3 Houston innovators to know this week

hou to know

This week's roundup of Houston innovators includes Brianna Brazle of CultureLancer, Sameer Soleja of Molecule, and Emerson Perin of Texas Heart Institute. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health care to energy tech — recently making headlines in Houston innovation.

Brianna Brazle, founder of CultureLancer

Houston founder joins DivInc's newest accelerator that supports Web3 companies with a social impact. Photo courtesy

DivInc, aTexas-based accelerator focused on helping BIPOC and female founders on their entrepreneurial journeys, announced the inaugural class for its newest accelerator. DWeb for Social Impact Accelerator, a 12-week intensive hybrid program sponsored by Filecoin Foundation for the Decentralized Web, will mentor nine companies, all of whom integrate Web3 technologies into their impact entrepreneurship.

One Houston-based startup, CultureLancer, will be participating in the program. Founded by Brianna Brazle, the career-focused platform matches students from HBCU with companies looking to hire in the fields of business development, data analysis, marketing, and operations.

“That’s a problem that has been existing and then after doing more research I learned historically about 56%, year over year, of college graduates find themselves unemployed or underemployed,” Brazle explains. “My first solution to this problem was a hybrid marketplace.” Read more.

Sameer Soleja, founder and CEO of Molecule

Sameer Soleja has expanded his company's platform. Photo courtesy of Molecule Software

Houston startup Molecule Software hopes to get a big bang out of its new platform for the energy and commodities markets. The data-as-a-lake platform, Bigbang, is available as an add-on for current Molecule customers. It enables energy trading and risk management (ETRM) and commodities trading and risk management customers to automatically import trade data from Molecule, and then merge it with various sources to conduct queries and analysis.

Molecule sells Bigbang at a monthly rate through either a yearly or multiyear contract.

“We’re seeing a growing need in the energy and commodities trading space for a turnkey data lake, as indicated by our own customers. They need real-time and automated data streaming from key systems, the ability to query the data quickly and easily, and access to the data using the analytics tools they know well,” says Sameer Soleja, founder and CEO of Molecule. Read more.

Emerson Perin, medical director of The Texas Heart Institute

Emerson Perin of the Texas Heart Institute, recently published the largest clinical trial of cell therapy for patients with chronic heart failure to-date included 580 patients at 52 sites throughout North America. Photo via texasheart.org

Emerson Perin’s end goal isn’t to treat heart failure. The medical director of The Texas Heart Institute says that he has his sights set firmly on curing the malady altogether. And, with the power of innovation and a strong team, the Houston-based cardiologist has a good chance of meeting his objective.

Perin first came to THI for fellowship training in 1988, following his residency in Miami and medical school in his birthplace of Brazil.

“This is a very special place,” the physician and researcher, whose titles also include director for THI’s Center for Clinical Research and vice president for medical affairs, tells InnovationMap. “It has a worldwide-reaching reputation. I’ve always liked research and this is a great place in terms of innovation and practicing high-level cardiology.” Read more.

DivInc's newest accelerator based in Houston will support Web3 companies with a social impact. Photos courtesy of DivInc

Texas organization announces inaugural cohort of social enterprise startups with Web3 tech

Dedicated to DWeb

A Texas-based accelerator focused on helping BIPOC and female founders on their entrepreneurial journeys announced the inaugural class for its newest accelerator.

DivInc's DWeb for Social Impact Accelerator, a 12-week intensive hybrid program sponsored by Filecoin Foundation for the Decentralized Web, will mentor nine companies, all of whom integrate Web3 technologies into their impact entrepreneurship. Participating startups will have access to the Ion’s resources and receive a non-dilutive $10,000 grant to use during the course of the program.

Cherise Luter, marketing director at DivInc, says the Austin-based development program instead chose Houston to host this inaugural cohort because they have a secure partnership with the Ion and other premiere partners in the area, including Mercury, JP Morgan, and Bank of America.

