Houston e-commerce startup cracks Inc. 5000 — here's who makes the 2022 list

by the numbers

GoExpedi, an e-commerce software company, represents Houston's tech and startup ecosystem on this year's Inc. 5000. Image courtesy of GoExpedi

In the latest edition of its roundup of fastest growing privately held companies, Inc. magazine has recognized dozens of Houston organizations.

Houston startup GoExpedi, an industrial supply chain and analytics company, is the highest ranking local tech company on the list. GoExpedi ranked No. 675 in the 2022 edition of Inc. 5000, with a 924 percent growth rate between 2018 and 2021.

"The team at GoExpedi is honored to rank number 675 among America's Fastest-Growing Private Companies on the Inc. 5000 Annual List," says Tim Neal, CEO of GoExpedi, in a news release. "GoExpedi has grown exponentially since launching in 2017 due to our forward-thinking and innovative supply chain solutions."

Real estate firm Disrupt Equity is the overall top Houston performer, and the sole Houston company to break the top 200 in the report. The company charted an impressive 2,975 percent growth rate between 2018 and 2021. The firm pushes complete multifamily real estate investment offerings that are earmarked as able to achieve and even exceed projections, clearly a safe haven in one of the biggest — and hottest — real estate markets in the entire nation.

Disrupt claims an impressive ROI for clients: The company boasts a "proven track record with over a dozen full cycle exits averaging over 36 percent annualized return to investors," director of investor relations, Tarek Moussa, tells CultureMap.

"We could not be more ecstatic to hear that Disrupt Equity has been announced as the fastest growing company in Houston by Inc 5000," says Feras Moussa, Disrupt's managing partner, in a statement. "We believe success in real estate, especially in today's economic environment, comes from being a great operator and having a strong team behind you. We believe this has been a large contributor to our success and helps us to continue to provide incredible passive real estate investment opportunities to our investors."

Speaking of real estate, another Houston firm performed well. Construction Concepts, which specializes in commercial design and build in Houston and Austin, ranked No. 497 overall, with 1,251 percent growth over three years. 5111 VENTURES, listed as a full-service real estate brokerage firm specializing in technology-driven residential and commercial sales and consulting services, was No. 558 with 1125 percent growth over three years.

In all, 468 Texas-based companies made this year’s Inc. 5000. Dallas-Fort Worth firms performed especially well:

  • No. 13 StaffDNA, Plano, 19,699 percent growth rate
  • No. 17 Blue Hammer Roofing, Dallas, 15,911 percent growth rate
  • No. 116 TimelyMD, Fort Worth, 3,852 percent growth rate
  • No. 142 Curis Functional Health, Farmers Branch, 3,380 percent growth rate
  • No. 148 SmartLight Analytics, Plano, 3,317 percent growth rate
  • No. 168 Digital Thrive, Dallas, 3,056 percent growth rate
  • No. 172 Forester Haynie, Dallas, 2,984 percent growth rate

Here are the other Texas companies appearing in the state’s top 20 and in the top 500 overall.

  • No. 60 AdOutreach, Austin, 6,052 percent growth rate
  • No. 62 Webforce, Austin, 6,009 percent growth rate
  • No. 117 Homestead Brands, Austin, 3,839 percent growth rate
  • No. 174 Disrupt Equity, Houston, 2,975 percent growth rate
  • No. 188 24HourNurse Staffing, Pittsburg, 2,801 percent growth rate
  • No. 201, Everly Health, Austin, 2,643 percent growth rate
  • No. 209, Texas Solar Integrated, San Antonio, 2,559 percent growth rate
  • No. 212, Apple Blvd Boutique, Frisco, 2,555 percent growth rate
  • No. 285 Element 26, Austin, 1,948 percent growth rate
  • No. 312 Boostlingo, Austin, 1,820 percent growth rate
  • No. 317 Cover Desk, Austin, 1,800 percent growth rate
  • No. 325 Canopy Management, Austin, 1,758 percent growth rate
  • No. 497 Construction Concepts, Houston, 1,251 percent growth rate

Companies on the 2022 Inc. 5000 are ranked by percentage growth in revenue from 2018 to 2021. To qualify for the list, a company must have been founded and been generating revenue by March 31, 2018. The company also must have been U.S.-based, privately held, for-profit, and independent as of December 31, 2021. The minimum revenue required for 2018 was $100,000; the minimum for 2021 was $2 million.

"The accomplishment of building one of the fastest-growing companies in the U.S., in light of recent economic roadblocks, cannot be overstated," says Scott Omelianuk, editor in chief of Inc. "Inc. is thrilled to honor the companies that have established themselves through innovation, hard work, and rising to the challenges of today."

A total of 90 Houston-area companies made the list last year, including Homestead Brands, Onit, GoCo.io, Velentium, Softeq, Poetic, Techwave, and more.

------

This article originally ran on CultureMap. Steven Devadanam and Natalie Harms also contributed to this story.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Houston founder on shaping the future of medicine through biotechnology and resilience

Guest Column

Living with chronic disease has shaped my life in profound ways. My journey began in 5th grade when I was diagnosed with Scheuermann’s disease, a degenerative disc condition that kept me sidelined for an entire year. Later, I was diagnosed with hereditary neuropathy with liability to pressure palsies (HNPP), a condition that significantly impacts nerve recovery. These experiences didn’t just challenge me physically, they reshaped my perspective on healthcare — and ultimately set me on my path to entrepreneurship. What started as personal health struggles evolved into a mission to transform patient care through innovative biotechnology.

