3 Houston innovators to know this week

who's who

This week's innovators to know in Houston includes Marcelo Cordini of December Labs, Courtney Sikes Longmore of Pure Palate, and Josh Ruben of Z3VR. Photos courtesy

Editor's note: In today's Monday roundup of Houston innovators, I'm introducing you to three innovators representing a diverse set of industries — from virtual reality to software development — all making headlines in Houston this week.

Marcelo Cordini, co-founder of December Labs

Marcelo Cordini, co-founder of December Labs, joins the Houston Innovators Podcast to discuss the unique service his company provides an evolving tech workforce. Photo courtesy of December Labs

Marcelo Cordini realized that nowadays, software developers are like rockstars. They can make or break a startup or technology's success and finding the best development team can be hard to do. But hiring and cultivating software talent is a specialty most companies — big or small — has the time or expertise to handle. That's where December Labs comes in.

"We are always learning new technologies — that's our focus," Cordini says. "If you have a big company focused on real estate, your focus is on real estate — not technology. So, if you partner with a company like us, it will give you that value to have someone who knows how to hire developers and how to train them."

Cordini joined the Houston Innovators Podcast last week to discuss the unique service his company provides and the state of software employment is in these days. Read more and stream the episode.

Courtney Sikes Longmore, founder at Pure Palate

Women in the work place have been hit the hardest by the pandemic. Photo via Pexels

According to Labor Department statistics, 1.1 million people left the workforce in August and September, and of that 800,000 were women. This data wasn't surprising to Courtney Sikes Longmore, an entrepreneur and founder of Pure Palate — however it was a call to action. She teamed up with Sesh Coworking to host a panel (click here to stream) to discuss how COVID-19 has disproportionately affected women and co-wrote a guest article with Maggie Segrich on the subject too.

"A decline of women in the labor force, on teams, in leadership positions and in decision-making roles compromises not just our economy's recovery and productivity, but also the innovation and effectiveness in industry, competitiveness on a global scale, aspirations of future generations of women, and society as a whole," they write. Read more.

Josh Ruben, CEO of Z3VR

Houston-based Z3VR has been granted $500,000 to work or virtual reality applications in space. Photo courtesy of Z3VR

The Houston-based Translational Research Institute for Space Health is always trying to find and support innovations that will help current and future astronauts, and Josh Ruben's company, Z3VR, was a perfect fit to work on virtual reality applications in space. The company received a $500,000 grant from TRISH last month to continue exploring how the wide world of virtual reality can boost mental and physical health for astronauts on a mission to Mars.

"This TRISH funding means the world," he says. "Not only do we have these partnerships within NASA, which we expect will really help address these problems, but we are already taking the funds and putting them to work in the US health care system." Read more.

Women in the work place have been hit the hardest by the pandemic. Houston experts discuss the effect in a guest column and a panel hosted by Sesh Coworking on Oct. 14. Photo via Pexels

Houston experts discuss the toll the pandemic has taken on women in the workplace

guest column

The shutdown of our economy, schools and childcare systems has created a wildfire that is raging across our nation, disproportionately impacting women, radically shifting social values, and compromising our nation's post-pandemic recovery.

While women have made great gains in the last few decades towards gender equality, the pandemic has exacerbated some of the larger remaining issues — time spent in unpaid work or "invisible labor," political under-representation, violence against women, limited access to capital and the gender pay gap) — and, according to a recent analysis by McKinsey, without serious intervention, is at risk of wiping $1 trillion off global GDP by 2030.

While everyone has suffered during the pandemic, women have found themselves under disproportionate pressure — women's jobs have become more vulnerable (women are 1.8 times more likely to lose their jobs than men), female dominated industries (restaurants, child-care, leisure and hospitality, health care, and education) have been hardest hit, and women of color in particular are more likely to be laid off or furloughed (leanin.org - women in workplace study).

These inequities, coupled with the increased stress and labor of child-care while "working from home" have placed an overwhelming strain on the working parents, and in particular mothers, of America. The mental and emotional health loads of working parents have been pushed to their limits and with that working families are re-prioritizing their values and spending habits faster than ever before.

