Houston's health tech and startup ecosystem has some recent news to catch up on. Photo via Getty Images

Houston startup founders have been moving and shaking in the local innovation ecosystem — from growing their executive boards to raising fresh grant funding.

In this roundup of Houston startup and innovation news, a startup opens a crowdfunding round, a Houston hospital system taps into new technology, and more.

Coya Therapeutics names new president and chief medical officer

Fred Grossman will assume his new role next week. Photo via LinkedIn

Coya Therapeutics Inc. (NASDAQ: COYA), a revolutionary biotech company based in Houston, named Dr. Fred Grossman as president and chief medical officer. The clinical-stage company, which has developed a biologics therapy that prevents further spreading of neurodegenerative diseases by making regulatory T cells functional again, announced the closing of its $15.25 million IPO in January.

According to the company, Dr. Grossman's position, which was held by Dr. Adrian Hepner, is effective July 17.

“We are grateful for Dr. Hepner’s leadership and excellence in positioning Coya and look forward to having him continue to collaborate with the company in moving our assets forward," Howard H. Berman, CEO of Coya, says in a news release. "We also welcome Dr. Grossman, who brings decades of clinical development experience and successful execution."

Dr. Grossman has held executive positions at Eli Lilly, Johnson & Johnson, Bristol Myers Squibb, Sunovion, Glenmark Pharmaceuticals, and Mesoblast Inc. (NASDAQ: MESO), developing allogeneic cellular therapies for inflammatory diseases.

CellChorus receives another SBIR grant

CellChorus, a biotech startup operating out of the University of Houston Technology Bridge, has secured additional funding. Photo via Getty Images

Fresh off a $2.3 million grant last month, Houston-based CellChorus, a single-cell analysis company, has another grant to celebrate.

The U.S. National Science Foundation has awarded CellChorus a Small Business Innovation Research (SBIR) grant to advance development of its Time-lapse Imaging Microscopy In Nanowell Grids, known as TIMING. The funding will be used to develop novel microscale arrays to support scaling dynamic single-cell analysis.

“This funding will further development of novel arrays to build on the success of our early access laboratory based in Houston,” says Mohsen Fathi, head of technology at CellChorus, in a press release. “This project will support scaling the only platform that can evaluate migration, contact dynamics, killing, survival, subcellular activity, and biomolecule secretion for the same individual cell over time and in high throughput to improve development and delivery of novel therapies.”

According to the release, the company is receiving more than $274,000 as a part of the grant, but CellChorus has the potential of receiving up to $2 million from the second phase.

“This award builds on our recent funding from the National Institute of General Medical Sciences to advance development of a dedicated instrument platform for TIMING,” says Daniel Meyer, CEO of CellChorus, in the release.

Memorial Hermann partners with TMC-backed virtual OB-GYN care

Two Houston-area hospitals now have access to this digital health startup's platform. Photo via Getty Images

The Memorial Hermann Health System has entered into a partnership with Washington, D.C.-based Babyscripts, a virtual care platform for managing obstetrics. The company is backed by the Texas Medical Center's venture fund and has existing ties to the city.

"Memorial Hermann strives to make Greater Houston a place where every woman's pregnancy, delivery and postpartum experience is successful and safe. This innovative partnership is a continuation of that commitment," says Dr. Victoria Regan, vice president of Women's and Children's Services at Memorial Hermann, in a news release.

Now, Memorial Hermann patients will be able to access Babyscripts myJourney, an app that delivers educational content, email campaigns, satisfaction surveys, appointment reminders, and more. The first two hospitals to receive access are Memorial Hermann Memorial City Medical Center and Memorial Hermann The Woodlands Medical Center, with plans to expand the program.

"The ability to access adequate prenatal and postpartum care is one of the largest predictors of maternal and infant health outcomes," says Anish Sebastian, CEO and co-founder of Babyscripts in the release. "With Babyscripts, Memorial Hermann is able to streamline the maternal health experience across their system, adding opportunities for access and providing consistent, high-quality pregnancy care to all patients, regardless of race, income, geography or risk."

Earn Your Freedom launches crowdfunding campaign with Houston nonprofit's support

Earn Your Freedom is looking for financial support from its community. Photo via houston.impacthub.net

Earn Your Freedom, a Houston startup that's gamifying personal finance education, has launched its first crowdfunding campaign in partnership with Impact Hub Houston.

The goal for EYF is to raise $100,000 to support its gaming programs with local schools. Impact Hub Houston is the fiscal sponsor for the raise, which is officially live and open for contributions.

