It's time for a broader approach to ensure that the U.S. meets energy demands and leads the world in innovation and education. Photo via Getty Images

U.S. energy consumption is projected to rise nearly 20 percent over the next decade — driven by advancements like AI, increasing electrification, and the growing demand for electric vehicles. While attention often centers on the technologies that generate power, the driver behind this transformation is the skilled workforce, which comprises men and women dedicated to enabling the nation's growth. Ensuring a steady supply of qualified workers is imperative for meeting the energy demands of the coming decade.

Developing this talent pipeline starts with a commitment to education. As the energy landscape evolves rapidly, educators play a crucial role in equipping the next generation with the skills to embrace new technologies and adapt to changing industry demands. This commitment to education is central to the Energy Education Foundation's (EEF) mission. It's also a cornerstone of EEF partner and board member, Coterra Energy's, efforts to be recognized as a leader in energy education.

At a recent Energy Education Exchange, hosted by Coterra and EEF, in collaboration with industry partners such as the American Petroleum Institute (API) and the Consumer Energy Alliance, over 50 educators and industry leaders gathered in Houston to address this need.

During the three-day event, educators, administrators, and industry professionals were immersed in the many facets of the oil and gas industry, learning best practices for incorporating energy education into their programs.

Educators experienced an in-depth tour of the San Jacinto College Center for Petrochemical, Energy, and Technology. As the largest petrochemical training facility in the Gulf Coast region, the center offered a unique look at industry-standard equipment, including a multifunctional glass pilot plant lab, a glycol distillation unit, and 35 specialized training labs. Participants engaged in demonstrations led by faculty and students, exploring circuits, on-campus refineries, and advanced machinery — essential experiences that bring classroom lessons to life.

The event also highlighted efforts at the high school level, exemplified by a presentation and tour at Energy Institute High School in Houston's historic Third Ward. The Institute showcased how project-based learning, robotics, and hands-on fabrication labs are shaping students' skills for the energy sector. The high school's mission aligns perfectly with EEF’s goals: sparking interest in energy among younger students, developing their skills, and paving a pathway toward lifelong careers in the industry.

API's "Lights On" reception concluded the first day, promoting networking among educators and industry professionals. By facilitating these connections, we are ensuring that educators learn about energy careers and establish ongoing relationships that can translate into opportunities for their students.

Keynotes throughout the exchange included Peter Beard, Senior Vice President of the Greater Houston Partnership, and Chris Menefee, President of Unit Drilling Company, who further emphasized the critical need for workforce development. Beard noted, "As our economy grows, we must ensure we have the electrons and the workforce to support that growth." He stressed that aligning skills with job requirements is more than just matching credentials; it's about upskilling and offering real career mobility.

Menefee echoed this sentiment, acknowledging the pressures on educators to prepare students for an ever-changing job market. He underscored his company's commitment to "quality over quantity" in hiring, prioritizing well-trained individuals, and emphasizing the value of strong foundational skills, which begin in the classroom, especially career and technology classrooms.

The Energy Day Festival in Houston provided an additional opportunity for educators and administrators to engage directly with the industry. Thousands attended, visiting booths set up by companies, trade groups, and educational institutions. EEF's own Mobile Energy Learning Units offered interactive exhibits designed to teach students of all ages about energy and career opportunities. The Units appearance at Energy Day was made possible by the American Petroleum Institute.

Looking forward, the U.S. must expand opportunities for the next generation of energy workers and provide educators with the necessary resources. The Energy Education Exchange is a significant step forward, but one initiative alone cannot shape an entire workforce. All stakeholders involved must invest in tools, training, and programs that empower educators and provide opportunities for students. As Domestic Policy Advisor Neera Tanden recently stated, "Apprenticeships are essential for advancing the economy and building critical skills."

It's time for a broader approach to ensure that the U.S. meets energy demands and leads the world in innovation and education. At the Energy Education Foundation, we are proud to be at the forefront of this mission, working alongside Coterra and other partners. By empowering educators, we empower the next generation—one that will fuel our nation's future. Together, we can build a workforce ready for the challenges ahead.

