Houston is home to a few of the highest-ranked high schools in the nation. Getty Images

Three Houston high schools are continuing their streak of top appearances on a prestigious annual list of the country's best public high schools.

The 2023 rankings from U.S. News & World Report, released August 29, put Houston ISD’s Carnegie Vanguard High School at No. 35 nationally (up from No. 40 last year) among the country’s best high schools. The school also ranks No. 248 nationally among the best STEM (science, technology, engineering, and math) high schools and No. 12 among the best magnet high schools.

Also in the top 100 are two other Houston ISD high schools.

DeBakey High School for Health Professions ranks No. 66 nationally among the best high schools (down from No. 50 last year) and No. 18 among best magnet high schools for the second consecutive year.

Young Women's College Prep Academy comes in No. 94 nationally among the best high schools (up from No. 148 last year), and No. 26 among best magnet high schools.

Topping the national list for 2023 is the Early College at Guilford in Greensboro, North Carolina.

Each year, U.S. News evaluates about 18,000 high schools on six factors: college readiness, reading and proficiency, reading and math performance, underserved student performance, college curriculum breadth, and graduation rates.

"Having access to a strong high school program is paramount for students as they face an ever-changing world," said U.S. News' managing editor of education Liana Loewus in a release. "Making data on our high schools available helps parents ensure their child is in the educational environment that best sets them up to thrive."

Elsewhere in Texas
Around the state, these Texas high schools also made it into the top 100 nationally:

  • Dallas ISD's The School for the Talented and Gifted, No. 6 (up from No. 8 last year and No. 13 in 2021). No. 8 nationally among the best STEM high schools for the second consecutive year and No. 2 among the best magnet high schools (up from No. 4 last year).
  • Dallas ISD's Irma Lerma Rangel Young Women's Leadership School, No. 18 (up from No. 20 last year) and No. 8 nationally among the best magnet high schools for the second consecutive year.
  • Dallas ISD's Science and Engineering Magnet School, No. 23 nationally among the best high schools (down from No. 22 last year), No. 24 nationally among the best STEM high schools (down from No. 7 last year), and No. 2 nationally among the best magnet high schools (up from No. 10 in 2022).
  • Austin ISD’s Liberal Arts and Science Academy, No. 32 (up from No. 34 last year and No. 41 in 2021). No. 34 nationally among the best STEM high schools (up from No. 70 in 2022).
  • BASIS San Antonio - Shavano Campus, No. 81 (down from No. 77 last year and No. 102 in 2021). No. 41 nationally among the best STEM high schools (down from No. 25 in 2022) and No. 17 nationally among the best charter high schools.
  • Dallas ISD's Trinidad Garza Early College at Mt. View, No. 91 (up from No. 118 last year).
  • Dallas ISD’s Judge Barefoot Sanders Law Magnet, No. 93 (down from No. 48 last year and No. 59 in 2021) . No. 25 nationally among the best magnet high schools (down from No. 17 in 2022).
  • Austin ISD's Richards School for Young Women Leaders, No. 95 (up from No. 128 last year).

When broken down just to Texas schools, Houston's Carnegie Vanguard High School (No. 5), DeBakey High School for Health Professions (No. 6), and Young Women's College Prep Academy (No. 10) are all in the top 10 best-rated public high schools in Texas this year, U.S. News says.

Other Houston-area schools that rank among Texas' 100 best are:

  • No. 12 – Kinder High School for Performing and Visual Arts, Houston ISD
  • No. 21 – Challenge Early College High School, Houston ISD
  • No. 24 – Kerr High School, Alief ISD, Houston
  • No. 29 – Eastwood Academy, Houston ISD
  • No. 37 – YES Prep - Southwest, Houston
  • No. 39 – Harmony School of Innovation - Katy, Katy
  • No. 40 – North Houston Early College High School, Houston ISD
  • No. 42 – Clear Horizons Early College High School, Clear Creek ISD, Houston
  • No. 46 – Seven Lakes High School, Katy ISD
  • No. 53 – Victory Early College High School, Aldine ISD, Houston
  • No. 54 – YES Prep - Southeast, Houston
  • No. 57 – East Early College High School, Houston ISD
  • No. 58 – Houston Academy for International Studies, Houston ISD
  • No. 64 – YES Prep - East End, Houston
  • No. 69 – Tomball Star Academy, Tomball ISD
  • No. 72 – Early College Academy at Southridge, Spring ISD, Houston
  • No. 73 – Tompkins High School, Katy ISD
  • No. 75 – Clements High School, Fort Bend ISD, Sugar Land
  • No. 82 – YES Prep - North Central, Houston
  • No. 83 – Sharpstown International School, Houston ISD
  • No. 93 – YES Prep - North Forest, Houston
  • No. 95 – YES Prep - West, Houston
  • No. 97 – High School for Law and Justice, Houston ISD

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This article originally ran on CultureMap.

DeBakey High School for Health Professions is at the top of the class. Photo by skynesher/Getty Images

Houston STEM high school declared top of the class by U.S. News & World Report

A-plus

Three Houston high schools deserve a tip of the cap (or mortarboard) after earning marks for excellence. On June 12, U.S. News & World Report released its annual Best U.S. High Schools by metro area, ranking the top public schools in each major city.

DeBakey High School for Health Professions is at the top of the class in the Bayou City. In addition to earning top marks for academics, the school is notably comprised of mostly minority students — 89 percent.

To determine the country's best schools, U.S. News ranked each school using six metrics, applying different weights to each category:

  • College readiness (30 percent)
  • Math and reading proficiency (20 percent)
  • Math and reading performance (20 percent)
  • Underserved service (10 percent)
  • College curriculum breadth (10 percent)
  • Graduation rate (10 percent)

Based on the above, the school has an overall score of 99.9 (or an A-plus in high school lingo), complete with 100 percent graduation and reading and mathematics proficiency rates. Also, 100 percent of students took and passed at least one AP exam.

Located on the prestigious Texas Medical Center Campus, DeBakey offers students unparalleled access to on-site research facilities, as well as future academic opportunities, U.S. News notes.

"Graduates are eligible for the Houston Premedical Academy, an undergraduate program at the University of Houston designed specifically for DeBakey High School students," the report says. "Those selected for the premedical academy receive provisional acceptance to the Baylor College of Medicine."

DeBakey ranks first in Houston and No. 17 nationally. The school is also rated No. 10 in the U.S. among magnet schools and No. 11 among STEM schools.

Carnegie Vanguard High School earned the No. 2 spot in Houston, 24th in the nation, followed by Eastwood Academy at No. 3 locally and 97th nationally.

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A version of this story, with information on Texas' other metros, originally was published on CultureMap.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”