Many Houstonians are unemployed, laid off, or furloughed amid the pandemic. Others are literally burned out and ready for a life-altering career change. This expert has advice for both. Photo via Pexels

I've had so many pivots in my professional career; moving across the country, internal promotions, leaving a corporate job to launch my own company, and repositioning myself and my brand in new markets. But I'm one of those people who enjoy lots of change, and as I've continued in my career journey, I've found that those sentiments are not shared by many.

Making a career transition can not only be stressful for a majority of professionals but can paralyze people from making decisions that carry their livelihood alongside them. This is one reason I am fueled to help professionals, to be a support system for these complexities and helping them make decisions based on facts and strengths, not on fear.

As a career coach, it's my job to find a way to piece together years of experience for professionals in order to tell a story of growth, change, and transferable potential to sway key decision-makers for employment and economic opportunity.

Over the past several years, I've seen many trends in client challenges, storytelling similarities and developed a knack for helping people with complex stories make a successful career or entrepreneurial leap.

A new approach to career transitions

But then at the end of 2019, COVID-19 crept across Asia, slowly derailing markets, leading me to shift my focus to supporting my European clients as they began their lockdowns.

Job offers were being taken off the table, hiring freezes were put in place and travel required a two-week quarantine at either end. The fear in each of my clients' voices was palpable, and my resolve needed to be strong. I needed to stay steady, calm, and think more strategically than ever before to help them navigate this unchartered territory.

Within two months, the United States had been infiltrated by the virus, and the layoffs and furloughs began piling up. Now I was working across nations and states going through different phases of impact and needing to understand how to support these entrepreneurs and professionals in navigating through this.

Navigating the nuances of career change

What I realized is that I already had these answers. Navigating complexity has been my place of zen and working with intelligent, hungry individuals like yourselves continued to fuel my ability to innovate strategy and make a significant impact on career transitions.

I began to divide clients into priorities: furloughed and need work, laid off, overworked and need an exit, career epiphany, and entrepreneurs needing to reevaluate their business models.

If you were furloughed, there was a sense of hope, anxious to return to the workforce, and leaving bitterness for many when that call never came. In the state of Texas, 2.5 million professionals have lost their jobs, and only 1.8 million returned to work in 2021 to date.

In Houston, unemployment rates have maintained a high rate of about 8 percent in recent months. At the peak of COVID-19, the unemployment rates spiked significantly to more than 14 percent which translates to a large number of qualified people out of work.

Laid off and evaluating next steps

For those who were laid off, we had to evaluate financials. Was this a three-month endeavor or an ASAP, "my electricity will be shut off in two weeks if I don't find a job" scenario?

That dictated how we approached it. For the longer timeframe, we looked at roles carefully and targeted the best outcomes, tailored branding documents, and profiles and were highly intentional about applications.

In the second scenario, we made mandatory updates to branding and started the rapid apply approach to line up interviews quickly — even if it was going to be a short stint or a less than a glorious long-term option.

Overworked and anxious

Overworked and anxious to leave their jobs, this group had different desperation in their voice. They had previously enjoyed what they did, had an ambivalent outlook toward their employer, and thought things were 'going well.' This all changed when their support staff was sent home on furlough and those hours and that workload was enveloped by their department. These professionals felt blindsided.

How could things go from 'all is well' to 'get me out of here NOW!' in only a few short weeks? The mental, emotional, and physical stresses were and continue to be a leading factor in the rise in depression across the nation from 20 to 25 percent to 40 to 50 percent.

For this group of professionals, we focused on the role they had before the pandemic hit and those areas of fulfillment. We also focused on boundary setting to help support a move to a company where boundaries would need to be upheld to promote a healthier life balance.

Career epiphany clients

Next were my career epiphany clients. These professionals were awoken from the monotony that was once their career. Working from home, having different priorities, and learning to juggle many hats afforded new perspectives. This also meant that these professionals were no longer fulfilled in the direction of their careers, and were prepared to start anew.

This opened up an entire world of possibilities.

Unlike the career changes who had immediacy and trauma associated with their move, these epiphany clients were optimistic and strangely calm amidst the chaos and weight of this decision. Their priorities were no longer focused on one area but encompassed a much more holistic viewpoint.

And so, having the calm on our side, we would spend time working through their work attributes, close values, and defining their innate drivers in life. This work allowed us to choose roles that spoke to them.

Entrepreneurs

In the last group were my entrepreneurs. These business owners were looking at a brand new market and not knowing how to evolve their business model to fit the needs and budgets of their consumers. So many were filled with doubt on how they could ask for more money, or not have to increase their working hours to make the math work.

