These are Houston's 4 best high schools in 2021, says recent report

REPORT CARD

Here's what Houston schools have been lauded for training the city's future leaders. Photo by skynesher/Getty Images

t's report card time, and four Houston high schools have made the grade, earning top 100 spots in this year's prestigious U.S. News & World Report rankings of the Best U.S. High Schools. One even merited a special distinction.

Houston's Carnegie Vanguard High School ranked highest on the list at No. 42. The school is ranked fifth within Texas. The Advanced Placement coursework participation rate there is 100 percent; total minority enrollment is 77 percent, and 31 percent of students are economically disadvantaged.

Following close behind is the prestigious DeBakey High School for Health Professions at No. 46 overall. The renowned medical prep school boasts an AP participation rate of 98 percent, total minority enrollment is 88 percent, and 44 percent of students are economically disadvantaged.

Farther down the list is Challenge Early College High School, at No. 89 overall. The AP participation rate here is 100 percent, total minority enrollment is 92 percent, and 76 percent of students are economically disadvantaged.

At No. 97 overall is Young Women's College Prep Academy. The AP participation rate here is 100 percent. The total minority enrollment is 97 percent, and nearly all students — some 96 percent — are economically disadvantaged.

The 2021 edition is U.S. News' most comprehensive survey yet, with the consumer advice outlet evaluating more than 17,800 public high schools on how well they serve all of their students, regardless of economic or ethnic background.

To determine rankings, they focus on six factors: college readiness, reading and math proficiency, reading and math performance, underserved student performance, college curriculum breadth, and graduation rates. College readiness specifically measures participation and performance on Advanced Placement and International Baccalaureate exams.

Notably, the data used in this edition is from the 2018-2019 academic school year, so it was not affected by the COVID-19 pandemic.

"Families can use the Best High Schools rankings to see how schools compare at the national, state and local level on factors like graduation rates and college readiness," said Anita Narayan, managing editor of Education at U.S. News, in a statement. "The rankings also provide insight into academic performance among underserved groups showing how well schools are supporting these students."

Eight more Texas schools also appear on the national top 100 list:

  • No. 13, School for the Talented and Gifted, Dallas
  • No. 15, Irma Lerma Rangel Young Women's Leadership School, Dallas
  • No. 39, The Science and Engineering Magnet School, Dallas
  • No. 41, Liberal Arts and Science Academy, Austin
  • No. 42, Carnegie Vanguard High School, Houston
  • No. 46, DeBakey High School for Health Professions, Houston
  • No. 59, Judge Barefoot Sanders Law Magnet, Dallas
  • No. 68, IDEA Frontier College Preparatory, Brownsville
  • No. 89, Challenge Early College High School, Houston
  • No. 96, Health Careers High School, San Antonio
  • No. 97, Young Women's College Prep Academy, Houston
  • No. 98, Ann Richards School for Young Women Leaders, Austin

Just over the top 100 threshold is Grand Prairie Fine Arts Academy, coming in at No. 101.

Texas had 1,524 schools ranked this year, of which 42 placed in the top 5 percent, 79 in the top 10 percent, and 157 in the top 25 percent nationally.

Statewide, the top 10 highest ranking schools were:

  1. The School for the Talented and Gifted (TAG), Dallas
  2. Irma Lerma Rangel Young Women's Leadership School, Dallas
  3. Science and Engineering Magnet School (SEM), Dallas
  4. Liberal Arts and Science Academy (LASA), Austin
  5. Carnegie Vanguard High School, Houston
  6. DeBakey High School for Health Professions, Houston
  7. Judge Barefoot Sanders Law Magnet, Dallas
  8. IDEA Frontier College Preparatory, Brownsville
  9. Challenge Early College High School, Houston
  10. Health Careers High School, San Antonio

So, which school throughout the country ranks as this year's valedictorian? Thomas Jefferson High School for Science and Technology in Alexandria, Virginia was deemed the best in the country, as well as among magnet schools. Read the full report and search for schools here.

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This article originally ran on CultureMap.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”
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