Many Houstonians are unemployed, laid off, or furloughed amid the pandemic. Others are literally burned out and ready for a life-altering career change. This expert has advice for both. Photo via Pexels

I've had so many pivots in my professional career; moving across the country, internal promotions, leaving a corporate job to launch my own company, and repositioning myself and my brand in new markets. But I'm one of those people who enjoy lots of change, and as I've continued in my career journey, I've found that those sentiments are not shared by many.

Making a career transition can not only be stressful for a majority of professionals but can paralyze people from making decisions that carry their livelihood alongside them. This is one reason I am fueled to help professionals, to be a support system for these complexities and helping them make decisions based on facts and strengths, not on fear.

As a career coach, it's my job to find a way to piece together years of experience for professionals in order to tell a story of growth, change, and transferable potential to sway key decision-makers for employment and economic opportunity.

Over the past several years, I've seen many trends in client challenges, storytelling similarities and developed a knack for helping people with complex stories make a successful career or entrepreneurial leap.

A new approach to career transitions

But then at the end of 2019, COVID-19 crept across Asia, slowly derailing markets, leading me to shift my focus to supporting my European clients as they began their lockdowns.

Job offers were being taken off the table, hiring freezes were put in place and travel required a two-week quarantine at either end. The fear in each of my clients' voices was palpable, and my resolve needed to be strong. I needed to stay steady, calm, and think more strategically than ever before to help them navigate this unchartered territory.

Within two months, the United States had been infiltrated by the virus, and the layoffs and furloughs began piling up. Now I was working across nations and states going through different phases of impact and needing to understand how to support these entrepreneurs and professionals in navigating through this.

Navigating the nuances of career change

What I realized is that I already had these answers. Navigating complexity has been my place of zen and working with intelligent, hungry individuals like yourselves continued to fuel my ability to innovate strategy and make a significant impact on career transitions.

I began to divide clients into priorities: furloughed and need work, laid off, overworked and need an exit, career epiphany, and entrepreneurs needing to reevaluate their business models.

If you were furloughed, there was a sense of hope, anxious to return to the workforce, and leaving bitterness for many when that call never came. In the state of Texas, 2.5 million professionals have lost their jobs, and only 1.8 million returned to work in 2021 to date.

In Houston, unemployment rates have maintained a high rate of about 8 percent in recent months. At the peak of COVID-19, the unemployment rates spiked significantly to more than 14 percent which translates to a large number of qualified people out of work.

Laid off and evaluating next steps

For those who were laid off, we had to evaluate financials. Was this a three-month endeavor or an ASAP, "my electricity will be shut off in two weeks if I don't find a job" scenario?

That dictated how we approached it. For the longer timeframe, we looked at roles carefully and targeted the best outcomes, tailored branding documents, and profiles and were highly intentional about applications.

In the second scenario, we made mandatory updates to branding and started the rapid apply approach to line up interviews quickly — even if it was going to be a short stint or a less than a glorious long-term option.

Overworked and anxious

Overworked and anxious to leave their jobs, this group had different desperation in their voice. They had previously enjoyed what they did, had an ambivalent outlook toward their employer, and thought things were 'going well.' This all changed when their support staff was sent home on furlough and those hours and that workload was enveloped by their department. These professionals felt blindsided.

How could things go from 'all is well' to 'get me out of here NOW!' in only a few short weeks? The mental, emotional, and physical stresses were and continue to be a leading factor in the rise in depression across the nation from 20 to 25 percent to 40 to 50 percent.

For this group of professionals, we focused on the role they had before the pandemic hit and those areas of fulfillment. We also focused on boundary setting to help support a move to a company where boundaries would need to be upheld to promote a healthier life balance.

Career epiphany clients

Next were my career epiphany clients. These professionals were awoken from the monotony that was once their career. Working from home, having different priorities, and learning to juggle many hats afforded new perspectives. This also meant that these professionals were no longer fulfilled in the direction of their careers, and were prepared to start anew.

This opened up an entire world of possibilities.

Unlike the career changes who had immediacy and trauma associated with their move, these epiphany clients were optimistic and strangely calm amidst the chaos and weight of this decision. Their priorities were no longer focused on one area but encompassed a much more holistic viewpoint.

