Houston startup development organizations have banded together for the third annual Houston Innovation Summit. Getty Images

For the third year, The Houston Innovation Summit is taking over the town to promote entrepreneurship and innovation within the city.

THIS begins today and runs through the weekend. Each day represents a theme — all pertinent to Houston. Impact Hub Houston has worked with other local startup development organizations to curate the programming for the week. Grace Rodriguez, CEO and executive director for Impact Hub Houston, says Houston has the innovation infrastructure by now, and now it's about execution.

"For 2019, the goal is now how do we go from inclusion to integration," Rodriguez says on a recent episode of the Houston Innovators Podcast. "I think we're at that step now of becoming more inclusive as a community."

THIS, just like last year, runs on the same week of Global Entrepreneurship Week, which is why today's programming starts with a global focus. Follow along on a global scale with #GEWecosystems.

For a complete list of THIS events (most of which are free and all over town), head to the website. Here are the events you should make sure not to miss.

Monday — Houston: We're Global

Starting strong, the first can't-miss event is the kickoff party. The free event is in the Amegy Building downtown (1801 Main Street), which is currently being transformed into The Cannon Houston's new Launch Pad. The event runs from 4 to 5:45 pm, and you can expect networking and interactive discussions on Houston's innovation ecosystem's growth and potential. Click here to register.

Tuesday: This Is Houston

While GotSpot's Female Founder Luncheon at MassChallenge is a good one to make if you can, the big event this day is Houston Exponential's 2020 Vision event. Basically an open house-style event, attendees at this free event can learn how to engage with HX and what the organization has planned for 2020. InnovationMap and Accenture are teaming up for a fireside chat about the diversity and potential in Houston. Click here to register.

Wednesday: Fresh Perspectives

The fight for technology and innovation is on. The first Houston Digital Fight Club is on Wednesday, November 20, and will feature five fights between industry experts on topics like cybersecurity, sustainable energy, primary care, and more. Audience members get to decide on a winner, and there will be tons of opportunities for networking. The event is $30 per person and will be at White Oak Music Hall. InnovationMap and Accenture are the lead sponsors. Click here to register.

If you can't make this evening event, WeWork Food Labs is cooking up a special event to discuss food innovation in Houston. Click here to register.

Thursday: The Next Generation

While the week so far has been centered around the future of Houston, Thursday focuses specifically on the next generation of people who will be powering the ecosystem. And, of course, money is essential to that equation. Join for a panel from top investor leaders at an event focused on next generation investing at HCC SouthEast Felix Fraga Academic Campus - East End. The panel itself is $5, but for $15 you can also catch two other discussions on campus that day. Click here to register.

For an early bird alternative, Mercury Fund is hosting a Female Founders breakfast at 7:30 am at their office (3737 Buffalo Speedway, Suite 1750). This one is free to attend. Click here to register.

Friday: Integrating Innovation

Friday's events all take place at The Cannon Houston (1334 Brittmoore Road), and there's a specific focus on military technology and military-affiliated entrepreneurs. The Southwest Muster Across America Tour in Houston is from 1 to 6 pm and will consist of an expo, pitch competition, expert talks, and more. The WeWork Veterans in Residence Program Powered by Bunker Labs will show off their companies, and Bunker Labs has teamed up with Ford Fund to host pitch competitions for veteran and military spouse entrepreneurs. Houston is one of seven stops for the competition, and the top two showcase pitches will win $5,000 and $3,500 from the Ford Fund to help support their businesses. Click here to register.

Following this event is Impact Hub's monthly Fuckup Night, where entrepreneurs share their stories of success, struggle, and failure. Click here to register.

Weekend: Innovation Education

The week wraps up with events focusing on education. One not to miss is on Saturday: The HCC IDEAS Pitch Competition. The competition begins at 1 pm and there is $2,500 on the line. Any HCC student is able to apply to pitch. Click here to register.

