This week's roundup of Houston innovators includes John Higgins of illumiPure, Natara Branch of HX, and Daniel Murray of Covenant Underwriters. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from insurtech to entrepreneurship — recently making headlines in Houston innovation.

John Higgins, CEO of illumiPure

CleanWhite can quickly and continuously sanitize high-touch areas through its light-based technology. Photo via LinkedIn

Houston-based illumiPure recently announced that it has received a worldwide patent for its LED white light disinfectant earlier this year, known as CleanWhite. The product can quickly and continuously sanitize high-touch areas while a room remains occupied and has shown an elimination of 99 percent of surface bacteria, spores, mold, biofilms, and viruses including SARS-CoV-2 through light-based technology. It's intended to be used in areas like kitchens, restrooms, and locker rooms and is safe for humans and pets.

CleanWhite uses spikes of light wavelengths at 405 and 470 nanometers to kill surface pathogens. Unlike other products on the market, CleanWhite can emit these levels without also emitting a visible purple-violet light while also suppressing blue light wavelengths.

"CleanWhite features technology that makes it the first of its kind, achieving a sought-after solution to produce 405+470 nm blue light as white light," John Higgins, CEO of illumiPure, says in a statement. "As a result of this revolutionary finding, we anticipate the patent’s success across a myriad of industries, including education, healthcare, hospitality, and retail.” Click here to read more.

Natara Branch, CEO of Houston Exponential

Meet Natara Branch — the new CEO of HX. Photo courtesy of Natara Branch

Ever since she accepted the new position as CEO of Houston Exponential, Natara Branch has been on a listening tour of Houston's innovation ecosystem. Branch explains on the Houston Innovators Podcast that she has a passion for the city of Houston, and she's got open ears to anyone in the ecosystem who wants to contribute to the advancement of the city's tech ecosystem.

As she explains, she is getting her fair share of feedback — but she has an ask for anyone who she's met.

"I am challenging people. You're not just going to give me feedback and sit back and watch. You're going to participate," Branch says. "I have not met one person who doesn't want Houston to win — they wouldn't be here if they didn't." Click here to read more and listen to the podcast.

Daniel Murray, co-founder and chief underwriter of Covenant Underwriters

The emerging insurtech industry has a plethora of opportunities for job seekers and more. Photo courtesy

More than 100,000 Houstonians work in insurance, according to Daniel Murray, co-founder and chief underwriter of Covenant Underwriters, a Houston-based insurtech start-up, building e-commerce insurance products for underserved niches. But the 400-year-old industry is hungry for tech talent.

In a guest column for InnovationMap, Murray explains the need for tech and innovation within insurance — and the opportunity the industry has.

"The adage goes that everyone in the insurance industry was either born into it or tricked into it," he writes. "This may have applied to the last generation, but today’s insurance industry offers vast opportunities (including remote) for every discipline, especially for tech job seekers." Click here to read more.

The emerging insurtech industry has a plethora of opportunities for job seekers and more. Photo via Getty Images

Houston expert: The insurance biz is ripe for innovation — here's how to tap into it

guest column

The insurance industry is hungry for tech talent. This 400-year-old industry lays claim to many innovations from financial engineering to weather modeling and was among the first to widely adopt mainframe computing. However, while many sectors took up digital processes in the Internet Age, the $1.4 trillion insurance industry lost out on a generation of innovators to retail, social media, entertainment, and other financial services. Only recently have investors become wise to the massive opportunity of modernizing insurance.

More than 100,000 Houstonians work in insurance, mostly in sales and servicing of policies or claims. Many insurance agencies now employ IT professionals and graphic designers to support online experiences for customers and employees. Larger insurance companies are hiring data analysts, software developers, and cloud engineers to improve risk selection, mitigate losses, and drive efficiency. Such efforts to leverage technology in each function in the insurance value chain are broadly described by the term insurtech (or insuretech; it’s so novel that consensus has not been reached on its spelling).

