The winner of the Rice Business Plan Competition walked away with over $700,000 in prizes. Courtesy of Rice University

On Saturday, over 20 organizations were prepared to write checks to entrepreneurs competing in the Rice Business Plan Competition, but the largest and richest student business plan competition doled out almost double what it initially intended to award.

Earlier this year, Rice University announced the 42 teams that would be competing for $1.5 million in prizes, but ended up giving out a record $2.9 million. While a few organizations announced they had trouble picking a single company and named two recipients, Houston-based GOOSE Society surprised everyone with almost $1 million in unexpected prizes.

"It shows the diversity in expertise and interest of our investors, and how much the quality of the deals grown at RBPC," says Samantha Lewis, director at GOOSE.

GOOSE, which is a network of investors, originally intended to provide the grand prize — a $350,000 check to the company with the top score from the judges. The 2019 grand prize winner was Vita Inclinata Technologies, a company from the Mitchell Hamline School of Law that created a technology to advance helicopter safety. On top of that, GOOSE investors tacked on five more prizes.

  • $300,000 to Resonado, a more efficient speaker design company, from the University of Notre Dame
  • $200,000 to Rhaeos, a medical device company that has a wearable sensor for neurosurgical patients, from the Northwestern University
  • $200,000 to spotLESS Materials, a company that created a repellant coating material, from Penn State University
  • $125,000 to CataLight, a more sustainable water filtration system company, from the University of Waterloo
  • $100,000 to BrewBike, a campus bike delivery concept, from Northwestern University and the University of Chicago

GOOSE has surprised the crowd before at past RBPC awards banquets, Lewis says, but that's usually been one or two extra prizes. This is the first year the organization has committed this much — and there's potential for these companies to receive even more.

The group now begins is true due diligence process, Lewis says, and depending on what they find, they could invest more. The 2017 winner, Pennsylvania-based Forest Devices Inc., was awarded GOOSE's $300,000 grand prize, but the company eventually received a $2 million investment instead.

Two Houston-based student teams competed in the program, but neither were named even semifinalists. Curenav from University of Houston didn't receive any prize money, but Rice's LilySpec received the $25,000 Pearland Economic Development Spirit of Entrepreneurship Prize as well as the $1,000 Mercury Fund prize and the $1,000 Orrick Awards Banquet Company Showcase Prize.

The 19th annual contest named seven finalists according to the judges' top scores — all receiving over $100,000 in prizes each.

  • First place: Vita Inclinata Technologies (won a total value of nearly $700,000)
  • Second place: Resonado (won more than $300,000 )
  • Third place: spotLESS Materials (won more than $360,000)
  • Fourth place: Rhaeos (won more than $450,000)
  • Fifth place: Zilper Trenchless, which developed a way to install pipes under streets with minimum effect on the surface, from the Massachusetts Institute of Technology (won more than $435,000)
  • Sixth place: BrewBike (won more than $100,000)
  • Seventh place: CataLight (won more than $140,000)
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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.