Memorial Park, which is currently undergoing a master plan renovation, and other Houston parks can be a great opportunity for introducing urban conservation inside the city limits. Rendering courtesy of Nelson Byrd Woltz

The Houston toad is a species that was discovered in Harris County in the 1950s. It has a very distinct, loud call that reverberates at quite a high pitch. But the Houston toad's call hasn't been heard in the city of Houston for almost 50 years. The species is locally extinct and critically endangered elsewhere. In fact, it's the most endangered amphibian in North America, says Cassidy Brown Johnson, a Rice University lecturer and president of the Coastal Prairie Partnership.

"When we think about extinction, we think of the dodo bird or the woolly mammoth," Johnson says. "But extinction is happening right underneath our noses."

The Houston Zoo has a breeding facility for Houston toad, but other than that, it's extremely unlikely that the Houston toad will ever reside naturally in its namesake city.

"We have modified the environment so heavily, that it'd be a bit of a dicey thing to do [to reintroduce the species] because there are so few of them, it's better to focus on an environment where it's still OK for them," Johnson says. The largest population of the Houston toad is actually in Bastrop, however due to the Bastrop fires in 2011, the species is only just recently back to a good place even there.

Johnson is giving a free lecture in April at Rice regarding extinction, where she'll bring her Astros-named Houston toads, Springer and Julia Morales, as her teacher aids.

Changing tides in conservation
As cities like Houston continue to be developed, scientists and researchers are challenged with finding new ways to effect conservation. Johnson says within the industry, there's been a shift in thinking when it comes to preserving nature.

"There's a new burgeoning movement in conservation called urban conservation," she says. "For a long time, if you talked to the traditional conservationists, the idea of conservation is to protect big spaces — the national and state park systems are the perfect example."

But large parks are expensive and a huge undertaking. It's still the strongest form of conservation, but introducing conservation efforts in a city — perhaps in some of Houston's parks, like Memorial Park or Hermann Park — helps not only the species of animals involved, but also educates the local population and forms a connection with residents.

"That has a twofold kind of benefit," Johnson says. "It protects the greenspace so species to live with us, and then also it makes the connection to this place we try to protect."

Of course, this type of effort is new, and there's not a lot of data to show how this would affect the ecosystem and its species, from the migratory and genetic diversity standpoints. Despite the lack of data, Johnson says this type of effort needs to happen.

"We're going to continue to manipulate the world, and maybe if we started thinking about this now, that we can get to a point were we understand enough were we can make these some sort of functioning ecosystem," she says.

Part of the shift in thinking about these ecosystems has to do with new ways of tracking species and understanding their environments.

"Technology is helping us ask a lot of these questions," Johnson says. "Ecology is surprisingly complicated. There's so many variables. ... I think technology and our advance with computing is definitely going to help us understand it."

Using preservation to solve flooding
The educational component is also very important to conservation, and Johnson is making strides on campus with her class. Last year, her department and her class introduced a pocket prairie right on the Rice campus.

Before it was the fourth largest city in America, Houston was a prairie. That type of ecosystem — thick with prairie grass — is very absorbing when it comes to rain water.

"It's really surprising to people that the trees and all this lushness is actually all artificial," Johnson says. "We know that this ecosystem evolved with the cyclical flooding events that happened here."

This movement to bring back Houston's ancient ecosystem is a new focus on a few prairie conservationist groups — and even the Harris County Flood Control. This has been going on for a while, but recent flooding events have opened the eyes of people now looking for reliable solutions to flooding problems.

"After Hurricane Harvey, people started realizing that this might be one of the solutions we could actually investigate and see if it can help us," Johnson says. "A green space is going to absorb way more water than a parking lot."

Of course, there are other flood solutions being discussed — some even incorporating tech or even a tube system underground.

"Historically, there has been some budding of heads between the environment and technology, but I really think moving forward, those two fields have to work together. We need to use technology to save the environment," Johnson says. "I think Houston is one of the places where that conversation is starting to happen."

Missing the toads

Courtesy of Cassidy Brown Johnson

The Houston toad has been locally extinct since the 1970s.

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.