Houston-based NextSeed has been approved as a broker-dealer platform, allowing for larger investments. Getty Images

NextSeed, which launched in Houston four years ago as a crowdfunding online investment platform, has expanded its services to become a broker-dealer. The platform also rolled out a new website.

Now that NextSeed Securities LLC is a SEC-registered broker-dealer, NextSeed campaigns aren't limited to the $1 million cap instated by crowdfunding rules, according to a news release. The new function also means that, rather than just debt securities (where investors are paid back based on revenue of the company), investors can also engage in equity investing (where money can be exchanged for ownership of the company).

"We previously focused only on debt securities, in part because we wanted to facilitate the right type of capital to the local small business community," says CFO Tae Mi Lee in the release. "With the launch of our broker-dealer practice, we are able to expand our services to offer both debt and equity offerings for different types of issuers and investors."

In the past, NextSeed deals have focused on local brick-and-mortar companies. However, this new capability opens doors to other types of deals.

"We have always wanted investors on the platform to have the ability to diversify their investment portfolios across multiple industries and asset classes, while providing the right investment structure for our business clients through a broader range of options," Tae Mi Lee continues. "We are excited about what this expansion means for our NextSeed community."

The broker-dealer model shifts more responsibility on NextSeed as the vehicle for trading securities, but also represents a growth in investing in Houston.

"The standards of review and compliance obligations for both issuers and investors become stricter and more comprehensive for offerings made via our broker-dealer, but we wanted to be able to offer a more extensive and flexible service to our community," says CEO and Co-Founder Youngro Lee in the release. "Since day one of our funding portal operations, we tried to adhere to certain standards above and beyond the minimal legal requirements. We're now just taking another leap forward into a new phase of NextSeed."

Since its launch in 2015, NextSeed has raised $11 million for companies on its platform. While not all in Houston, NextSeed focuses on funding its portfolio by locals who want to support nearby establishments. Here are some examples of deals made on the platform:

  • Buffalo Bayou Brewery in Houston raised $1,000,000.
  • Alkalign Studio in Menlo Park, California, raised $100,000.
  • The Native Hostel Bar & Kitchen in Austin raised $396,500.
  • Fair Isle Brewing in Seattle raised $327,800.

Earlier this year, NextSeed announced another new capability for its portfolio of companies. NextSeed Space launched to help provide local entities turnkey retail space with short-term leases. The space is located in Greenway Plaza, and the first tenant was announced as The Waffle Bus, however NextSeed moved in traditional Mexican restaurant, Tlahuac, which will reside in the food court until the end of June.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.