Houston institutions launch Project Metis to position region as global leader in brain health

brain trust

The Rice Brain Institute, UTMB's Moody Brain Health Institute and Memorial Hermann’s comprehensive neurology care department will lead Project Metis. Photo via Unsplash.

Leaders in Houston's health care and innovation sectors have joined the Center for Houston’s Future to launch an initiative that aims to make the Greater Houston Area "the global leader of brain health."

The multi-year Project Metis, named after the Greek goddess of wisdom and deep thought, will be led by the newly formed Rice Brain Institute, The University of Texas Medical Branch's Moody Brain Health Institute and Memorial Hermann’s comprehensive neurology care department. The initiative comes on the heels of Texas voters overwhelmingly approving a ballot measure to launch the $3 billion, state-funded Dementia Prevention and Research Institute of Texas (DPRIT).

According to organizers, initial plans for Project Metis include:

Creating working teams focused on brain health across all life stages, science and medical advances, and innovation and commercialization
Developing a regional Brain Health Index to track progress and equity
Implanting pilot projects in areas such as clinical care, education and workplace wellness
Sharing Houston’s progress and learnings at major international forums, including Davos and the UN General Assembly

The initiative will be chaired by:

Founding Chair: Dr. Jochen Reiser, President of UTMB and CEO of the UTMB Health System
Project Chair: Amy Dittmar, Howard R. Hughes Provost and Executive Vice President of Rice University
Project Chair: Dr. David L. Callender, President and CEO of Memorial Hermann Health System

The leaders will work with David Gow, Center for Houston’s Future president and CEO. Gow is the founder and chairman of Gow Media, InnovationMap's parent company.

“Now is exactly the right time for Project Metis and the Houston-Galveston Region is exactly the right place,” Gow said in a news release. “Texas voters, by approving the state-funded Dementia Prevention Institute, have shown a strong commitment to brain health, as scientific advances continue daily. The initiative aims to harness the Houston’s regions unique strengths: its concentration of leading medical and academic institutions, a vibrant innovation ecosystem, and a history of entrepreneurial leadership in health and life sciences.”

Lime Rock Resources, BP and The University of Texas MD Anderson Cancer Center served as early steering members for Project Metis. HKS, Houston Methodist and the American Psychiatric Association Foundation have also supported the project.

An estimated 460,000 Texans are living with dementia, according to the Alzheimer’s Association, and more than one million caregivers support them.

“Through our work, we see both the immense human toll of brain-related illness and the tremendous potential of early intervention, coordinated care and long-term prevention," Callender added in the release. "That’s why this bold new initiative matters so much."

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Eight Houston-area energy employers ranked on StartupBlink's new Corporate Startup Activity Index 2025. Photo via Getty Images

Houston energy giants rank high on new corporate startup activity report

startup support

Eight major players in Houston’s energy industry rank among the world’s top 20 energy companies for corporate startup activity.

The inaugural Corporate Startup Activity Index 2025, published by StartupBlink, ranks global corporations by industry. The eight Houston-area employers fall into the index’s energy and environment category.

Researchers from StartupBlink, an innovation research platform, scored more than 370 companies based on three factors: corporate involvement in startup activity, startup success and ecosystem integration.

The eight Houston-area energy employers that landed in the energy and environment category’s top 20 are:

No. 3 BP. Score: 13.547. U.S. headquarters in Houston.
No. 5 Saudi Aramco. Score: 7.405. Americas headquarters in Houston.
No. 7 Eni. Score: 6.255. Headquarters of Eni U.S. Operating Co. in Houston.
No. 8 Shell. Score: 6.217. U.S. headquarters in Houston.
No. 11 Occidental Petroleum. Score: 5.347. Global headquarters in Houston.
No. 15 Engie. Score: 3.352. North American headquarters in Houston.
No. 17 Repsol. Score: 2.980. U.S. headquarters for oil and gas operations in The Woodlands.
No. 19 Chevron. Score: 2.017. Global headquarters in Houston.

“Building a startup is hard, and navigating corporate innovation can be just as complex. This ranking is a step toward making the connection between startups and corporations more transparent, enabling startups and corporations to collaborate more effectively for mutual success,” said Eli David Rokah, CEO of StartupBlink.