A defining part of living with these conditions was the diagnostic process. I underwent nerve tests that involved electrical shocks to my hands and arms — without anesthesia — to measure nerve activity. The pain was intense, and each test left me thinking: There has to be a better way. Even in those difficult moments, I found myself thinking about how to improve the tools and processes used in healthcare.

HNPP, in particular, has been a frustrating condition. For most people, sleeping on an arm might cause temporary numbness that disappears in an hour. For me, that same numbness can last six months. Even more debilitating is the loss of strength and fine motor skills. Living with this reality forced me to take an active role in understanding my health and seeking solutions, a mindset that would later shape my approach to leadership.

Growing up in Houston, I was surrounded by innovation. My grandfather, a pioneering urologist, was among the first to introduce kidney dialysis in the city in the 1950s. His dedication to advancing patient care initially inspired me to pursue medicine. Though my path eventually led me to healthcare administration and eventually biotech, his influence instilled in me a lifelong commitment to medicine and making a difference.

Houston’s thriving medical and entrepreneurial ecosystems played a critical role in my journey. The city’s culture of innovation and collaboration provided opportunities to explore solutions to unmet medical needs. When I transitioned from healthcare administration to founding biotech companies, I drew on the same resilience I had developed while managing my own health challenges.

My experience with chronic disease also shaped my leadership philosophy. Rather than accepting diagnoses passively, I took a proactive approach questioning assumptions, collaborating with experts, and seeking new solutions. These same principles now guide decision-making at FibroBiologics, where we are committed to developing groundbreaking therapies that go beyond symptom management to address the root causes of disease.

The resilience I built through my health struggles has been invaluable in navigating business challenges. While my early career in healthcare administration provided industry insights, launching and leading companies required the same determination I had relied on in my personal health journey.

I believe the future of healthcare lies in curative treatments, not just symptom management. Fibroblast cells hold the promise of engaging the body’s own healing processes — the most powerful cure for chronic diseases. Cell therapy represents both a scientific breakthrough and a significant business opportunity, one that has the potential to improve patient outcomes while reducing long-term healthcare costs.

Innovation in medicine isn’t just about technology; it’s about reimagining what’s possible. The future of healthcare is being written today. At FibroBiologics, our mission is driven by more than just financial success. We are focused on making a meaningful impact on patients’ lives, and this purpose-driven approach helps attract talent, engage stakeholders, and differentiate in the marketplace. Aligning business goals with patient needs isn’t just the right thing to do, it’s a powerful model for sustainable growth and lasting innovation in biotech.

---

Pete O’Heeron is the CEO and founder of FibroBiologics, a Houston-based regenerative medicine company.


Houston researchers make headway on affordable, sustainable sodium-ion battery

Energy Solutions

A new study by researchers from Rice University’s Department of Materials Science and NanoEngineering, Baylor University and the Indian Institute of Science Education and Research Thiruvananthapuram has introduced a solution that could help develop more affordable and sustainable sodium-ion batteries.

The findings were recently published in the journal Advanced Functional Materials.

The team worked with tiny cone- and disc-shaped carbon materials from oil and gas industry byproducts with a pure graphitic structure. The forms allow for more efficient energy storage with larger sodium and potassium ions, which is a challenge for anodes in battery research. Sodium and potassium are more widely available and cheaper than lithium.

“For years, we’ve known that sodium and potassium are attractive alternatives to lithium,” Pulickel Ajayan, the Benjamin M. and Mary Greenwood Anderson Professor of Engineering at Rice, said in a news release. “But the challenge has always been finding carbon-based anode materials that can store these larger ions efficiently.”

Lithium-ion batteries traditionally rely on graphite as an anode material. However, traditional graphite structures cannot efficiently store sodium or potassium energy, since the atoms are too big and interactions become too complex to slide in and out of graphite’s layers. The cone and disc structures “offer curvature and spacing that welcome sodium and potassium ions without the need for chemical doping (the process of intentionally adding small amounts of specific atoms or molecules to change its properties) or other artificial modifications,” according to the study.

“This is one of the first clear demonstrations of sodium-ion intercalation in pure graphitic materials with such stability,” Atin Pramanik, first author of the study and a postdoctoral associate in Ajayan’s lab, said in the release. “It challenges the belief that pure graphite can’t work with sodium.”

In lab tests, the carbon cones and discs stored about 230 milliamp-hours of charge per gram (mAh/g) by using sodium ions. They still held 151 mAh/g even after 2,000 fast charging cycles. They also worked with potassium-ion batteries.

“We believe this discovery opens up a new design space for battery anodes,” Ajayan added in the release. “Instead of changing the chemistry, we’re changing the shape, and that’s proving to be just as interesting.”

---

This story originally appeared on EnergyCapitalHTX.com.

FAA demands investigation into SpaceX's out-of-control Starship flight

Out of this world

The Federal Aviation Administration is demanding an accident investigation into the out-of-control Starship flight by SpaceX on May 27.

Tuesday's test flight from Texas lasted longer than the previous two failed demos of the world's biggest and most powerful rocket, which ended in flames over the Atlantic. The latest spacecraft made it halfway around the world to the Indian Ocean, but not before going into a spin and breaking apart.

The FAA said Friday that no injuries or public damage were reported.

The first-stage booster — recycled from an earlier flight — also burst apart while descending over the Gulf of Mexico. But that was the result of deliberately extreme testing approved by the FAA in advance.

All wreckage from both sections of the 403-foot (123-meter) rocket came down within the designated hazard zones, according to the FAA.

The FAA will oversee SpaceX's investigation, which is required before another Starship can launch.

CEO Elon Musk said he wants to pick up the pace of Starship test flights, with the ultimate goal of launching them to Mars. NASA needs Starship as the means of landing astronauts on the moon in the next few years.

View All Listings