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Kristen Barley is the executive director of the Energy Education Foundation, an organization dedicated to inspiring the next generation of energy leaders by providing comprehensive, engaging education that spans the entire energy spectrum.

This article originally ran on EnergyCapital.

Here are over 10 can't-miss events for Houston innovators in September.Photo via Getty Images

10+ can't-miss Houston business and innovation events for September

where to be

From energized tech conferences to informative speaker series, September is filled with opportunities for Houston innovators. Here's a roundup of events you won't want to miss out on so mark your calendars and register accordingly.

Go ahead and add the Houston Innovation Awards on November 14 to your agenda as well — and submit a nomination of a deserving Houston startup or innovator online.

Note: This post may be updated to add more events.

September 4-5 — EcoEngineers' Life-Cycle Analysis Academy

A life-cycle analysis (LCA) is a systematic and comprehensive method for evaluating the environmental impact of a product, service, or system from its inception to its end-of-life.

EcoEngineers has performed more than 1,000 carbon LCAs since 2015 and will guide attendees through the leading industry trends and regulations impacting LCAs. The LCA Academy provides an opportunity for industry leaders and practitioners across all sectors to gain hands on experience in a workshop environment.

This event is Wednesday, September 4, and Thursday, September 5, from 8 am to 5 pm at Petroleum Club. Click here to register.

September 5 — Leading Successful Projects: Managing Risk and Uncertainty with New Technology Implementations

Join RCEL at the Ion for an informative discussion on managing risk and uncertainty in new technology projects. Register to attend and enjoy refreshments, along with an opportunity for networking and discussion following a seminar on navigating risks and uncertainties in new technology applications.

During this seminar, Dr. Claudia Zettner, a Rice University professor will provide real-world examples of new technology implementations and how realized risks affected overall project outcomes.

This event is on Thursday, September 5, from 4 to 5:30 pm at the Ion. Click here to register.

September 9-13 — Houston Energy and Climate Startup Week

Greentown Labs, Halliburton Labs, and The Rice Alliance for Technology and Entrepreneurship are joining forces to launch the inaugural Houston Climate and Energy Startup Week 2024. This week will bring together leading energy and climate investors, industry leaders, and startups from across the globe to showcase and discuss innovative and promising companies and technologies that are transforming the energy industry and driving a sustainable, low-carbon energy future.

This event begins Monday, September 9, at 3:30 pm and runs through, Friday, September 13. Click here for the full schedule and to register.

September 9-13 — Houston Energy and Climate Week

Allies in Energy, a 501c3 non-profit, was formed in Texas to address energy education and climate literacy, and will be hosting their inaugural Houston Energy & Climate Week. This week brings together major cities in creating the national conversations and actions around a net zero future and Houston's leading role in driving solutions. The program themes are energy, innovation, industry, food, environmental justice, health, finance, workforce, community engagement, and policy.

This event begins Monday, September 9, at 7 am and runs through September 13. Click here for the full schedule and to register.

September 11 — Houston Methodist Clinician Speaker Series - Dr. Jordan Dale

Houston Methodist's next clinician speaker is Dr. Jordan Dale, the chief medical information officer. Dale will speak about digital transformation at Houston Methodist, the role of artificial intelligence in healthcare, and the importance of responsible AI use.

This event is Wednesday, September 11, from 4:45 to 6 pm at the Ion. Click here to register.

September 12 — Future of Automated Science Symposium

The Future of Automated Science Symposium is the inaugural annual event focused on automated science. As a new and emerging field, bringing together AI, infrastructure at scale, and high-throughput experimentation, Automated Science can offer new paradigms for scientific investigation.

Hear from academic and industry leaders from Carnegie Mellon University, Emerald Cloud Lab, and Opentrons. Learn about the exciting future of Automated Science and network with like-minded scientists and engineers.

This event is on Thursday, September 12, from 8:30 am to 4:15 pm at TMC Helix Park. Click here to register.

