This week's roundup of Houston innovators includes Ody De La Paz of Sensytec, Sassie Duggleby of Venus Aerospace, and David Eagleman. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from aerospace to nueroscience — recently making headlines in Houston innovation.

Ody De La Paz, CEO and co-founder of Sensytec

Ody De La Paz, CEO and founder of Sensytec, joins the Houston Innovators Podcast to discuss the future of his company as it gears up for growth. Photo courtesy of Sensytec

The importance of creating longer lasting infrastructure is top of mind for the country, and Ody De La Paz, co-founder and CEO of Sensytec, is prepared to help. Through participation in AFWERX — the innovation arm of the Air Force, construction tech company Sensytec was tapped by the military to use the technology across operations.

"The plan is to integrate our system and analytics from sensors into a multi-platform system that the Air Force is trying to roll out in all of the military bases," De La Paz says on last week's episode of the Houston Innovators Podcast. "We're trying to be that center hub for concrete and soil monitoring for them."

With the passing of the Infrastructure Investment and Jobs Act, $65 billion is being deployed to build or improve infrastructure — among other tech and transportation improvements — and a lot of that funding is coming to the Lone Star State. De La Paz discusses more on the podcast. Click here to read more and stream the episode.

Sarah "Sassie" Duggleby, co-founder and CEO of Venus Aerospace

Houston-based Venus Aerospace has raised $20 million — and is one step closer to providing one-hour global travel. Photo courtesy of Venus Aerospace

A Houston aerospace startup has raised millions to continue its work on a zero-carbon emission spaceplane that will enable one-hour global travel. Venus Aerospace closed its $20 million series A funding round led by Wyoming-based Prime Movers Lab.

"We are excited to continue our partnership with Prime Movers Lab and our other great investors. In the past year, with our initial funding, we have scaled from 3 people to 40. These are the world's best rocket scientists, engineers, and operators," says Sassie Duggleby in the release. "With this funding, we will continue to push forward toward our next technical milestones, hire great people, and scale our organization. We are excited to continue engineering the future of high-speed aviation." Click here to read more.

David Eagleman, author and neuroscientist 

David Eagleman returns to Houston this month. David Eagleman/Facebook

Not many researchers have ever compared brain function to drug dealers, but then, not many researchers are David Eagleman. Much like charismatic astronomer Neil deGrasse Tyson, Eagleman brings hefty and brainy topics to a conversational and digestible level.

The globally renowned neuroscientist, TV host, and best-selling author will visit Houston to discuss his latest book, Livewired: The Inside Story of the Ever-Changing Brain. The event is produced by The Progressive Forum and will take place at Congregation Emanu El (1500 Sunset Blvd.) at 7:30 pm Thursday, April 28. Click here to continue reading.

David Eagleman returns to Houston this month. David Eagleman/Facebook

Brainy PBS host and celebrity author visits Houston for mindful event

wise guy

Not many researchers have ever compared brain function to drug dealers, but then, not many researchers are David Eagleman. Much like charismatic astronomer Neil deGrasse Tyson, Eagleman brings hefty and brainy topics to a conversational and digestible level.

The globally renowned neuroscientist, TV host, and best-selling author will visit Houston to discuss his latest book, Livewired: The Inside Story of the Ever-Changing Brain. The event is produced by The Progressive Forum and will take place at Congregation Emanu El (1500 Sunset Blvd.) at 7:30 pm Thursday, April 28.

Tickets are available online or by calling 800-514-3849 and also at the door on event night. General admission tickets range from $45 and $70; reserved seats and speaker reception are $150. All ticket purchases include a free copy of Livewired.

This is a homecoming of sorts for Eagleman, who attended Rice University and Baylor College of Medicine. Since then, he has become a leading — if not the preeminent — voice on all things brain and neuroscience, covering sensory substitution, time perception, vision, synesthesia, and even the intersection of neuroscience with the legal system — a task he undertakes with the University of Houston.

He is perhaps most recognizable as host and writer of the PBS and BBC television series The Brain, which has been nominated for an Emmy. Penning books The Runaway Species, The Brain, Incognito, and Wednesday is Indigo Blue, Eagleman has written a bestselling fiction, Sum, which has been translated into 32 languages, turned into two operas, and named a Best Book of the Year by Barnes and Noble.

Eagleman also pens pieces for myriad publications and frequently appears on national radio and TV programs and has hosted a TED Talk.

