3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Tim Crain of Intuitive Machines, Chelsea Williams of Northwestern Mutual, and Nicolaus Radford of Nauticus Robotics. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space tech to robotics — recently making headlines in Houston innovation.

Tim Crain, co-founder and CTO of Intuitive Machines

Tim Crain joins the Houston Innovators Podcast. Photo via intuitivemachines.com

It might surprise many to learn that publicly traded, NASA-backed Intuitive Machines, which has emerged as a commercial leader within lunar access technology development, had several pivots before finding its niche within space innovation.

In fact, as Co-Founder and CTO Tim Crain explains on this week's episode of the Houston Innovators Podcast, the company was founded as a space-focused think tank. Crain, along with his co-founders CEO Steve Altemus and Chairman Kamal Ghaffarian, came together in 2013 to start Intuitive Machines, which recently moved into a $40 million headquarters in the Houston Spaceport.

"At the time, our thought was, 'let's take the best of human space flight engineering processes, disciplines, and know how, and look at how we might commercially deploy that for biomedical, energy, big data, and aerospace,'" Crain says on the show. "We wanted to look at how we use great engineering for some of the hard problems outside of NASA's aerospace sphere." Read more.

Chelsea Williams, financial adviser at Northwestern Mutual

Houston-based financial adviser Chelsea Williams helps clients overcome their unique generational financial uncertainties by equipping them with tips and resources to get them on the path to financial wellness. Photo courtesy

In a guest column for InnovationMap, Chelsea Williams, financial adviser at Northwestern Mutual, shared tips on overcoming financial uncertainty across different generations.

"While the types of financial stressors might vary across generations and cities, the most important step to managing financial uncertainty is initiating a conversation with an adviser," she writes in her column. "Just like going to the doctor regularly, routine financial check-ups are incredibly important to catch financial headaches early on and stay ahead of long-term financial health." Read more.

Nicolaus Radford, founder and CEO of Nauticus Robotics

Houston-based Nauticus Robotics founder, Nicolaus Radford, celebrated an acquisition for his company. Image via LinkedIn

A Houston company that harnesses the power of robotics hardware and programing for underwater use has made an acquisition.

Nauticus Robotics Inc. (NASDAQ: KITT) announced it has acquired 3D at Depth Inc., a Colorado-based company with a subsea light detection and range, LiDAR, technology for inspection and data services. The deal closed for approximately $34 million in stock, before certain purchase price adjustments and the assumption of debt, per the news release.

“The future of subsea services lies in autonomy, data gathering, and analytics,” Nicolaus Radford, Nauticus’ founder and CEO, says in the release. “LiDAR has long since been core to terrestrial autonomy and by adding 3D’s capabilities to the Nauticus Fleet, we enhance autonomous vehicles in the offshore market. This acquisition increases the value of Nauticus’ fleet services and positions the Company to capitalize on data acquisition and analytics for subsea operations.” Read more.

Houstonians in particular expressed more stress than other communities in terms of household finances and physical and mental health. Photo via Getty Images

Houston expert on tips on overcoming financial uncertainty across different generations

guest column

Whether you’re a millennial or baby boomer, financial uncertainty is not limited by age, with new data from Northwestern Mutual’s 2023 Planning & Progress Study revealing that most Americans are losing sleep at night because of it. Houstonians in particular expressed more stress than other communities in terms of household finances and physical and mental health, according to a recent survey.

While the types of financial stressors might vary across generations and cities, the most important step to managing financial uncertainty is initiating a conversation with an adviser. Just like going to the doctor regularly, routine financial check-ups are incredibly important to catch financial headaches early on and stay ahead of long-term financial health.

As a Houston-based financial adviser, I help my clients overcome their unique generational financial uncertainties by equipping them with tips and resources to get them on the path to financial wellness.

Understanding where financial uncertainty comes from generationally

  • Gen Z: Studies have shown that even while Gen Z is the most confident that they’ll be prepared for retirement when the time comes, they still struggle with feelings of uncertainty on how to achieve their specific financial goals. In my experience, I have found that uncertainty among this age group often stems from a lack of financial literacy surrounding their finances. A recent financial literacy study revealed that Gen Z respondents averaged the lowest at 43 percent in answering finance-related questions correctly.
  • Millennials: Millennials equally suffer from feelings of anxiety about money, with 54 percent of millennial respondents in the P&P study indicating that financial anxiety causes them to feel depressed compared to just 20 percent of baby boomers. Millennials have lived through a pandemic, The Great Recession and slow economic growth, making their mental health and financial wellness a top priority.
  • Gen X: Even while financial uncertainty typically starts to recede later in life at this age, Gen X is facing a turning point as they get closer and closer to retirement. Studies have shown that most Americans believe they will need about $1.27 million to retire comfortably and yet, I see many individuals only recognizing the importance of retirement planning between the ages of 40 and 50. With Gen X holding about six times more debt than their parents did at that age, it’s important for this age group to consider some proactive debt and retirement strategies.
  • Baby boomers: This group has the lowest amount of financial uncertainty, but that doesn’t mean it is nonexistent. I hear a lot of baby boomers state that they wish they had started investing sooner or they wish they had conversations about their finances sooner. As such, this group is typically the most concerned about managing their existing assets and living comfortably for the rest of their lives.

Overcoming financial uncertainty

  • Increase financial literacy: Both millennials and Gen Z grew up in the digital age and expect their financial experiences to be reflective of that. For employers with Gen Z employees, working with a Northwestern Mutual financial adviser on resources to increase financial literacy can be a helpful first step. This could include on-demand webinars, digital toolkits and interactive online portals to access and view their finances.
  • Ensure every dollar has a job: Across all generations, it’s important to ensure no dollar is wasted. In other words, understanding how much of your income should be allocated toward expenses, retirement, savings, etc. is crucial. I typically recommend a budgeting rule that no more than half of an individual’s income goes toward expenses.
  • Initiate financial planning discussions early on: While it may seem daunting, results from the P&P study show that an average of 76 percent of individuals who work with a financial adviser have an overall boost to confidence. With Gen Z often heavily relying on family members for money management, it is important that family members from older generations encourage them to start saving or to consult with a financial adviser at a young age.
  • Take proactive steps toward your finances: No matter what age you are, there are always active steps you can be taking with your finances. Consider increasing the contribution amount to your 401(k) savings plan or working with a financial adviser to diversify your existing investments – or talk to your financial adviser about refinancing opportunities or debt strategies that tackle higher interest loans you may have.

Whether you’re in your 20s or your 50s, financial advisers are uniquely prepared to help you at any stage of your life – and overcome whatever uncertainties you may be facing.


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Chelsea Williams is a financial adviser at Northwestern Mutual. She's based in Houston and has clients across the country.

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

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A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.

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