Here's what you can expect at Houston's Comicpalooza this weekend from esports to Game of Thrones stars

Bend the knee

Comicpalooza takes place Friday, May 9, to Sunday, May 12. Courtesy of Comicpalooza

People from around the world will be flocking to downtown Houston by the thousands, and not just for the Astros and the Rockets. The 11th annual Comicpalooza is taking over the George R. Brown Convention Center from Friday, May 10, to Sunday, May 12.

"This major super block in downtown will be absolutely electric this weekend," Michael Heckman, Comicpalooza president, tells InnovationMap.

Last year, the convention attracted over 50,000 people from 47 states and 17 countries, and it made an economic impact of over $20 million, Heckman says. This year, with the help of Game of Thrones stars and an inaugural ESPN event, Comicpalooza should surpass last year's accomplishments.

Here's what you can expect from this weekend.

A crowd at the panel that has two Game of Thrones actresses

Emilia Clarke (left) plays Daenerys in Game of Thrones, and Nathalie Emmanuel plays her adviser and friend, Missandei. Photos courtesy of Comicpalooza

A panel on Saturday morning at 11 am will have two Game of Thrones stars — Emilia Clarke (Daenerys) and Nathalie Emmanuel (Missandei). The panel is sure to attract the masses, and the two actresses are major gets by the organization.

"To be able to get Emilia Clarke in the middle of the final season of Game of Thrones, with only two episodes to go — the hype has been unbelievable," Heckman says. "To be able to have a pop culture phenomenon like that come here to Houston — and it will be her first fan event. She's done the San Diego Comic Con, but that was more of a media event."

Both actresses also have autograph visits available for purchase. Clarke's are sold out online, but some opportunities will be made available day of.

The first ever ESPN collegiate esports competition

ESPN's inaugural esports competition for college students is premiering at Comicpalooza. Jamie McInall/Pexels

For the first time ever, ESPN is having a collegiate esports championship and chose Houston to be the place for the finals.

"We've understood the value of [esports] for Comicpalooza for a number of years. ESPN is making a big investment — it's their first ever event of this nature, but it won't be their last," Heckman says.

Students from hundreds of schools have competed to make it to the semifinals and championship in Houston, and scholarships are on the line. The weekend will have 22 teams across five video games — Hearthstone, Heroes of the Storm, Overwatch, StarCraft II, and Street Fighter V — according to ESPN. To read more about the competition, click here.

Makers on display

Anyone can check out the Comicpalooza Maker's Space — there's even a place to fix any cosplay wardrobe malfunctions. Photo via comicpalooza.com

Calling all makers — professionals or wannabes. Comicpalooza's Maker's Space is open to cosplayers, artists, engineers, scientists and everyone in between who wants to create and build using old and new technology, from small electrical parts to towering 3D printers and Lego masterpieces.

"What a lot of people don't know is there are so many interesting aspects to Comicpalooza — from literature tracks to a film festival to a makerspace," Heckman says. "There are hundreds of exhibitors on the expo showfloor, but there's an area carved out for makers."

A party on the promenade

Free concert anyone? Photo via comicpalooza.com

From 6 to 10 pm on Saturday, Avenida Houston will be transformed into an after party put on by Saint Arnold's and headlined by Icona Pop. It's free to attend, and you can get more info here.

VIPs all around

It's not just the Game of Thrones people being featured. Photos via comicpalooza.com

Comicpalooza attendees can grab photos with or autographs from over 30 different actors across major franchises — like Star Trek, Walking Dead, and so much more.

The list of actors is as follows: Emilia Clarke, Nathalie Emmanuel, Grant Gustin, Wilmer Valderrama, Dan Fogler, Gates McFadden, Michael Dorn, John Wesley Shipp, Peter Serafinowicz, Griffin Newman, Yara Martinez, Brendan Hines, Scott Speiser, Jeremy Davies, Andrew Divoff, Mira Furlan, Erick Avari and more.

Michael Heckman shares about some exciting new aspects of Houston's 11th annual Comicpalooza. Courtesy of Houston First

Comicpalooza expects another record year, says Houston First Corp. executive

Featured Innovator

Eleven years ago, Comicpalooza was a small event held out in Katy. Over the past few years, with the help of Houston First Corp., the three-day conference has grown to be so big, the 2019 programming will spill out of George R. Brown Convention Center and into Discovery Green, and attract over 50,000 attendees.

"These comic conventions used to just be for the hardcore pop culture fans. What we've attempted to do is make it so there's something for everyone," says Michael Heckman, Comicpalooza president and senior vice president at Houston First. "As a casual pop culture fan, there's a lot to see and do."

The festivities take place Friday, May 10, to Sunday, May 12, and include some big name events. Two Game of Thrones stars — Emilia Clarke (Daenerys Targaryen) and Nathalie Emmanuel (Missandei) — will be on a panel, and ESPN will host its first collegiate esports competition.

Heckman tells InnovationMap more about these big events and how Comicpalooza has transformed over the years.

InnovationMap: How the event has grown over the past decade? 

Michael Heckman: We've really worked hard to increase the impact of the event. There's a lot of out of town visitors that do come in — it has north of a $20 million economic impact every year. When you look at an event that is held during a traditionally slow period of time, it's a really big deal for the hotels and restaurants. The other part about it is when you're able to bring big stars to Houston, they're tweeting about it and posting Instagram stories about it. It does a lot to shine a spotlight on Houston's reputation and image.