His lab has launched several companies, including Neosensory, a firm that uses haptics for sensory substitution and addition, according to his bio.

“The Progressive Forum is pleased to welcome a great mind with Houston roots,” said Randall Morton, its president, in a statement. “As an undergraduate at Rice, he majored in British and American literature, then earned his PhD in neuroscience at Baylor College of Medicine.”

David Eagleman will appear at Congregation Emanu El, 1500 Sunset Blvd. at 7:30 pm Thursday, April 28. For tickets and more information, visit The Progressive Forum.

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This article originally ran on CultureMap.

BrainCheck has raised its latest round of funding. Photo by Natalie Harms/InnovationMap

Houston health tech startup closes $10M series B led by Austin investors

money moves

A Houston-based tech company that's tackling cognitive health diagnoses with its innovative platform has closed its latest round of funding.

BrainCheck, the cognitive health care platform for physicians, announced the closing of its $10 million series B funding led by Austin-based investors, Next Coast Ventures and S3 Ventures. The funding will be used to expand research and development, including developing a digital therapeutic and enhancing go-to-market capabilities.

BrainCheck's digital platform allows physicians to better assess cognitive function in their patients — whether they are elderly dementia patients or suffering from other cognitive ailments. One in nine adults aged 45 and older report subjective cognitive decline, according to a news release, and one in 14 COVID-19 survivors have neurocognitive disorder.

"We are at the forefront of improving access to cognitive assessment and care," says Yael Katz, co-founder and CEO of BrainCheck, in the release. "With early diagnosis comes treatment and intervention. These funds will allow us to accelerate the adoption of our platform and work with clinicians to help more patients live better and safer lives, decrease caregiver frustration, and save health systems trillions of dollars. I believe that BrainCheck can help cognitive care evolve the way cancer care has since the 1970s, when chemotherapy was one-size-fits-all."

Katz co-founded the company with neuroscientist David Eagleman in January of 2015. Now, doctors at over 400 neurology, primary care and geriatrics practices — such as Cleveland Clinic, MD Anderson, and Johns Hopkins — are already using BrainCheck's 10-to-15-minute test, which is covered by Medicare and by most private insurers, to conduct cognitive testing. The FDA Class II Software as a Medical Device (SaMD), which means that physicians can facilitate in-person or even an remote assessment of their patients' cognitive function.

"BrainCheck is a breakthrough platform that has the potential to transform how we diagnose and treat cognitive impairment," says Michael Smerklo, co-founder and managing director of Next Coast Ventures, in the release. "The combination of technical sophistication and ease of use makes BrainCheck a perfect tool for doctors and health systems everywhere. I'm so impressed by what Dr. Katz and her team have achieved to date and am excited to support the team as they continue to innovate and scale."

Other investors included Nueterra Capital, Tensility Ventures, and True Wealth Ventures, as well as UPMC Enterprises and SelectQuote, which joined on as strategic investors.

"BrainCheck shows promise as a cognitive assessment tool that would allow patients to independently complete the test while allowing physicians to spend more time reviewing the results and planning care with patients," says Dr. Adele Towers, director of risk adjustment at UPMC Enterprises and a geriatric medicine specialist at UPMC, in the release.

BrainCheck closed its $8 million series A round in October of 2019, and the company moved into its new office in Upper Kirby following the raise in early 2020. The startup also has an office in Austin.

Amazon has selected eight KIPP schools in Houston to received resources to create robotics programs. Courtesy of Amazon

Energy tech company closes round, hospital introduces VR brain tours, Amazon bets on Houston schools, and more innovation news

Short stories

From virtual reality-enabled brain scans to Amazon selecting Houston schools for its robotics program, the future is now with this latest batch of local innovation news.

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OAG Analytics closes round

Luther Birdzell, founder and CEO of Houston-based OAG Analytics is on a mission to democratize data for his upstream oil and gas clients. Courtesy of OAG Analytics

OAG Analytics, which uses artificial intelligence in the oil and gas industry, has closed its second round of strategic funding in nine months from Rice Investment Group. The capital will be used to grow the company and focus on several major enhancements to their upstream AI platform, according to a news release.

The exact amount of the raise was not disclosed by OAG, but according to a Form D filing, the company expressed that it was raising $8.72 million in this round.

