Rice University and the University of Houston share the accolades of recent entrepreneurship program rankings. Photo via Rice.edu

Rice University and the University of Houston have once again scooped up accolades for their entrepreneurship programs.

For the fifth consecutive year, Rice’s Jones Graduate School of Business has been ranked the No. 1 graduate entrepreneurship program by The Princeton Review, a provider of education services, and Entrepreneur magazine.

“Our close ties to Houston as well as national startup ecosystems give our students unique opportunities to pitch to and connect with angel investors, venture capitalists and corporations,” Brad Burke, managing director of the Rice Alliance, says in a news release. “These connections allow for mentorship, as well as launch points for new ideas, not only for our students but also for the city and surrounding communities.”

The list identifies 50 undergraduate and 50 graduate programs that boast the best entrepreneurship offerings based on factors such as coursework, experiential learning opportunities, and career outcomes. The ranking measures more than 40 data points about the schools’ entrepreneurship programs, faculties, students, and alumni.

Also for the fifth consecutive year, the University of Houston’s Cyvia and Melvyn Wolff Center for Entrepreneurship in the C.T. Bauer College of Business has been named the No. 1 undergraduate entrepreneurship program by The Princeton Review and Entrepreneur magazine.

“We believe in entrepreneurship, we believe in free enterprise, and we’re in the number one city for entrepreneurship,” Dave Cook, executive director of the Wolff Center, says in a news release.

“When we put students into this entrepreneurial mix,” he adds, “and we introduce and reinforce free enterprise values, our intent is to change students’ lives and to create the next generation of business leaders with the highest integrity who are going to go out and create their own cultures, their own companies and their own futures.”

The University of Texas at Austin is the only other school in the state to make the top 10 of either the graduate ranking or undergraduate ranking. UT captures the No. 6 spot on the graduate list and No. 2 spot on the undergraduate list.

Aside from The Princeton Review and Entrepreneur honor, Rice climbed four spots in Poets&Quants’ annual ranking of the world’s best MBA programs for entrepreneurship.

Last year, Rice’s graduate school for business landed at No. 7 on the list. This year, it rose to No. 3, behind the first-ranked Olin School of Business at Washington University in St. Louis and second-ranked ESTM Berlin.

This is the fifth annual ranking of MBA programs for entrepreneurship from Poets&Quants, a website that focuses on graduate-level business education.

“MBA programs are increasingly sought after in today’s environment, and our focus on entrepreneurship sets us apart,” Peter Rodriguez, business dean at Rice, says in a news release. “The entrepreneurship classes emphasize a combination of mindset and skill set and focus on multiple stages of the entrepreneurial process, preparing our students for any industry and climate.”

Poets&Quants relies on 16 data points collected through an annual survey to come up with its ranking. Among those data points are:

  • Average percentage of MBA students launching businesses during their program or within three months of graduation between 2018 and 2022.
  • Percentage of MBA elective courses with all of the curriculum focused on entrepreneurship or innovation during the 2022-23 academic year.
  • Percentage of MBA students active in the business school’s main student-run entrepreneurship club during the 2022-23 academic year.
  • Square footage of incubator or accelerator space available to MBA students during the 2022-23 academic year.
Known as the Wayne B. Duddlesten Free Enterprise Institute, the new program will operate in association with the UH Bauer College’s Cyvia and Melvyn Wolff Center for Entrepreneurship and be open to all UH students. Photo via bauerticker.uh.edu

$5M grant expands entrepreneurship opportunities at UH

coming soon

A $5 million gift from the Wayne Duddlesten Foundation will establish expanded opportunities for entrepreneurship at the University of Houston, according to an announcement from the college earlier this month.

Known as the Wayne B. Duddlesten Free Enterprise Institute, the new program will operate in association with the UH Bauer College’s Cyvia and Melvyn Wolff Center for Entrepreneurship and be open to all UH students. It's expected to launch in 2024.

UH staff from the Duddlesten Institute and the Wolff Center will be able match budding entrepreneurs across campus with mentors, offer website-building resources, provide legal services and other tools.