Our work felt like an enormous puzzle, putting all the right colors together first, then seeking out the corners and edges, until we could work toward the middle and most ambiguous pieces.

Together we redefined their clients (were they the same? Did they have the same needs now?) and how to best serve them. This required them to get out of their tried and true practices, as needs and budgets have also changed and evolved for their customers and clients. So we reverse-engineered into new pricing and service offerings that would provide immense value in a time when people needed it the most.

Each set of variables were unique, but the mindset and fears were so aligned with one another within each of these groups that I could provide streamlined tools that I knew would work to move the dial in their progression and overall success.

Innovative approach to career transitions

Utilizing resources that I already had, meant I just needed to find innovation in my approach. How was I to get professionals and entrepreneurs to learn and apply at rapid speed? How would I get through to them during this stressful time?

The approach was to give more actionable tools for them to leave each call with purpose and a sense of adventure ahead. I utilized a goal-setting sheet to identify priorities and lead from their reality, rather than standard best practices.

We focused on 4 key areas:

  1. Financials
  2. Growth
  3. Roles
  4. Timeline.

I realized that the biggest fears were in the unknown. So if we could start at a basic framework of knowing what they needed in order to pay bills and not disrupt life more, we could then focus on what was in their ideal, their wants, their bigger goals.

But I found that almost everyone trying to envision more money, or growth in roles during a global pandemic, didn't know how to focus on the future if they didn't know what needed to happen now, in the current state.

Everyone's reality was different, yet the momentum and freedom created by writing down their most vulnerable, essential needs, created a release in their energy and made conversation fill with hope. Having created a tangible plan of action had more impact than ever before. I took this momentum and challenged clients to do their homework, speak to their partners, their families.

With every group of transitioning professionals, this worked. My analogies and anecdotes changed and evolved as the year progressed, but this new starting point was the cornerstone to build confidence and momentum quickly.

Building a new path

As we start to see Texas opening up its businesses and mask requirements starting to shift, we will continue to see people in flux.

Overcoming storms, a pandemic, depression rates increasing, and an influx of new residents, the state will continue to find resilience. But professionals need to understand that before letting fear set in, there are steps you can take to release that pressure and build a new path, a new career, and a new story.

Understand and embrace your reality, write it down, uncover what is leading the fear, then take the first step to eliminate it.

Making a transition takes effort, but understanding your options based on your needs, and then your wants, will help create the movement you need to take that next step and keep moving in the right direction.

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Briar Dougherty, CEO and president of Career Organic, an Atlanta-based career coaching company.

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Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.

Houston quantum energy chip startup emerges from stealth with $12M round

seed funding

Houston-based Casimir has emerged from stealth with a $12 million seed round to commercialize its quantum energy chip.

The round was led by Austin-based Scout Ventures. Lavrock Ventures, Cottonwood Technology, Capital Factory, American Deep Tech, and Tim Draper of Draper Associates also participated in the round. The oversubscribed round exceeded the company’s original $8 million target, according to a news release.

Casimir’s semiconductor chips can generate power from quantum vacuum fields without the need for batteries or charging. The company plans to commercialize its first-generation MicroSparc chip by 2028.

The MicroSparc chip measures 5 millimeters by 5 millimeters and is designed to produce 1.5 volts at 25 microamps, comparable to a small rechargeable battery, without degradation and no replacement cycle.

“Casimir represents exactly the kind of breakthrough dual-use technology Scout Ventures was built to back,” Brad Harrison, founder and managing partner at Scout Ventures, said in the release. “This is based on 100 years of science and we’re finally approaching a commercial product … We’re proud to lead this round and support Casimir’s journey from applied science to deployed technology.”

Casimir says it aims to scale its technology across the ”full power spectrum,” including large-scale energy systems that can power homes, commercial infrastructures and electric vehicles.

Casimir's scientific work has been supported by DARPA-funded nanofabrication research and its technology was incubated at the Limitless Space Institute (LSI). LSI is a nonprofit that works to innovate interstellar travel and was founded by Kam Ghaffarian. Technology investor and serial entrepreneur Ghaffarian has been behind companies like X-energy, Intuitive Machines, Axiom Space and Quantum Space.

Harold “Sonny” White, founder and CEO of Casimir, believes the technology can power devices for years without replacements.

“Millions of devices will operate for years without a battery ever needing to be replaced or recharged because we have engineered a customized Casimir cavity into hardware capable of producing persistent electrical power,” White added in the release. “I spent nearly two decades at NASA studying how we power humanity’s future. That work led me to the Casimir effect and the quantum vacuum, where new tools have allowed us to build on a century of scientific knowledge and bring abundant power to the world.”