The University of Houston has teamed up with Chevron for a new fellowship program, which just announced its first class. Photo courtesy of UH.edu

The University of Houston has named eight graduate students to its first-ever cohort of UH-Chevron Energy Graduate Fellows.

The PhD and doctoral students will each receive a one-year $12,000 fellowship, along with mentoring from experts at UH and Chevron.

“The UH-Chevron Energy Fellowship program is an exciting opportunity for our graduate students to research the many critical areas that impact the energy industry, our communities and our global competitiveness,” Ramanan Krishnamoorti UH's Vice President for Energy and Innovation says in a statement.

“Today’s students not only recognize the importance of energy, but they are actively driving the push for affordable, reliable, sustainable and secure energy and making choices that clearly indicate that they are meaningfully contributing to the change,” he continues.

Their work focuses on energy-related research in fields ranging from public policy to geophysics and math. The fellowship is funded by Chevron.

“We love that Chevron is sponsoring this group of fellows because it’s a fantastic way for us to get involved with the students who are working on some of the biggest problems we’ll face in society,” Chevron Technology Ventures President Jim Gable adds.

The 2023 UH-Chevron Energy Graduate Fellows are:

The PhD and doctoral students will each receive a one-year $12,000 fellowship, along with mentoring from experts at UH and Chevron. Photo via UH.edu

Kripa Adhikari, a Ph.D. student in the Department of Civil and Environmental Engineering in the Cullen College of Engineering. Her work focuses on thermal regulation in enhanced geothermal systems. She currently works under the mentorship of Professor Kalyana Babu Nakshatrala and previously worked as a civil engineer with the Nepal Reconstruction Authority.

Aparajita Datta, a researcher at UH Energy and a Ph.D. candidate in the Department of Political Science. Her work focuses on the federal Low-Income Home Energy Assistance Program (LIHEAP), a redistributive welfare policy designed to help households pay their energy bills. She holds a bachelor’s degree in computer science and engineering from the University of Petroleum and Energy Studies in India, and master’s degrees in energy management and public policy from UH. She also recently worked on a paper for UH about transportation emissions.

Chirag Goel, a Ph.D. student in materials science and engineering at UH. His work focuses on using High Temperature Superconductors (HTS) to optimize manufacturing processes, which he says can help achieve carbon-free economies by 2050. The work has uses in renewable energy generation, electric power transmission and advanced scientific applications.

Meghana Idamakanti, a third-year Ph.D. student in the William A. Brookshire Department of Chemical and Biomolecular Engineering. Her work focuses on using electrically heated steam methane for cleaner hydrogen production. She received her bachelor’s degree in chemical engineering from Jawaharlal Nehru Technological University in India in 2020 and previously worked as a process engineering intern at Glochem Industries in India.

Erin Picton, an environmental engineering Ph.D. student in the Shaffer Lab at UH. Her work focuses on ways to increase the sustainability of lithium processing and reducing wasted water and energy. “I love the idea of taking waste and turning it into value,” she said in a statement. She has previously worked in collaboration with MIT and Greentown Labs, as chief sustainability officer of a Houston-based desalination startup; and as a visiting graduate researcher at Argonne National Lab and at INSA in Lyon, France.

Mohamad Sarhan, a Ph.D. student and a teaching assistant in the Department of Petroleum Engineering. His work focuses on seasonal hydrogen storage and the stability of storage candidates during hydrogen cycling. He holds a bachelor’s degree and a master’s degree in petroleum engineering from Cairo University

Swapnil Sharma, a Ph.D. student in the William A. Brookshire Department of Chemical and Biomolecular Engineering. His work has been funded by the Department of Energy and focuses on thermal modeling of large-scale liquid hydrogen storage tanks. He works with Professor Vemuri Balakotaiah. He holds bachelor's and master’s degrees in chemical engineering from the Indian Institute of Technology (IIT). He also developed one of the world’s highest fiber-count optical fiber cables while working in India and founded CovRelief, which helped millions of Indians find resources about hospital beds, oxygen suppliers and more during the pandemic.

Larkin Spires, who's working on her doctoral research in the Department of Earth and Atmospheric Sciences in the College of Natural Sciences and Mathematics. Her work focuses on a semi-empirical Brown and Korringa model for fluid substitution and the ties between geophysics and mathematics. She works under Professor John Castagna and holds a bachelor’s degree in math from Louisiana State University and a master’s degree in geophysics from UH.

Earlier this month Evolve Houston also announced its first-ever cohort of 13 microgrant recipients, whose work aims to make EVs and charging infrastructure more accessible in some of the city's more underserved neighborhoods.

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This article originally ran on EnergyCapital.

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New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

Microsoft partners with Rice University's OpenStax on AI teaching tool

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Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”