September 13 — 17th Annual Advances in Neurology Symposium

There have been significant advances in the diagnosis and treatment of many neurological diseases. Attempts to cover these scientific advances have been made through peer-reviewed journals, national and international society meetings, and consensus statements. This program will emphasize evidence-based strategy for the current treatment of neurological disorders and cutting-edge research in novel therapeutics.

This event is on Friday, September 13, from 8 am to 5:15 pm at Houston Methodist Research Institute. Click here to register.

September 17-20 — Gastech Conference

The Gastech Conference is an essential forum for energy professionals to shape the future of the industry. It sets the industry's critical agenda by driving energy security and transitions. More than 1,000 speakers will discuss the real-world strategies and business models that deliver energy security, shape climate actions for industry-wide decarbonization, and support a sustainable, affordable, and reliable multi-faceted energy system.

This event begins Tuesday, September 17 at 10 am and runs through Friday September 20 at George R. Brown Convention Center. Click here for the full schedule and to register.

September 19 — Carbon to Value Initiative Year 4 Kickoff

The Carbon to Value (C2V) Initiative is a multi-year collaboration between The Urban Future Lab (UFL), Greentown Labs, and Fraunhofer USA. This partnership is driving the creation of a thriving innovation ecosystem for the commercialization of carbontech—technologies that capture, convert and store carbon dioxide (CO₂) into valuable end products or services.

Celebrate the kickoff of Year 4 of the Carbon to Value Initiative, meet the startups that were selected for this year’s cohort, and hear from industry experts.

This event is on Thursday, September 19, from 5:30 pm to 8 pm at Greentown Labs. Click here to register.

September 24 — TMC Cappucino Connections

Mingle with the Texas Medical Center community and learn about exciting upcoming projects while enjoying complimentary cups of coffee.

This event is on Tuesday, September 24 from 8:30 to 10:30 am at TMC Innovation Factory. Click here to register.

September 25-27 — Innovation for Day One

Innovation for Day One is a conference organized by the Rice360 Institute for Global Health Technologies and the maternal newborn health community to explore groundbreaking tools and approaches for healthy outcomes for mothers and babies in resource-limited communities.

This event is from Wednesday, September 25 through Friday, September 27, at the Bioscience Research Collaborative on Rice University's campus. Click here to register.


Adena Power uses three patented materials to produce a sodium-based battery that delivers clean, safe, long-lasting energy storage. Photo via adenapower.com

Ohio startup joins Houston clean tech accelerator

onboarding

A clean energy startup has joined Houston-based Halliburton Labs, an incubator for early-stage energy tech companies.

Adena Power, based in Ohio, uses three patented materials to produce a sodium-based battery that delivers clean, safe, long-lasting energy storage. The startup is trying to capitalize on the 100 terawatt-hour potential for energy storage in the U.S. grid.

“With Halliburton Labs’ support and operational expertise, Adena Power looks to accelerate scaling and take advantage of the high-growth market opportunity,” Nathan Cooley, co-founder and CEO of Adena Power, says in a news release.

Adena, founded in 2022, supplies energy storage batteries for the commercial, industrial, and utility sectors. The startup has collected funding from four investors, according to PitchBook: OhioXcelerate, Third Derivative, BRITE Energy Innovators, and For ClimateTech.

Adena’s addition to Halliburton Labs comes during a momentous year for the company. For example:

  • Adena won the People’s Choice Award at the National Renewable Energy Labs Industry Growth Forum.
  • Adena earned the MAKE IT (Manufacture of Advanced Key Energy Infrastructure Technologies) Prize from the U.S. Department of Energy.

“Our team is ready to collaborate with Adena to help them accelerate their growth to meet the demand for behind-the-meter storage solutions,” says Dale Winger, managing director of Halliburton Labs.

Halliburton Labs is a wholly owned subsidiary of Halliburton, a provider of products and services for the energy industry. The incubator will have pitches at the inaugural Houston Energy and Climate Startup Week next month.

