Here's what lean startup tips founders can learn from this Houston restaurateur and Rice University MBA

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Ope Amosu, a Rice University MBA grad, practiced a lot of lean startup techniques when starting his restaurant business, ChòpnBlọk. Photo via Instagram

It was one of those toasty, 95-degree evenings in late September in Houston, and we were clinking our craft cocktails to a full house at ChòpnBlọk's latest pop up concept – the fifth restaurant takeover in his series. I don't know what was hotter… outside, the vibe, or the spice in the ata rodo (scotch bonnet) maple syrup our plantain pancakes were lathered in. But one thing is for sure, as he prepares to open a brick and mortar location in 2020, Ope Amosu, a Rice University MBA graduate and the founder of ChòpnBlọk, is proving himself to be a mean, lean (startup) machine.

After getting his MBA from Rice Business in 2014, he began traveling extensively for work and was frustrated with his inability to easily access authentic West African cuisine in Houston and beyond. He was able to conveniently experience other cultures through successful restaurant concepts, but not his own. So in order to see if he had what it take to bring high quality, convenient West African inspired cuisine to Texas, he did what every MBA graduate dreams of: he rolled up his sleeves and secured a part-time job working the line at Chipotle.

Chipotle taught Ope the art of restaurant operations, and he made money learning it. Pulling together his lessons learned, he began building out his business plan. He identified a large West African population in Houston that was being under-served and was confident in his ability to address this market gap with his fast-casual concept. From his time working with various engineering groups, he knew that he needed to test his idea early so he could fail early and fail fast without breaking the bank.

This led to the inception of ChòpnBlọk. Ope knew acquiring a food truck would be too timely and too expensive, so he went a more creative, cost–effective route. He began hosting private dinners where his guests experienced a multi-course dining program rich with West African flavor.

Those full and happy guests unknowingly were participating in a fun focus group. He leveraged these dinners to collect data from each diner. What did they recommend he charge per meal? Did they like what they were eating? What was their current dining out behaviors? After hosting over ten smaller private dinners, he had collected valuable pieces of information that would inform his business plan including:

He had market data from over 200 diners.
He proved that there was an appetite for West African cuisine in Houston. His fears that the common stigmas about African culture would hinder his growth seemed unfounded.
He quickly optimized operational efficiency in feeding his guests.

Having validated customer demand, honed in on customer preferences, and demonstrated that the market opportunity he believed existed could be captured, all without taking on investors, it was time to take the next step. ChòpnBlọk began efforts to scale, finding a way to re-engage customers who were hungry for more.

This is how the pop-up experiences came to life. With his restaurant takeovers, Ope is able to serve well over 100 paying customers per dinner and gain all the operational know-how that goes along with such an affair. In a risk-free environment, he gets to test various creative concepts and fine-tune logistics…all with almost zero overhead and very minimal risk.

You can probably guess what is next. It should come as no surprise that ChòpnBlọk has been approached by funders and developers to launch a brick and mortar location for 2020. With hundreds of paying customers, a net promoter score staying high at 9/10, and an entrepreneur's tenacity like his, I have a feeling ChòpnBlọk will be coming for Chipotle in just a matter of time.

Want to learn more? Visit their website and follow them on Instagram.

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Caitlin Bolanos is the senior associate director at the Liu Idea Lab for Innovation & Entrepreneurship.

This article originally appeared on Liu Idea Lab for Innovation & Entrepreneurship's blog.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

New accelerator joins the Ion and more Houston innovation news to know

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New accelerator for AI startups to launch at Houston's Ion this spring

The new AI Native Dual-Use Sports, Health & Wellness Accelerator is expected to launch in March. Photo courtesy of the Ion

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform. The AI Native Dual-Use Sports, Health & Wellness Accelerator is scheduled to formally launch in March. Continue reading.

10+ can't-miss Houston business and innovation events in February

From recurring monthly favorites to the return of annual celebrations and summits, here's what not to miss in February. Photo courtesy the Ion.

February may be a short month, but its event calendar isn’t. From recurring monthly favorites to the return of annual celebrations and summits, here are the Houston business and innovation events not to miss — and how to register. Continue reading.

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