind of always-on dispatchable electricity that hydropower, hydrogen, and nuclear do; even at current high prices, enhanced geothermal is still cheaper than those other sources,” Fast Company notes.

The Fast Company accolade comes shortly after Time and Statista named Fervo one of the top greentech companies for 2024.

By relying on light rather than combustion to generate chemical reactions, Syzygy is taking on the use of fossil fuels in the chemical industry, Fast Company points out. Fossil fuels account for about 18 percent of the world’s industrial CO2 emissions.

Fast Company outlines some of Syzygy’s accomplishments in 2023:

  • Gained an undisclosed amount of funding from Mitsubishi Heavy Industries.
  • Completed its Pearland manufacturing facility.
  • Wrapped up 1,000 cumulative hours of testing on its ammonia-splitting reactor cell, capable of producing 200 kilograms of hydrogen per day.
CodeLaunch named its winner — and more Houston innovation news. Photo courtesy of Honeycomb

Houston startup secures bank partnership, energy tech co. wins competition, and more

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Houston startup founders have been moving and shaking in the local innovation ecosystem — from being recognized for their out-of-this-world innovation to big wins.

In this roundup of Houston startup and innovation news, a Houston company snags a major partnership, an energy tech startup wins big on stage, and more.

The Postage gets a new partner

The Postage platform will be available to AmBank Company's employees, customers, and their families. Photo courtesy of The Postage

A Houston tech platform that streamlines estate and legacy planning has entered into a partnership with AmBank Company — American State Bank, American Investment & Trust, and Perspective Insurance — in Sioux Center, Iowa. The bank will deliver The Postage's services to its employees, customers, and their families.

The Postage unique platform allows users important information organizational tools, as well as state-specific will document creation. The technology also allows users to share meaningful family memories, write future messages, and collaborate with loved ones of their choosing.

"Community is at the core of everything American State Bank does. They exemplify that by supporting their customers through the myriad of choices that arise while navigating their financial lives. The Postage fits right into that, and we are thrilled to share our platform with their employees and customers in their planning and organization efforts," says Emily Cisek, CEO and co-founder of The Postage, in a news release. "We hope to grow awareness of the family-driven digital solution and provide AmBank's customers the opportunity to gain control and safeguard their critical information. We look forward to providing AmBank's customers with the guidance they need to protect their wealth and wisdom now and for generations to come."

The partnership, which rolled out last month, was announced as American State Bank and the family of brands celebrated 50 years of business.

"Our commitment to delivering outstanding service and top-notch products to our customers, colleagues, and community has been unwavering for over half a century," says Joel Westra, AmBank first vice president. "This partnership allows us to extend our digital services while staying true to our core values of connection and community.

"Our team has witnessed the struggles of families coping with losing a loved one, we recognized the need for a service like The Postage," he continues. "Far too often, people are uncertain about the next steps, the whereabouts of important documents, and even their loved one's final wishes. We recognize that to prevent these challenges, families need help navigating difficult conversations and guidance on how to get started with their planning, which The Postage provides."

E360 wins Houston startup competition

E360 and Honeycomb Software share the win at the 2023 Houston CodeLaunch event. Photo by Natalie Harms/InnovationMap

CodeLaunch, a traveling seed-stage accelerator, hosted its second Houston startup pitch competition last week, and a Houston energy efficiency startup emerged victorious.

E360 won the top prize at the event on March 2. The program paired six finalists with consultant development teams to pitch and compete for up to $150,000. The startup's technology is a holistic building solution that monitors both the energy efficiency and indoor air quality of commercial buildings.

“The goal I pursued at CodeLaunch was to meet industry leaders and investors who can help take the product to the next level," says Mat Bonassera, chief enterprise architect at E360, in a news release. “The vast majority of buildings are both incredibly inefficient as well as dangerous to their occupants, due to the dangerous levels of compounds in the air.

"We solve both these complex problems at the same time," he continues. "This is unheard of in our industry. We do this by monitoring vast sums of IOT data and then using Machine Learning and real-time monitoring we adjust the building to optimize its performance. This is a revolutionary way to look at commercial buildings."

E360 shares the win with its partner development team Honeycomb Software, an international custom software development company. The provided hands-on support to E360 scale during a two-day hackathon held February 25 and 26.

“The desire to promote energy efficiency of the buildings and the sustainability in business influenced our decision of whom to work with during the Hackathon," says Oleksandr Semeniuk, CEO of Honeycomb Software, in the release. "Our team worked tirelessly to expand the functionality of E360, and this victory is a testament to their hard work and dedication."