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This article originally ran on EnergyCapital.

A new program at Rice University will educate recent graduates or returning learners on key opportunities within energy transition. Photo via Rice.edu

New program to produce innovative, sustainability-focused workforce for energy industry

coming this fall

A Houston university has committed to preparing the workforce for the future of energy with its newest program.

Rice University announced plans to launch the Master of Energy Transition and Sustainability, or METS, in the fall. The 31 credit-hour program, which is a joint initiative between Rice's George R. Brown School of Engineering and the Wiess School of Natural Sciences, "will train graduates to face emergent challenges in the energy sector and drive innovation in sustainability across a wide range of domains from technology to economics and policy," according to the university.

“We believe that METS graduates will emerge as leaders and innovators in the energy industry, equipped with the skills and knowledge to drive sustainable solutions,” Rice President Reginald DesRoches says in the release. “Together we can shape a brighter, more resilient and cleaner future for generations to come.”

Some of the focus points of the program will be geothermal, hydrogen, and critical minerals recovery. Additionally, there will be education around new technologies within traditional oil and gas industry, like carbon capture and sequestration and subsurface storage.

“We are excited to welcome the inaugural cohort of METS students in the fall of 2024,” Thomas Killian, dean of the Wiess School of Natural Sciences and a professor of physics and astronomy, says in the release. “This program offers a unique opportunity for students to delve into cutting-edge research, tackle real-world challenges and make a meaningful impact on the future of energy.”

The new initiative is just the latest stage in Rice's relationship with the energy industry.

“This is an important initiative for Rice that is very much aligned with the university’s long-term commitment to tackle urgent generational challenges, not only in terms of research — we are well positioned to make significant contributions on that front — but also in terms of education,” says Michael Wong, the Tina and Sunit Patel Professor in Molecular Nanotechnology, chair and professor of chemical and biomolecular engineering and a professor of chemistry, materials science and nanotechnology and of civil and environmental engineering. “We want prospective students to know that they can confidently learn the concepts and tools they need to thrive as sustainability and energy transition experts and thought leaders.”

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This article originally ran on EnergyCapital.

Retirement is coming for the energy industry's workforce. Here's how to prepare for it. Photo via Getty Images

Houston expert shares strategies for addressing  potential workforce shortages

guest column

The energy industry, a vital part of Houston’s business ecosystem, faces the challenge of a shrinking workforce.

A U.S. Chamber of Commerce report indicates the workforce has nearly two million fewer workers today as compared to February 2020. A considerable part of this decline can be attributed to retirement and early retirement rates, with the pandemic prompting three million people to early retirement. Furthermore, with an estimated 10,000 Baby Boomers turning 65 daily, the entire generation is expected to reach retirement age by 2030.

The tight labor market, coupled with the growing brain drain associated with retirement rates, should serve as a wake-up call for employers in the energy sector. There are tried-and-true strategies to prepare businesses for waves of retirement and ensure the knowledge does not walk out the door.

Upskilling: Invest in the workforce

Knowledge and skills go with workers are they retire. To mitigate the brain drain, companies need to invest in upskilling their existing employees and new hires. Establishing formal training and development opportunities can help enrich the workforce to pick up the responsibilities of retiring colleagues. This investment ensures a smooth transition, shows employees they are valued by the organization, and increases employee loyalty and engagement.

Adopting innovative training programs that cater to the specific needs of the energy sector is one approach. Technologies rapidly evolve, and employees must stay current to remain effective in their roles. Investing in the latest training programs, workshops and certifications will enable the workforce to thrive in a rapidly changing industry.

Mentoring programs: Pass the torch

Mentorship programs can play a pivotal role as more employees retire. Experienced employees nearing retirement can mentor younger workers, transferring knowledge and skills while ensuring a seamless transition of expertise. The value of mentorship programs can be priceless for an organization as they help transfer on-the-job learning and experiences that are not taught in the classroom.