"Our industry is entering the next phase of the shale revolution by moving to full-field development. As such, we need the next generation of analytical capabilities to maximize capital efficiency," says Derek Rice, partner at Rice Investment Group and director at OAG, in a release. "Large-scale development optimization requires an in-depth understanding of hundreds of uncorrelated data points, which OAG provides through data management and advanced analytics to support profitable decision making. We are thrilled to partner with OAG's team, and believe our insights and experience as an operator will continue to add value to the platform."

OAG's founder and CEO, Luther Birdzell, created a way where he can give clients an easy-to-use platform to have access to data that could save oil and gas companies millions of dollars. In fact, according to the release, OAG clients have optimized over $10 billion in capital expenditures.

"RIG's trust in the OAG team and AI platform is a huge vote of confidence," says Birdzell in the release. "As a leadership team that already built and sold a highly data-driven, technology-centric oil and gas company, RIG's market insights and capital are important to our business. We look forward to continued collaboration as we accelerate our growth."

Methodist Hospital has new VR technology for brain treatment

Patients about to undergo brain surgery can use VR to see what their surgeon is about to do to their brain. Courtesy of Methodist

Houston Methodist Hospital is channeling a Magic School Bus episode with new VR technology that allows neurosurgical patients and their family members to essentially walk through their brains ahead of their surgeries.

The patient wears a virtual reality headset and gets a 360 degree view of their brain, and the neurosurgeon can walk the patient through the surgery process. According to a release from Houston Methodist, the technology is the first of its kind that combines fighter jet flight simulation with patients' anatomy scans from MRI, CT, and/or DTI processes to make a 3D model.

Eight Houston schools named in Amazon Future Engineer Robotics Grant program

Eight Houston schools will receive resources from Amazon to create a robotics team. Courtesy of Amazon

Eight Houston schools have been selected as part of Amazon Future Engineer Robotics Grant program. The program has selected 100 schools in 21 states and each will receive support to create robotics team and a $10,000 grant. These Houston schools were selected:

  • KIPP Academy MS
  • KIPP Connect HS
  • KIPP Connect Middle School
  • KIPP Generations Collegiate
  • KIPP Northeast College Preparatory
  • KIPP NEXUS MS• KIPP Polaris
  • KIPP Sunnyside HS

The Amazon Future Engineer program launched in November, and, according to a news release, is a four-part childhood-to-career program geared at teaching technology and computer science to children from underrepresented and underserved communities. Through the program, Amazon hopes to help more than 10 million students nationwide.

Mattress Firm seeks second round of "snoozeterns"

Last summer, Mattress Firm introduced its Snoozetern program, advertising as a "dream job" for college students wanting to get "paid to sleep." The program is looking for it's next employee that will learn the ins and outs of the Houston company and test and review products. Applications are open now until May 3. To apply or learn more, visit here.

Deloitte’s 2019 Technology Fast 500 Awards are now open

Houston companies can enter to win this national recognition from Deloitte. Photo via Deloite.com

Deloitte has opened its 2019 Technology Fast 500 Awards applications. The national awards program has been honoring fast-growing tech companies for 25 years. Last year, two Houston companies were ranked: Onit and symplr. The honorees are chosen based on the past three years' of fiscal-year revenue growth over a three-year period. Applications close on June 28. Click here for more.

The Kidney Cancer Association approves $1.3 million for early detection and new treatments

Applicants have until May 20 to submit for a grant from the Kidney Cancer Association. Photo via Facebook

The Kidney Cancer Association's board of directors approved $1.3 million to be dedicated to advancing early detection and new treatments for kidney cancer. Grant applications opened April 17 and close May 20. Grant recipients will be announced in the fall.

"The KCA Board of Directors is committed to providing research funding with the goal of identifying new treatments and finding new ways to prevent and manage the disease," says Christopher Wood, board president, in a news release. "With these advancements in research and a greater understanding of these cancers, we believe the outcomes of these grants will have substantive impact for kidney cancer patients."

There will be six grants are divided into two types of awards. The Advanced Discovery Awards will honor two "established investigators" $500,000 grants, and the Young Investigator Awards will give out four $75,000 grants.

Houston neuroscientist David Eagleman to discuss new book at the Hobby Center

Courtesy images

The Barbara Bush Houston Literacy Foundation, a Houston-based nonprofit, is hosting its 25th annual A Celebration of Reading event on Thursday, May 2, at The Hobby Center for the Performing Arts. The event hosts five authors, and this year, Houston neuroscientist David Eagleman is on the lineup.