Axiom named among most innovative companies

KBR is one of Axiom Space's partners on its new NASA-sanctioned ISS project. Photo via AxiomSpace.com

Fast Company named it's 50 most innovative companies — and Axiom Space, a Houston-based commercial, full-service orbital mission provider, was named No. 49 on the list. It was also recognized as one of the most innovative space tech companies "for going to space without a chaperone," per the magazine.

The article recognized several of Axiom's accomplishments, including:

  • Managing the first all-private mission to the International Space Station in April of 2022. The mission sent a four-person crew into space for 17 days.
  • Developing plans to expand the international community of space explorers, including Italy, Canada, New Zealand, and others.
  • Building a module to attach to the ISS, which is progress toward the world’s first commercial free-floating space station.

“In the space business, there’s a big focus on the transportation, the rockets,” Michael Suffredini, president and CEO of Axiom, tells Fast Company. “But if you think about the railroads that were built across the U.S., they were built to serve a destination. Without a reason to go somewhere, they wouldn’t exist. We’re building the destination in space—the real estate to allow multiple businesses to operate in low-Earth orbit and take advantage of the microgravity environment.”

NASA also makes the ranking for "showing that a public space program can still do big things," according to the list.

Calling all student-founded startups and businesses

Rice and UH have programs for startup and small business entrepreneurs. Photo via uh.edu

Rice University and the University of Houston have upcoming deadlines for their summer accelerators. The summer programs all operate in coordination with each other and offer support for student, faculty, or staff founders and their startups and small businesses.

The four programs, and their focus and application deadlines, are as follows:

  • Rice's OwlSpark is focused on early-stage startup teams with at least one Rice student, faculty, or staff founders to grow from innovation to commercialization. Apply by March 13.
  • UH's RedLabs is focused on early-stage startup teams with at least one UH student, faculty, or staff founders to grow from innovation to commercialization. Apply by March 31.
  • Rice's BlueLaunch is focused on non-tech small business entrepreneurs who are either student, faculty, or staff at Rice. Apply by March 13.
  • UH's Red Launch is focused on non-tech small business entrepreneurs who are either student, faculty, or staff at UH. Apply by March 31.

Dr. Peter Hotez and Dr. Maria Elena Bottazzi have been recognized by Fast Company for their leadership in developing low-cost COVID vaccine. Photo courtesy of Texas Children's

Houston doctors recognized among top creative leaders in business

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This week, Fast Company announced its 14th annual list of Most Creative People in Business — and two notable Houstonians made the cut.

Dr. Peter Hotez and his fellow dean of the National School of Tropical Medicine at Baylor College of Medicine, Dr. Maria Elena Bottazzi, were named among the list for “open sourcing a COVID-19 Vaccine for the rest of the world.” The list, which recognizes individuals making a cultural impact via bold achievements in their field, is made up of influential leaders in business.

Hotez and Bottazzi are also co-directors for the Texas Children's Hospital's Center for Vaccine Development -one of the most cutting-edge vaccine development centers in the world. For the past two decades it has acquired an international reputation as a non-profit Product Development Partnership (PDP), advancing vaccines for poverty-related neglected tropical diseases (NTDs) and emerging infectious diseases of pandemic importance. One of their most notable achievements is the development of a vaccine technology leading to CORBEVAX, a traditional, recombinant protein-based COVID-19 vaccine.

"It's an honor to be recognized not only for our team's scientific efforts to develop and test low cost-effective vaccines for global health, but also for innovation in sustainable financing that goes beyond the traditional pharma business model," says Hotez in a statement.

The technology was created and engineered by Texas Children's Center for Vaccine Development specifically to combat the worldwide problem of vaccine access and availability. Biological E Limited (BE) developed, produced and tested CORBEVAX in India where over 60 million children have been vaccinated so far.

Earlier this year, the doctors were nominated for the 2022 Nobel Peace Prize for their research and vaccine development of the vaccine. Its low cost, ease of production and distribution, safety, and acceptance make it well suited for addressing global vaccine inequity.

"We appreciate the recognition of our efforts to begin the long road to 'decolonize' the vaccine development ecosystem and make it more equitable. We hope that CORBEVAX becomes one of a pipeline of new vaccines developed against many neglected and emerging infections that adversely affect global public health," says Bottazzi in the news release from Texas Children's.

Fast Company editors and writers research candidates for the list throughout the year, scouting every business sector, including technology, medicine, engineering, marketing, entertainment, design, and social good. You can see the complete list here

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Solugen has been named among the most innovative companies in the world — and was deemed the No. 1 most innovative manufacturers. Photo via Getty Images

Houston startup ranks as a top innovative company in the world

No. 1

A Houston biotech startup is now in rarified air.

Solugen ranks second on Fast Company’s 2022 list of the 50 most innovative companies in the world. It also sits at No. 1 on the magazine’s list of the world’s most innovative manufacturers.