The largest gathering of insurtech investors, entrepreneurs, and industry incumbents occurs at the InsureTech Connect conference. Last month saw nearly 10,000 insurtech leaders and hopefuls descend on Las Vegas for the 6th annual convention. Sound business models and partnerships with incumbents replaced the easy money and talk of disruption from prior years. Many speakers and panels highlighted the following opportunities for aspiring insurtech professionals:

​Embedded Insurance

Insurance has long been sold alongside other products, and omnipresent API ecosystems make the transaction that much more seamless. For a small premium, some insurtechs use embedded products that take the risk out of large purchases like event tickets, rentals, gadgets, and vacations. These companies need savvy designers and creative marketing pros to integrate their products with the right partners.

​Parametric Insurance

The fundamental principle of insurance is to make the policyholder whole after a loss, but agreeing on the amount of loss can take years and legal battles. Parametric insurance policies pay losses automatically based on pre-specified trigger events, such as a threshold based on wind speed or hail size. Cutting-edge products provide stability by tying coverage to indexes like oil price or crop yields and require experts in the underlying index to set the correct parameters.

​Internet of Things

Theoretically, more information will lead to more accurate prediction of insured loss. Cell phone geolocation, smart homes, and sensors on everything gives insurance companies a mountain of data. Translating all of this into actionable insights will require armies of data scientists. Machine learning algorithms, paired with good data, promise to uncover new ways to anticipate and avoid losses.

​Insurance Gigs

Many jobs in the burgeoning gig economy are related to insurance. For all the big data available, insurance companies still need ‘boots on the ground’ when inspecting a new policyholder’s property, assessing damage to a house or car, installing sensors, or responding to catastrophe. They especially need contract workers with drone licenses for inspecting roofs.

Insurtech is not disrupting insurance companies but transforming them to meet modern customer needs They can no longer succeed with just snappy TV ads and countless storefronts. Insurance quotes and claim payments need to be fast and fair. In an industry this large, a great idea that captures 1 percent of market share or improves efficiency by 1 percent can be lucrative. Today’s rate environment has cooled off insurtech valuations but not before 25 US and UK insurtech start-ups rose to billion-dollar unicorn status in the past decade.

The adage goes that everyone in the insurance industry was either born into it or tricked into it. This may have applied to the last generation, but today’s insurance industry offers vast opportunities (including remote) for every discipline, especially for tech job seekers.

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Daniel Murray is co-founder and chief underwriter of Covenant Underwriters, a Houston-based insurtech start-up, building e-commerce insurance products for underserved niches.

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Houston Intercontinental Airport's innovative upgrades ready for takeoff

coming soon

After almost five years of construction, passengers heading out of Bush Intercontinental Airport on October 22 will be the very first to experience the expanded, upgraded, and stylish Terminal D-West Pier, an expansion of the existing Terminal D.

The new terminal is part of a broader initiative, the IAH Terminal Redevelopment Program (ITRP), a $1.458 billion project aimed at modernizing the airport's international travel capabilities. ITRP is the single largest capital improvement project developed by Houston Airports and include the refresh of the existing Terminal D, completed in 2023; the expansion of Terminal D with a new D-West Pier, which will be completed this fall 2024; and a new International Central Processor, slated for winter of 2024 and summer of 2025. More than 3,000 people spent more than one million hours on the construction project.

Terminal D-West Pier features six new gates — D1 through D6 — that can simultaneously accommodate wide-body aircraft or converted to accommodate 10 narrow-body airplanes. The expanded terminal with its new capabilities supports increasing demand from passengers and airlines and should enhance the overall travel experience.

The new terminal is part of a broader initiative, the IAH Terminal Redevelopment Program (ITRP), a $1.458 billion project aimed at modernizing the airport's international travel capabilities. Photo courtesy of Houston Airports

In addition to adding 160,000-square-feet, the new wing also boasts eight new, Houston-inspired works by local artists. Those kind of details are why the Houston airport system won Best Airport Art & Entertainment Program in the prestigious Skytrax awards.

The airport's 250 newly-hired employees will work among 16 new retail and dining concessions concepts in the Terminal D-West Pier. Passengers can dine at Houston Supply Co., which opened last month. Local restaurants The Kitchen and The Annie, along with popular national brands Popeyes, Einstein Bros. Bagels, Jamba Juice, Be Relax, Jetero Market, Semi-Sweet Confectionary, and a Lego Store will open for business on October 22.

