Gensler is using a new software program to help optimize social distancing in the workplace for Houston companies returning to the office. Photo courtesy of Gensler

The COVID-19 pandemic has displaced many Houstonians from their office jobs to makeshift work-from-home setups. With coronavirus cases climbing in Houston, the obstacle of returning to work safely is undoubtedly on the minds of business owners across the city.

Thankfully, there's an algorithm for that. Gensler, a global architecture firm, has unveiled its ReRun program as a pandemic response tool to help offices create workspace layouts for safe social distancing.

ReRun allows Gensler to upload a floorplan into the program, which applies generative algorithms to determine safe separation between workplaces by creating circles ranging from six to eight-foot diameters. The tool can quickly generate scenarios and identify the most optimized capacity to meet social distancing demands, easing the role of operations and human resources.

"It's really just a tip of the spear in terms of occupancy planning, because once you know that information, then the next question is what do I do with that?" says Dean Strombom, strategy lead and principal at Gensler's Houston office.

"ReRun is the first tool we utilize to help [clients] determine how many people might be able to come back and still achieve the social distancing side. Then we work with them on how they should come back, whether it's a percentage of employees, staggered shift work or alternating days," Strombom says. Circulation patterns are also taken into account by the Gensler team, who analyze the traffic of hallways, meeting spaces and lounge areas.

Dean Strombom is the strategy lead and principal at Gensler's Houston office. Photo courtesy of Gensler

The international firm, with 50 offices around the world, has rolled out the ReRun tool to its database of clientele. The platform is also available to businesses outside of the firm's existing portfolio, who can use the tool by providing a simple CAD design of their workplace. ReRun is applied through the company's SaaS space management software, Wisp. Using occupancy planning, Wisp provides clients with color-coded floor plans to help visualize and communicate to their teams which seats are available or assigned for occupancy as employees phase back into the office.

The response has been positive among clientele. Strombom is currently applying Gensler's social distancing tool with a large financial services company with locations throughout the Houston area.

"We are loading the information from ReRun into the Wisp program, and then we'll be helping them determine how they will return to work, and specifically where people will sit," he shares. The company plans to come back with 20 percent of the workforce, increasing overtime with the help of Gensler's team. "Who comes back when and specifically where is what they're most excited about."

The company has determined four work modes employees exhibit: focus, collaboration, socialization, and learning. By categorizing the work modes, Gensler is looking ahead at how interior architecture can accommodate these phases.

"More recently, we've been talking about a need for regenerative spaces so that people can become more engaged in the workplace," says Strombom.

As described in a Gensler blog, isolation rooms were optioned as a way to contain an employee who begins to feel symptomatic but these rooms can also serve a different purpose for employees acclimating to a new normal.

"The isolation room is what we often call a wellness room in an office where people can get away from the general tensions that they may be feeling in a workplace where they can relax and reinvigorate themselves in a quiet space," says Strombom.

As the architecture industry adjusts to a post-pandemic world, Gensler is working with developer clients and building owners to share the near-term and long-term changes the company foresees. Strombom says clients have flexibility as a priority.

ReRun allows Gensler to upload a floorplan into the program, which applies generative algorithms to determine safe separation between workplaces by creating circles ranging from six to eight-foot diameters. Graphic courtesy of Gensler

"We have to think about the entire path or the entire entry sequence in office buildings that is true for residential as well. From the moment that you pull into the garage, what are all of those points along the way where you've got to be concerned about contact and cleanliness?" Strombom shares.

Strombom foresees new building systems coming to the forefront, for example air conditioners with a focus on keeping clean air circulation within the office building. He also predicts a need for flexible spaces that can change depending on the circumstances.

"You hear a lot about temperature readings and separations of people within building lobbies during pandemics. We need systems in place that you can rapidly deploy when something like this happens, but the majority of the time it can revert to a more normal circumstance," he says.

Tight spaces also require a new way of thinking.

"We've realized that the elevator cab is really one of the pinch points in office buildings if you're trying to maintain this social distancing," Strombom shares. "There's technology [out there] that can identify how many people are going to be entering a cab and restrict that occupancy. So that is something that's going to need to be done for the near term."

In a Gensler survey of its Houston office, 72 percent of respondents expect a maintained or increased level of virtual collaboration compared to these pre-COVID levels.

"As people have been semi-forced to work at home, they've realized that not only is it possible, but for some people it's the preferred way to work," says Strombom, who predicts virtual meetings will continue on.

While platforms like Zoom and Skype make meetings tenable, company employees are still anticipating a future in the office.

"Those of us that are now working from home, if you ask people the majority of respondents to the question of what they miss most, it's really the people," Strombom says.

From common space to desks and offices, ReRun can help enable social distancing in the workplace. Photo courtesy of Gensler

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."