Many Houstonians are unemployed, laid off, or furloughed amid the pandemic. Others are literally burned out and ready for a life-altering career change. This expert has advice for both. Photo via Pexels

I've had so many pivots in my professional career; moving across the country, internal promotions, leaving a corporate job to launch my own company, and repositioning myself and my brand in new markets. But I'm one of those people who enjoy lots of change, and as I've continued in my career journey, I've found that those sentiments are not shared by many.

Making a career transition can not only be stressful for a majority of professionals but can paralyze people from making decisions that carry their livelihood alongside them. This is one reason I am fueled to help professionals, to be a support system for these complexities and helping them make decisions based on facts and strengths, not on fear.

As a career coach, it's my job to find a way to piece together years of experience for professionals in order to tell a story of growth, change, and transferable potential to sway key decision-makers for employment and economic opportunity.

Over the past several years, I've seen many trends in client challenges, storytelling similarities and developed a knack for helping people with complex stories make a successful career or entrepreneurial leap.

A new approach to career transitions

But then at the end of 2019, COVID-19 crept across Asia, slowly derailing markets, leading me to shift my focus to supporting my European clients as they began their lockdowns.

Job offers were being taken off the table, hiring freezes were put in place and travel required a two-week quarantine at either end. The fear in each of my clients' voices was palpable, and my resolve needed to be strong. I needed to stay steady, calm, and think more strategically than ever before to help them navigate this unchartered territory.

Within two months, the United States had been infiltrated by the virus, and the layoffs and furloughs began piling up. Now I was working across nations and states going through different phases of impact and needing to understand how to support these entrepreneurs and professionals in navigating through this.

Navigating the nuances of career change

What I realized is that I already had these answers. Navigating complexity has been my place of zen and working with intelligent, hungry individuals like yourselves continued to fuel my ability to innovate strategy and make a significant impact on career transitions.

I began to divide clients into priorities: furloughed and need work, laid off, overworked and need an exit, career epiphany, and entrepreneurs needing to reevaluate their business models.

If you were furloughed, there was a sense of hope, anxious to return to the workforce, and leaving bitterness for many when that call never came. In the state of Texas, 2.5 million professionals have lost their jobs, and only 1.8 million returned to work in 2021 to date.

In Houston, unemployment rates have maintained a high rate of about 8 percent in recent months. At the peak of COVID-19, the unemployment rates spiked significantly to more than 14 percent which translates to a large number of qualified people out of work.

Laid off and evaluating next steps

For those who were laid off, we had to evaluate financials. Was this a three-month endeavor or an ASAP, "my electricity will be shut off in two weeks if I don't find a job" scenario?

That dictated how we approached it. For the longer timeframe, we looked at roles carefully and targeted the best outcomes, tailored branding documents, and profiles and were highly intentional about applications.

In the second scenario, we made mandatory updates to branding and started the rapid apply approach to line up interviews quickly — even if it was going to be a short stint or a less than a glorious long-term option.

Overworked and anxious

Overworked and anxious to leave their jobs, this group had different desperation in their voice. They had previously enjoyed what they did, had an ambivalent outlook toward their employer, and thought things were 'going well.' This all changed when their support staff was sent home on furlough and those hours and that workload was enveloped by their department. These professionals felt blindsided.

How could things go from 'all is well' to 'get me out of here NOW!' in only a few short weeks? The mental, emotional, and physical stresses were and continue to be a leading factor in the rise in depression across the nation from 20 to 25 percent to 40 to 50 percent.

For this group of professionals, we focused on the role they had before the pandemic hit and those areas of fulfillment. We also focused on boundary setting to help support a move to a company where boundaries would need to be upheld to promote a healthier life balance.

Career epiphany clients

Next were my career epiphany clients. These professionals were awoken from the monotony that was once their career. Working from home, having different priorities, and learning to juggle many hats afforded new perspectives. This also meant that these professionals were no longer fulfilled in the direction of their careers, and were prepared to start anew.

