Exclusive: Canadian energy software company plans to grow local team and open Houston office

new to Hou

A Canadian software company is expanding its presence in Houston to meet the needs of its clients. Photo via Getty Images

One of the biggest obstacles heavy industry tech startups face — especially in oil and gas — is getting that first big customer, says Vicki Knott, co-founder and CEO of Crux OCM.

"Our biggest challenge is nobody wants to be first in energy," she tells InnovationMap.

But Crux OCM, based in Calgary, overcame that challenge and currently counts Houston-based Phillips 66 among its clients. The two companies announced a pilot program for Crux OCM's pipeBOT technology earlier this year.

Crux OCM's technology focuses on automating the control room operations — something that, like most automation software, increases revenue and reduces errors. The company, which was founded in 2017, also allows its clients consistency and reliability with its software.

"Even though the pumps and the equipment are automated, control room operators are still executing procedures, checklist, and rules of thumb on their own via screens," Knott says. "If you think of pilots and planes have autopilot software, why don't our control room operators? That's really the problem we set out to tackle."

Vicki Knott is co-founder and CEO of Crux OCM. Photo courtesy

Automation is certainly a growing opportunity for energy companies — especially in light of the pandemic that forced remote work and less on-site personnel across industries. Knott says just over a year ago, Crux OCM saw increased interest.

"We had a couple customers who had their capital budget cut when the pandemic hit and when oil went negative, and we had a couple customers who said they were doubling down on software like this," Knott explains.

The company has raised $3 million in venture funding, backed by Root Ventures, Angular Ventures, and Golden Ventures. Knott says another funding round is on the horizon as is growth for its Houston presence.

Crux OCM currently has three full-time Houston employees and is looking to grow that team in the next six months. Specifically, the local team will focus on sales, as well as product development, as the company's head of sales and senior product manager are both based here. As the local clientbase grows, Knott says they will also need to hire deployment engineers as well.

A new office to support this growing team is also in the works. Knott says she's looking for space in North Houston, and, depending on how comfortable people are returning to offices and meetings, it could open as early as later this year.

Calgary and Houston have a lot in common, Knott says, and she sees a very natural connection to the two regions. Knott plans to work six months of the year in Houston with the local office.

"A lot of the companies that head offices in Houston, they have head offices in Calgary," she says. "If a startup in Houston is getting traction, I think there's a natural movement to start in the Calgary market and vice versa."

Catch up on space news — from new partnerships at Rice University and the latest snub for the Space City. Photo via NASA.gov

Space City News: Houston passed over for military HQ, Rice forms new partnerships

aerospace updates

It's been a busy few days for space news, and in Houston — the Space City — it's all relevant to the continued conversation of technology and innovation.

With so much going on — from Houston being passed over for the Space Command's headquarters and Rice receiving $1.4 million in federal funds for a new hub — here's what you may have missed in space news.

The Ion awarded $1.4M to launch Aerospace Innovation Hub

The Ion will be home to the Aerospace Innovation Hub, thanks to a federal grant. Courtesy of Rice University

Through a partnership with NASA's Johnson Space Center and DivInc, The Ion has been awarded $1.4 million in federal funding to create its Aerospace Innovation Hub. The ASCI-Hub will support and develop regional minority business enterprises addressing aerospace-related challenges.

"Landing this award is another win for the region that leverages the unique strengths of the crewed space program at NASA JSC," says Jan E. Odegard, interim executive director of the Ion, says in a news release. "As Houston was critical to landing men on the moon in the late-'60s, the Ion's Aerospace Innovation Hub will be key not only to advancing the future of spaceflight, including the mission to Mars in the future, but also to tackling challenges facing our everyday lives here on Earth."

The hub will provide NASA's expertise and resources across robotics, medicine, health support systems, additive manufacturing, and more — as well as community events, education and training, and an accelerator program.

"We're eager to partner with the MDBA, Rice University and the Ion to help develop and grow minority entrepreneurs and accelerate innovative and tech-forward solutions in Houston," says Vanessa Wyche, deputy director of the JSC, in the release. "This partnership builds toward NASA's goals to enhance scientific and technological knowledge to benefit all of humankind and catalyze economic growth, as we propel commercialization of space and extend our presence in the solar system."

Opening in 2021, the Ion announced $1.5 million in grant funds in September. Those funds are going toward accelerators, which will collaborate with the Aerospace Innovation Hub.

"While we have taken many small — and valuable — steps over the past few years, this is one giant leap forward for our efforts to promote sustainable inclusion in Houston's entrepreneurial and technological ecosystem," says Christine Galib, senior director of programs at the Ion, in the release.

The Air Force announces 6 potential sites for Space Force base — and Houston misses the mark

Houston will not be considered for the Space Command HQ — but Texas isn't completely out of the running. U.S. Air Force Graphic by Rosario "Charo" Gutierrez

The United States Department of the Air Force announced the six candidate locations for the U.S. Space Command Headquarters — and Houston didn't make the cut.

The six locations include:

  • Kirtland Air Force Base in New Mexico
  • Offutt AFB in Nebraska
  • Patrick AFB in Florida
  • Peterson AFB in Colorado (where temporary operations are located)
  • Port San Antonio in Texas
  • Redstone Army Airfield in Alabama

The Air Force evaluated self-nominated cities from across 24 states based on factors related to mission, infrastructure capacity, community support, and costs to the Department of Defense, according to a press release. U.S. Space Command Headquarters location announcement is expected in early 2021.

"We are disappointed that Houston is not among the finalist locations for the U.S. Space Command," Susan Davenport, chief economic development officer for the Greater Houston Partnership, says in a statement to the Houston Chronicle. "We believe we put together a strong case for why Houston should be chosen. We will continue to work with the U.S. Air Force and other branches of the military on future opportunities and we will remain vigilant in our pursuit of aerospace industry opportunities for this region."