The innovative and interactive web and mobile video game, which officially launched earlier this year to celebrate Financial Literacy Month, was designed to help kids build a strong foundation in money management, economics and investment in a fun and engaging way. It features challenges and real-world scenarios such as renting a first apartment, opening a first bank account, budgeting at the grocery store, buying stocks and index funds and renting or buying real estate.

“We envision a society where financial literacy is accessible to all, and where individuals are enabled with the tools to take control of their financial futures," says Keely McEnery, EYF co-founder and COO, in a press release. "We are bridging the gap between education and application, stepping in before the real-world consequences take place.”

CellChorus, a biotech startup operating out of the University of Houston Technology Bridge, has secured fresh funding. Photo via Getty Images

Houston biotech startup secures $2.3M grant

cha-ching

They say it’s all in the timing. For CellChorus, it’s all in the TIMING. That’s Time-lapse Imaging Microscopy In Nanowell Grids. TIMING is a visual AI program that evaluates cell activation, killing and movement, which allows scientists to better understand how cells function.

The technology is important to the development of novel therapies in the realms of oncology, infectious diseases, and countless other disorders and diseases. By allowing scientists to observe those maladies at their roots, it will enable them to create, and ultimately deliver new medications and other therapies faster, at lower cost, and with a higher success rate.

CellChorus is a spinoff of the Single Cell Lab at the University of Houston. Part of UH’s Technology Bridge, CEO Daniel Meyer connected with co-founder and leader of Single Cell Lab, Navin Varadarajan, through co-founder Laurence Cooper.

“The company had been established, but there were limited operations,” recalls Meyer during a phone call with InnovationMap.

That was the fall of 2020. Now, the team has just announced a $2.3 million SBIR (Small Business Innovation Research) Fast-Track grant from the National Institute of General Medical Sciences.

“This funding will support development of a product offering that builds on the success of our early access laboratory,” Cooper said in a press release. “As the next frontier of cellular analysis, dynamic single-cell analysis will increase the impact that immunotherapies have in improving the lives of patients.”

Meyer is based in the Bay Area, but the rest of the team is in Houston. Meyer has a proven track record as an investor and early stage entrepreneur in life sciences companies, including work as COO of Genospace, which was acquired by HCA Healthcare.

Meyer says that what attracted him to CellChorus was a combination of a clear need for the technology and the fact that it was “very well validated.“

“Developers of immunotherapies need better functional data earlier so that they can develop and deliver better therapies,” he explains.

Another aspect of its appeal was the fact that more than 10 publications featured data from the TIMING platform.

“We’ve had both large and small biopharmas publish data,” says Meyer. “That’s important as well because it shows there’s applicability in both nonprofit and for-profit research.”

Though Meyer himself doesn’t currently live in Houston, he recognizes its importance to CellChorus. He says that it can be difficult for an early stage company to find appropriate lab space, so Technology Bridge was of exceptional importance for CellChorus. Since opening the lab a year and a half ago, Varadarajan and his team have been busy.

“Example projects we have completed include understanding mechanism of action for cell therapy products, selecting lead candidates for T cell engagers, identifying biomarkers of response to cell therapies, and quantifying potency and viability for cell therapy manufacturing technologies,” says Meyer.

And now, CellChorus is collaborating with leaders in the industry.

“These include top-25 biopharmaceutical companies and promising venture-backed biotechnology companies, as well as leading not-for-profit research institutions,” says Meyer in a press release. It’s clear that the TIMING is right for CellChorus to excel.

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CultureMap Emails are Awesome

Innovation and new business incubation at the University of Houston’s Technology Bridge is on a roll

Start Me Up

When Jacob Thomas first came to the University of Houston’s Technology Bridge in 2016, he knew it was the perfect incubator space to grow his company, Alchemy Sciences. The excellent support infrastructure enabled the fledgling oil recovery business to focus on improving its technology, product and business development, and operations.

“Technology Bridge also had the advantage of being located at a premier, research-focused university that afforded the opportunity to collaborate not just with other startups but with groundbreaking innovators on campus,” Thomas says.

And when Hadi Ghasemi, an associate professor in the UH Cullen College of Engineering, launched Elemental Coatings for his revolutionary anti-icing material in 2019, his ideal space was literally minutes from his campus laboratory.

“We have one of the best spaces in town right here near campus,” he says. “From a ready-made workforce to the facilities, it was a unique opportunity that was perfect for us.”

Thomas and Ghasemi aren’t alone in their assessments. They are part of a booming community of entrepreneurs setting up shop in Technology Bridge, Houston’s premier innovation park for technology commercialization, industrial partnerships, and startup development, located adjacent to the UH campus along the Gulf Freeway.