This opened up an entire world of possibilities.

Unlike the career changes who had immediacy and trauma associated with their move, these epiphany clients were optimistic and strangely calm amidst the chaos and weight of this decision. Their priorities were no longer focused on one area but encompassed a much more holistic viewpoint.

And so, having the calm on our side, we would spend time working through their work attributes, close values, and defining their innate drivers in life. This work allowed us to choose roles that spoke to them.

Entrepreneurs

In the last group were my entrepreneurs. These business owners were looking at a brand new market and not knowing how to evolve their business model to fit the needs and budgets of their consumers. So many were filled with doubt on how they could ask for more money, or not have to increase their working hours to make the math work.

Our work felt like an enormous puzzle, putting all the right colors together first, then seeking out the corners and edges, until we could work toward the middle and most ambiguous pieces.

Together we redefined their clients (were they the same? Did they have the same needs now?) and how to best serve them. This required them to get out of their tried and true practices, as needs and budgets have also changed and evolved for their customers and clients. So we reverse-engineered into new pricing and service offerings that would provide immense value in a time when people needed it the most.

Each set of variables were unique, but the mindset and fears were so aligned with one another within each of these groups that I could provide streamlined tools that I knew would work to move the dial in their progression and overall success.

Innovative approach to career transitions

Utilizing resources that I already had, meant I just needed to find innovation in my approach. How was I to get professionals and entrepreneurs to learn and apply at rapid speed? How would I get through to them during this stressful time?

The approach was to give more actionable tools for them to leave each call with purpose and a sense of adventure ahead. I utilized a goal-setting sheet to identify priorities and lead from their reality, rather than standard best practices.

We focused on 4 key areas:

  1. Financials
  2. Growth
  3. Roles
  4. Timeline.

I realized that the biggest fears were in the unknown. So if we could start at a basic framework of knowing what they needed in order to pay bills and not disrupt life more, we could then focus on what was in their ideal, their wants, their bigger goals.

But I found that almost everyone trying to envision more money, or growth in roles during a global pandemic, didn't know how to focus on the future if they didn't know what needed to happen now, in the current state.

Everyone's reality was different, yet the momentum and freedom created by writing down their most vulnerable, essential needs, created a release in their energy and made conversation fill with hope. Having created a tangible plan of action had more impact than ever before. I took this momentum and challenged clients to do their homework, speak to their partners, their families.

With every group of transitioning professionals, this worked. My analogies and anecdotes changed and evolved as the year progressed, but this new starting point was the cornerstone to build confidence and momentum quickly.

Building a new path

As we start to see Texas opening up its businesses and mask requirements starting to shift, we will continue to see people in flux.

Overcoming storms, a pandemic, depression rates increasing, and an influx of new residents, the state will continue to find resilience. But professionals need to understand that before letting fear set in, there are steps you can take to release that pressure and build a new path, a new career, and a new story.

Understand and embrace your reality, write it down, uncover what is leading the fear, then take the first step to eliminate it.

Making a transition takes effort, but understanding your options based on your needs, and then your wants, will help create the movement you need to take that next step and keep moving in the right direction.

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Briar Dougherty, CEO and president of Career Organic, an Atlanta-based career coaching company.

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Eli Lilly scoops up Houston biotech startup in $300 million deal

big pharma deal

Pharmaceutical giant Eli Lilly has acquired Houston biotech startup CrossBridge Bio, which develops antibody-drug conjugates for cancer, in a deal worth up to $300 million. The deal was celebrated by TMC Venture Fund and the University of Texas Health Science Center at Houston last week.

CrossBridge, founded in 2023, is developing ADCs based on research by Kyoji Tsuchikama and Zhiqiang An, both of UT Health Houston. Tsuchikama is an associate professor of medicinal chemistry and a globally recognized ADC pioneer, and An is a professor of molecular science and vice president of drug discovery.

Antibody-drug conjugates (ADCs) are a potent combination of targeted therapy and chemotherapy that kills cancer cells while saving healthy tissue.