The new wing also boasts eight new, Houston-inspired works by local artists. Photo courtesy of Houston Airports

"We are focused on improving the overall passenger experience at the airport — from parking and traffic to providing modern terminals with the right amenities. This project is a major investment in our city's future," Houston Mayor John Whitmire said in a statement. "The newly expanded international terminal enhances Houston's reputation as a world-class city and provides a boost to our economy, supporting jobs and attracting more visitors from around the globe."

The new terminal offers a host of other amenities designed to make passengers' experiences more comfortable. They include a mother's room, a sensory room, a child's play area, and expanded men's, women's, and family restrooms. The restrooms utilize smart technology sensors that trigger soap and water. Door locks alert to whether a restroom stall is vacant or occupied and soft LED lighting accentuates floor-to-ceiling photography spotlighting Houston's natural beauty.

The new wing has 16 new retail and dining concessions concepts. Photo courtesy of Houston Airports

An International Arrivals corridor provides views of the airfield, the concourse, and large-scale photography inspired by Houston.

More than 500 modern and comfortable seats, including chairs, cushioned benches, and cozy loungers, featuring cup holders and charging capabilities, are present inside the terminal.

"We are excited to share this milestone with the residents of Houston," said Jim Szczesniak, director of aviation for Houston Airports. "The opening of the Terminal D-West Pier is a testament to the hard work and dedication of our team and our partners. This world-class facility will provide a seamless and efficient travel experience for millions of passengers each year. The new pier will provide the necessary capacity so that Houston can continue to attract more nonstop flights to cities around the globe."

New features include a mother's room, a sensory room, a child's play area, and expanded men's, women's, and family restrooms. Photo courtesy of Houston Airports

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This article originally ran on CultureMap.

12 health tech startups named to Houston accelerator's next bootcamp

onboarding

Twelve promising health tech startups have been selected for the annual bootcamp at the Texas Medical Center.

TMC's Accelerator for HealthTech selected 12 companies from around the world and across specialties for the opportunity. Following the bootcamp, TMC will move forward a selection of startups to join its accelerator.

"Houston, a thriving hub for innovation, is rapidly becoming the destination of choice for healthtech companies," reads a statement from TMC. "With the Texas Medical Center at its heart, the city offers unparalleled resources, cutting-edge research facilities, and a collaborative spirit that fosters growth. This environment not only attracts startups but also provides them with the necessary tools to navigate the complex landscape of healthcare commercialization."

Through the bootcamp, the participants will engage with advisors and industry experts, refine their business models, prepare for market entry, and have opportunities for collaboration with the TMC's member organizations.

The selected bootcamp companies, according to TMC, include:

  • Alyf, founded in Newport Beach, California, has developed a personalized cardiac care system that brings patients and providers together with real-time, AI-driven insights, enabling them to monitor, track, and improve cardiac health outcomes collaboratively.
  • Seoul, South Korea-based Deepmetrics leverages artificial intelligence to provide ICU smart care services that optimize medical device settings, such as mechanical ventilators, to reduce mortality and shorten the length of stay for critically ill patients worldwide.
  • EquityQuotient, from New York City, is a healthcare intelligence platform that automates compliance and provides actionable insights by aggregating public, private, and first-party data, using proprietary analytics to help leaders address disparities, improve outcomes, and lower care costs.
  • Also from New York City, Ethermed's AI-powered solution streamlines prior authorizations, eliminating up to 90 percent of auths and 70 percent of the labor involved. Ethermed requires no workflow changes, is fully auditable, and offers aligned incentives from a mission-driven, human-focused company.
  • Fibricheck, based in Hasselt, Belgium, transforms ordinary smartphones into regulated digital heart rhythm monitors, offering unparalleled access to cardiovascular diagnostics for patients and streamlined workflows for physicians.
  • Austin-based NearWave has developed a non-invasive, AI-powered handheld imaging device that can predict breast cancer therapy response within seven days.
  • Pragmaclin, founded in Newfoundland, Canada, developed a cutting-edge PRIMS (Parkinson’s Remote Interactive Management System) that leverages depth cameras and machine learning to monitor and assess Parkinson’s Disease symptoms, offering healthcare professionals remote and in-clinic insights to enhance treatment decisions.
  • Somnair, a Baltimore, Maryland, company, is developing a non-invasive neurostimulation oral appliance for treating obstructive sleep apnea, offering a sleek, retainer-sized device that provides an effective alternative to CPAP or invasive surgery for millions of patients.
  • Vancouver, Canada-headquartered Total Flow Medical is developing solutions to enhance the quality of care and life for patients requiring the use of a heart-lung machine during surgery or life support.
  • Tympulse, hailing from Dublin, Ireland, is commercializing TympanoColl, an innovative and disruptive solution for eardrum (Tympanic Membrane) repair in an outpatient setting through the ear canal.
  • Perth, Australia-based Vital Trace is developing a continuous lactate monitor for real-time, accurate detection of fetal distress.
  • New York City's WorkUp is a healthcare-specific talent pipeline management platform that connects students with tailored resources for their clinical career journey, providing personalized support as their needs evolve.