Salesforce topped the global index with a score of 380.090, followed by Intel, Google, Qualcomm, and Comcast.

bp pulse plans to install a network of DC fast chargers at Waffle House locations in Texas, Georgia and Florida. Photo via Getty Images.

Ultra-fast EV charging bays coming to Waffle House locations in Texas and beyond

power breakfast

Scattered, smothered and ... charged?

Starting next year, EV drivers can connect to ultra-fast charging stations at select Waffle House locations throughout Texas, courtesy of bp pulse.

The EV arm of British energy giant bp announced a strategic partnership with the all-day breakfast chain this week. The company aims to deploy a network of 400kW DC fast chargers and a mix of CCS and NACS connectors at Waffle House locations in Texas, Georgia, Florida, and other restaurants in the South.

Each Waffle House site will feature six ultra-fast EV charging bays, allowing drivers to "(enjoy) Waffle House’s 24/7 amenities," the announcement reads.

“Adding an iconic landmark like Waffle House to our growing portfolio of EV charging sites is such an exciting opportunity. As an integrated energy company, bp is committed to providing efficient solutions like ultra-fast charging to support our customers’ mobility needs," Sujay Sharma, CEO of bp pulse U.S., said in a news release. "We’re building a robust network of ultra-fast chargers across the country, and this is another example of third-party collaborations enabling access to charging co-located with convenient amenities for EV drivers.”

The news comes as bp pulse continues to grow its charging network in Texas.

The company debuted its new high-speed electric vehicle charging site, known as the Gigahub, at the bp America headquarters in Houston last year. In partnership with Hertz Electrifies Houston, it also previously announced plans to install a new EV fast-charging hub at Hobby Airport. In a recent partnership with Simon Malls, bp also shared plans to install EV charging Gigahubs at The Galleria and Katy Mills Mall.

bp has previously reported that it plans to invest $1 billion in EV charging infrastructure by 2030, with $500 million invested by the end of 2025.

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A version of this article originally appeared on EnergyCapitalHTX.com.

This week's roundup of Houston innovators includes Ken Nguyen of bp, Paul Frison, and Alamgir Karim of University of Houston. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes an academic researcher, an energy tech leader, and a recently passed Houston innovation champion.

Ken Nguyen, principal technical program manager at bp

Ken Nguyen, principal technical program manager at bp, joins the Houston Innovators Podcast to discuss the company's new partnership with NASA. Photo courtesy of bp

The recently announced partnership between bp and NASA is a match made in Houston. The energy giant, which as its United States headquarters in Houston, entered into a Space Act Agreement with NASA to combine resources and efforts with innovation in mind.

"Houston has always been known as the Space City, and we're also known as the Energy Capital of the World, but there hasn't always been collaboration," Ken Nguyen, principal technical program manager at bp, says on the Houston Innovators Podcast. "The challenges that NASA is facing is very similar to the challenges that the oil industry faces — we operate in very harsh environments, safety is the most critical aspect of our operation, and now the economic business model for NASA has changed."

Nguyen explains that while both bp and NASA are navigating similar challenges and changes within their industry, they are going about it in different ways. That's where the opportunity to collaborate comes in. Read more.

Paul Frison, founder of the Houston Technology Center

Paul Frison, the founder of the Houston Technology Center, has died. Photo via dignitymemorial.com

The Houston innovation ecosystem is mourning the loss of one of its early leaders, Paul Frison, who died on September 5. He was 87.

A long-time Houston businessman, Frison founded the Houston Technology Center in 1999 and served as its CEO and president. The organization evolved into Houston Exponential several years ago. Frison remained active within Houston innovation until 2020.

“Paul Frison was a visionary and energetic leader who always presented a positive outlook on what the Houston technology entrepreneurship community could become," Brad Burke, associate vice president for industry and new ventures at Rice University's Office of Innovation, remembers. "He was one of the pioneers in the community who established the Houston Technology Center as one of the early leaders of the Houston ecosystem. I admired how he helped launch the ecosystem and created the platform for many others to build upon.” Read more.

Alamgir Karim, professor at the University of Houston

Alamgir Karim was instrumental in the new discovery. Photo Courtesy of University of Houston Office of Media Relations

A flask of Houston’s rain helped answer a long-running question about the origin of cellular life.