Clinical trials for CrossBridge’s primary ADC candidate, CBB-120, are expected to start this year, pending approval from the U.S. Food and Drug Administration (FDA).

“I’m proud of how well our team has executed and advanced our platform in such a short time since the company’s founding,” Michael Torres, co-founder and CEO of CrossBridge, said in a news release. “By becoming a part of Lilly, a leader in patient-focused therapeutic development, we are well-positioned to further accelerate the clinical potential of this approach.”

Under the Lilly deal, CrossBridge shareholders were expected to receive an upfront payment along with a follow-up payment based on the achievement of certain milestones.

In 2024, CrossBridge closed a $10 million seed round. Among the investors in CrossBridge are the Texas Medical Center Venture Fund, CE-Ventures, Alexandria Venture Investments, Portal Innovations, Linden Lake Labs, and the Cancer Prevention and Research Institute of Texas (CPRIT). It was formed in TMC Innovation’s Accelerator for Cancer Therapeutics program."Built within the TMC ecosystem, CrossBridge Bio grew with the support, funding, and resources that helped shape its trajectory. TMC led the company's early financing and watched it evolve from its earliest days to its acquisition by Eli Lilly," William McKeon, president and CEO of the Texas Medical Center, shared in a LinkedIn post. "[This is a] strong reminder that breakthrough science and the right early backing can change what’s possible."

7 Houston neighbors named to U.S. News' best places to live in 2026

Living Well

Several Houston suburbs have been crowned the best places to live in the U.S. for 2026, according to U.S. News & World Report. Sugar Land is the highest-ranked city in the Houston metro, and it ranks as the 10th best place to live in the country.

The annual list of Best Places to Live in the U.S. is designed to help readers make the most informed decisions when choosing where to settle down, using data from sources such as the U.S. Census Bureau, Department of Commerce, the Federal Reserve and the Bureau for Economic Analysis, as well as state and local sources.

For the 2026-2027 rankings, U.S. News featured 250 U.S. cities and ranked them across four livability indexes — quality of life, value, desirability, and job market — weighted by importance based on survey results of approximately 500 Americans. The rankings were also broken down state-by-state, as well as the best big, medium, and small cities overall.

Sugar Land is the No. 4 best places to live in Texas, and it soared into the No. 10 spot overall in the nation after ranking 16th last year. Sugar Land also ranks as the fourth-best mid-sized city to live in America for 2026-2027.

According to U.S. News, Sugar Land's median household income is far higher than the national average. Residents make $140,511 per year, while the average American household income is only $83,181.

Additionally, the $431,815 median home value in Sugar Land is also far greater than the $359,870 national average.

After ranking in the top 10 in the 2025 report, League City and Pearland now both rank outside the national top 10 for 2026. League City slipped from No. 6 to No. 13 this year, while Pearland dropped from No. 3 nationwide to No. 16.

These three Houston suburbs also boast highly desirable job markets for potential newcomers or current residents that want to start or change their career.

Houston proper, however, remains outside of the top 250 and is the 327th best place to live in the U.S., and it's the 60th best place to live in Texas.

Other cities in the greater Houston area that ranked among the top 100 include:

  • No. 28 – The Woodlands
  • No. 38 – Katy
  • No. 61 – Missouri City
  • No. 82 – Spring

The Lone Star State had a "strong showing" in the overall top 10 thanks to its "high affordability scores," a release said. Besides Sugar Land, three more popular Texas suburbs made the cut: Leander (No. 8) outside Austin and Dallas-Fort Worth suburbs Flower Mound (No. 3) and Frisco (No. 9).

"As prices of everyday goods continue to rise, consumers are considering affordability as a top priority when choosing a place to live," said U.S. News consumer lending analyst Erika Giovanetti. "While U.S. News’ consumer survey indicated that quality of life and affordability were close in importance, cost-of-living concerns resulted in many Americans putting what they can afford above their aspirations."

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This article originally appeared on CultureMap.com.

7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.