Connecting people and ideas

UH prides itself on spurring innovation, from the first spark of an idea to the transfer of knowledge and technology. The University is home to the nation’s top-ranked undergraduate entrepreneurship program and is one of the top 25 royalty-earning universities in the United States. And for seven of the past eight years, UH has ranked among the top 100 global universities for the number of utility patents issued.

Tanu Chatterji, the associate director of startup development at Technology Bridge, includes those accolades in her pitch to prospective tenants. But it’s the wealth of established relationships with UH researchers and potential employees already on campus that is the biggest selling point.

“If you are looking to grow a company and plug into a major ecosystem, Technology Bridge is where you want to be. You have access to the talent, expertise, facilities, and resources you need to be successful,” says Chatterji, noting that UH is a Carnegie-designated Tier One research university with 35 faculty members in the National Academy of Inventors.

"The students, faculty and resources at the heart of our ecosystem set us apart from everyone else," says Ramanan Krishnamoorti, UH vice president of energy and innovation.

Right now, Technology Bridge has more than 20 companies utilizing a wealth of amenities, including private and shared incubator lab spaces designed to support chemical, mechanical, and life sciences startups.

The Innovation Center features large, fully equipped and furnished office spaces with open and private areas, conference rooms and collaborative meeting areas, and a common kitchen area.

Additionally, startups receive unmatched access to UH faculty, one-on-one mentorship opportunities, and the full support of the UH Office of Technology Transfer and Innovation to help with funding, workshops, grant development, and commercialization.

“This is an innovation environment that is unique to Houston. We’re all about connecting people and ideas,” Chatterji says.

A community for innovators

To access the benefits of Technology Bridge and enjoy its competitive rental rates, companies are required to fulfill certain criteria. This includes committing to a minimum one-year contract and actively engaging with the UH innovation community at one of three levels: hiring university talent, working collaboratively on projects with faculty or sponsoring research, or commercializing UH intellectual property.

“We’re not looking to give out cheap space to anyone who’s just going to move out in three years,” Chatterji says. “We really want the right partners on board to help us cultivate this ecosystem.”

Technology Bridge is home to a diverse mix of companies, comprising both external organizations and spinoffs founded by faculty, graduate students, and staff. While some ventures are still in the early stages, actively seeking funding and assembling their teams, a handful have already reached the exciting milestone of selling products and are preparing to transition into larger, more permanent facilities.

“The higher the engagement, the higher the discount they get on their lease,” Chatterji says. “On the flip side, there’s incentive for UH to keep these companies within our family so we get to share new ideas and innovations and they can mentor our faculty and students.”

Building for the future

It’s not only innovators who are taking notice of the remarkable developments happening at Technology Bridge.

U.S. Rep. Sylvia Garcia, who represents Texas’29th congressional district where Technology Bridge is located, helped secure nearly $3 million in federal funding for infrastructure improvements that will further grow its position as a leader in Houston’s innovation space.

“We have a lot of momentum at Technology Bridge as we continue to support Houston’s growing innovation economy,” says Ramanan Krishnamoorti, vice president of energy and innovation at UH. “We’re building great partnerships and providing these startups with everything they need to commercialize technologies and be successful.”

Most of the $2.875 million will benefit the UH Industry & International Innovation Hub (UHI), a planned center for industry partner engagement with an investor and mentoring studio and event space.

It will also increase onsite industry and startup capacity and establish workforce development and training rooms. The remaining money will be used to establish The Deck Innovation & Coworking Center, with eight new private offices that will increase lease revenue by a projected 150 percent. The entire project is expected to increase capacity by more than 20 companies.

“No other space in Houston has what we have,” adds Krishnamoorti. “It’s not just the Tech Bridge, it’s the University of Houston Tech Bridge. The students, faculty, and resources at the heart of our ecosystem set us apart from everyone else.”

Success stories

In recent years, startups at Technology Bridge have developed innovations in advanced materials, pharmaceuticals, and food and agriculture, as well as infrastructure and construction, optometry, medical devices, and computer software.

Among their accomplishments are hundreds of groundbreaking inventions such as a plant-based polymer with the potential to replace petroleum-based plastics and revolutionary therapeutics that have had a profound impact on patients worldwide, offering treatments for cancer, Alzheimer’s disease, and epilepsy.

Thomas’ Alchemy Sciences, renowned for its portfolio of products that enhance the efficiency of oil and gas production in multiple basins across the United States, is now embarking on the early stages of expansion to Latin America. The company recently graduated from Technology Bridge, moving into a larger space to accommodate its growing operations.