The solution is proposed by two University of Houston scientists, William A. Brookshire Department of Chemical Engineering (UH ChBE) former grad student Aman Agrawal (now a postdoctoral researcher at University of Chicago’s Pritzker School of Molecular Engineering) and Alamgir Karim, UH Dow Chair and Welch Foundation Professor of chemical and biomolecular engineering, and director of both the International Polymer & Soft Matter Center and the Materials Engineering Program at UH. They were joined by UChicago PME Dean Emeritus Matthew Tirrell and Nobel Prize-winning biologist Jack Szostak in an article published last week in Scientific Advances. Read more.

Ken Nguyen, principal technical program manager at bp, joins the Houston Innovators Podcast to discuss the company's new partnership with NASA. Photo courtesy of bp

Houston innovator breaks down industry silos with new bp, NASA partnership

houston innovators podcast episode 252

The partnership, which is still new and not fully fleshed out, will look at collaborative innovation into a few focus areas to start out with, including hydrogen storage and development, AI and general intelligence, robotics, and remote operations

"Houston continues to excel — in energy production and in space exploration — but by coming together," Nguyen says, "and for us to be able to tap into (NASA's) knowledge is tremendous. And we, within oil and gas, have a unique set of skills to blend into that with the hopes being that the city becomes this incubator for technology. The potential is there."

Nguyen oversees the implementation of new technologies at bp, and that includes software and hardtech, from cybersecurity to the digitization of the industry, which is an integral part of bp's energy transition plan, Nguyen says on the show.

"For bp, we do feel like as we transition as an international oil and gas company into an integrated energy company and we lean into the energy transition, the adoption of new technology is a critical part of making that viable for the planet and for the company," he says.

According to Nguyen, bp has invested its resources into exploring energy transition technologies like electric vehicle charging — including opening a fast-charging station at its Houston office — and renewable energy, including a solar farm about 10 miles northeast of Corpus Christi.

Another technology bp is keen on is digital twin technology, which can be crucial for enhancing safety for bp personnel and reducing emissions.

Nguyen says digital twin technology "allows us to be able to design and mirror scenarios with real-time variables, such as weather, off-take demands, and volatility."

The agreement will enable bp and NASA to collaborate on an array of technologies. Photo courtesy of bp

NASA, bp partner to share digital tech, expertise with new agreement

dream team

Houston-based energy company bp America is helping NASA boost U.S. space exploration efforts.

Under an agreement signed August 7, bp and NASA will share digital technology and technical expertise developed over several decades. The energy company says the deal will help advance energy production on earth, and will help advance exploration of the moon, Mars, and other planets.

For example, the agreement will enable bp and NASA to collaborate on an array of technologies. This includes digital models and simulations that let engineers and scientists visualize equipment in remote locations more than 7,000 feet underwater or millions of miles away on another planet.

The bp-NASA partnership evolved thanks to the Space Act Agreement. This agreement, part of the National Aeronautics and Space Act of 1958, allows NASA to work with companies, universities, and other entities to propel space exploration.

In a news release, Ken Nguyen, principal technical program manager at bp, says: “bp has built a proud legacy of technological innovation as we deliver the energy the world needs today while investing in the energy system of tomorrow. As NASA pursues a sustained presence on the moon and Mars, we see a unique opportunity for bp and NASA to work collaboratively on the forefront of digital technology that will cultivate further innovation in energy and space.”

Initially, bp and NASA will focus on developing standards, and expanding the capabilities of visualization and simulation models. Subsequent phases might include:

Exchanging practices surrounding safety, communication, artificial intelligence, and other aspects of remote operations.
Collaborating on renewable energy, such as hydrogen, solar, regenerative fuel cells, and high-capacity batteries.

“Both bp and NASA are custodians of deep technical expertise, working in extreme environments — whether that’s at the bottom of the ocean or on the moon,” says Giovanni Cristofoli, senior vice president of bp Solutions. “Sharing what we know with each other will help us solve complex engineering problems faster, meaning we can focus on keeping energy flowing safely and delivering higher margins with lower emissions.”

This won’t be the first time bp and NASA have teamed up. Offshore workers from bp have undergone underwater escape training at NASA's Neutral Buoyancy Laboratory, the astronaut training pool near Johnson Space Center. In addition, NASA has used bp’s Castrol lubricants for more than 60 years.

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This article originally ran on EnergyCapital.

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UH lands $1.2M NIH grant to fight superbugs using AI, quantum sensing

drug defense

The fight against antibiotic-resistant bacteria like MRSA is getting science fiction-like upgrades at the University of Houston thanks to a new four-year, $1.26 million grant from the National Institutes of Health.