“The team that we already have in place in Houston is so strong, we thought, this would be a great place to launch this concept and then from there determine if we want to launch it in Austin,” Luter says.

Amanda Moya, director of programs for DivInc, says this accelerator will truly be hybrid, enabling entrepreneurs from around the country to benefit from quality virtual mentorship and four weeks of in-person training.

“We want to really engulf them in the Houston innovation ecosystem, to let them know that this is also a landing pad if they are ever to move or travel around and come back to Houston,” Moya mentions.

One Houston-based startup, CultureLancer, will be participating in the program. A career-focused platform that matches students from HBCU with companies looking to hire in the fields of business development, data analysis, marketing, and operations, CultureLancer provides students with project-based learning opportunities.

Brianna Brazle, CultureLancer founder and therapist, says after discussing with friends and family members their struggles to get hired post-graduation she uncovered an underserved market of people in need of career guidance.

“That’s a problem that has been existing and then after doing more research I learned historically about 56%, year over year, of college graduates find themselves unemployed or underemployed,” Brazle explains. “My first solution to this problem was a hybrid marketplace.”

The rest of the inaugural cohort includes one to two entrepreneurs from the following companies:

  • Craftmerce, based in Dallas, is a B2B technology platform that brings African artisans and mainstream retail partners together through distributed production, enterprise management, and financing tools.
  • Instarails is working to simplify cross border payments through their API which provides the option to make instant global payments regardless of currency.
  • Looks for Lease, a Los Angeles based wardrobe rental company is combating the carbon emissions brought on by the fashion industry through their circular consumerism business model which operates on an AR platform.
  • Motherocity is an app that allows postpartum moms to track their mental and physical health through personal insights, experiential data, data science, and artificial intelligence, all the way through the first year after giving birth.
  • Salubata combines sustainable fashion and tech through their shoes made from old plastic bottles and integrating an NFT component that allows access to new shoe designs for customers.
  • Seed At The Table is a crowdfunding platform connecting marginalized founders with non-accredited investors, founded by a former Goldman Sachs investment manager.
  • Tribe is a mental health mobile app aiming to make mental healthcare affordable and accessible to black people through their directory of black therapists whose patients can directly book appointments within the app.
  • Subler, which was founded by a Los Angeles high school board member, is a digital marketplace that allows schools to rent out their unused spaces to local community groups.

The program will run from Sept. 18 until their demonstration day which is scheduled for Dec. 7 at the Ion.

DivInc, which runs several accelerators across Texas, originally partnered with the Ion in 2020. The organization introduced its new DWeb program earlier this year.

Last month, DivInc also introduced its inaugural cohort to another new diversity-focused accelerator. The 2023 Clean Energy Tech accelerator program sponsored by Chevron and Microsoft is currently ongoing.

The latest Houston cohort for gBETA has been announced. Photo courtesy of gBETA

Early-stage startup accelerator names latest Houston cohort

ready to grow

The sixth Houston cohort for global startup accelerator and investor gener8tor's gBETA program is underway, and five Houston early-stage companies have joined the program.

The no-equity program, which is based out of the Downtown Launchpad, kicked off in September and lasts seven weeks. In that time, the startups are connected to a national network of mentors, customers, corporate partners, and investors.

“This gener8tor Houston cohort is among our strongest yet,” says Robert Pieroni, director of Economic Development at Central Houston Inc., in the news release. “We are excited about the caliber of entrepreneurs the Downtown Launchpad is attracting and the entrepreneurial ecosystem being created.”

The program concludes at a public showcase event at 5 pm on November 17 at Amegy Bank Courtyard.

“I’m thrilled about this cohort,” says Muriel Foster, gBETA Houston director, in the release. “We’ve seen the incredible economic impact of the gBETA program in other parts of the country, and we’re excited to bring that same impact to Houston.”

