A company in Houston has discovered an efficient way to manufacture a game-changing antioxidant that does wonders for the body. Image via continualg.com

Rajan Shah, an MIT-trained chemical engineer, brought his patented manufacturing process 20 years in the making and from an ocean away to Houston with one goal in mind: to take what he calls the body's "master antioxidant" to market.

Known as Continual G, Shah's product packs the supplement known as Glyteine into a powder form that when mixed with water can be consumed as a citrus-flavored beverage. Glyteine is known to increase cellular glutathione levels in the body, which can boost immunity, support sports activity and recovery, and address a variety of oxidative stressors that impact the body and brain as humans age.

Shah and a team of four at his INID Research Lab in Cypress are the only company in the world producing the dipeptide in this accessible format.

"The fact that the only way to increase cellular glutathione is with Glyteine has been known for almost 40 years," Shah says. "The problem is how to make it in a way which becomes cost effective so that it can be sold and people can afford to buy it."

It was this problem that Shah and a team at the University of New South Wales in Australia spent about 13 years tackling, as the creation the Glyteine — which requires the rare catalyzation of enzymes — would leave researchers with expensive byproduct that would result in high costs for little product. But in 2005, the university was awarded a patent for the manufacturing process the group developed that essentially eliminated waste. Instead, they were able to recycle the by product to create even more of the powerful protein.

"Only when we could solve these problems did it become affordable. Then you are using your raw materials to produce your product and nothing else. We were able to recycle," Shah explains. "That is what took the time and that is what made it affordable cost wise."

Next the group spent years scaling the production of the compound and learning how to best deploy it to a customer base. Initially, the group hoped to simply sell the protein to large supplement companies, such as GNC. But when they were met with reservations due to the product's newness, they pivoted.

Houston's large pool of chemical manufacturing workers and easy access to water (a key ingredient in Continual G's production) attracted the Aussie-based scientist. And in 2017, Shah took the practices from down under to the Bayou City just days before Hurricane Harvey hit.

Today the group is producing about a quarter of a million packets of Continual G each month with the help of an outsourced, Texas-based manufacturer who assists the group of engineers in transposing the compound into a drinkable powder. They operate out of a state-of-the-art, 14,000-square-foot manufacturing facility and hope to scale up again.

"Everyone involved with this endeavor has a heartfelt commitment," Shah adds in a statement. "Glyteine has profound implications for human health. That alone has made it well worth the effort to overcome every challenge we have faced and continue to face."

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Texas falls to bottom of national list for AI-related job openings

jobs report

For all the hoopla over AI in the American workforce, Texas’ share of AI-related job openings falls short of every state except Pennsylvania and Florida.

A study by Unit4, a provider of cloud-based enterprise resource planning (ERP) software for businesses, puts Texas at No. 49 among the states with the highest share of AI-focused jobs. Just 9.39 percent of Texas job postings examined by Unit4 mentioned AI.

Behind Texas are No. 49 Pennsylvania (9.24 percent of jobs related to AI) and No. 50 Florida (9.04 percent). One spot ahead of Texas, at No. 47, is California (9.56 percent).

Unit4 notes that Texas’ and Florida’s low rankings show “AI hiring concentration isn’t necessarily tied to population size or GDP.”

“For years, California, Texas, and New York dominated tech hiring, but that’s changing fast. High living costs, remote work culture, and the democratization of AI tools mean smaller states can now compete,” Unit4 spokesperson Mark Baars said in a release.

The No. 1 state is Wyoming, where 20.38 percent of job openings were related to AI. The Cowboy State was followed by Vermont at No. 2 (20.34 percent) and Rhode Island at No. 3 (19.74 percent).

“A company in Wyoming can hire an AI engineer from anywhere, and startups in Vermont can build powerful AI systems without being based in Silicon Valley,” Baars added.

The study analyzed LinkedIn job postings across all 50 states to determine which ones were leading in AI employment. Unit4 came up with percentages by dividing the total number of job postings in a state by the total number of AI-related job postings.