Rice Space Institute to collaborate with Canada

The Rice Space Institute has a new partner is Canada. Photo courtesy of NASA

Rice University's Rice Space Institute has signed a memorandum of understanding with the Consulate General of Canada in Dallas to collaborate on space science and technology.

The parties made the collaboration official at a virtual event on November 20. RSI Director David Alexander OBE, a Rice professor of physics and astronomy, says the partnership is key to the continued commercialization of space exploration.

"What's different about this agreement is that with the rapid growth of commercial space worldwide and the strength of the aerospace industry in Houston, it presents a new pathway for potential interactions between Canadian science and industry and commercial entities not just in the Houston region but around the world," he says in a news release. "It's a nice, complementary aspect to our connection with NASA."

The United States has collaborated with Canada on space exploration for decades, and Canada's government is committed to advancing space technology.

"This MOU with the Rice Space Institute comes at an exciting time in human space exploration," says Rachel McCormick, the Consul General of Canada in Dallas and Canada's official representative in the U.S. South Central region, in the release. "In 2019, the Government of Canada announced an investment of $1.9 billion over 24 years for the next generation of smart, AI-powered space robotics for the U.S.-led Lunar Gateway program.

"We are also providing $150 million over five years for the Lunar Exploration Accelerator Program," she continues. "LEAP will fund the development and demonstration of lunar science and technologies in fields that include AI, robotics and health."

Validere, a Canada-based energy logistics company, is expanding in Houston. Courtesy of Validere

Canadian startup fresh off $7 million seed funding raise picks Houston for U.S. expansion

Energy Tech

Houston's established reputation as the energy capital of the world combined with burgeoning tech scene has made the city attractive for a growing oil and gas company with roots in Canada.

Validere is an oil and gas company focused on using real-time data and both artificial and human intelligence insights to improve its clients' quality, trading, and logistics. The company's technology enhances the ability of oil and gas traders to make informed decisions, which currently are made based off unreliable product quality data. Annually, $2 trillion of product moves around the oil and gas industry, and Validere uses the Internet of Things to improve the current standard of decision making.

"It's like if you'd go to the grocery store to buy milk not knowing if it's 1 percent, 2 percent, or cream," co-founder Nouman Ahmad says about how companies are currently making oil and gas trading decisions.

In October, Validere concluded its seed funding round with $7 million. Among Validere supporters are several Silicon Valley power players, such as Sallyport Investments, Y Combinator, Real Ventures, Moment Ventures, and ZhenFund. The funds, in part, will help the company expand into the United States market.

"The goal in 2019 is to be at the same stage — in terms of customer success — in the U.S. market as we were at the end of 2018 in the Canadian market," Ahmad says.

The company has seen great success in Canada, and some of its existing clients have business in the Houston area already, Ahmad says.

With the increased focus on Houston comes a growing office. Currently, Ahmad leads the efforts in town with one other staffer, however, operations won't be a skeleton crew for too much longer. Ahmad says he is "aggressively hiring" in the Bayou City, which will be a key office for them as they grow across the country.

"As we think about the long-term future of the business, Houston is one of the most important markets for us going forward," Ahmad says.

Houston has been a welcoming community to the Canadian transplant, who says he spends most of his time here now. Both the startup and tech scenes in Houston have been valuable resources to the company — as has the energy industry's potential clients.

"Houston market is very receptive and ready for innovative companies that are solving problems for them," Ahmad says.

The company was founded in 2015 at Harvard by entrepreneurs who saw the potential for better transparency in the oil and gas industry. Validere's other co-founder and CTO, Ian Burgess, first had the idea for the technology after an accident happened in Canada; a train carrying crude oil derailed and blew up a small town killing 45 people.

"The industry largely bases important operational decisions on poor quality data," Burgess says in a release. "Our platform not only informs product quality reliably and in real time, but it also uses AI to help oil and gas companies optimize product movement."

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7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

5 must-read innovation headlines: Pharma giant considers Houston hub + more

Trending news

Editor's note: With May coming to a close, it's time to look back at the biggest innovation headlines for the second half of the month. Major moves were made in May, with NuScale Power entering the market, Persona AI inking a deal with Under Armour, and a pharma giant considering Houston for its next manufacturing hub. Here are the most-read InnovationMap stories published May 15-29, 2026:

1. Pharma giant considers Houston for $1 billion manufacturing campus

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub. According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

2. Modular nuclear reactor co. NuScale Power moves into Houston market

The nuclear energy renaissance continues in Texas with an announcement by NuScale Power. The Oregon-based provider of proprietary and innovative advanced small modular reactor (SMR) nuclear technology announced in April it would be opening office space in Houston’s CityCentre.

3. Persona AI teams with Under Armour to protect next-gen robots

Houston-based Persona AI has cemented a partnership with sportswear manufacturer Under Armour to provide materials to protect future robots operating in dangerous conditions. Through the partnership, Persona AI and Under Armour will launch a research initiative to explore whether advanced performance textiles can improve the durability and resilience of humanoid robots operating in harsh industrial environments.

4. Houston quantum energy chip startup emerges from stealth with $12M round

Houston-based Casimir has emerged from stealth with a $12 million seed round to commercialize its quantum energy chip. The round was led by Austin-based Scout Ventures. Lavrock Ventures, Cottonwood Technology, Capital Factory, American Deep Tech, and Tim Draper of Draper Associates also participated in the round. The oversubscribed round exceeded the company’s original $8 million target.

5. Global summit spotlights Houston's growing role in brain health, innovation

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. The summit, held June 9-10 at the Texas Medical Center's Helix Park, will bring together more than 500 executives, researchers, policymakers and innovators from around the world to discuss the global brain economy.

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