Here are the members of gBETA Houston's latest cohort:

CultureLancer

CultureLancer's all-in-one career-focused platform connects students at HBCUs with opportunities to gain industry-specific education and experience. CultureLancer also provides companies with the ability to source qualified diverse talent to meet their needs. CultureLancer has onboarded 30 students with each completing certification in digital marketing, closing on two contracts, and currently onboarding companies for beta testing.

EYF

EYF gamifies financial literacy education and provides children with a fun alternative to educational programming. EYF aims to teach financial literacy and economics in a fun, interactive, and applicable way. EYF is set to go to market at the end of of the year.

Oodles

Oodles automates the sales process and 24/7 customer service for e-commerce retailers through a conversational AI chatbot. Leveraging AI and machine learning, Oodles chatbot results in significant cost savings for retailers and improves customer retention and loyalty. Oodles has currently raised a seed round of $280,000, launched the product, and onboarded 10 customers.

SafetyKay

SafetyKay LLC promotes safety awareness to young children. SafetyKay focuses on decreasing fatality and accident rates among children ages 5-12 years by teaching them critical health and safety skills. SafetyKay's current safety awareness material has been viewed 81,359 times and it is currently in the process of transitioning into a mobile app platform.

Stobridge Education Inc.

Stobridge Education Inc. connects students with mentors and postsecondary education college, career and life resources for better outcomes. Through its comprehensive and fully integrated web and mobile platform, Stobridge Education is a safer alternative to LinkedIn for high school students. Stobridge Education has engaged with over 1,000 participants through their nonprofit partner, Adeiur and has implemented its module curriculum in two universities and four student-serving organizations.

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​Planned UT Austin med center, anchored by MD Anderson, gets $100M gift​

med funding

The University of Texas at Austin’s planned multibillion-dollar medical center, which will include a hospital run by Houston’s University of Texas MD Anderson Cancer Center, just received a $100 million boost from a billionaire husband-and-wife duo.

Tench Coxe, a former venture capitalist who’s a major shareholder in chipmaking giant Nvidia, and Simone Coxe, co-founder and former CEO of the Blanc & Otus PR firm, contributed the $100 million—one of the largest gifts in UT history. The Coxes live in Austin.

“Great medical care changes lives,” says Simone Coxe, “and we want more people to have access to it.”

The University of Texas System announced the medical center project in 2023 and cited an estimated price tag of $2.5 billion. UT initially said the medical center would be built on the site of the Frank Erwin Center, a sports and entertainment venue on the UT Austin campus that was demolished in 2024. The 20-acre site, north of downtown and the state Capitol, is near Dell Seton Medical Center, UT Dell Medical School and UT Health Austin.

Now, UT officials are considering a bigger, still-unidentified site near the Domain mixed-use district in North Austin, although they haven’t ruled out the Erwin Center site. The Domain development is near St. David’s North Medical Center.

As originally planned, the medical center would house a cancer center built and operated by MD Anderson and a specialty hospital built and operated by UT Austin. Construction on the two hospitals is scheduled to start this year and be completed in 2030. According to a 2025 bid notice for contractors, each hospital is expected to encompass about 1.5 million square feet, meaning the medical center would span about 3 million square feet.

Features of the MD Anderson hospital will include:

  • Inpatient care
  • Outpatient clinics
  • Surgery suites
  • Radiation, chemotherapy, cell, and proton treatments
  • Diagnostic imaging
  • Clinical drug trials

UT says the new medical center will fuse the university’s academic and research capabilities with the medical and research capabilities of MD Anderson and Dell Medical School.

UT officials say priorities for spending the Coxes’ gift include:

  • Recruiting world-class medical professionals and scientists
  • Supporting construction
  • Investing in technology
  • Expanding community programs that promote healthy living and access to care

Tench says the opportunity to contribute to building an institution from the ground up helped prompt the donation. He and others say that thanks to MD Anderson’s participation, the medical center will bring world-renowned cancer care to the Austin area.

