3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Taylor Anne Adams of Rice University, Kelly Adels Hess of CompuCycle, and Tatiana Fofanova of Koda Health. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a podcast with an innovation leader from Rice University, the CEO of a tech recycling company, and a startup founder with fresh funding.

Taylor Anne Adams, head of venture acceleration at Lilie

Taylor Anne Adams is working to support Rice University's most ambitious entrepreneurs. Photo courtesy of Lilie

Rice University can barely keep up with the interest of students in entrepreneurial classes and programming — even in the summer.

The university's Liu Idea Lab for Innovation and Entrepreneurship offers around 30 classes a year and over a dozen co-curricular programs — all focused on supporting student entrepreneurs.

"There is a huge desire for this across the campus," Taylor Anne Adams, head of venture acceleration at Lilie, says on the Houston Innovators Podcast. "Our class enrollment has just continued to skyrocket, and we've had to add on more classes and programs and that still seems to not be enough." Continue reading.

Kelly Hess, CEO of CompuCycle

Kelly Hess leads CompuCycle, a Houston-based company focused on electronics recycling. Courtesy of CompuCycle

An innovative Houston company focused on sustainable tech recycling has expanded.

CompuCycle describes its unique Plastics Recycling System as the first and only certified, single solution e-waste recycling business. The company's unique process can now break down discarded technology products into single polymers that can then be reused in the manufacturing process.

“Properly managing all components of electronics is a cornerstone of sustainability and environmental responsibility,” Kelly Adels Hess, CEO of CompuCycle, says in a news release. “Making single polymer plastics that original equipment manufacturers (OEMs) can reuse to produce new electronics or other products, while adhering to international recycling standards, is a gamechanger for domestic companies and those that need their plastics shipped globally.” Continue reading.

Tatiana Fofanova, co-founder and CEO of Koda Health

Tatiana Fofanova, co-founder and CEO of Koda, joined the Houston Innovators Podcast to discuss her company's growth. Image via LinkedIn

Koda Health achieved a successful oversubscription of additional seed round funding thanks to the participation of AARP, Memorial Hermann Health System, and the Texas Medical Center Venture Fund. The total amount raised was undisclosed, and the round was led by Austin-based Ecliptic Capital.

The tech platform improves planning for serious illness treatment and end-of-life care using a cloud-based advance care planning, or ACP, platform that pairs with in-house support. Essentially, it allows patients to do their planning ahead and make sure that their wishes are actually put into action. According to Koda Health, this results in an average of $9,500 saved per-patient, as well as improved health outcomes.

"If we’re looking at speed of market adoption, it’s clear that Koda Health is at the forefront of a crucial transformation in Advance Care Planning," says Tatiana Fofanova, PhD, CEO of Koda Health, in a press release. “In just a few years, we’ve built out a product that now serves well over 700,000 patients nationwide for industry giants like Cigna, Privia and Houston Methodist.” Continue reading.

CompuCycle reports that it's the only service provider in the country that can provide a recycling solution for both metals and plastics in-house. Courtesy of CompuCycle

Houston e-waste recycling business advances sustainability mission with new accreditation

seeing green

An innovative Houston company focused on sustainable tech recycling has expanded.

As of now, CompuCycle reports that it's the only service in the country that can provide a recycling solution for both metals and plastics in-house. The company has met the Environmental Protection Agency’s two accredited certification standards, e-Stewards and R2 certification requirements, per the release.

“We saw an opportunity to solve an industry challenge by creating the first domestic, sustainable, single-solution e-waste plastics program that reduces the amount of plastic negatively impacting the environment, while also making it advantageous for companies to recycle and reuse. It’s truly a win for everyone involved,” adds Clive Hess, president at CompuCycle.

CompuCycle, which has over a 20-year history, added recycling electronics to its toolkit in 2019. While CompuCycle has focused on responsible electronics disposal since Kelly's father-in-law, John Hess, founded the company in 1996, certain recent events have increased the need to recycle more efficiently.

"China is no longer accepting scrap, which is where a lot of materials would go after it was dismantled," Kelly told InnovationMap in 2019. "That's why we've created this solution to be able to responsibly handle it here in the U.S."

------

This article originally ran on EnergyCapital.

Houston-based CompuCycle has acquired a new shredder that can automatically sort and dismantle electronics. Courtesy of CompuCycle

Houston small business introduces state-of-the-art technology for electronics recycling

E-cycling

Currently, there are more than 135 million cell phones, 23 million televisions, and 31 million computers in landfills in the United States that don't have to be.

"Eighty percent of electronics are still landfilled in the United States," says Kelly Hess, CEO of CompuCycle, citing Consumer Take Back Coalition and EPA 2014 data. "We really want to advocate to change that number, because it's not necessary."

CompuCycle — a Houston company that has been around for over 20 years — has taken a big step toward that goal by adding an electronics shredder to its services. The shredder can dismantle 40,000 pounds a day of electronic material down to just about the finest it can get. It's the only of its kind in Houston — and one of only a few in Texas.

"It's a game changer," Kelly says. "When it comes to electronics recycling, if there's anything that can be sexy about it, this is sexy. It's as good as you can get."

As a R2 certified company, CompuCycle works with large corporations — local and worldwide — to safely wipe data from old electronics, refurbish them, and recycle what can't be refurbished. While most of the company's business is this B2B model, Harris County residents can drop off electronics to be disposed of responsibly free of charge.

While CompuCycle has focused on responsible electronics disposal since Kelly's father-in-law, John Hess, founded the company in 1996, certain recent events have increased the need to recycle more efficiently.

"China is no longer accepting scrap, which is where a lot of materials would go after it was dismantled," Kelly says. "That's why we've created this solution to be able to responsibly handle it here in the U.S."

The new Chinese law shifts the responsibility of electronics recycling back to the U.S., resulting in a rising need for more education and legislation surrounding recycling, says Clive Hess, executive vice president at CompuCycle and husband to Kelly.

"Texas has pretty weak electronic recycling laws — they do have some laws, and something is better than nothing," Clive says. "But, in a perfect world they wouldn't allow the landfilling of electronics."

At the end of the day, CompuCycle's new shredder is moving the needle on electronics recycling, but there's much more to be done, especially since recyclers still bear the brunt of the costs associated with recycling.

"We need to educate the manufacturers, the retail outlets, and the recyclers," Clive says. "We need to work together to provide recycling programs for people to take advantage of. There's a lot more work that needs to take place in order for recycling to be more effective."

CompuCycle's new shredder can dismantle 40,000 pounds of electronics materials a day. Courtesy of CompuCycle

Ad Placement 300x100

Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

$1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
$922 million for the University of Houston System
$167 million for Texas Southern University
$10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
Created the Lake Houston Dredging and Maintenance District
Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

---

A version of this article first appeared on EnergyCapitalHTX.com.

View All Listings

INNOVATIONMAP EMAILS ARE AWESOME