Cadence is investing in Girlstart, an Texas-based nonprofit empowering women in STEM. Photo by Amber Heckler

This week, the worlds of the Lone Star State's tech scene, women in STEM, and Formula 1 collided.

At a private event on Wednesday, October 19, hosted by computational software company Cadence Design Systems, Senior VP of Global HR Tina Jones spoke highly about the pride she felt about Cadence’s company culture and their goals for leaving the world better than they found it in regards to sustainability and giving back to the community. Last week, Cadence was ranked 19th in the 2022 World’s Best Workplaces list.

One of the ways Cadence is giving back to the community is through their Giving Foundation. The foundation is investing in organizations like Girlstart, an Austin-based nonprofit whose mission is to empower young girls’ interest in STEM through educational programs and camps.

“We are determined to make a difference in access to STEM education for those who have been traditionally underrepresented,” Jones said.

Jones announced Cadence would make a $25,000 donation to Girlstart to help further the organization’s mission and to invest in the future women they want to hire. The organization has locations all around Texas, including Dallas, Houston, San Antonio and the Rio Grande Valley, as well as locations in other states like California, Illinois, Washington, and Massachusetts.

“We want to start at Kindergarten and take them through 12th grade and give girls confidence in STEM,” Jones said, “Girlstart is doing that here in Austin, and we’re super proud to be associated with them.”

Girlstart Executive Director Shane Woods was present to accept the donation. During her speech, Woods discussed the importance of broadening young women’s understanding of what STEM is and nurturing a positive mentality so they can stay inspired in their careers.

Part of Woods’ work is to make sure girls know about the different fields that “need STEM eyes” such as biomedical engineering, environmental sustainability, and social justice.

The rest of the event centered around Cadence’s partnership with F1 team McLaren Racing, with three primary team members in attendance – CEO Zak Brown, Team Principal Andreas Seidl, and driver Daniel Ricciardo.

Ricciardo has never been shy about his love for the capital of Texas. He said he was naive about the city when F1 first arrived in 2012, but now it’s one of his favorite places. Circuit of the Americas is one of his favorite challenging tracks, noting the “high speed snake section” at turns three through eight that remind him of similar turns Maggotts and Becketts at Silverstone.

“A circuit that really pushes the car to the limits is fun,” he said, “That’s what I love about Austin.”

McLaren’s partnership with Cadence is significant for more than their expertise with computational fluid dynamics. Both companies share similar goals in regards to environmental sustainability and equality. In 2021, McLaren became the first F1 team to release an annual sustainability report, showing they are on track to achieve carbon net zero by 2040. In that same year, they announced Emma Gilmour would be the team’s first female racing driver, racing in Extreme E alongside Tanner Foust.

When asked about what they predict the next 10 years of Formula 1 will look like, Brown and Ricciardo agreed they hoped to see F1 still thriving and at the pinnacle of motorsport, while also giving recognition to the rise of other motorsports. Brown said he would like to see the introduction of rotational races in other countries.

“We have a lot of countries that want races. We’re at a maximum schedule of 24…I would love to see us in 30 countries, but 24 times a year. You might land on 18 permanent races and then have 10 that rotate every two years or something like that,” Brown said. “I think there’s room to grow the sport globally."

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This article originally ran on CultureMap.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.