A structured mentorship program usually proves most effective as it outlines the responsibilities of the mentors and mentees. A structured approach, which should have built-in accountability measures, ensures there is a productive knowledge transfer process.

Intentional recruitment: Attract and retain talent

A proactive recruitment approach is essential as businesses work to fill knowledge gaps. Companies in the energy sector should seek out talent to bridge the generational divide. This may include targeting candidates who have the relevant skills and knowledge, yet they are willing to adapt to the industry’s changing landscape.

Workplace culture is still a relevant and important component of attracting and retaining top-notch talent. Beyond competitive compensations packages, today’s job candidates look for growth opportunities and a focus on work-life balance.

Retaining knowledge: Document the expertise

Institutional knowledge will walk out the door as experienced employees retire. Companies can prepare for and mitigate the knowledge migration with knowledge-sharing systems and comprehensive documentation processes. An established process can help preserve information that may seem like second nature to more experienced employees and make it accessible to current and future employees. Asking retiring employees to document their expertise and best practices can safeguard their insights within the organization.

Covering bases: Create an alumni network

Retirement does not always mean the employee wants to hang up their proverbial hat entirely. Filling the knowledge gap as employees retire can be daunting. However, the development of an alumni network can extend the life of the institutional knowledge and knowledge-sharing process. Bringing back retirees on a project basis or to consult is a solution benefiting everyone involved.

Every industry must prepare for the impending wave of retirements. The energy industry’s significant impact on the Houston economy requires proactive and thoughtful solutions. The tight labor market and retirement rates should have businesses in this sector working diligently to fill the upcoming knowledge gaps through upskilling, mentoring, intentional recruitment, knowledge-sharing systems and alumni networks. Taking these steps now, the energy industry can circumnavigate workforce shortages and prepare for continued success.

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Jill Chapman is a director of early talent programs with Insperity, a leading provider of human resources and business performance solutions. This article originally ran on EnergyCapital.

This Houston-based media company launched a networking platform to help solve the energy crisis. Screenshots via apps.apple.com

Houston startup launches networking app for next-generation energy workforce

get connected

A Houston-based media organization dedicated to covering the energy industry has officially launched the beta program of their networking app.

After producing zanily named energy podcasts like “Big Digital Energy” and “What the Funk,” Digital Wildcatters is trying to bridge the hiring gap in the energy industry. By providing a platform for individuals to get their questions answered by experts and a space for companies seeking qualified talent, Collide is structured to ignite the next generation of energy innovators. Collide is currently available for users in both the Apple App Store and Google Play Store.

Collin McLelland, co-founder and CEO of Digital Wildcatters, says he aims to expand their professional community through this networking platform. Rather than being a transition away from Digital Wildcatters’ roots as a digital media organization McLelland explains Collide is an integration of the community they have built through podcasts and events into an interactive platform.

“If you look at what we’ve done historically with Digital Wildcatters, we’ve built an extremely engaged community of energy professionals — it’s a next generation community, very young forward thinking professionals that are working towards solving the world’s energy crisis,” McLelland shares.

The roll out of Collide has been intentionally gradual, McLelland says because they want to shape the user experience based on feedback from ongoing focus groups. Currently they have about 1,000 users and are examining how they can make the app valuable to them before providing the platform to a wider audience.

McLelland says there are two major issues within the energy sector that Collide hopes to address — a lack of knowledge about energy verticals and difficulty recruiting talent. McLelland attributes the information gap to how expansive the energy sector is, incorporating beyond oil and gas, everything from renewables to lithium mining. Similarly, by zeroing in on the energy sector, McLelland believes Collide can draw upon the network of talent Digital Wildcatters has already cultivated to tackle recruiting issues.

“What we really see with our platform is being able to bring people together where if you want to find a piece of information, you need to find a subject matter expert, or if you want to find your next job, it happens on the Collide platform,” McLelland says.

Unlike other hiring platforms, Collide offers users the opportunity to look for information about the energy sector by integrating all of Digital Wildcatters’ podcasts and videos into a content search engine. This program is part of their DW Insight subscription product which also has a startup database with overviews of various companies, from their demos to a portal to contact them.