“We have a close friend who had to travel to Houston for care she should have been able to get here at home. … Supporting the vision for the UT medical center is exactly the opportunity Austin needed,” he says.

The rate of patients who leave the Austin area to seek care for serious medical issues runs as high as 25 percent, according to UT.

New Rice Brain Institute partners with TMC to award inaugural grants

brain trust

The recently founded Rice Brain Institute has named the first four projects to receive research awards through the Rice and TMC Neuro Collaboration Seed Grant Program.

The new grant program brings together Rice faculty with clinicians and scientists at The University of Texas Medical Branch, Baylor College of Medicine, UTHealth Houston and The University of Texas MD Anderson Cancer Center. The program will support pilot projects that address neurological disease, mental health and brain injury.

The first round of awards was selected from a competitive pool of 40 proposals, and will support projects that reflect Rice Brain Institute’s research agenda.

“These awards are meant to help teams test bold ideas and build the collaborations needed to sustain long-term research programs in brain health,” Behnaam Aazhang, Rice Brain Institute director and co-director of the Rice Neuroengineering Initiative, said in a news release.

The seed funding has been awarded to the following principal investigators:

  • Kevin McHugh, associate professor of bioengineering and chemistry at Rice, and Peter Kan, professor and chair of neurosurgery at the UTMB. McHugh and Kan are developing an injectable material designed to seal off fragile, abnormal blood vessels that can cause life-threatening bleeding in the brain.
  • Jerzy Szablowski, assistant professor of bioengineering at Rice, and Jochen Meyer, assistant professor of neurology at Baylor. Szablowski and Meyer are leading a nonsurgical, ultrasound approach to deliver gene-based therapies to deep brain regions involved in seizures to control epilepsy without implanted electrodes or invasive procedures.
  • Juliane Sempionatto, assistant professor of electrical and computer engineering at Rice, and Aaron Gusdon, associate professor of neurosurgery at UTHealth Houston. Sempionatto and Gusdon are leading efforts to create a blood test that can identify patients at high risk for delayed brain injury following aneurysm-related hemorrhage, which could lead to earlier intervention and improved outcomes.
  • Christina Tringides, assistant professor of materials science and nanoengineering at Rice, and Sujit Prabhu, professor of neurosurgery at MD Anderson, who are working to reduce the risk of long-term speech and language impairment during brain tumor removal by combining advanced brain recordings, imaging and noninvasive stimulation.

The grants were facilitated by Rice’s Educational and Research Initiatives for Collaborative Health (ENRICH) Office. Rice says that the unique split-funding model of these grants could help structure future collaborations between the university and the TMC.

The Rice Brain Institute launched this fall and aims to use engineering, natural sciences and social sciences to research the brain and reduce the burden of neurodegenerative, neurodevelopmental and mental health disorders. Last month, the university's Shepherd School of Music also launched the Music, Mind and Body Lab, an interdisciplinary hub that brings artists and scientists together to study the "intersection of the arts, neuroscience and the medical humanities." Read more here.

Your data center is either closer than you think or much farther away

houston voices

A new study shows why some facilities cluster in cities for speed and access, while others move to rural regions in search of scale and lower costs. Based on research by Tommy Pan Fang (Rice Business) and Shane Greenstein (Harvard).

Key findings:

  • Third-party colocation centers are physical facilities in close proximity to firms that use them, while cloud providers operate large data centers from a distance and sell access to virtualized computing resources as on‑demand services over the internet.
  • Hospitals and financial firms often require urban third-party centers for low latency and regulatory compliance, while batch processing and many AI workloads can operate more efficiently from lower-cost cloud hubs.
  • For policymakers trying to attract data centers, access to reliable power, water and high-capacity internet matter more than tax incentives.

Recent outages and the surge in AI-driven computing have made data center siting decisions more consequential than ever, especially as energy and water constraints tighten. Communities invest public dollars on the promise of jobs and growth, while firms weigh long-term commitments to land, power and connectivity.

