3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Amanda Ducach of ema, Bobby Bryant of DOSS, and Abbey Donnell of Work & Mother. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from femtech to real estate — recently making headlines in Houston innovation.

Amanda Ducach, founder and CEO of ema

Amanda Ducach, founder of ema is launching her business's new product. Photo courtesy of SocialMama

Amanda Ducach set out to create a platform where mothers could connect with each other socially, but when she launched SocialMama just ahead of a global pandemic, she soon learned there was a bigger market need for access to information surrounding women's health — from fertility to menopause.

After pivoting her femtech platform to include women's health experts, she realized her technology wasn't able to completely support growing user base. The platform, which was called SocialMama, saw users engaging with experts in similar ways — and as Ducach looked into growing the platforms users, she realized that 24/7 access to experts was going to be hard to scale.

"We noticed that most of these conversations were repetitive," Ducach tells InnovationMap. "You had women asking an expert about tracking ovulation a hundred times a day. Having an OBGYN answer that question a hundred times a day was crazy and just not scalable." Read more.

Bobby Bryant, CEO and founder of DOSS

DOSS is a real estate platform founded in Houston that helps democratize access to homeownership. Photo via askdoss.com

Real estate and homeownership has been historically exclusionary. Bobby Bryant — the first Black man to create and franchise a real estate brokerage brand — wanted to do something about that.

Considering the history of the real estate industry — women weren't able to buy homes without being married and African Americans were refused outright thanks to the country's history of redlining — Bryant tells InnovationMap he saw an opportunity for a business.

“I look at diversity as our superpower, and I look at the opportunity to kick that door down," he says. Read more.

Abbey Donnell, founder of Work & Mother

Work & Mother is expanding. Photo courtesy of Work & Mother

Houston-based Work & Mother, which outfits commercial buildings with lactation accommodations for working parents, announced this month that it has entered into an agreement to open two new lactation suites outside the state of Texas.

The company, founded by Abby Donnell, will open suites in two commercial office buildings in Boston, Massachusetts, and Arlington, Virginia, just outside of Washington, D.C. The new suites are expected to be completed this summer.

Work & Mother currently has suites in Allen Center, The Jones on Main and Four Oaks Place in Houston, as well as East Lake at Tillery in Austin and Lincoln Centre in Dallas. Read more.

DOSS is a real estate platform founded in Houston that helps democratize access to homeownership. Photo via Getty Images

How this Houston innovator is tapping into tech to make homeownership more accessible

ask DOSS

Real estate and homeownership has been historically exclusionary. Bobby Bryant — the first Black man to create and franchise a real estate brokerage brand — wanted to do something about that.

“I look at diversity as our superpower, and I look at the opportunity to kick that door down," he says.

Bryant is the CEO and founder of DOSS, a digital brokerage that uses tech to make homeownership more affordable. DOSS is in the process of developing what Bryant describes as a “real estate super app.” The company, which was born in 2016, has developed a technology where customers are able to ask for real-estate advice and tips, search for home listings, get neighborhood information, and recent sales data.

The effort received funding via the Google for Startups Black Founders program, which totalled $100,000. DOSS touts its platform as a dynamic and effective effort to methodically dissect the entire real estate process and rebuild a modern-day digital real estate brokerage with a “flex-model” that's more modern.

Bryant is looking to grow DOSS using a franchise method. Franchisees get a program that lowers their expenses, increases their bottom line, and provides cutting edge technology that includes use of artificial intelligence. While the real estate space is competitive, and for some could be daunting, Bryant looks to modernize the industry, while making it simpler to navigate. And that's where the tech comes in.

“The fluidness of the process, not making it as restrictive to certain groups, it really opens things up, and that is what we’ve seen with our technology,” Bryant says. “How do we turn around and make data more humanistic and centralize it?

"We want people to feel comfortable asking questions and getting accurate answers," he continues. "Millenials and Gen Z are the most-educated generations we’ve seen in history. They are also the most diverse in history. We understand that."