“We hope someday that we’ll have this knowledge base that can be searched and queried to where if you want to find out any piece of information, you’ll be able to find it on (DW Insight),” McLelland explains.

McLelland co-founded Digital Wildcatters with Jake Corley. The two started the Oil and Gas Startups podcast in 2019.

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This article originally ran on EnergyCapital.

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5 Rice University-founded startups named finalists ahead of prestigious pitch competition

student founders

Five student-founded startups have been named finalists for Rice University's prestigious pitch competition, hosted by Rice University’s Liu Idea Lab for Innovation and Entrepreneurship later this month

The teams will compete for a share of $100,000 in equity-free funding at the H. Albert Napier Rice Launch Challenge (NRLC), a venture competition that features Rice University's top student-founded startups. The competition is open to undergraduate, graduate, and MBA students at Rice.

Finalists will pitch their five-minute pitch before the Rice entrepreneurship community, followed by a Q&A from a panel of judges, at Rice Memorial Center Tuesday, April 22.

The first-place team will receive $50,000 in equity-free funding, with other prizes and awards ranging from $25,000 to $1,000. Apart from first-, second- and third-place prizes, NRLC will also name winners in categories like the Outstanding Achievement in Artificial Intelligence Prize, the Outstanding Achievement in Climate Solutions Prize, and the Audience Choice Award.

Here are the five startups founded by Rice students are heading to the finals.

Haast Autonomous

Haast Autonomous is building unmanned, long-range VTOL aircraft with cold storage to revolutionize organ transport—delivering life-saving medical supplies roof-to-roof faster, safer, and more efficiently than current systems.

Founders: Jason Chen, Ege Halac, Santiago Brent

Kinnections

Kinnections' Glove is a lightweight, wearable device that uses targeted vibrations to reduce tremors and improve motor control in Parkinson’s patients.

Founders: Emmie Casey, Tomi Kuye

Labshare

Labshare is an AI-powered web app that streamlines lab inventory and resource sharing, reducing waste and improving efficiency by connecting neighboring labs through a centralized, real-time platform.

Founders: Julian Figueroa Jr, John Tian, Mingyo Kang, Arnan Bawa, Daniel Kuo

SteerBio

SteerBio’s LymphGuide is a patented, single-surgery hydrogel solution that restores lymphatic function by promoting vessel growth and reducing rejection, offering a transformative, cost-effective treatment for lymphedema.

Founders: Mor Sela Golan, Martha Fowler, Alvaro Moreno Lozano

Veloci

Veloci Running creates innovative shoes that eliminate the trade-off between foot pain and leg tightness, empowering runners to train comfortably and reduce injury risk.

Founders: Tyler Strothman

Last year, HEXASpec took home first place for its inorganic fillers that improve heat management for the semiconductor industry. The team also won this year's Energy Venture Day and Pitch Competition during CERAWeek in the TEX-E student track.

Dow aims to power Texas manufacturing complex with next-gen nuclear reactors

clean energy

Dow, a major producer of chemicals and plastics, wants to use next-generation nuclear reactors for clean power and steam at a Texas manufacturing complex instead of natural gas.

Dow's subsidiary, Long Mott Energy, applied Monday to the U.S. Nuclear Regulatory Commission for a construction permit. It said the project with X-energy, an advanced nuclear reactor and fuel company, would nearly eliminate the emissions associated with power and steam generation at its plant in Seadrift, Texas, avoiding roughly 500,000 metric tons of planet-warming greenhouse gas emissions annually.

If built and operated as planned, it would be the first U.S. commercial advanced nuclear power plant for an industrial site, according to the NRC.

For many, nuclear power is emerging as an answer to meet a soaring demand for electricity nationwide, driven by the expansion of data centers and artificial intelligence, manufacturing and electrification, and to stave off the worst effects of a warming planet. However, there are safety and security concerns, the Union of Concerned Scientists cautions. The question of how to store hazardous nuclear waste in the U.S. is unresolved, too.

