Rice University students and staff team up with Canadian company to make low-cost ventilators

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A Houston-based team of scientists and students have developed a low-cost ventilator. Photo courtesy of Rice University

As the COVID-19 case numbers continue to grow, hospitals around the world are either experiencing or expecting a shortage of ventilation units. In Houston, a team of students and staff at Rice University have designed a solution.

Along with Canadian global health design firm, Metric Technologies, the Rice team has developed an automated bag valve mask ventilator that can be crafted for less than $300. Moreover, the team expects to share the designs so that these low-cost machines can be produced everywhere.

The project is being called Take a Breather and was inspired by an early prototype that a group of engineering seniors developed in 2019 at Rice's Brown School of Engineering's Oshman Engineering Design Kitchen, or OEDK. The idea was to take a bag valve mask, which medical professionals use manually by squeezing with their hands, and create a device that can instead compress the bag automatically.

The parts of the device are largely created via 3D printing and laser cut, according to a press release from Rice, and only took around a week to prototype. While the original project was created to help emergency medicine professionals using a manual ventilator, the device is very relevant in the current coronavirus crisis.

"The immediate goal is a device that works well enough to keep noncritical COVID-19 patients stable and frees up larger ventilators for more critical patients," says Amy Kavalewitz, executive director of the OEDK, in the release.

As principal at Metric Technologies, Dr. Rohith Malya, who is assistant professor of emergency medicine at Baylor College of Medicine and an adjunct assistant professor of bioengineering at Rice, saw the growing need for for automated ventilator masks in emergency medicine.

"This is a clinician-informed end-to-end design that repurposes the existing BVM global inventory toward widespread and safe access to mechanical ventilation," Malya says in the release.

According to Malya, more than 100 million bag valve masks are produced annually. The designed device, which can work with these bags, has been named the ApolloBVM — a nod to when President John F. Kennedy announced from the Rice campus that it was his mission to get America to the moon.

"This project appeals to our ingenuity, it's a Rice-based project and it's for all of humanity," he says in the release. "And we're on an urgent timescale. We decided to throw it all on the table and see how far we go."

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3 Houston innovators to know this week

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As Houston transitions into summer, the city's tech and innovation ecosystem enters a new season — but with the same level of entrepreneurialism and can-do spirit.

This week's innovators to know includes a Houston tech founder fresh off fundraising, an architect with the future of the workplace, and a startup leader with a way to digitally connect churches to their congregations.

Joe Alapat, CEO and co-founder of Liongard

Courtesy of Liongard

After raising a $17 million round for his startup, Joe Alapat, CEO of Liongard, joined the Houston Innovators Podcast to discuss fundraising during a pandemic and how he's seen the Houston innovation ecosystem grow.

In the episode, Alapat also shares his advice for Houston startups looking to tap into the Houston innovation ecosystem — something he's watched grow over the past five years. Now, he says, when it comes to new startups in Houston, "the waves are hitting the shore."

"Houston has always been an entrepreneurial city, and this is just that next stage," Alapat says on the episode. "For me, it's the technology side that excites me even more to see technology companies really succeeding." Listen to the episode and read more.

Day Edwards, founder and CEO of Church Space

Photo courtesy of Church Space

Large gathering places have been shut down for months at this point, and that includes places of worship. Houston entrepreneur Day Edwards, founder and CEO of Church Space, usually focuses on connection organizations to spaces for worship or events. But, she is now focused on getting services online for congregations to connect with.

"It felt like the perfect opportunity to give churches a way to reach more people during the pandemic," says Edwards. "This would create more impact than anything we could possibly offer at this time." Read more.

Larry Lander, principal at PDR

Photo courtesy of PDR

While much of the country has been working from home for weeks, Larry Lander opines that this has made physical office space more important than ever.

"As a place to provide a technology offering we don't enjoy at our kitchen table, as a place to better support small group work beyond the tiny real estate of our laptop screens, and as a place that physically represents what our organizations are truly all about," he writes in a guest column for InnovationMap. The role of the workplace has never been more critical to business success." Read more.

Houston area gets failing score on social distancing, according to report

We got an F

According to a study that evaluated social distancing execution in counties, the Houston area didn't do so well and earned failing scores all around.

A widely used social distancing scoreboard from Unacast, a provider of location data and analytics, shows only one county in the Houston area — Austin County — received a grade above an F for social distancing as of May 20. But Austin County doesn't have much to brag about, since its social-distancing score is a D-. The Houston area's eight other counties, including Harris, flunked.

Relying on a huge storehouse of cellphone data, the Unacast scoreboard measures social distancing activity on a daily basis in every state and county compared with activity before the coronavirus outbreak. The scorecard assigns a letter grade of A through F based on current social-distancing behavior.

