New Houston accelerator leader dives into first cohort

HOUSTON INNOVATORS PODCAST EPISODE 83

Kate Evinger joins the Houston Innovators Podcast to discuss the latest from gBETA Houston. Photo courtesy of gBETA

Everything's bigger in Texas, but Kate Evinger is focused on zeroing in on a small group of startups to help them in a Texas-sized way.

As director of gBETA Houston, Evinger says the program, which expanded to Houston in 2019, is geared toward supporting companies as they navigate the initial challenges of starting a company.

"We look at early-stage companies, so those that are pre-seed or seed-stage that are looking for mentorship or support," Evinger says on this week's episode of the Houston Innovators Podcast, "and we help get to that next step whether that's to raise an upcoming round or if they are looking to get into an equity-based accelerator program."

The program runs two 7-week cohorts a year — and only five companies join each round. This tight-knit group is to the cohort's advantage, Evinger says.

"It's a very small group that we bring in, and we do this very purposefully, because we like to use a concierge approach, meaning that we tailor the experience to each of the five company's personal goals," she explains.

This week, gBETA Houston announced the latest cohort's member companies, which includes five Houston-based companies: Veza, Upbrainery, FareUpThere, Custodian Corp., and Clyr.

The program, which is a part of Wisconsin-based gener8tor, began May 6 and concludes July 7 with a pitch day. The local operation is housed out of the Downtown Launchpad alongside Impact Hub Houston and MassChallenge Texas.

"The Downtown Launchpad is a phenomenal space," Evinger says. "It's a really amazing collaborative ecosystem for our companies to be able to leverage."

Evinger shares more about the new cohort growth and gener8tor's other opportunities on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


gBETA Houston, which is based out of Downtown Launchpad, has announced its latest cohort. Photo courtesy of the Downtown Launchpad

Global accelerator announces 5 startups to its Houston cohort

early-stage support

Five Houston companies have been tapped to participate in a Houston-based, early-stage startup accelerator with a national presence.

The accelerator, gBETA, selected the five Houston companies out of over 85 applicants. The cohort represents industries like education, travel, and fintech. The summer program launched on May 6 and will take place over seven weeks before concluding on July 7 at the gBETA Houston Pitch Night.

Here are the five startups selected from Houston:

  • Clyr, led by CEO and Co-founder Jeff Jensen, makes pools smarter and more sustainable through its eco-friendly approach. Clyr connects users with their pools through the first ever solar-powered WiFi-connected Smart Skimmer device and automates pool care using renewable resources. Since launching in 2020, Clyr is located in hundreds of pools across the US and has analyzed over 2 million pool chemistry data points and given over 100,000 recommendations for fixes.
  • Custodian Corp's software-as-a-service platform solves the data management and valuation pain points of venture capital and private equity managers faster and at a fairer price than competitors. Led by CEO Federico Jost, Custodian's main product is the CPMTOOL, a cloud-based solution to collect, aggregate, organize and analyze portfolio company data for monitoring and reporting purposes. Custodian launched in January of 2021, has six pilots to date and has tripled revenue since February of 2021.
  • FareUpThere's travel platform takes the mystery out of booking the perfect flight. Led by CEO and Co-Founder Malcolm Woods, FareUpThere's restaurant-style menu of flight amenities allows passengers to easily customize their perfect flight ranging from exact inches of legroom to whether the flight has Netflix. FareUpThere successfully launched a private beta in December of 2020.
  • UpBrainery, led by CEO and Founder Ghazal Qureshi, created a marketplace provides an AI-driven software platform and research-based, results-driven curriculum to students, parents, teachers and organizations. UpBrainery's journey mapping tool aligns a students educational interests and learning styles with their goals to visualize the steps needed to achieve them. Since launching in March of 2020, UpBrainery has provided over 5,000 students with opportunities for digital learning and customers include Whataburger, Girl Scouts and The Houston Rockets.
  • Veza, Launched in December, connects the world's influencer marketing experts through its professional social network. Veza's network supports both sides of the influencer marketing industry; the businesses searching for talent and the influencers looking for opportunities. Led by CEO Efrain Batista, Veza offers businesses access to the world's first free influencer search and discovery platform.

The program, which has been operating online due to the pandemic, has its local office in the Downtown Launchpad.

"Downtown Launchpad starts at the edge of technology and entrepreneurship, where cutting-edge ideas can quickly be explored, and future technology can become high-impact businesses. It was developed around a framework of resources to help entrepreneurs as they seamlessly navigate through the stages of startup production," says Robert Pieroni, director of Economic Development of Central Houston, in the release.

The free accelerator is a part of Madison, Wisconsin-based gener8tor's suite of accelerators, and announced its plan to launch in Houston in September 2019. The program's inaugural cohort premiered in May and conducted the first program this summer completely virtually. The second cohort took place last fall.

"In order to harness the impact of entrepreneurs and innovators of new technologies, an ecosystem involving many parts is needed," continues Pieroni. "That is why we recruited the nationally acclaimed startup accelerator, gener8tor, to our city. We're thrilled that gener8tor is one of Downtown Launchpad's resident partners and are helping us continue our mission to inspire innovation in the Houston community. I look forward to the impact created by the startups in this year's cohort."

Kate Evinger leads the local program as director. She recently assumed this role, and this will be her first cohort to direct.

"Houston is at a pivotal moment in time with the exciting innovations taking place in the ecosystem," says Evinger in the release. "I'm thrilled to be a part of the Houston community supporting the work of these incredible founders in the gBETA Houston Summer 2021 program."

Stream a recent episode of the Houston Innovators Podcast where Evinger shares what she's excited about for this cohort:

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

View All Listings