"Our goal is to empower imaginative thinkers from idea to market," Paul A. Pavlou, dean of the Bauer College of Business and Cullen Distinguished Chair Professor, said in a statement. "We will support the process from a concept to incubation and continue offering necessary resources all the way to launching a successful new business.”

Dave Cook, executive director of the Wolff Center, said the new institute will create a new type of "synergy across campus."

"It will help create a fabric of innovation, talent, financial, legal and technical service along with a commitment to long held values of the importance of character and integrity as businesses are created," Cook said. "We are honored to share this vision through this collaboration.”

Duddlesten has been a longtime supporter of the university. The successful real estate developer, who's credited for bringing the Rockets to Houston in the '70s, was a Houston native and UH graduate.

His foundation donated $5 million to establish an endowed scholarship at Bauer for students studying entrepreneurship or real estate in 2020. It also established an endowed Tier One Scholarship and endowed scholarship in the Graduate College of Social Work, as well as 25 one-time scholarships for Wolff Center students over the years.

Duddlesten also served as a trustee emeritus and advisory board member for the UH Foundation and the UH System Development Board before his death in 2010.


Earlier this academic year, Rice University also unveiled a new facility dedicated to Ralph O'Connor, former president and CEO of the Highland Oil Company and founder of Ralph S. O’Connor & Associates. The $152 million, state-of-the-art facility features five floors of labs, classrooms and seminar rooms, and is Rice's largest core campus research facility. Click here to read more.
UH's business school just received its second largest gift ever. Photo courtesy of University of Houston

University of Houston receives historic $13M gift for its entrepreneurship program

Money moves

University of Houston's C.T. Bauer College of Business has received its second largest donation to benefit its entrepreneurship program.

The Cyvia and Melvyn Wolff Center for Entrepreneurship, which was recently ranked the top undergraduate entrepreneurship program in the country, received the $13 million gift from its namesake foundation — The Cyvia and Melvyn Wolff Family Foundation — and the state of Texas is expected to match an additional $2 million, bringing the total impact to $15 million.

"Our family is deeply committed to the ideals of entrepreneurship," says Cyvia Wolff in a news release. "Our business personified everything that it means to be an entrepreneur. The skills, the thinking, the mindset are fundamental to success for business leaders today and in the future. On behalf of my late husband, we are truly honored to ensure the entrepreneurial legacy not only endures but remains accessible for students. We are truly honored to be part of this program and university."

The money will be used to create three endowments for the program. The Dave Cook Leadership Endowment, named for the center's director, Dave Cook, will be created and funded with $7 million of the donation to support leadership within the organization. For $4 million, the center will create the Wolff Legacy Endowment, which aims to increase students involved in the center, as well as the companies coming out of the program. The last $2 million will be used to create the Cyvia and Melvyn Wolff Endowed Chair(s)/Professorship(s) in Entrepreneurship. This initiative will support research and community outreach.

"We are passionate about entrepreneurship and how it can forever change students' lives," says Bauer Dean Paul A. Pavlou in the release. "We seek to further promote entrepreneurship as a university-wide, even citywide effort, by collaborating within and across the university in a multitude of areas, such as technology, health care, arts and sports."

The program was created in the mid '90s and was later renamed after Cyvia and Melvyn Wolff in 2007, and has seen great success over the past decade. In that time, Wolff students have created 1,270 businesses, with identified funding of just over $268 million. According to the release, the program has been ranked in the top two spots of the Princeton Review's top undergraduate entrepreneurship programs for nine of the past 12 years.

"Entrepreneurship is crucial for the future of our country, as well as our city and state," says UH President Renu Khator in the release. "We are proud to be at the forefront of work around entrepreneurial training and research. The uniqueness of our program has and continues to make it the model program. This extraordinary gift ensures our leadership in this space will continue and will support the creation of businesses, change communities and impact our students' lives."

At UH, 2,500 students take at least one entrepreneurship course a year, and more than 700 students complete certificate programs.

"What we are doing is transformative in the lives of students, mentors and stakeholders in a way that elevates everyone towards excellence," Cook, who was named the director of the program in 2017, says in the release. "The impact of this gift allows us to remain the leader and to move forward with confidence, purpose and permanence."

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."