Dow wants four of X-energy's advanced small modular reactors, the Xe-100. Combined, those could supply up to 320 megawatts of electricity or 800 megawatts of thermal power. X-energy CEO J. Clay Sell said the project would demonstrate how new nuclear technology can meet the massive growth in electricity demand.

The Seadrift manufacturing complex, at about 4,700 acres, has eight production plants owned by Dow and one owned by Braskem. There, Dow makes plastics for a variety of uses including food and beverage packaging and wire and cable insulation, as well as glycols for antifreeze, polyester fabrics and bottles, and oxide derivatives for health and beauty products.

Edward Stones, the business vice president of energy and climate at Dow, said submitting the permit application is an important next step in expanding access to safe, clean, reliable, cost-competitive nuclear energy in the United States. The project is supported by the Department of Energy’s Advanced Reactor Demonstration Program.

The NRC expects the review to take three years or less. If a permit is issued, construction could begin at the end of this decade, so the reactors would be ready early in the 2030s, as the natural gas-fired equipment is retired.

A total of four applicants have asked the NRC for construction permits for advanced nuclear reactors. The NRC issued a permit to Abilene Christian University for a research reactor and to Kairos Power for one reactor and two reactor test versions of that company's design. It's reviewing an application by Bill Gates and his energy company, TerraPower, to build an advanced reactor in Wyoming.

X-energy is also collaborating with Amazon to bring more than 5 gigawatts of new nuclear power projects online across the United States by 2039, beginning in Washington state. Amazon and other tech giants have committed to using renewable energy to meet the surging demand from data centers and artificial intelligence and address climate change.

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This story appeared on our sister site, EnergyCapitalHTX.com.

UH, Baylor researchers make breakthrough with new pediatric leukemia treatment device

childhood cancer

A team of Houston researchers has developed a new microfluidic device aimed at making treatments safer for children with hyperleukocytosis, a life-threatening hematologic emergency often seen in patients with leukemia.

Dr. Fong Lam, an associate professor of pediatrics at Baylor College of Medicine and a pediatric intensive care physician at Texas Children’s Hospital, partnered with Sergey Shevkoplyas, a professor of biomedical engineering at UH, on the device that uses a large number of tiny channels to quickly separate blood cells by size in a process called controlled incremental filtration, according to a news release from UH.

They tested whether performing cell separation with a high-throughput microfluidic device could alleviate the limitations of traditional conventional blood-filtering machines, which pose risks for pediatric patients due to their large extracorporeal volume (ECV), high flow rates and tendency to cause significant platelet loss in the patient. The results of their study, led by Mubasher Iqbal, a Ph.D. candidate in biomedical engineering at UH, were published recently in the journal Nature Communications.

“Continuously and efficiently separating leukocytes from recirculating undiluted whole blood — without device clogging and cell activation or damage — has long been a major challenge in microfluidic cell separation,” Shevkoplyas said in a news release. “Our study is the first to solve this problem.”

Hyperleukocytosis is a condition that develops when the body has an extremely high number of white blood cells, which in many cases is due to leukemia. According to the release, up to 20 percent to 30 percent of patients with acute leukemia develop hyperleukocytosis, and this places them at risk for potentially fatal complications.

The new device utilizes tiny channels—each about the width of a human hair—to efficiently separate blood cells through controlled incremental filtration. According to Lam, the team was excited that the new device could operate at clinically relevant flow rates.

The device successfully removed approximately 85 percent of large leukocytes and 90 percent of leukemic blasts from undiluted human whole blood without causing platelet loss or other adverse effects. It also operates with an ECV that’s about 1/70th of conventional leukapheresis machines, which makes it particularly suitable for infants and small children.

“Overall, our study suggests that microfluidics leukapheresis is safe and effective at selectively removing leukocytes from circulation, with separation performance sufficiently high to ultimately enable safe leukapheresis in children,” Shevkoplyas said in the release.