A team from the University of Houston received a grant to continue its work on using AI and digital twin technology to better evaluate bridges in Texas. Photo via uh.edu

A University of Houston professor has received a grant from the Texas Department of Transportation (TxDOT) to improve the efficiency and effectiveness of how bridges are inspected in the state.

The $505,286 grant will support the project of Vedhus Hoskere, assistant professor in the Civil and Environmental Engineering Department, over three years. The project, “Development of Digital Twins for Texas Bridges,” will look at how to use drones, cameras, sensors and AI to support Texas' bridge maintenance programs.

“To put this data in context, we create a 3D digital representation of these bridges, called digital twins,” Hoskere said in a statement. “Then, we use artificial intelligence methods to help us find and quantify problems to be concerned about. We’re particularly interested in any structural problems that we can identify - these digital twins help us monitor changes over time and keep a close eye on the bridge. The digital twins can be tremendously useful for the planning and management of our aging bridge infrastructure so that limited taxpayer resources are properly utilized.”

The project began in September and will continue through August 2026. Hoskere is joined on the project by Craig Glennie, the Hugh Roy and Lillie Cranz Cullen Distinguished Chair at Cullen College and director of the National Center for Airborne Laser Mapping, as the project’s co-principal investigator.

According to Hoskere, the project will have implications for Texas's 55,000 bridges (more than twice as many as any other state in the country), which need to be inspected every two years.

Outside of Texas, Hoskere says the project will have international impact on digital twin research. Hoskere chairs a sub-task group of the International Association for Bridge and Structural Engineering (IABSE).

“Our international efforts align closely with this project’s goals and the insights gained globally will enhance our work in Texas while our research at UH contributes to advancing bridge digitization worldwide,” he said. “We have been researching developing digital twins for inspections and management of various infrastructure assets over the past 8 years. This project provides us an opportunity to leverage our expertise to help TxDOT achieve their goals while also advancing the science and practice of better developing these digital twins.”

Last year another UH team earned a $750,000 grant from the National Science Foundation for a practical, Texas-focused project that uses AI. The team was backed by the NSF's Convergence Accelerator for its project to help food-insecure Texans and eliminate inefficiencies within the food charity system.

UH Professor Vedhus Hoskere received a three-year, $505,286 grant from TxDOT for a bridge digitization project. Photo via uh.edu

The $63.5 million contract aims to support UH in developing analytical modeling and simulation platforms that help the U.S. Army make timely and effective decisions. Photo via uhsystem.edu

University of Houston lands $63.5M contract with DOD to develop tech for the 'future battlefield'

ready to innovate

The University of Houston was recently awarded its largest grant in history—this time, from the U.S. Department of Defense.

The $63.5 million contract aims to support UH in developing analytical modeling and simulation platforms that help the U.S. Army make timely and effective decisions, according to a release from UH.

Craig Glennie, professor of civil and environmental engineering and director of engineering defense research initiatives at the UH Cullen College of Engineering, who is leading the project, says the team's work will focus on creating tools for the time period before conflict begins.

“We are not looking at what happens once bullets start flying. We are looking at what happens during the competition and crisis phases, the buildup and the posturing and the projection of forces before you actually get to the point of armed conflict,” he says in a statement. “The Army needs tools to understand how they can effectively position themselves and project their force towards the adversary in such a manner that they can avoid armed conflict, or if that is not possible, be prepared for the onset of armed conflict.”

The team, which also includes members from the University of Massachusetts Amherst, New Mexico State University and other organizations, will work closely with the U.S. Army Combat Capabilities Development Command Analysis Center, known as DAC. They've been commissioned to help build realistic modeling, analysis and simulation tools that the Army can use in the "future battlefield."

DAC has named several high priority issues for the team including quantum technology, artificial intelligence, and machine learning.

“For example, we will look at the electromagnetic spectrum, at owning the airspace, and projecting that we have the radio frequency technology that is capable of jamming a neighbor’s signals," Glennie adds.

UH president Renu Khator says the university is honored to revive the contract.

“We understand the significance of this project in enhancing the Army’s decision-making capabilities, and we are proud to contribute to our nation’s security and strategic competitiveness," she said in a statement. "We look forward to the remarkable contributions that will emerge from this collaboration, strengthening the University of Houston’s commitment to driving innovation that matters.”

UH has inked a number of grants and contracts in recent months that are pushing innovative initiatives forward at the university.

Last month, UH received a $100,000 grant from the Baker Hughes Foundation to go toward workforce development programs, and environmental justice research at its Energy Transition Institute. The ETI was launched last year through a $10 million grant from Shell USA Inc. and Shell Global Solutions (US) Inc.

And earlier this month, Houston-based The Welch Foundation awarded its inaugural $5 million Catalyst for Discovery Program Grant to a new initiative led by Jeffrey Rimer, UH's Abraham E. Dukler Professor of Chemical Engineering. The grant launched the Welch Center for Advanced Bioactive Materials Crystallization, which will build upon Rimer's work relating to the use of crystals to help treat malaria and kidney stones.

Craig Glennie, professor of civil and environmental engineering and director of engineering defense research initiatives at the UH Cullen College of Engineering, is leading the project. Photo via uh.edu

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

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Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.