IM: What are you most excited about for this year?

MH: It's a big sprawling event that takes place across all 1.2 million square feet of GRBCC. I'm excited about a few things. First, we've got the two folks from Game of Thrones. To be able to get Emilia Clarke in the middle of the final season of Game of Thrones, with only two episodes to go — the hype has been unbelievable. To be able to have a pop culture phenomenon like that come here to Houston — and it will be her first fan event. She's done the San Diego Comic Con, but that was more of a media event.

We've also got the ESPN Collegiate Esports Championship held here. We've done esports and gaming over the past few years, but it's a growth area for the event. To be able to hold that event with dozens of championships from around the country for this inaugural event is very exciting.

What a lot of people don't know is there are so many interesting aspects to Comicpalooza — from literature tracks to a film festival to a makerspace. There are hundreds of exhibitors on the expo showfloor, but there's an area carved out for makers. We have NASA, a cultural arts avenue, there's something for everyone. We're really looking forward to a blockbuster year.

IM: What did it mean for Houston to get ESPN’s collegiate esports program? 

MH: Esports is rapidly growing. That marketplace is developing very quickly. A lot of people and a lot of cities are figuring out what that means. We've understood the value of it for Comicpalooza for a number of years. ESPN is making a big investment — it's their first ever event of this nature, but it won't be their last.

IM: How did it come about?

MH: We've been talking to a number of folks across the landscape about how to best utilize the space that we have at GRBCC and find an opportunity that was a good fit for us. A couple people we were talking to out on the West Coast who connected us to the ESPN people, who happen to be the same division of ESPN that partners with the Houston Texans on a couple things. There's some synergies there, and they're familiar with Houston.

IM: How would you describe Comicpalooza's economic impact on Houston?

MH: Around 20 to 30 percent for the audience of Comicpalooza comes from outside of Houston. Last year, we had attendees from 47 states and 17 countries. It gives great exposure to the city, and the money they leave behind is valuable from an economic impact perspective. We think our numbers will be somewhat similar to last year.

If you look at the long term vision of what this could be, we have a beautiful campus for this event. We've moved some of our programming outside GRBCC onto the Avenida Plaza that connects to Discovery Green. If we have a full campus-wide event, that's something that's highly attractive. You grow that attendance, get up to 70 or 80 thousand people — that's a mega event. It's a snowball — once you get it started and then it just takes off. We're not there yet, but we've had really smart growth.

IM: How is the city as a whole preparing for the event?

MH: Houston's really good about handling events. It takes everything from the fire department to the police department and traffic control and 700 event volunteers — over 2,000 shifts. It's such a big footprint — it's kind of all hands on deck. It also looks like we'll have Astros at home and the Rockets playing game six of the playoffs at home. This major super block in downtown will be absolutely electric this weekend.

IM: What other events are you looking to bring to Houston?

MH: We'll always be chasing our conventions we have here. Our convention sales team looks to break another record this year. We have a lot of major events upcoming — from the college football playoff to the men's basketball Final Four, and we'll eventually pursue another Super Bowl. As we look to develop our portfolio of events that we manage here, there's a lot of opportunities here for events centered around innovation. There's a lot of talk around how Houston needs to have a better reputation for innovation. We've got aerospace, medical, oil and gas — what's an event we can create or partner on that could highlight Houston's innovation.

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Portions of this interview have been edited.

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Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.

Houston quantum energy chip startup emerges from stealth with $12M round

seed funding

Houston-based Casimir has emerged from stealth with a $12 million seed round to commercialize its quantum energy chip.

The round was led by Austin-based Scout Ventures. Lavrock Ventures, Cottonwood Technology, Capital Factory, American Deep Tech, and Tim Draper of Draper Associates also participated in the round. The oversubscribed round exceeded the company’s original $8 million target, according to a news release.

Casimir’s semiconductor chips can generate power from quantum vacuum fields without the need for batteries or charging. The company plans to commercialize its first-generation MicroSparc chip by 2028.

The MicroSparc chip measures 5 millimeters by 5 millimeters and is designed to produce 1.5 volts at 25 microamps, comparable to a small rechargeable battery, without degradation and no replacement cycle.

“Casimir represents exactly the kind of breakthrough dual-use technology Scout Ventures was built to back,” Brad Harrison, founder and managing partner at Scout Ventures, said in the release. “This is based on 100 years of science and we’re finally approaching a commercial product … We’re proud to lead this round and support Casimir’s journey from applied science to deployed technology.”

Casimir says it aims to scale its technology across the ”full power spectrum,” including large-scale energy systems that can power homes, commercial infrastructures and electric vehicles.

Casimir's scientific work has been supported by DARPA-funded nanofabrication research and its technology was incubated at the Limitless Space Institute (LSI). LSI is a nonprofit that works to innovate interstellar travel and was founded by Kam Ghaffarian. Technology investor and serial entrepreneur Ghaffarian has been behind companies like X-energy, Intuitive Machines, Axiom Space and Quantum Space.

Harold “Sonny” White, founder and CEO of Casimir, believes the technology can power devices for years without replacements.

“Millions of devices will operate for years without a battery ever needing to be replaced or recharged because we have engineered a customized Casimir cavity into hardware capable of producing persistent electrical power,” White added in the release. “I spent nearly two decades at NASA studying how we power humanity’s future. That work led me to the Casimir effect and the quantum vacuum, where new tools have allowed us to build on a century of scientific knowledge and bring abundant power to the world.”

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