And so, having the calm on our side, we would spend time working through their work attributes, close values, and defining their innate drivers in life. This work allowed us to choose roles that spoke to them.

Entrepreneurs

In the last group were my entrepreneurs. These business owners were looking at a brand new market and not knowing how to evolve their business model to fit the needs and budgets of their consumers. So many were filled with doubt on how they could ask for more money, or not have to increase their working hours to make the math work.

Our work felt like an enormous puzzle, putting all the right colors together first, then seeking out the corners and edges, until we could work toward the middle and most ambiguous pieces.

Together we redefined their clients (were they the same? Did they have the same needs now?) and how to best serve them. This required them to get out of their tried and true practices, as needs and budgets have also changed and evolved for their customers and clients. So we reverse-engineered into new pricing and service offerings that would provide immense value in a time when people needed it the most.

Each set of variables were unique, but the mindset and fears were so aligned with one another within each of these groups that I could provide streamlined tools that I knew would work to move the dial in their progression and overall success.

Innovative approach to career transitions

Utilizing resources that I already had, meant I just needed to find innovation in my approach. How was I to get professionals and entrepreneurs to learn and apply at rapid speed? How would I get through to them during this stressful time?

The approach was to give more actionable tools for them to leave each call with purpose and a sense of adventure ahead. I utilized a goal-setting sheet to identify priorities and lead from their reality, rather than standard best practices.

We focused on 4 key areas:

  1. Financials
  2. Growth
  3. Roles
  4. Timeline.

I realized that the biggest fears were in the unknown. So if we could start at a basic framework of knowing what they needed in order to pay bills and not disrupt life more, we could then focus on what was in their ideal, their wants, their bigger goals.

But I found that almost everyone trying to envision more money, or growth in roles during a global pandemic, didn't know how to focus on the future if they didn't know what needed to happen now, in the current state.

Everyone's reality was different, yet the momentum and freedom created by writing down their most vulnerable, essential needs, created a release in their energy and made conversation fill with hope. Having created a tangible plan of action had more impact than ever before. I took this momentum and challenged clients to do their homework, speak to their partners, their families.

With every group of transitioning professionals, this worked. My analogies and anecdotes changed and evolved as the year progressed, but this new starting point was the cornerstone to build confidence and momentum quickly.

Building a new path

As we start to see Texas opening up its businesses and mask requirements starting to shift, we will continue to see people in flux.

Overcoming storms, a pandemic, depression rates increasing, and an influx of new residents, the state will continue to find resilience. But professionals need to understand that before letting fear set in, there are steps you can take to release that pressure and build a new path, a new career, and a new story.

Understand and embrace your reality, write it down, uncover what is leading the fear, then take the first step to eliminate it.

Making a transition takes effort, but understanding your options based on your needs, and then your wants, will help create the movement you need to take that next step and keep moving in the right direction.

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Briar Dougherty, CEO and president of Career Organic, an Atlanta-based career coaching company.

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Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

Elon Musk's SpaceX site officially becomes the city of Starbase, Texas

Starbase, Texas

The South Texas home of Elon Musk’s SpaceX rocket company is now an official city with a galactic name: Starbase.

A vote Saturday, May 3, to formally organize Starbase as a city was approved by a lopsided margin among the small group of voters who live there and are mostly Musk’s employees at SpaceX. With all the votes in, the tally was 212 in favor to 6 against, according to results published online by the Cameron County Elections Department.

Musk celebrated in a post on his social platform, X, saying it is “now a real city!”

Starbase is the facility and launch site for the SpaceX rocket program that is under contract with the Department of Defense and NASA that hopes to send astronauts back to the moon and someday to Mars.

Musk first floated the idea of Starbase in 2021 and approval of the new city was all but certain. Of the 283 eligible voters in the area, most are believed to be Starbase workers.

The election victory was personal for Musk. The billionaire’s popularity has diminished since he became the chain-saw-wielding public face of President Donald Trump’s federal job and spending cuts, and profits at his Tesla car company have plummeted.

SpaceX has generally drawn widespread support from local officials for its jobs and investment in the area.

