CaringBand is using a simple technology to better connect family and friends to the ones they love. Courtesy of CaringBand

When Charley Donaldson's mother-in-law was battling cancer, he and his wife had great support from their friends and family. But they also knew there were a lot of people who cared about them who didn't know what to say or do during such a challenging time.

"It's like, you want to show people that you care about them, but you don't want to interrupt their day, or you don't want to be a burden to them if they aren't up to company," Donaldson says about the common reactions he heard from others – and often felt himself when he had friends going through similar struggles. "There had to be a way to share the idea of, 'Hey, I'm thinking about you.'"

It took three years of rattling around that idea before CaringBand came to life. The light-up bracelet is Bluetooth enabled, and connects to a mobile app. A person gives the bracelet to a loved one, who then pairs it with his or her smartphone. App users can send and receive pre-set messages of encouragement to and from other app users.

Those wearing a CaringBand bracelet get alerted by a blinking light or vibration that lets them know someone is thinking about them. The wearer then reads these encouraging messages on the CaringBand app when convenient and with no need to respond.

"When we pilot tested it, we were super excited to find out what we thought was validated," says Donaldson. "People really loved knowing that others were keeping them in their thoughts, and those who sent messages liked that they didn't have to worry about saying or doing the wrong thing."

Donaldson says he wanted The CaringBand to be as easy as possible for people to use, and also ensure that it was a solid support system. When someone is going through medical treatments, he knows that can be exhausting, and he also realizes that friends and family want to be able to do something, anything, to express their love and support.

"If you're a normal, compassionate person, you want to show you care about someone," he says. "This lets you do that in your own way."

And while it might sound like The CaringBand is designed to make the senders of messages feel better about offering a good thought for someone, Donaldson says those going through treatments have really loved seeing their bracelets light to up to tell them they're on someone's mind. That small show of support has made a big difference, they told Donaldson in surveys.

"She is sitting on the couch having so much fun reading her messages," says one user in a testimonial. "The smile on her face is priceless." "People tell you they think of you and pray for you all the time," read another. "The bracelet gives you a reminder that they really are."

"We made it super easy," he says. "It's a hardware to software solution and we wanted to erase as many friction points as possible in its creation. This is two touches of a smart phone."

Currently, the CaringBand app is live and functional. The bracelet is still in developmental stages, and Donaldson says the team is working with individuals and groups such as the Tyler Robinson Foundation to further test it. The bracelet should be a go for full distribution and sale by the first quarter of 2020.

"Obviously, this doesn't replace driving over to see someone or having a cup of coffee with a friend," says Donaldson. "But it is a great supplemental tool to show your love and care when you might not know what else to do."

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.