Each grade takes into account three factors:

Percentage change in average distance traveled compared with the pre-coronavirus period
Percentage change in visits to nonessential places compared with the pre-coronavirus period
Decrease in person-to-person encounters compared with the national pre-coronavirus average

So, how did Harris County, for instance, fare in those three categories? On May 20, its grade in each category was an F. Why? Because it had less than a 25 percent reduction in average mobility (based on distance traveled), less than a 55 percent reduction in nonessential visits, and less than a 40 percent decrease in "encounters density" compared with the national average.

The scoreboard indicates Harris County's grades have bounced around. On April 4, for example, Harris County received an A in the nonessential-visit category for reducing those visits by at least 70 percent.

Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine in Houston, said in an interview published May 20 that he's worried the easing of social distancing in Houston will lead to a spike in coronavirus cases.

"I think here in Houston we're underachieving in a lot of aspects in public health, and it's no fault of the … public health leaders," Hotez said.

In Texas, the Houston area isn't alone in its apparent failure, at least recently, to adhere to social-distancing guidelines.

On May 20, not a single county in the Austin, Dallas-Fort Worth, and San Antonio metro areas earned higher than a D on the Unacast report card.

All five counties in the Austin area got F's, as did all 13 counties in Dallas-Fort Worth, according to the scoreboard.

But as with Harris County, other metro areas' scores in individual categories have fluctuated over time. Here are a few examples:

On April 4, Travis and Dallas counties earned an A for at least a 70 percent reduction in nonessential visits.
On April 11, Tarrant County received a B for a 55 percent to 70 percent drop in average mobility.

In the San Antonio area, Bandera County earned the highest grade (D) of any county in the state's four major metros. Atascosa and Medina counties eked out grades of D-, while the remainder of the area's counties wound up in the F column.

In line with trends for its major-county counterparts, Bexar County's social distancing scores in individual categories have gone up and down. On April 11, for example, Bexar County earned a B for a 55 percent to 70 percent decline in average mobility.

The scores for the state's major metros appear to reflect the recent loosening of stay-at-home restrictions across Texas. But health experts still recommend sticking with social-distancing measures to slow the spread of the coronavirus. In fact, Unacast points out that the World Health Organization and the U.S. Centers for Disease Control and Prevention (CDC) cite social distancing as the "most effective way" to combat coronavirus infections.

Unacast says it launched the social-distancing scoreboard in March to enable organizations to measure and grasp the efficiency of local social-distancing efforts.

"Data can be one of society's most powerful weapons in this public health war," Thomas Walle, co-founder and CEO of Unacast, says in an April 16 release.

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This article originally ran on CultureMap.

Texas startup’s at-home COVID-19 test finally approved by feds

CORONAVIRUS RESPONSE

After its earlier effort was tripped up, Austin-based startup Everlywell on May 16 finally gained approval from the U.S. Food and Drug Administration to launch its at-home coronavirus test.

In a May 18 release, Everlywell says the self-administered test will be available later this month. The company, which specializes in at-home tests for an array of conditions, is the first to receive approval from the FDA for an at-home coronavirus test that's not associated with a lab or a manufacturer of diagnostic products.

The FDA's emergency authorization allows Everlywell to work with a number of certified labs that process authorized tests, rather than just a single lab.

"The authorization of a COVID-19 at-home collection kit that can be used with multiple tests at multiple labs not only provides increased patient access to tests, but also protects others from potential exposure," Dr. Jeffrey Shuren, director of the FDA's Center for Devices and Radiological Health, says in a release.

Everlywell's at-home test determines the presence or absence of the novel coronavirus, which causes COVID-19 illness. Everlywell's test kit uses a short nasal swab and includes:

A digital screening questionnaire reviewed by a healthcare provider.
Instructions on how to ship the test sample to a lab.
Digital results within 48 hours of the sample being received by the lab.
Results reviewed by an independent physician.

Anyone who tests positive test will receive a telehealth consultation. All positive test results are reported to federal and local public health agencies when mandated.

On March 23, Everlywell was supposed to start shipping 30,000 coronavirus test kits to U.S. consumers. But before a single test was sent, the FDA blocked distribution of at-home, self-administered tests from Everlywell and other companies. After that, Everlywell pivoted to supplying coronavirus tests to health care providers and organizations.

As with the company's previously approved coronavirus test, Everlywell says its test for individuals is sold at no profit. The $109 price covers costs such as overnight shipping to a lab, lab-processing fees, and kit components. Some health insurers cover coronavirus tests.

Everlywell says it's working with members of Congress to enable companies that are neither healthcare providers nor labs to be directly reimbursed by health insurers. The startup also is exploring how its coronavirus test could be made available for free.

"Widespread access to convenient testing will play a crucial role in the country's ability to address the pandemic and prevent overburdening our healthcare facilities. As the national leader in connecting people with high-quality laboratory testing, we are committed to fighting the spread of this virus in America," Julia Cheek, founder and CEO of Everlywell, says in the Everlywell release.

The company continues to supply its coronavirus tests to qualified healthcare organizations and government agencies.