But the creation of an official company town has also drawn critics who worry it will expand Musk’s personal control over the area, with potential authority to close a popular beach and state park for launches.

Companion efforts to the city vote include bills in the state Legislature to shift that authority from the county to the new town’s mayor and city council.

All these measures come as SpaceX is asking federal authorities for permission to increase the number of South Texas launches from five to 25 a year.

The city at the southern tip of Texas near the Mexico border is only about 1.5 square miles (3.9 square kilometers), crisscrossed by a few roads and dappled with airstream trailers and modest midcentury homes.

SpaceX officials have said little about exactly why they want a company town and did not respond to emailed requests for comment.

“We need the ability to grow Starbase as a community,” Starbase General Manager Kathryn Lueders wrote to local officials in 2024 with the request to get the city issue on the ballot.

The letter said the company already manages roads and utilities, as well as “the provisions of schooling and medical care” for those living on the property.

SpaceX officials have told lawmakers that granting the city authority to close the beach would streamline launch operations. SpaceX rocket launches and engine tests, and even just moving certain equipment around the launch base, requires the closure of a local highway and access to Boca Chica State Park and Boca Chica Beach.

Critics say beach closure authority should stay with the county government, which represents a broader population that uses the beach and park. Cameron County Judge Eddie Trevino, Jr. has said the county has worked well with SpaceX and there is no need for change.

Another proposed bill would make it a Class B misdemeanor with up to 180 days in jail if someone doesn’t comply with an order to evacuate the beach.

The South Texas Environmental Justice Network, which has organized protests against the city vote and the beach access issue, held another demonstration Saturday that attracted dozens of people.

Josette Hinojosa, whose young daughter was building a sandcastle nearby, said she was taking part to try to ensure continued access to a beach her family has enjoyed for generations.

With SpaceX, Hinojosa said, “Some days it’s closed, and some days you get turned away."

Organizer Christopher Basaldú, a member of the Carrizo/Comecrudo Nation of Texas tribe, said his ancestors have long been in the area, where the Rio Grande meets the Gulf.

“It’s not just important,” he said, “it’s sacred.”

Texas-based 'DoorDash for laundry' startup tumbles into Houston market

No Scrubs

Laundry may seem like an endless task that piles up, but a new service offers a solution to overwhelmed Houston families.

NoScrubs, an Austin-based home laundry pickup service has just expanded to Houston. Described by the company as "DoorDash — but for laundry," they wash customer's clothes at local laundromats and return them the same day, folded and ready to be put away.

The service took off like gangbusters in Austin, making an expansion to the state's largest city an obvious choice. It's not universal coverage just yet.

For now, only the following ZIP codes have NoScrubs service available: 77002, 77004, 77005, 77006, 77007, 77008, 77009, 77010, 77018, 77019, 77024, 77025, 77027, 77046, 77056, 77057, 77081, 77098, 77401, 77030, 77003.

A single pickup starts at $40 for 20 pounds of laundry, while the basic monthly subscription is $60 for two pickups. All services use hypoallergenic detergents.

The average American family spends about 240 hours a year on laundry, making it a very time-consuming chore. For people with disabilities, difficult work schedules, and other circumstances, it can be a real help, says co-founder Matt O'Connor.

"Some of our favorite customer stories simply revolve around saving people time when they have something challenging going on," he writes in an email. "For example, one customer reviewed NoScrubs saying 'So happy I could cry! (Partially because I'm pregnant and my emotions are heightened!)...1000% recommend if you have time restrictions or physical restrictions! ' So, whether it’s saving time, the affordability, or the pleasantly surprising turnaround time, NoScrubs has a variety of benefits for any customer."

NoScrubs is also a new opportunity for Houston's gig workers. Because there are no passengers, it can be a safer alternative to driving ride share for women and other people apprehensive about having strangers in their cars. As NoScrubs partners with local laundromats, drivers are also going to centralized locations rather than all over the map, leading to less wear and tear on their cars. The laundromats benefit as well, since NoScrubs loads are ones that would otherwise be done at home.

"Our model makes driving a tiny fraction of the time, so folks who don’t want to wear down their vehicles and spend a ton on gas love working at NoScrubs," added O'Connor.