The university says the recent funding brings total federal support up to $3.5 million for 11 years for the project, which uses AI and quantum-sensing technology to better understand how bacterial proteins develop resistance to drugs.

Any medical professional will tell you that one of the worst things that can happen is almost killing an infection. Bacteria that survive attacks from conventional antibiotic treatments emerge tougher, more resistant and more aggressive than before–making them much harder to treat. A good example is the superbug methicillin-resistant Staphylococcus aureus (MRSA).

UH chemistry professors Yuhong Wang and Shoujun Xu are working on this issue. They know full well that fighting superbugs requires new technology and new approaches, which is what they aim to pioneer with their new grant.

“Drug-resistant bacterial infections such as MRSA are becoming harder to treat, creating an urgent need for faster ways to understand how antibiotics and other small molecules interact with bacterial proteins,” Wang said in a news release.

Wang and Xu’s work centers around GTP, a cellular fuel that can cause tiny changes to a cell's structure when it mutates. Sometimes, those shape changes make it easier for drugs to breach the wall and attack the cells.

The UH scientists are employing AlphaFold, an AI-powered tool that can scan large molecular libraries in seconds. From these models, they can see promising drug combinations for future testing.

Once identified, the team uses their invention, super-resolution force spectroscopy, to monitor the cells. Tiny magnetic beads are attached to genetic material, then magnified to see how strong that material is when pulled. They can measure this incredible microscopic process through an atomic magnetometer, typically used in quantum physics. Combined, all these tools allow a high-definition look at how each molecule might respond to new chemical approaches.

“We're the only chemists in the world that use an atomic magnetometer for biological research,” Xu said. “It's a technique developed by physicists, and there is usually a gap between techniques developed by physicists and biological applications. Yuhong and I have been bridging that gap together for the past 10 years.”

Eventually, Wang and Xu hope to develop powerful software that can be used by drug manufacturers to model cellular responses. With enough predictive data, the software could even get ahead of superbugs’ own mutation, allowing drugs to be developed before new strains arrive.

"We want an algorithm where you input a protein sequence, score the mutation hotspots, and develop new inhibitors before a drug-resistant species even emerges," Wang added.

SpaceX to get more than 700 acres of Texas wildlife refuge in land swap

Space News

A federal judge on Monday, September 21, refused to block the Trump administration from giving SpaceX more than 700 acres of wildlife refuge as part of a land swap in Texas, while environmental groups vowed to continue their legal challenge.

U.S. District Judge Fernando Rodriguez Jr. declined the plaintiffs' request for a preliminary injunction to prevent the parcel exchange, saying they failed to prove it would worsen ecological risks to a Gulf Coast region already transformed by billionaire Elon Musk’s rocket operations.

In June, the U.S. Fish and Wildlife Service approved moving forward with the deal with SpaceX, which would surrender 683 acres the company owns in exchange for the federal land in the Lower Rio Grande Valley National Wildlife Refuge. The 103,000-acre refuge spans four counties along the Texas border and is home to animal habitats and historical landmarks.

Maps show the land SpaceX would acquire would be closer to the company's launchpad near the U.S.-Mexico border.

The swap amounts to a gift of public lands to SpaceX, “clearing the way for bulldozers to tear into this wildlife refuge as soon as next week and turn a public treasure into a private payday,” said Laiken Jordahl, a spokesperson with the Center for Biological Diversity, which filed the lawsuit alongside other opponents including tribal groups. Jordahl said Monday that the litigation will continue even as the exchange goes forward.

“This court order is not the final word. These lands hold incredible spiritual, historical and conservation value for the people and wildlife of South Texas. We won’t stop fighting to keep this irreplaceable public wildlife refuge safe from SpaceX bulldozers,” Jordahl said in a statement.

The lawsuit asks the federal court to halt the exchange, which has worried SpaceX opponents in the area who have long criticized the company's expanding footprint over lost access to beaches and concerns over exploding rockets.

The Fish and Wildlife Service didn’t respond to a request for comment on Monday’s decision. Previously, a spokesperson had said the agency does not comment on ongoing litigation.

The agency issued a final environmental assessment report in June that determined the exchange would cause no significant impact to the area. The report said the federal government believed the acquisition would represent a “net conservation benefit” and provide “substantial long-term conservation value and improving landscape-scale habitat connectivity across refuges in South Texas.”