Solugen’s process converts corn syrup into industrial chemicals, cutting down on carbon emissions generated by traditional production of chemicals. Carbon dioxide from chemical production is one of the biggest contributors to industrial greenhouse gas emissions.

“Right now, the $6 trillion chemicals industry relies on oil, natural gas, and coal to make ingredients used in everything from laundry detergent and running shoes to fertilizer. It’s a dirty process,” Fast Company reported last December.

According to Fast Company, Solugen’s process for producing a chemical uses nearly all of the feedstock put into it.

“The carbon-negative process and Solugen’s ability to sell flexible amounts of chemicals to companies looking to lower their own footprint have helped the company make inroads in a traditionally slow-moving industry,” the magazine says.

Fast Company notes that Solugen launched in 2016 with four chemicals and another 17 in development. The chemicals are being used in water treatment, in concrete production to reduce cement use, and in agriculture to deliver nutrients to crops, the magazine says.

Last year, Solugen announced it raised $357 million in a Series C round, catapulting it to “unicorn” status. The Series C round bumped up the startup to a valuation of $1.8 billion, pushing it well past the $1 billion mark required for a unicorn designation.

“This fundraising round allows us to continue expanding the footprint of our Bioforge technology to give industries the products they need to reduce emissions in their existing supply chains, without compromising on performance or economics,” Sean Hunt, co-founder and chief technology officer of Solugen, said in a news release about the $357 million round.

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Autonomous truck company rolls out driverless Houston-Dallas route

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Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

Elon Musk's SpaceX site officially becomes the city of Starbase, Texas

Starbase, Texas

The South Texas home of Elon Musk’s SpaceX rocket company is now an official city with a galactic name: Starbase.

A vote Saturday, May 3, to formally organize Starbase as a city was approved by a lopsided margin among the small group of voters who live there and are mostly Musk’s employees at SpaceX. With all the votes in, the tally was 212 in favor to 6 against, according to results published online by the Cameron County Elections Department.

Musk celebrated in a post on his social platform, X, saying it is “now a real city!”

Starbase is the facility and launch site for the SpaceX rocket program that is under contract with the Department of Defense and NASA that hopes to send astronauts back to the moon and someday to Mars.

Musk first floated the idea of Starbase in 2021 and approval of the new city was all but certain. Of the 283 eligible voters in the area, most are believed to be Starbase workers.

The election victory was personal for Musk. The billionaire’s popularity has diminished since he became the chain-saw-wielding public face of President Donald Trump’s federal job and spending cuts, and profits at his Tesla car company have plummeted.

SpaceX has generally drawn widespread support from local officials for its jobs and investment in the area.

But the creation of an official company town has also drawn critics who worry it will expand Musk’s personal control over the area, with potential authority to close a popular beach and state park for launches.

Companion efforts to the city vote include bills in the state Legislature to shift that authority from the county to the new town’s mayor and city council.

All these measures come as SpaceX is asking federal authorities for permission to increase the number of South Texas launches from five to 25 a year.

The city at the southern tip of Texas near the Mexico border is only about 1.5 square miles (3.9 square kilometers), crisscrossed by a few roads and dappled with airstream trailers and modest midcentury homes.

SpaceX officials have said little about exactly why they want a company town and did not respond to emailed requests for comment.

“We need the ability to grow Starbase as a community,” Starbase General Manager Kathryn Lueders wrote to local officials in 2024 with the request to get the city issue on the ballot.

The letter said the company already manages roads and utilities, as well as “the provisions of schooling and medical care” for those living on the property.

SpaceX officials have told lawmakers that granting the city authority to close the beach would streamline launch operations. SpaceX rocket launches and engine tests, and even just moving certain equipment around the launch base, requires the closure of a local highway and access to Boca Chica State Park and Boca Chica Beach.

Critics say beach closure authority should stay with the county government, which represents a broader population that uses the beach and park. Cameron County Judge Eddie Trevino, Jr. has said the county has worked well with SpaceX and there is no need for change.

Another proposed bill would make it a Class B misdemeanor with up to 180 days in jail if someone doesn’t comply with an order to evacuate the beach.

The South Texas Environmental Justice Network, which has organized protests against the city vote and the beach access issue, held another demonstration Saturday that attracted dozens of people.

Josette Hinojosa, whose young daughter was building a sandcastle nearby, said she was taking part to try to ensure continued access to a beach her family has enjoyed for generations.

With SpaceX, Hinojosa said, “Some days it’s closed, and some days you get turned away."

Organizer Christopher Basaldú, a member of the Carrizo/Comecrudo Nation of Texas tribe, said his ancestors have long been in the area, where the Rio Grande meets the Gulf.

“It’s not just important,” he said, “it’s sacred.”