Houston's seen the effect on climate change. Now, Impact Hub Houston is putting together a brainstorming event to find sustainable solutions. Getty Images

Houston organization to host a hackathon to find sustainable solutions to climate change

It's not easy being green

Houstonians are teaming up to put on a hackathon that will gather designers, developers, entrepreneurs, students, policymakers, and more to find sustainable solutions to climate change.

Impact Hub Houston is organizing Houston's fist Climathon for October 25. The local nonprofit is teaming up with global organizer EIT Climate-KIC, the City of Houston, Citizens' Environmental Coalition, Sketch City, January Advisors, Bunker Labs, WeWork Labs, Syzygy Plasmonics, and GoodFair.

"During Hurricane Harvey, we saw Houston's talent rise to these challenges and develop solutions that not only helped rescue, feed and shelter local Houstonians, but went on to help people in Florida and Puerto Rico," says Grace Rodriguez, CEO and executive director of Impact Hub Houston, in a news release. "We're excited to join the global Climathon challenge in order to give Houston's changemakers a platform to develop sustainable air, water, energy, etc., solutions and take them to the next level. In such a diverse city with so many resources, it seems only natural that Houston can help lead the way in developing local solutions that can scale to other contexts."

The city of Houston has seen its fair share of extreme weather as a result of climate change. The Energy Capital of the World among the highest per capita greenhouse gas emissions in the country, and mayor's office recently-announced Climate Action Plan to address the concerns of climate change.

"Houston has a lot to lose as the weather changes," says Jeff Reichman, founder of January Advisors and Sketch City, in the release. "We should be using our talents to elevate good ideas for our region, and to connect with one another for long-term collaborations."

The event will zero in on Houston's biggest emissions problems: transportation and commercial and residential buildings. The best ideas coming out of the Climathon will be sent to the international database for consideration for the global awards in Paris.

For more information and to register, view partnership opportunities, or sign up to volunteer, visit the website.

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New UH survey reveals concerns over AI data center growth in Houston

data findings

A new report out of the University of Houston shows that area residents remain wary of the long-term effects of operating data centers.

The recent survey from the University of Houston’s latest SPACE City Panel, conducted by the Center for Public Policy at the Hobby School of Public Affairs, shows that while 85 percent of Houston-area residents use AI, nearly 63 percent oppose the construction of AI data centers within 1 mile of their homes.

Respondents’ concerns centered around data centers’ high energy demand and the area’s power grid reliability. According to the survey, 32 percent of residents who oppose local data center projects would be more likely to support the centers if they relied on renewable energy over fossil fuels.

“Respondents understand that AI can bring economic and educational benefits, but they are also concerned about the physical infrastructure needed to fuel AI, especially data centers,” Soran Mohtadi, post-doctoral fellow at the Hobby School and a researcher on the report, said in a news release. “This physical infrastructure demands more electricity and water, leading to environmental impacts.”

Experts estimate that 6.5 gigawatts of data center capacity will be added to the Texas grid by 2030. And Houston’s data center capacity is predicted to more than double by 2028.

The Electric Reliability Council of Texas also projects electricity demand could reach 218 gigawatts by 2031, which would be more than double the record peak set in August 2023. Data centers are expected to account for 86 gigawatts of that new demand.

Survey respondents also said they are concerned about the state's future water supply, given the large amounts of water that data centers need to stay cool.

In terms of who’s responsible for that issue, 57.6 percent of respondents said they put the onus on Texas lawmakers, while 31.5 percent say tech companies should be responsible.

Additionally, more than 75 percent of respondents believed that data center developers and technology companies—not residents—should bear the cost of infrastructure upgrades to support data centers.

“Every decision legislators make has implications on residents’ everyday lives and local infrastructure now and in the future,” Maria P. Perez Arguelles, lead researcher on the report and research assistant professor at the Hobby School, added in the news release. “This issue is going to become more important in years to come, so this is just the beginning.”

Read the full report here.