The judge said that the plaintiffs offered “relatively weak” evidence of environmental harm.

“While they rightfully argue that the preservation of wildlife and historical lands furthers the public interest, they present no evidence demonstrating that the Property will suffer aesthetic, environmental, cultural, or historical degradation during the pendency of this lawsuit,” Rodriguez wrote in his ruling.

In addition, the judge said a preliminary injunction would result in modifications to SpaceX’s development plans, “placing additional hardship on the company’s ability to meet milestones and contractual obligations.”

SpaceX did not return an email seeking comment on the judge's ruling.

The space exploration company first broke ground in Texas more than a decade ago and has expanded rapidly, so much that SpaceX employees last year voted to incorporate their own local government called Starbase.

Rice Alliance, Greentown name winners of Houston Energy and Climate Week pitch competitions

winner winners

Approximately 100 startups from around the world pitched their breakthrough technologies and businesses during Houston Energy and Climate Week, with a select few taking home top prizes and bragging rights.

Each year, investors at the Rice Alliance Energy Technology Venture Forum name the 10 most-promising startups. Greentown's Climatetech Summit also culminates in a pitch event, where member companies can earn cash prizes.

Here's who won at two of the week's anchor events and competitions.

Rice Alliance Energy Tech Venture Forum

The 23nd annual event was held Thursday, Sept. 17, at Rice University’s Jones Graduate School of Business. The most-promising companies were selected by industry experts and participating investors attending the event.

The 10 most-promising companies included:

Australia-based Aquafortus, which has developed a non-thermal liquid to liquid desalination technology for resource recovery from wastewater brine
Houston-based Focis AI, which converts industrial laser scans into a queryable digital twin of refineries and plants
Houston-based ironlattice, a semiconductor manufacturing company
Houston-based Licube, which has developed technology to produce ultra-high-purity lithium compounds for the fusion energy, pharmaceuticals, semiconductors and high-performance solid-state battery sectors
Houston-based Mars Materials, a clean chemical manufacturing business that is working to convert captured carbon into resources, such as carbon fiber and wastewater treatment chemicals
Dallas-based MCatalysis, which has developed a suite of proprietary microwave-driven catalysts to produce high-quality, ready-to-use fuels compatible with existing infrastructure
Oslo, Norway-based OTee, an automation machinery manufacturer
Houston-based Pike Robotics, which deploys its Wall-Eye robot to inspect hazardous tanks without taking assets offline
New Mexico-based Spiritus, a direct-air-capture (DAC) technology company
San Francisco-based UptimeAI Inc., which develops AI reasoning agents for industrial operations teams

Stellai won the People's Choice Award. The Norwegian company develops AI products for the waste management industry.

The energy technology ventures selected to participate in the forum were named earlier this year. See the full list here, and read about last year's winners here.

Greentown Lab's Climatetech Summit

The annual summit was held Wednesday, Sept. 16, featured a number of Houston startups in its pitch competition and lighting pitch round. Judges included Dave Dreessen,, Jon Greene, Naval Preet Singh, Philip Llewellyn, Erin Madro, Justin Yeung, Jay Kim, Rawand Rasheed and Moji Karimi.

Pitch winners included:

First place: Elementium Materials' CEO Matthew Dawson, winning a $10,000 cash prize sponsored by TotalEnergies plus another $10,000 in legal services sponsored by Foley Hoag. The company develops advanced battery electrolytes. It is a Greentown Boston member; though Dawson is based in Houston.
Second place: Houston-based Solidec CEO and co-founder Ryan DuChanois, winning $5,000 in legal services sponsored by Foley Hoag. The company electrolyzes air, water and electricity into onsite hydrogen peroxide.

Lightening pitch winners included:

First place: Montana-based MagDrive Technologies, winning a $1,000 cash prize sponsored by Energy Transition Ventures. The company develops magnetically actuated, zero-emission valve systems that eliminate fugitive emissions and improve reliability.
Second place: Houston-based HEXASpec, winning a $500 cash prize sponsored by Foley Hoag. The company has created a new material to improve heat management for the semiconductor industry.

Read Greentown's recap of the summit here.

Houston Energy and Climate Week announced that the 2027 event will move to the spring, held April 4-10.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

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