University of Houston-founded company secures $2.5M in NIH grant funding

all in the timing

You could say that the booming success of Houston biotech company CellChorus owes very much to auspicious TIMING. Those six letters stand for Time-lapse Imaging Microscopy In Nanowell Grids, a platform for dynamic single-cell analysis.

This week, CellChorus announced that the company, along with The University of Houston, has been awarded up to $2.5 million in funding from the National Center for Advancing Translational Sciences (NCATS) at the National Institute of Health. A $350,000 Phase I grant is already underway. Once predetermined milestones are achieved, this will lead to a two-year $2.1 million Phase II grant.

The TIMING platform was created by UH Single Cell Lab researchers Navin Varadarajan and Badri Roysam. TIMING generates high-throughput in-vitro assays that quantitatively profile interactions between cells on a large scale, particularly what happens when immune cells confront target cells. This has been especially useful in the realm of immuno-oncology, where it has demonstrated its power in designing novel therapies, selecting lead candidates for clinical trials and evaluating the potency of manufactured cells.

“By combining AI, microscale manufacturing and advanced microscopy, the TIMING platform yields deep insight into cellular behaviors that directly impact human disease and new classes of therapeutics,” says Rebecca Berdeaux, chief scientific officer at CellChorus. “The generous support of NCATS enables our development of computational tools that will ultimately integrate single-cell dynamic functional analysis of cell behavior with intracellular signaling events.”

Houston’s CellChorus Innovation Lab supports both the further development of TIMING and projects for early-access customers. Those customers include top-25 biopharmaceutical companies, venture-backed biotechnology companies, a leading comprehensive cancer center and a top pediatric hospital, says CEO Daniel Meyer.

CellChorus’s publications include papers written in collaboration with researchers from the Baylor College of Medicine, Houston Methodist, MD Anderson, Texas Children’s Hospital, the University of Texas and UTHealth in journals including Nature Cancer, Journal of Clinical Investigation and The Journal for ImmunoTherapy of Cancer.

The new Small Business Technology Transfer (STTR) award will specifically support the development of a scalable integrated software system conceived with the goal of analyzing cells that are not fluorescently labeled. This label-free analysis will be based on new AI and machine learning (ML) models trained on tens of millions of images of cells.

“This is an opportunity to leverage artificial intelligence methods for advancing the life sciences,” says Roysam. “We are especially excited about its applications to advancing cell-based immunotherapy to treat cancer and other diseases.”

The Houston-born-and-bred company couldn’t have a more appropriate home, says Meyer.

“Houston is a premier location for clinical care and the development of biotechnology and life sciences technologies. In particular, Houston has established itself as a leader in the development and delivery of immune cell-based therapies,” the CEO explains. “As a spin-out from the Single Cell Lab at the University of Houston, we benefit from working with world-class experts at local institutions.”

In May, the company received a similar $2.5 million SBIR grant from NCATS at the NIH. Also this summer, CellChorus's technology was featured in Nature Cancer.