Against that backdrop, a critical question comes into focus: Where do data centers get built — and what actually drives those decisions?

A new study by Tommy Pan Fang (Rice Business) and Shane Greenstein (Harvard Business School) provides the first large-scale statistical analysis of data center location strategies across the United States. It offers policymakers and firms a clearer starting point for understanding how different types of data centers respond to economic and strategic incentives.

Forthcoming in the journal Strategy Science, the study examines two major types of infrastructure: third-party colocation centers that lease server space to multiple firms, and hyperscale cloud centers owned by providers like Amazon, Google and Microsoft.

Two Models, Two Location Strategies

The study draws on pre-pandemic data from 2018 and 2019, a period of relative geographic stability in supply and demand. This window gives researchers a clean baseline before remote work, AI demand and new infrastructure pressures began reshaping internet traffic patterns.

The findings show that data centers follow a bifurcated geography. Third-party centers cluster in dense urban markets, where buyers prioritize proximity to customers despite higher land and operating costs. Cloud providers, by contrast, concentrate massive sites in a small number of lower-density regions, where electricity, land and construction are cheaper and economies of scale are easier to achieve.

Third-party data centers, in other words, follow demand. They locate in urban markets where firms in finance, healthcare and IT value low latency, secure storage, and compliance with regulatory standards.

Using county-level data, the researchers modeled how population density, industry mix and operating costs predict where new centers enter. Every U.S. metro with more than 700,000 residents had at least one third-party provider, while many mid-sized cities had none.

ImageThis pattern challenges common assumptions. Third-party facilities are more distributed across urban America than prevailing narratives suggest.

Customer proximity matters because some sectors cannot absorb delay. In critical operations, even slight pauses can have real consequences. For hospital systems, lag can affect performance and risk exposure. And in high-frequency trading, milliseconds can determine whether value is captured or lost in a transaction.

“For industries where speed is everything, being too far from the physical infrastructure can meaningfully affect performance and risk,” Pan Fang says. “Proximity isn’t optional for sectors that can’t absorb delay.”

The Economics of Distance

For cloud providers, the picture looks very different. Their decisions follow a logic shaped primarily by cost and scale. Because cloud services can be delivered from afar, firms tend to build enormous sites in low-density regions where power is cheap and land is abundant.

These facilities can draw hundreds of megawatts of electricity and operate with far fewer employees than urban centers. “The cloud can serve almost anywhere,” Pan Fang says, “so location is a question of cost before geography.”

The study finds that cloud infrastructure clusters around network backbones and energy economics, not talent pools. Well-known hubs like Ashburn, Virginia — often called “Data Center Alley” — reflect this logic, having benefited from early network infrastructure that made them natural convergence points for digital traffic.

Local governments often try to lure data centers with tax incentives, betting they will create high-tech jobs. But the study suggests other factors matter more to cloud providers, including construction costs, network connectivity and access to reliable, affordable electricity.

When cloud centers need a local presence, distance can sometimes become a constraint. Providers often address this by working alongside third-party operators. “Third-party centers can complement cloud firms when they need a foothold closer to customers,” Pan Fang says.

That hybrid pattern — massive regional hubs complementing strategic colocation — may define the next phase of data center growth.

Looking ahead, shifts in remote work, climate resilience, energy prices and AI-driven computing may reshape where new facilities go. Some workloads may move closer to users, while others may consolidate into large rural hubs. Emerging data-sovereignty rules could also redirect investment beyond the United States.

“The cloud feels weightless,” Pan Fang says, “but it rests on real choices about land, power and proximity.”

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This article originally appeared on Rice Business Wisdom. Written by Scott Pett.

Pan Fang and Greenstein (2025). “Where the Cloud Rests: The Economic Geography of Data Centers,” forthcoming in Strategy Science.