Experts suggest that while states like Texas, California and Florida “have a vast number of total job postings, the sheer volume of non-AI jobs dilutes their AI concentration ratio,” according to Unit4. “Moreover, many major tech firms headquartered in California are outsourcing AI roles to smaller, more affordable markets, creating a redistribution of AI employment opportunities.”

Houston energy trailblazer Fervo closes $462 million Series E

Fresh Funds

Houston-based geothermal energy company Fervo Energy has closed an oversubscribed $462 million series E funding round, led by new investor B Capital.

“Fervo is setting the pace for the next era of clean, affordable, and reliable power in the U.S.,” Jeff Johnson, general partner at B Capital, said in a news release.

“With surging demand from AI and electrification, the grid urgently needs scalable, always-on solutions, and we believe enhanced geothermal energy is uniquely positioned to deliver. We’re proud to support a team with the technical leadership, commercial traction, and leading execution capabilities to bring the world’s largest next-generation geothermal project online and make 24/7 carbon-free power a reality.”

The financing reflects “strong market confidence in Fervo’s opportunity to make geothermal energy a cornerstone of the 24/7 carbon-free power future,” according to the company. The round also included participation from Google, a longtime Fervo Partner, and other new and returning investors like Devon Energy, Mitsui & Co., Ltd., Mitsubishi Heavy Industries and Centaurus Capital. Centaurus Capital also recently committed $75 million in preferred equity to support the construction of Cape Station Phase I, Fervo noted in the release.

The latest funding will support the continued buildout of Fervo’s Utah-based Cape Station development, which is slated to start delivering 100 MW of clean power to the grid beginning in 2026. Cape Station is expected to be the world's largest next-generation geothermal development, according to Fervo. The development of several other projects will also be included in the new round of funding.

“This funding sharpens our path from breakthrough technology to large-scale deployment at Cape Station and beyond,” Tim Latimer, CEO and co-founder of Fervo, added in the news release. “We’re building the clean, firm power fleet the next decade requires, and we’re doing it now.”

Fervo recently won Scaleup of the Year at the 2025 Houston Innovation Awards, and previously raised $205.6 million in capital to help finance the Cape Station earlier this year. The company fully contracted the project's capacity with the addition of a major power purchase agreement from Shell this spring. Fervo’s valuation has been estimated at $1.4 billion and includes investments and support from Bill Gates.

“This new investment makes one thing clear: the time for geothermal is now,” Latimer added in a LinkedIn post. “The world desperately needs new power sources, and with geothermal, that power is clean and reliable. We are ready to meet the moment, and thrilled to have so many great partners on board.”

---

This article originally appeared on EnergyCapitalHTX.com.

Baylor center receives $10M NIH grant to continue rare disease research

NIH funding

Baylor College of Medicine’s Center for Precision Medicine Models received a $10 million, five-year grant from the National Institutes of Health last month that will allow it to continue its work studying rare genetic diseases.

The Center for Precision Medicine Models creates customized cell, fly and mouse models that mimic specific genetic variations found in patients, helping scientists to better understand how genetic changes cause disease and explore potential treatments.

The center was originally funded by an NIH grant, and its models have contributed to the discovery of several new rare disease genes and new symptoms caused by known disease genes. It hosts an online portal that allows physicians, families and advocacy groups to nominate genetic variants or rare diseases that need further investigation or new treatments.

Since its founding in 2020, it has received 156 disease/variant nominations, accepted 63 for modeling and produced more than 200 precision models, according to Baylor.

The center plans to use the latest round of funding to bring together more experts in rare disease research, animal modeling and bioinformatics, and to expand its focus and model more complex diseases.

Dr. Jason Heaney, associate professor in the Department of Molecular and Human Genetics at BCM, serves as the lead principal investigator of the center.

“The Department of Molecular and Human Genetics is uniquely equipped to bring together the diverse expertise needed to connect clinical human genetics, animal research and advanced bioinformatics tools,” Heaney added in the release. “This integration allows us to drive personalized medicine forward using precision animal models and to turn those discoveries into better care for patients.”