Eagleman's most recent book, The Runaway Species: How Human Creativity Remakes the World, will be the topic of discussion during his presentation. Eagleman and his co-author, Anthony Brandt, seek to determine the human mind's ability and drive to create.

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Rice University researchers unveil new model that could sharpen MRI scans

MRI innovation

Researchers at Rice University, in collaboration with Oak Ridge National Laboratory, have developed a new model that could lead to sharper imaging and safer diagnostics using magnetic resonance imaging, or MRI.

In a study recently published in The Journal of Chemical Physics, the team of researchers showed how they used the Fokker-Planck equation to better understand how water molecules respond to contrast agents in a process known as “relaxation.” Previous models only approximated how water molecules relaxed around contrasting agents. However, through this new model, known as the NMR eigenmodes framework, the research team has uncovered the “full physical equations” to explain the process.

“The concept is similar to how a musical chord consists of many notes,” Thiago Pinheiro, the study’s first author, a Rice doctoral graduate in chemical and biomolecular engineering and postdoctoral researcher in the chemical sciences division at Oak Ridge National Laboratory, said in a news release. “Previous models only captured one or two notes, while ours picks up the full harmony.”

According to Rice, the findings could lead to the development and application of new contrast agents for clearer MRIs in medicine and materials science. Beyond MRIs, the NMR relaxation method could also be applied to other areas like battery design and subsurface fluid flow.

“In the present paper, we developed a comprehensive theory to interpret those previous molecular dynamics simulations and experimental findings,” Dilipkumar Asthagiri, a senior computational biomedical scientist in the National Center for Computational Sciences at Oak Ridge National Laboratory, said in the release. ”The theory, however, is general and can be used to understand NMR relaxation in liquids broadly.”

The team has also made its code available as open source to encourage its adoption and further development by the broader scientific community.

“By better modeling the physics of nuclear magnetic resonance relaxation in liquids, we gain a tool that doesn’t just predict but also explains the phenomenon,” Walter Chapman, a professor of chemical and biomolecular engineering at Rice, added in the release. “That is crucial when lives and technologies depend on accurate scientific understanding.”

The study was backed by The Ken Kennedy Institute, Rice Creative Ventures Fund, Robert A. Welch Foundation and Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory.

Luxury transportation startup connects Houston with Austin and San Antonio

On The Road Again

Houston business and leisure travelers have a luxe new way to hop between Texas cities. Transportation startup Shutto has launched luxury van service connecting San Antonio, Austin, and Houston, offering travelers a comfortable alternative to flying or long-haul rideshare.

Bookings are now available Monday through Saturday with departure times in the morning and evening. One-way fares range from $47-$87, putting Shutto in a similar lane to Dallas-based Vonlane, which also offers routes from Houston to Austin and San Antonio.

Shutto enters the market at a time when highway congestion is a hotter topic than ever. With high-speed rail still years in the future, its model aims to provide fast, predictable service at commuter prices.

The startup touts an on-time departure guarantee and a relaxed, intimate ride. Only 12 passengers fit inside each Mercedes Sprinter van, equipped with Wi-Fi and leather seating. And each route includes a pit stop at roadside favorite Buc-ee's.

In announcing the launch, founder and CEO Alberto Salcedo called the company a new category in Texas mobility.

“We are bringing true disruptive mobility to Texas: faster and more convenient than flying (no security lines, no delays), more comfortable and exclusive than the bus or train, and up to 70 percent cheaper than private transfers or Uber Black,” Salcedo said in a release.

“Whether you’re commuting for business, visiting family, exploring Texas wineries, or doing a taco tour in San Antonio, Shutto makes traveling between these cities as easy and affordable as riding inside the city."

Beyond the scheduled routes, Shutto offers private, customizable trips anywhere in the country, a service it expects will appeal to corporate retreat planners, party planners, and tourists alike.

In Houston, the service picks up and drops off near the Galleria at the Foam Coffee & Kitchen parking lot, 5819 Richmond Ave.. In San Antonio, it is located at La Panadería Bakery’s parking lot at 8305 Broadway. In Austin, the location is the Pershing East Café parking lot at 2501 E. Fifth St.

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This article originally appeared on CultureMap.com.

Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”