Gensler is using a new software program to help optimize social distancing in the workplace for Houston companies returning to the office. Photo courtesy of Gensler

The COVID-19 pandemic has displaced many Houstonians from their office jobs to makeshift work-from-home setups. With coronavirus cases climbing in Houston, the obstacle of returning to work safely is undoubtedly on the minds of business owners across the city.

Thankfully, there's an algorithm for that. Gensler, a global architecture firm, has unveiled its ReRun program as a pandemic response tool to help offices create workspace layouts for safe social distancing.

ReRun allows Gensler to upload a floorplan into the program, which applies generative algorithms to determine safe separation between workplaces by creating circles ranging from six to eight-foot diameters. The tool can quickly generate scenarios and identify the most optimized capacity to meet social distancing demands, easing the role of operations and human resources.

"It's really just a tip of the spear in terms of occupancy planning, because once you know that information, then the next question is what do I do with that?" says Dean Strombom, strategy lead and principal at Gensler's Houston office.

"ReRun is the first tool we utilize to help [clients] determine how many people might be able to come back and still achieve the social distancing side. Then we work with them on how they should come back, whether it's a percentage of employees, staggered shift work or alternating days," Strombom says. Circulation patterns are also taken into account by the Gensler team, who analyze the traffic of hallways, meeting spaces and lounge areas.

Dean Strombom is the strategy lead and principal at Gensler's Houston office. Photo courtesy of Gensler

The international firm, with 50 offices around the world, has rolled out the ReRun tool to its database of clientele. The platform is also available to businesses outside of the firm's existing portfolio, who can use the tool by providing a simple CAD design of their workplace. ReRun is applied through the company's SaaS space management software, Wisp. Using occupancy planning, Wisp provides clients with color-coded floor plans to help visualize and communicate to their teams which seats are available or assigned for occupancy as employees phase back into the office.

The response has been positive among clientele. Strombom is currently applying Gensler's social distancing tool with a large financial services company with locations throughout the Houston area.

"We are loading the information from ReRun into the Wisp program, and then we'll be helping them determine how they will return to work, and specifically where people will sit," he shares. The company plans to come back with 20 percent of the workforce, increasing overtime with the help of Gensler's team. "Who comes back when and specifically where is what they're most excited about."

The company has determined four work modes employees exhibit: focus, collaboration, socialization, and learning. By categorizing the work modes, Gensler is looking ahead at how interior architecture can accommodate these phases.

"More recently, we've been talking about a need for regenerative spaces so that people can become more engaged in the workplace," says Strombom.

As described in a Gensler blog, isolation rooms were optioned as a way to contain an employee who begins to feel symptomatic but these rooms can also serve a different purpose for employees acclimating to a new normal.

"The isolation room is what we often call a wellness room in an office where people can get away from the general tensions that they may be feeling in a workplace where they can relax and reinvigorate themselves in a quiet space," says Strombom.

As the architecture industry adjusts to a post-pandemic world, Gensler is working with developer clients and building owners to share the near-term and long-term changes the company foresees. Strombom says clients have flexibility as a priority.

ReRun allows Gensler to upload a floorplan into the program, which applies generative algorithms to determine safe separation between workplaces by creating circles ranging from six to eight-foot diameters. Graphic courtesy of Gensler

"We have to think about the entire path or the entire entry sequence in office buildings that is true for residential as well. From the moment that you pull into the garage, what are all of those points along the way where you've got to be concerned about contact and cleanliness?" Strombom shares.

Strombom foresees new building systems coming to the forefront, for example air conditioners with a focus on keeping clean air circulation within the office building. He also predicts a need for flexible spaces that can change depending on the circumstances.

"You hear a lot about temperature readings and separations of people within building lobbies during pandemics. We need systems in place that you can rapidly deploy when something like this happens, but the majority of the time it can revert to a more normal circumstance," he says.

Tight spaces also require a new way of thinking.

"We've realized that the elevator cab is really one of the pinch points in office buildings if you're trying to maintain this social distancing," Strombom shares. "There's technology [out there] that can identify how many people are going to be entering a cab and restrict that occupancy. So that is something that's going to need to be done for the near term."

In a Gensler survey of its Houston office, 72 percent of respondents expect a maintained or increased level of virtual collaboration compared to these pre-COVID levels.

"As people have been semi-forced to work at home, they've realized that not only is it possible, but for some people it's the preferred way to work," says Strombom, who predicts virtual meetings will continue on.

While platforms like Zoom and Skype make meetings tenable, company employees are still anticipating a future in the office.

"Those of us that are now working from home, if you ask people the majority of respondents to the question of what they miss most, it's really the people," Strombom says.