“An incubation ecosystem like this is essential for technology startups as they begin their journey” Thomas says. “The proactive staff, modern lab facilities, and associated support system enabled us to conduct experimental work efficiently and was key to our growth over the past five years.”

Elemental Coatings, a company founded on technology pioneered by Ghasemi at his UH lab, produces anti-icing surfaces with exceptional durability, even in the harshest environmental conditions. After four years at Technology Bridge, Ghasemi said the company will double its workforce and move into a bigger facility early next year.

“When we started this journey, there were maybe two companies at Technology Bridge, so it’s been amazing to see this growth,” says Ghasemi. “Access to a knowledgeable workforce, along with the facilities and support for intellectual property protections and patents, was essential for us and is crucial for any startup.”

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from software to biotech — recently making headlines in Houston innovation.


Gaurab Chakrabarti, CEO and co-founder of Solugen

Solugen has announced two major partnerships. Photo via solugentech.com

Solugen had a busy week. The Houston-based company that makes sustainable chemicals announced two new partnerships.

Solugen and Sasol Chemicals, a business unit of Saslo Ltd., revealed that they are working together to explore commercialization of sustainably-made home and personal care products. Read more.

Later last week, Solugen announced that it has scored a partnership with ADM to build a biomanufacturing facility adjacent to an existing corn complex in Marshall, Minnesota. Read more.

Andy Grolnick, CEO of Graylog

Graylog, a Houston SaaS company, has new fuel to scale and develop its product. Photo via Graylog

A Houston software-as-a-service company has secured $39 million in financing and announced its latest upgrade to its platform.

Graylog, which has created an innovative platform for cybersecurity and IT operations, raised equity funding with participation from new investor Silver Lake Waterman and existing investors Piper Sandler Merchant Banking and Harbert Growth Partners leading the round.

“The growth we are seeing globally is a response to our team’s focus on innovation, a superior user experience, low total cost of ownership, and strong execution from our Go-To-Market and Customer Success teams,” Andy Grolnick, CEO of Graylog, says in a news release. “We expect this momentum to continue as Graylog expands its reach and raises its profile in the security market.” Read more.

Stuart Corr, executive director of Pumps & Pipes

A Houston expert shares reasons to swap screen time for extended reality. Photo via pumpsandpipes.org

Virtual and augmented reality are having a moment, as Stuart Corr, executive director of Pumps & Pipes, explains in a guest column for InnovationMap.

"The COVID-19 pandemic saw an unprecedented shift to even more screen time and interactions using remote video communication platforms," he writes. "It was also around this time that wireless virtual reality headsets were, for the first time ever, economically accessible to the consumer due to the large push of one multinational corporation. Fast forward to 2023, there are even more companies beginning to enter the market with new extended reality (XR) headsets (i.e. virtual, mixed, and augmented reality) that offer spatial computing – the ability for computers to blend into the physical worlds (amongst other things)."Read more.

Houston space tech company snags $9.5M contract, sets launch date for lunar mission

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Business at Houston-based space exploration company Intuitive Machines is taking off on two fronts.

First, Intuitive Machines has landed a nearly $9.5 million Air Force contract to develop technology for NASA’s Gateway project, the first space station that will orbit the moon. Specifically, the technology will support a high-powered nuclear fission system that will supply electricity for satellites, bypassing the need for power from solar, battery, or fuel-cell sources.

“As space exploration ventures become more ambitious and diverse, the need for efficient and reliable power sources in space is paramount,” Pete McGrath, vice president of business development at Intuitive Machines, says in a news release. “Developing the ability to expand power sources beyond solar, which requires heavy battery storage, could remove the burden of constantly worrying about a spacecraft’s arrays relative to the sun, and potentially deliver long-term stability for satellites that would otherwise lose power over time.”

Second, Intuitive Machines has set January window for the launch of its IM-1 lunar mission in conjunction with private aerospace company SpaceX. The liftoff is targeted for a multiday window that opens January 12, 2024.

“There are inherent challenges of lunar missions; schedule changes and mission adjustments are a natural consequence of pioneering lunar exploration,” Steve Altemus, co-founder, president, and CEO of Intuitive Machines, says in a news release. “Receiving a launch window and the required approvals to fly is a remarkable achievement, and the schedule adjustment is a small price to pay for making history.”

The IM-1 mission will be the company’s first attempted lunar landing as part of NASA’s commercial payload initiative.

Intuitive Machines went public earlier this year via SPAC. Co-founder Tim Crain shared a bit of the origin story of the company on a recent episode of the Houston Innovators Podcast.