Houston's primed to lead space innovation into the future — it's already happening here, as one panel at SXSW explains. Image via axiomspace.com

For all of the time they've been on earth, humans have looked up and wondered what was out there. Now more than ever, as a recent panel of experts discussed, humans are equipped to find out.

“We actually have, for the very first time, not just the ability to answer those questions, but to be able to go and live among the stars,” says Douglas Terrier, associate director for vision and strategy at NASA's Johnson Space Center. “It’s really a phenomenal thing to think that we are existing at this time.”

Terrier was joined by fellow panelists Matt Ondler, CTO of Axiom Space, and Tim Crain, CTO of Intuitive Machines, along with moderator Arturo Machuca, director of Houston Spaceport, to explore what has contributed to this unique moment in time for space commercialization. The panel, which was presented by Houston Spaceport and hosted by the Greater Houston Partnership, took place at Houston House at SXSW on Sunday, March 13.

An industry that was run exclusively by the government has evolved to include commercialization — and not just on a corporate level.

“We’re at this inflection point where access to space is easier — companies are emerging and it’s not just NASA and big companies like Boeing and Lockheed that can participate in space,” Ondler says.

This evolution was crucial to continue developing the technologies needed to advance the industry. Ondler's company Axiom Space is working on the first commercial space station for lower earth orbit, or LEO. This project will be 100 to 1,000 times less expensive than what it cost to build the International Space Station.

“We’re really leveraging so much history and so much of the government’s investment to build our commercial space station,” Ondler says.

The LEO economy is a trillion dollar economy — and one that has been overtaken by commercial companies, which is exactly what NASA needed to allow for it to refocus efforts to returning to the moon with its Artemis project.

“We’ve gotten over that first obstacle where we’ve commercialized operations of low earth orbit,” Terrier says. “That frees us up to look further.”

For decades, the aerospace industry has been responsible for churning out technologies that, in addition to their space application, can make a difference on earth as well.

“We spend a lot of money getting to space, but what it does is push forward all of these things we have to invent, and they find their ways into application in medicine, water purification, clean energy — all return tenfold value to our society," Terrier says on the panel.

Today, Terrier says the space economy is over $400 billion — and only a quarter of that is government investment. With this influx of companies working in space innovation, Houston has all it needs to be a leader in the field.

“Innovation and the ability to commercially engage in space requires a lot of ideas and new ways of looking of things,” Crain says, pointing out the area around the JSC and the spaceport. “The more opportunities we have for these ideas to come together and interchange, that is going to open up the capability to make commercialization successful.”

He continues saying the city is building a critical mass with space tech startups, talent within engineering and manufacturing, government support, and more.

“It’s more open now than it's ever been for both the city and for NASA to support companies who want to work in Houston,” Crain says. “When you put all those ingredients together the opportunities are really endless, and it’s the place to be.”

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.