From common space to desks and offices, ReRun can help enable social distancing in the workplace. Photo courtesy of Gensler

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Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

5+ must-know application deadlines for Houston innovators

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Editor's note: As 2026 ramps up, the Houston innovation scene is looking for the latest groups of innovative startups that'll make an impact. A number of accelerators and competitions have opened applications. Read below to see which might be a good fit for you or your venture. And take careful note of the deadlines. Please note: this article may be updated to include additional information and programs.

Did we miss an accelerator or competition accepting applications? Email innoeditor@innovationmap.com for editorial consideration.

2026 HCC Business Plan Competition

Deadline: Jan. 26

Details: HCC’s annual Business Plan Competition (BPC) is an opportunity for proposed, startup and existing entrepreneurs to develop focused plans to start or grow their businesses. Accepted teams will be announced and training will begin in late February and run through early June, with six free, three-hour training sessions. Advising will be provided to each accepted team. Applicants can apply as a team of up to five persons. Finalists will present to to gudges on May 27, 2026. Last year, $26,000 was awarded in seed money to the top five teams. In-kind prizes were also awarded to all graduating teams including free products, services and memberships, with an estimated in-kind value totaling $147,000. Find more information here.

University of Houston Technology Bridge Innov8 Hub (Spring 2026)

Deadline: Jan . 30

Details: UHTB Innov8 Hub’s immersive, 12-week startup acceleration program designed to help early-stage founders launch and scale their technology startups. Selected participants will gain access to expert mentors and advisors, collaborate with a cohort of peers, and compete for cash prizes during our final pitch event. The cohort begins Feb. 16, 2026. The program culminates in Pitch Day, where participants present their ventures to an audience of investors and partners from across the UH innovation ecosystem. Find more information here.

Rice Business Plan Competition 2026

Deadline: Jan. 31

Details: The Rice Business Plan Competition, hosted by the Rice Alliance for Technology and Entrepreneurship, gives collegiate entrepreneurs real-world experience to pitch their startups, enhance their business strategy and learn what it takes to launch a successful company. Forty-two teams will compete for more than $1 million in cash, investments and prizes on April 9-11, 2026. Find more information here.

Rice Veterans Business Battle 2026

Deadline: Jan. 31

Details: The Rice Veterans Business Battle is one of the nation’s largest pitch competitions for veteran-led startups, providing founders with mentorship, exposure to investors and the opportunity to compete for non-dilutive cash prizes. The event has led to more than $10 million of investments since it began in 2015. Teams will compete April 8-9, 2026. Find more information here.

TEX-E Fellows Application 2026-2027

Deadline: Feb. 10

Details: The TEX‑E Fellowship is a hands-on program designed for students interested in energy, climate, and entrepreneurship across Texas. It connects participants with industry mentors, startup founders, investors and academic leaders while providing practical, "real-world" experience in customer discovery, business modeling, and energy-transition innovation. Fellows gain access to workshops, real-world projects, and a statewide network shaping the future of energy and climate solutions. Participants must be a student at PVAMU, UH, UT Austin, Rice University, MIT or Texas A&M. Find more information here.

2026 Energy Venture Day & Pitch Competition

Deadline: Feb. 13

Details: The Rice Alliance, the Houston Energy Transition Initiative (HETI) and TEX-E will present the annual Energy Venture Day and Pitch Competition during CERAWeek on March 24-25, 2026. Energy Venture Day features two days of presentations by energy tech ventures driving efficiency and advancements toward the energy transition. On March 24, the Pitch Preview at the Ion will feature over 50 companies presenting in front of Rice Alliance's robust network of investors and industry partners. On March 25, the Energy Venture Day and Pitch Competition during CERAWeek will showcase 36 ventures at the George R Brown Convention Center. The pitch competition is divided up into the TEX-E university track, in which Texas student-led energy startups compete for $50,000 in cash prizes, and the industry ventures track. The industry track is subdivided into three additional tracks, spanning materials to clean energy. The top three companies from each industry track will be named. The winner of the CERAWeek competition will also have the chance to advance and compete for the $1 million investment prize at the Startup World Cup. Find more information here.

Greentown Go Make 2026

Deadline: March 10

Details: Greentown Go Make 2026 is an open-innovation program with Shell and Technip Energies. The six-month program is advancing industrial decarbonization by accelerating catalytic innovations. Selected startups will gain access to a structured platform to engage leadership from Shell and Technip Energies and explore potential partnership outcomes, including pilots and demonstrations. They’ll also receive networking opportunities, partnership-focused programming, and marketing visibility throughout the program. The cohort will be selected in May. Find more information here.