A Houston entrepreneur is creating a fun and educational platform for children that helps to preserve their heritage. Photo by Kelly Sikkema/Unsplash

Theoharis Dimarhos grew up in a family determined to follow tradition. As a child, his mother serenaded him with old Greek folk songs he still remembers, and his parents made speaking Greek a rule of the house. Dimarhos lived the immigrant family experience, and now he's developed a modern way to preserve pass down culture to the masses.

"My parents came from Greece in 1981, and in typical fashion, they didn't have much and didn't speak the language at all," says Dimarhos, who was born in Cleveland, Ohio. Living the first-generation American experience, he watched his parents work tirelessly to provide for the family and maintain their Greek culture in America.

Dimarhos did get his own immigrant story when his parents decided to move back to Greece when he was 7. After assimilating to Greece, he traveled back to the United States for college, where he learned to readjust once more.

"I kind of got that immigrant experience a couple of times," he says.

While Dimarhos grew up surrounded by his own heritage, he began to realize that "our native cultures were destined to fade if there wasn't a more modern way for children and our little siblings to learn more about their roots."

When talking with his friends from other countries outside of Greece, a general consensus grew: without modern learning, family heritage would slip away.

Enter: Ellis, an app that helps children connect to their culture. The app includes Greek songs, fables, mythology, history, and language.

Named after Ellis Island, a gateway into the United States for so many immigrants in history, Ellis nurtures Greek tradition in a way that caters to children through technology.

"I've always seen [Ellis Island] as a monument of courage to chase your dreams. . .people came and built this country, but also never forgot where they came from."

Interactive technology is becoming a large part of early childhood education, especially during COVID-19, as more families are at-home with children learning virtually. Children are the targets of over 80 percent of the top-selling paid apps in the education category of the iTunes store, according to a published analysis by Carly Shuler in 2012.

Dimarhos and his wife are deeply tied to their Greek heritage, and hope to pass that history and appreciation to their own children once they start a family.

"We wanted to make sure that there was a 21st century way for us and for our children to learn that goes beyond books," he says. "Something that's a little more immersive and fun — fun is very important — and educational."

Ellis is currently being beta tested with a group of 200 active users within the Greek community. The app, which targets ages 0-8, rolls out weekly content to parents.

"I'm receiving texts from friends who are parents begging me to put more content out because they need something to keep their children occupied," says Dimarhos. "Not only are regular schools closed, but cultural schools that are offered by the community are also closed and struggling to open back up."

Time spent on the app can be as short as five minutes and stretch into hours of learning time.

"The goal is always for children to pick up little phrases and words each time they listen," explains Dimarhos.

The stories and songs are all audio-based, tying into activities like waking up, eating breakfast, and bathtime.

"There's something magical about tying in an audio story or song with everyday tasks for kids," says Dimarhos.

Dimarhos parents see the app as "the next step of passing down the torch of our culture," he says.

"They tried to do it with the tools that they had for myself and my sister. . .We're trying to do the exact same thing that they did and their parents did, just with the tools that technology offers us," he says.

Dimarhos, who previously worked in economic development in Austin, had his first experience with startups when his former boss gave him a chance to work with his international accelerator for startups.

"I got my opening into the tech world through the international accelerator and seeing amazing immigrant founders create jobs and strive to do great things in America," he shares.

"Quite honestly, a startup that celebrates different cultures couldn't have a better home than in Houston," he says, noting the massive immigrant population and variety of cultures in the city.

In Dimarhos' own life, he's come across immigrants as well as first and second generation Americans who wish to preserve their own cultures.

"They've wished there was a more modern way to have access to those resources," he explains.

In the future, Dimarhos intends to quickly broaden the app to "launch in every immigrant community in the United States and around the world."

Connecting to cultural roots is something Dimarhos feels is "sacred" to immigrant families.

"It's something that you have the obligation from your parents as they give you everything for you to succeed in life. You kind of carry that obligation to carry that torch and pass it on to your children and their children," he explains.

"We grow up with that and the vision and the mission is just to create something that makes that a little bit easier to keep our cultures alive. I honestly think it's part of what makes this country great," he says.

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Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.