Houston-born Cemvita makes breakthrough in sustainable fuel production

clean fuels

Houston-based biotech company Cemvita announced that it recently reached a critical milestone in the development of its FermOil product, which can be used to create Sustainable Aviation Fuel (SAF) and other renewable fuels at industrial scale.

The company shared in a news release that it completed a 75,000-liter industrial fermentation run at Belgium's Bio Base Europe Pilot Plant.

The campaign achieved target technical metrics for the production of FermOil, Cemvita’s renewable natural oil (RNO). FermOil is produced from industrial crude glycerin, an industrial byproduct, as opposed to traditional sugar-based feedstocks used in many bio-oil fermentation processes. It's designed to be a drop-in feedstock for creating SAFs.

Cemvita had previously advanced its FermOil production process through multiple scale-up stages before successfully reaching the 75,000-liter demonstration campaign, according to the company.

“This is not just a fermentation milestone,” Moji Karimi, CEO at Cemvita, said in the release. “It is a blueprint for how existing industrial infrastructure can evolve into circular bioeconomy infrastructure. Every biodiesel plant generating crude glycerin is a potential platform for renewable natural oil production.”

The milestone also supports the deployment of Cemvita’s industrial biomanufacturing platform, FermWorks, which integrates with existing energy and industrial infrastructure to turn waste carbon streams into SAFs and other materials. According to the release, Cemvita plans to move forward with commercial deployment discussions with partners in Brazil, Europe and in the UK. Cemvita already has a partnership with the Brazilian sustainable research institution REMA.

“We are proud to support innovative companies like Cemvita in scaling breakthrough industrial biotechnology solutions,” Hendrik Waegeman, head of business operations at Bio Base Europe Pilot Plant, added in the release. “Successfully operating at the 75,000-liter scale using a feedstock such as crude glycerin highlights both the maturity of the technology and the quality of the scale-up execution achieved by the Cemvita team.”

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Eli Lilly scoops up Houston biotech startup in $300 million deal

big pharma deal

Pharmaceutical giant Eli Lilly has acquired Houston biotech startup CrossBridge Bio, which develops antibody-drug conjugates for cancer, in a deal worth up to $300 million. The deal was celebrated by TMC Venture Fund and the University of Texas Health Science Center at Houston last week.

CrossBridge, founded in 2023, is developing ADCs based on research by Kyoji Tsuchikama and Zhiqiang An, both of UT Health Houston. Tsuchikama is an associate professor of medicinal chemistry and a globally recognized ADC pioneer, and An is a professor of molecular science and vice president of drug discovery.

Antibody-drug conjugates (ADCs) are a potent combination of targeted therapy and chemotherapy that kills cancer cells while saving healthy tissue.

Clinical trials for CrossBridge’s primary ADC candidate, CBB-120, are expected to start this year, pending approval from the U.S. Food and Drug Administration (FDA).

“I’m proud of how well our team has executed and advanced our platform in such a short time since the company’s founding,” Michael Torres, co-founder and CEO of CrossBridge, said in a news release. “By becoming a part of Lilly, a leader in patient-focused therapeutic development, we are well-positioned to further accelerate the clinical potential of this approach.”

Under the Lilly deal, CrossBridge shareholders were expected to receive an upfront payment along with a follow-up payment based on the achievement of certain milestones.

In 2024, CrossBridge closed a $10 million seed round. Among the investors in CrossBridge are the Texas Medical Center Venture Fund, CE-Ventures, Alexandria Venture Investments, Portal Innovations, Linden Lake Labs, and the Cancer Prevention and Research Institute of Texas (CPRIT). It was formed in TMC Innovation’s Accelerator for Cancer Therapeutics program."Built within the TMC ecosystem, CrossBridge Bio grew with the support, funding, and resources that helped shape its trajectory. TMC led the company's early financing and watched it evolve from its earliest days to its acquisition by Eli Lilly," William McKeon, president and CEO of the Texas Medical Center, shared in a LinkedIn post. "[This is a] strong reminder that breakthrough science and the right early backing can change what’s possible."