Houston startup development organizations have banded together for the third annual Houston Innovation Summit. Getty Images

For the third year, The Houston Innovation Summit is taking over the town to promote entrepreneurship and innovation within the city.

THIS begins today and runs through the weekend. Each day represents a theme — all pertinent to Houston. Impact Hub Houston has worked with other local startup development organizations to curate the programming for the week. Grace Rodriguez, CEO and executive director for Impact Hub Houston, says Houston has the innovation infrastructure by now, and now it's about execution.

"For 2019, the goal is now how do we go from inclusion to integration," Rodriguez says on a recent episode of the Houston Innovators Podcast. "I think we're at that step now of becoming more inclusive as a community."

THIS, just like last year, runs on the same week of Global Entrepreneurship Week, which is why today's programming starts with a global focus. Follow along on a global scale with #GEWecosystems.

For a complete list of THIS events (most of which are free and all over town), head to the website. Here are the events you should make sure not to miss.

Monday — Houston: We're Global

Starting strong, the first can't-miss event is the kickoff party. The free event is in the Amegy Building downtown (1801 Main Street), which is currently being transformed into The Cannon Houston's new Launch Pad. The event runs from 4 to 5:45 pm, and you can expect networking and interactive discussions on Houston's innovation ecosystem's growth and potential. Click here to register.

Tuesday: This Is Houston

While GotSpot's Female Founder Luncheon at MassChallenge is a good one to make if you can, the big event this day is Houston Exponential's 2020 Vision event. Basically an open house-style event, attendees at this free event can learn how to engage with HX and what the organization has planned for 2020. InnovationMap and Accenture are teaming up for a fireside chat about the diversity and potential in Houston. Click here to register.

Wednesday: Fresh Perspectives

The fight for technology and innovation is on. The first Houston Digital Fight Club is on Wednesday, November 20, and will feature five fights between industry experts on topics like cybersecurity, sustainable energy, primary care, and more. Audience members get to decide on a winner, and there will be tons of opportunities for networking. The event is $30 per person and will be at White Oak Music Hall. InnovationMap and Accenture are the lead sponsors. Click here to register.

If you can't make this evening event, WeWork Food Labs is cooking up a special event to discuss food innovation in Houston. Click here to register.

Thursday: The Next Generation

While the week so far has been centered around the future of Houston, Thursday focuses specifically on the next generation of people who will be powering the ecosystem. And, of course, money is essential to that equation. Join for a panel from top investor leaders at an event focused on next generation investing at HCC SouthEast Felix Fraga Academic Campus - East End. The panel itself is $5, but for $15 you can also catch two other discussions on campus that day. Click here to register.

For an early bird alternative, Mercury Fund is hosting a Female Founders breakfast at 7:30 am at their office (3737 Buffalo Speedway, Suite 1750). This one is free to attend. Click here to register.

Friday: Integrating Innovation

Friday's events all take place at The Cannon Houston (1334 Brittmoore Road), and there's a specific focus on military technology and military-affiliated entrepreneurs. The Southwest Muster Across America Tour in Houston is from 1 to 6 pm and will consist of an expo, pitch competition, expert talks, and more. The WeWork Veterans in Residence Program Powered by Bunker Labs will show off their companies, and Bunker Labs has teamed up with Ford Fund to host pitch competitions for veteran and military spouse entrepreneurs. Houston is one of seven stops for the competition, and the top two showcase pitches will win $5,000 and $3,500 from the Ford Fund to help support their businesses. Click here to register.

Following this event is Impact Hub's monthly Fuckup Night, where entrepreneurs share their stories of success, struggle, and failure. Click here to register.

Weekend: Innovation Education

The week wraps up with events focusing on education. One not to miss is on Saturday: The HCC IDEAS Pitch Competition. The competition begins at 1 pm and there is $2,500 on the line. Any HCC student is able to apply to pitch. Click here to register.

Houston's seen the effect on climate change. Now, Impact Hub Houston is putting together a brainstorming event to find sustainable solutions. Getty Images

Houston organization to host a hackathon to find sustainable solutions to climate change

It's not easy being green

Houstonians are teaming up to put on a hackathon that will gather designers, developers, entrepreneurs, students, policymakers, and more to find sustainable solutions to climate change.

Impact Hub Houston is organizing Houston's fist Climathon for October 25. The local nonprofit is teaming up with global organizer EIT Climate-KIC, the City of Houston, Citizens' Environmental Coalition, Sketch City, January Advisors, Bunker Labs, WeWork Labs, Syzygy Plasmonics, and GoodFair.

"During Hurricane Harvey, we saw Houston's talent rise to these challenges and develop solutions that not only helped rescue, feed and shelter local Houstonians, but went on to help people in Florida and Puerto Rico," says Grace Rodriguez, CEO and executive director of Impact Hub Houston, in a news release. "We're excited to join the global Climathon challenge in order to give Houston's changemakers a platform to develop sustainable air, water, energy, etc., solutions and take them to the next level. In such a diverse city with so many resources, it seems only natural that Houston can help lead the way in developing local solutions that can scale to other contexts."

The city of Houston has seen its fair share of extreme weather as a result of climate change. The Energy Capital of the World among the highest per capita greenhouse gas emissions in the country, and mayor's office recently-announced Climate Action Plan to address the concerns of climate change.

"Houston has a lot to lose as the weather changes," says Jeff Reichman, founder of January Advisors and Sketch City, in the release. "We should be using our talents to elevate good ideas for our region, and to connect with one another for long-term collaborations."

The event will zero in on Houston's biggest emissions problems: transportation and commercial and residential buildings. The best ideas coming out of the Climathon will be sent to the international database for consideration for the global awards in Paris.

For more information and to register, view partnership opportunities, or sign up to volunteer, visit the website.

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Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.