Kevin Knobloch is stepping down as Greentown Labs CEO, effective on July 31. Photo via LinkedIn

Greentown Labs, which is co-located in the Boston and Houston areas, has announced its current CEO is stepping down after less than a year in the position.

The nonprofit's CEO and President Kevin Knobloch announced that he will be stepping down at the end of July 2024. Knobloch assumed his role last September, previously serving as chief of staff of the United States Department of Energy in President Barack Obama’s second term.

“It has been an honor to lead this incredible team and organization, and a true privilege to get to know many of our brilliant startup founders," Knobloch says in the news release. “Greentown is a proven leader in supporting early-stage climatetech companies and I can’t wait to see all that it will accomplish in the coming years.”

The news of Knobloch's departure comes just over a month after the organization announced that it was eliminating 30 percent of its staff, which affected 12 roles in Boston and six in Houston.

According the Greentown, its board of directors is expected to launch a national search for its next CEO.

“On behalf of the entire Board of Directors, I want to thank Kevin for his efforts to strengthen the foundation of Greentown Labs and for charting the next chapter for the organization through a strategic refresh process,” says Dawn James, Greentown Labs Board Chair, in the release. “His thoughtful leadership will leave a lasting impact on the team and community for years to come.”

Knobloch reportedly shifted Greentown's sponsorship relationships with oil companies, sparking "friction within the organization," according to the Houston Chronicle, which also reported that Knobloch said he intends to return to his clean energy consulting firm.

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This article originally ran on EnergyCapital.

Kevin Knobloch will lead Greentown Labs as CEO. Photo via LinkedIn

Greentown Labs names new CEO to oversee Houston, Boston incubators

seeing green

The largest climatetech incubator in North America has named an Obama Administration appointee as its next CEO.

Kevin Knobloch, who served as chief of staff of the United States Department of Energy in President Barack Obama’s second term, will be CEO of Greentown Labs, effective September 5. In his role, Knobloch will oversee both Greentown locations in Houston and Somerville, Massachusetts, outside of Boston.

“Kevin has a proven and impressive track record of growing, operationalizing, and leading a dynamic mix of organizations at different stages and in various industries, all of which have aligned with his unwavering commitment to addressing the climate crisis,” Greentown Labs Board Chair Dawn James says in a news release. “On behalf of the entire Board of Directors, I am thrilled to welcome Kevin as our next CEO. We are excited for what is to come under Kevin’s leadership and look forward to the positive impact he will undoubtedly have on our team, our startup community, and the ecosystem at large.”

With 30 years of experience across sectors, Knobloch most recently served as president of Knobloch Energy, an independent advisory and consulting firm. He also served as acting executive director of the National Offshore Wind Research & Development Consortium from June through December 2022. From 2018 to 2020, Knobloch was president of New York OceanGrid LLC, where he led Anbaric’s efforts to develop offshore wind transmission in New York.

“I’m honored and thrilled to have the opportunity to once again pass the leadership baton,” Greentown Co-Founder Jason Hanna says, who has been serving as interim CEO. “Especially so given Kevin’s incredible record of climate leadership. I’m excited for the future of this organization and the impact he can make as Greentown enters the second decade of its climate mission.”

The appointment follows an executive search that began after Greentown's previous CEO Emily Reichert announced she was stepping down in December.

“I’m delighted to be asked by Greentown Labs’ Board of Directors to be the next leader of this highly effective organization—and very excited to get to work,” Knobloch says in a statement. “I’ve long admired the critical role Greentown plays in supporting the growth and impact of early-stage climate and energy transition technology companies, as well as the impressive efforts by former longtime CEO Emily Reichert and the talented Board and staff to build Greentown into a national powerhouse and model for other incubators around the world. The climate crisis demands that we accelerate our collective pace of deployment and I look forward to collaborating with our startups, staff, and partners to support that acceleration.”

The announcement comes on the heels of Greentown naming its inaugural Houston general manager. Timmeko Moore Love was named to that new position last week.

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Houston digital health platform Koda lands strategic investment

money moves

Houston-based advance care planning platform Koda Health has added another investor to the lineup.

The company secured a strategic investment for an undisclosed amount from UPMC Enterprises, the commercialization arm of the University of Pittsburgh Medical Center. The funding is part of Koda's oversubscribed series A funding round that closed in October, according to a release.

"UPMC Enterprises’ investment is a meaningful signal, not just to Koda, but to the broader market," Dr. Desh Mohan, chief medical officer and co-founder of Koda Health, said in the news release. "It validates that health systems are ready to invest in infrastructure that makes advance care planning work the way it should: proactively, at scale, and with the human support that these conversations require. Having UPMC Enterprises as a strategic investor puts us in a unique position to prove what's possible."

Koda has raised $14 million to date, according to a representative from the company. Its series A round was led by Evidenced, with participation from Mudita Venture Partners, Techstars and the Texas Medical Center last year. At the time, the company said the funding would allow it to scale operations and expand engineering, clinical strategy and customer success. The company described the round as a "pivotal moment," as it had secured investments from influential leaders in the healthcare and venture capital space.

Koda Health, which was born out of the TMC's Biodesign Fellowship in 2020, saw major growth last year, as well, and now supports more than 1 million patients nationwide through partnerships with Cigna Healthcare, Privia Health, Guidehealth, Sentara, UPMC and Memorial Hermann Health System.

The company integrated its end-of-life care planning platform with Dallas-based Guidehealth in April 2025 and with Epic Systems in July 2025. It also won the 2025 Houston Innovation Award in the Health Tech Business category. Read more here.

New 'living pharmacy' biotech company launches out of Rice venture studio

fighting cancer

Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”