Bryant explains how important equity and honesty is to these new generations, and he's built DOSS with them in mind. As a former educator with two master's degrees in education, Bryant transitioned to the world of real estate in 1999. He says he sees a connection in his journey from helping students to now helping people find a home — especially to these younger generations of first-time buyers who are dealing with an ever-changing market.

“Education is a part of all of our lives,” Bryant says. “I've been able to educate people on the process, and create a technology that makes it all more fluid, and insightful and transparent with the real estate industry. ... What I’ve done is incorporate an educational process, which I guess you can say is an advantage I have.”

Bobby Bryant founded Doss to make it easier to learn about homeownership. Photo via askdoss.com

What's the future of real estate — and how have technology and the pandemic affected its trajectory? A panel of experts discuss. Photo via Getty Images

Overheard: Houston experts weigh in on the future of tech in real estate

eavesdropping online

The residential and commercial real estate industries have both evolved drastically as new technologies have emerged and in light of the pandemic. But where does that leave renters, homeowners, Realtors, brokers, and everyone else?

A panel of experts looked into their crystal balls and tried to answer this question at a panel for Houston Tech Rodeo last week. They discussed diversity and inclusion, home buying and rental trends, post-pandemic office design, and more on the virtual panel moderated by Allen Thornton, CEO of Money For Your Mission.

To hit the highlights from the virtual panel, check out some overheard moments below. To stream the full broadcast, click here.

“We’re dealing with a different consumer. When you look at the largest pool of buyers of residential real estate — it’s millennials.”

— Bobby Bryant, CEO of Ask Doss. Bryant says these buyers want information than just pictures, square footage, and the school it's zoned to. They want to know about the neighborhood they will be a part of.

“Folks are realizing how much waste comes from buildings — the buildings we spend 90 percent of our time in.”

— Natalie Goodman, CEO of Incentifind. She adds that renters and homebuyers, as well as commercial tenants, are increasingly demanding more sustainable options. And the government will pay you to implement these things, Goodman says.

“Before the pandemic, there were already over 60 million freelancers across the country. If the pandemic has taught us anything, it’s that a whole lot more people than just that 60 million are capable of doing a really fantastic job of powering the economy from home."

— Reda Hicks, CEO of GotSpot. People are going to be using space differently, so it's about finding those needs and providing the right access to them.

“As human beings, we’ll be drawn to operating and cooperating with other people in environments that are conducive to collaborating and creativity. We’ll probably see innovation ecosystems transition their operational pieces to an online platform. … But we’ll just naturally want to engage with other humans again."

— Alexander Gras, managing director of The Cannon. Gras adds that the opportunity for in-person collisions is too important to us as humans.

“People are getting educated and educating themselves, and there’s more inclusion. That means more opportunities for individuals of color to invest in or own residential or commercial real estate.”

— Mark Erogbogbo, influencer at 40 Acre Plan. These emerging opportunities, he adds, need to continue.

“When you don’t need to go to a specific office every day and you can work anywhere, well then you can live anywhere.”

— Sebastien Long, CEO of Lodgeur. The pandemic changed how people regarded their housing. Many opted for more spacious rentals with backyards in less crowded areas. Americans don't have a much time off as Europeans, he adds, so they are rethinking how they work remotely.

“Residential real estate has to be the only industry that sells a product that it doesn’t service.”

— Bryant says, explaining how homebuying is one of the most expensive purchases in people's lives that they use for 8 years on average, yet it's a one-time transaction that also spans across many platforms. "The future of real estate brings everything together in one place."

“What CRE needs to think about if they are going to attract and retain tenants … then they need to think about resilience and build for more extreme weather. And that’s where incentives are going to spike.”

— Goodman adds, referencing the winter storm and the hurricanes Houston gets every season.

“For a very long time, (commercial real estate) has been an industry based on a 10-year lease. There are few people who are willing to take on that kind of relationship because that’s a decade, and nobody knows what’s going to happen tomorrow.”

— Hicks says about the challenge CRE owners face with finding new tenants.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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