Is it any surprise that during the pandemic the need for families to quickly adapt to the new economy plus the inequity of women's wages versus men is driving more and more women to sacrifice their careers and dreams to ease the increased burdens the pandemic has inflamed?

Leanin.org and McKinsey's Women in the Workplace study polled over 40,000 employees across 317 companies between May and Aug 2020, and found that more than 1 in 4 women are considering downshifting their careers or leaving the workforce entirely, according Leanin.org and McKinsey.

Labor Department statistics show that this inclination is already in action: In August and September 1.1 million people left the workforce, and of that 800,000 were women. According to a recent analysis by the National Women's Law Center of those 800,000 women — 324,000 were Latinas and 58,000 were Black women. Now compare that to the 216,000 men who left the job market during August and September.

This exodus of women leaving the workforce has broad reaching and long-lasting effects on not just female-owned businesses and women in the workplace – it is an issue that impacts every person at every level of business. Women's rise in participation in the labor force is not just good for women, it is good for business: directly impacting our GDP and a rise in wages for everyone, not just women.

A decline of women in the labor force, on teams, in leadership positions and in decision-making roles compromises not just our economy's recovery and productivity, but also the innovation and effectiveness in industry, competitiveness on a global scale, aspirations of future generations of women, and society as a whole.

If "women hold up half the sky" you could certainly argue that the sky is now falling. So, the question is – what can we do about it? And that is a question we intend to tackle in depth on Wednesday, October 14, at 1 pm in a virtual town hall with inspiring women who are already paving the road to our recovery: Elizabeth Gore of Hello Alice, Cate Luzio of Luminary; Cathy Mchorse of United Way of Greater Austin; Lucie Green of Light Years. Click here to register.

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Maggie Segrich is co-founder and CFO of Sesh Coworking and Courtney Sikes Longmore is the founder at Pure Palate. The two female innovators will be on the panel of the online event.

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Rice University researchers unveil new model that could sharpen MRI scans

MRI innovation

Researchers at Rice University, in collaboration with Oak Ridge National Laboratory, have developed a new model that could lead to sharper imaging and safer diagnostics using magnetic resonance imaging, or MRI.

In a study recently published in The Journal of Chemical Physics, the team of researchers showed how they used the Fokker-Planck equation to better understand how water molecules respond to contrast agents in a process known as “relaxation.” Previous models only approximated how water molecules relaxed around contrasting agents. However, through this new model, known as the NMR eigenmodes framework, the research team has uncovered the “full physical equations” to explain the process.

“The concept is similar to how a musical chord consists of many notes,” Thiago Pinheiro, the study’s first author, a Rice doctoral graduate in chemical and biomolecular engineering and postdoctoral researcher in the chemical sciences division at Oak Ridge National Laboratory, said in a news release. “Previous models only captured one or two notes, while ours picks up the full harmony.”

According to Rice, the findings could lead to the development and application of new contrast agents for clearer MRIs in medicine and materials science. Beyond MRIs, the NMR relaxation method could also be applied to other areas like battery design and subsurface fluid flow.

“In the present paper, we developed a comprehensive theory to interpret those previous molecular dynamics simulations and experimental findings,” Dilipkumar Asthagiri, a senior computational biomedical scientist in the National Center for Computational Sciences at Oak Ridge National Laboratory, said in the release. ”The theory, however, is general and can be used to understand NMR relaxation in liquids broadly.”

The team has also made its code available as open source to encourage its adoption and further development by the broader scientific community.

“By better modeling the physics of nuclear magnetic resonance relaxation in liquids, we gain a tool that doesn’t just predict but also explains the phenomenon,” Walter Chapman, a professor of chemical and biomolecular engineering at Rice, added in the release. “That is crucial when lives and technologies depend on accurate scientific understanding.”

The study was backed by The Ken Kennedy Institute, Rice Creative Ventures Fund, Robert A. Welch Foundation and Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory.

Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

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